Finally out! A small screen helps understand a little more about how E. coli regulates major transporters, and reveals how caffeine induces phenotypical antibiotic resistance. Huge thanks to collab @andrenmateus.bsky.social (Umeå) and Christian L. Müller (Munich)! journals.plos.org/plosbiology/...

New preprint out: www.biorxiv.org/content/10.1... We followed up on our recent Nature Genetics paper mapping Shigella colonization in intestinal organoids with a deep dive into one of the screen hits: pcnB. #Shigella #virulence #microsky

Our latest work combines human gut epithelial #organoid culture with experimental #Shigella #infections, transposon mutagenesis, and statistical modeling. This has led to the mapping of the comprehensive geneset that drives Shigella epithelial colonization. Out @natgenet.nature.com: rdcu.be/eqGgf

Do we really know the antibiotics that we already have? Check out our story on 60y old drug nitroxoline and its new tricks! @goetheuni.bsky.social @embl.org www.nature.com/articles/s41... + great piece from the synchrotron @esrf.fr where we chased nx effects on metals www.esrf.fr/home/news/ge...

Looking forward to speaking in this webinar series next Wednesday.

So happy to see the first paper on research from the lab out! Just a review for now, but it gives an idea of the avenues we are exploring.

We have a PhD student position open in the context of the ENDAMR doctoral network. Deadline is 31/May. Apply here: umu.varbi.com/en/what:job/...

Looking forward to sharing with this community what our lab is doing