Simon Gates
@sim0ngates.bsky.social
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I have no need of that hypothesis.
We need a new word - "corruption" isn't nearly strong enough
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3 days ago
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Cold War Steve
12 days ago
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Cold War Steve
29 days ago
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Prof Christina Pagel
12 days ago
The shooting of Alex Pretti was (US) state sanctioned murder and has been followed up by attempts to destroy evidence and stop local police (and even the FBI) from investigating. Minnesota police are trying to counter the lies and illegality. Terrifying
open.substack.com/pub/heatherc..
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https://open.substack.com/pub/heatherc..
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Liam Thorp
12 days ago
Worth remembering when looking at the horrific scenes in the US right now that both Reform and the Tories have pledged to bring in ICE-style organisations to the UK if they win power
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Cold War Steve
15 days ago
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John Bull
16 days ago
The US granted visas to Jews but only allowed 30,000 in from Germany a year. You had to wait for your number to come up. Meet Robert Smallbones. An unassuming British diplomat who 'hacked' this system so effectively (saving 48 THOUSAND Jews) the UK government kept his scheme secret for decades /1 🧵
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Good news - just a shame that this story has to include Conservative and Reform politicians saying stupid things, and not pointing out how idiotic they are.
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16 days ago
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Absolutely
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17 days ago
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Phil Lewis
18 days ago
Dr. Gladys West, the pioneering mathematician whose work laid the foundation for modern GPS technology, has died. She was 95.
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Dr. Gladys West, Mathematician Whose Work Made GPS Possible, Dies at 95
ALEXANDRIA, VA — Dr. Gladys West, the pioneering mathematician whose work laid the foundation for modern GPS technology, has died. She passed away
https://thezebra.org/2026/01/18/dr-gladys-west-mathematician-whose-work-made-gps-possible-dies-at-95/
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Cold War Steve
18 days ago
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Cold War Steve
19 days ago
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Joe Bak-Coleman
20 days ago
Constructively, a lot of the replies seem to feel seen (the pain?) of this post. It can be hard to write up Bayesian credible regions when you know your paper is headed for reviewers who will write back "yeah but is it significant?" Here's my brief advice:
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Julia M. Rohrer
21 days ago
wake up babe, new effect size metric just dropped
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This is excellent
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21 days ago
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Jonathan Bartlett
22 days ago
'How to interpret hazard ratios', with
@dominicmagirr.bsky.social
and
@timpmorris.bsky.social
thestatsgeek.com/2026/01/15/h...
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How to interpret hazard ratios
Survival analysis of time-to-event outcomes is very commonly performed using Cox’s famous proportional hazards model. The model estimates hazard ratios for the ‘effects’ of covari…
https://thestatsgeek.com/2026/01/15/how-to-interpret-hazard-ratios/
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Frank Harrell
24 days ago
FDA drugs and biologics guidance for Bayesian clinical trials is something I've been dreaming of for decades. I am thrilled that this draft has been released!!
#Statistics
#StatsSky
#fda
#clinicaltrial
#bayes
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Only fair to share this widely
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25 days ago
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Leader of the opposition, folks
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25 days ago
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Justin
27 days ago
“Uruguay did what most nations still call impossible: it built a power grid that runs almost entirely on renewables—at half the cost of fossil fuels. The physicist who led that transformation says the same playbook could work anywhere—if governments have the courage to change the rules.”
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Uruguay’s Renewable Charge: A Small Nation, A Big Lesson For The World
Uruguay built a power grid that runs 99% on renewables—at half the cost of fossil fuels. Here’s how its bold energy overhaul became a global model.
https://www.forbes.com/sites/kensilverstein/2025/10/19/uruguays-renewable-charge-a-small-nation-a-big-lesson-for-the-world/
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Arthur Snell
25 days ago
If you think of Trump as an absolute monarch, with no distinction between his personal wealth and power and that of the United States, things start to make a bit more sense. He's like a crap Louis XIV.
open.substack.com/pub/arthursn...
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L'État, c'est moi
From Sun King to Spray-Tan King
https://open.substack.com/pub/arthursnell/p/letat-cest-moi?r=8jnwf&utm_campaign=post&utm_medium=web&showWelcomeOnShare=true
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This is so mad
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25 days ago
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Stefan Siebert
26 days ago
Beyond the personal tragedy, this will be a permanent stain on the UK and its reputation as a civilised country and society (and likely shift the window on indefinite detention). Why should any other country listen to the UK lecture them about protecting people's right to protest!
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Incredibly scary... If he does, the same world needs to step up, or we're completely screwed.
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27 days ago
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World's best bird
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27 days ago
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Simon Gates
Carla Denyer
29 days ago
The Palestine hunger strikers have been on hunger strike for over 60 days and are close to death. They have not even been convicted of a crime - they are being held on remand (pre-trial) for more than twice the max time allowed, and counting…🧵
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Cold War Steve
about 1 month ago
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Ruth Deyermond
about 1 month ago
It's New Year, so time to look back and forward. These are 10 things I think we need to recognise in 2026. It’s a response to what I think are profoundly damaging mistaken assumptions I’ve heard and read from practitioners, journalists, and analysts in 2025. Warning: very long🧵
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Ed Morrish
about 1 month ago
i post this story every christmas, and will keep doing so until it stops making me cry merry christmas xx
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A real Good Samaritan
One act of kindness that befell Leeds writer Bernard Hare in 1982 changed him profoundly. Here he tells his story.
https://www.bbc.co.uk/news/magazine-12043294
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Cold War Steve
about 1 month ago
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Sarah Murphy
about 1 month ago
Letter to the FT that stingingly sums up Brexit and the shit creek we now find ourselves in. A terrible idea (naive, prejudiced and uninformed) that has deeply divided us and left us poorer and less secure… but unwilling to face up to the damage we’ve done to ourselves. While the EU moves on.
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Marion Campbell
about 2 months ago
It’s the run up to the holidays so there can only be one
#MethodologyMonday
topic - the scientific way to cut your Christmas cake. Published c1906 in Nature by the statistician Francis Galton 🎂🎄🔪😊 Enjoy!
galton.org/essays/1900-...
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Joe Bak-Coleman
about 2 months ago
Reading the structured abstract alone should set off a half dozen statistical alarms in any scientists head. The fact that this found its way into Science makes me wonder how we drive home those stats 101 lessons and make them intuitive.
www.science.org/doi/10.1126/...
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Recent discoveries on the acquisition of the highest levels of human performance
Scientists have long debated the origins of exceptional human achievements. This literature review summarizes recent evidence from multiple domains on the acquisition of world-class performance. We re...
https://www.science.org/doi/10.1126/science.adt7790
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Cold War Steve
about 2 months ago
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Louise, Prof/Dr
about 2 months ago
Utterly ridiculous to compare a far right racist with a Green Party leader who is currently demonstrating better socialist credentials than the so-called Labour party. If Labour doesn't realise soon that it's the progressive voters it needs to appeal to, not the Reform ones, it's game over.
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Ben Bolker
4 months ago
evergreen: splaytree, dir. 2010. Biologist Talks to Statistician. 3:32.
www.youtube.com/watch?v=Hz1f...
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Biologist talks to statistician
YouTube video by RunProgramRun
https://www.youtube.com/watch?v=Hz1fyhVOjr4
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Andrew Urquhart
about 2 months ago
Encouraging stats here showing 26% reduction in the number of deaths after a default 20mph was introduced in Wales. That's about the same as the benefit from introducing seat belts, which also caused opposition at the time, but a change that we now all accept.
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Gary Collins
about 2 months ago
ICYMI: "Clinical prediction models using machine learning in oncology: challenges and recommendations" -->
bmjoncology.bmj.com/content/4/1/...
#machinelearning
#digitalhealth
#predictionmodels
#methodsmatter
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Clinical prediction models using machine learning in oncology: challenges and recommendations
Clinical prediction models are widely developed in the field of oncology, providing individualised risk estimates to aid diagnosis and prognosis. Machine learning methods are increasingly being used t...
https://bmjoncology.bmj.com/content/4/1/e000914
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Cold War Steve
over 1 year ago
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Cold War Steve
about 2 months ago
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The BMJ
about 2 months ago
Doug Altman was an internationally renowned statistician who served as The BMJ’s chief statistical adviser. Read about life and work that made this statistician a "citation millionaire"
#BMJChristmas
www.bmj.com/content/391/...
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Outstanding work
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about 2 months ago
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Simon Gates
about 2 months ago
Selection bias is important
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Christopher McCabe
about 2 months ago
Some thoughts on the implications of NICE Cost Effectiveness Threshold as an instrument of industrial policy.
christophermccabe.substack.com/p/time-to-ge...
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Time to get serious about the societal value of new drugs.
The NICE way to invest in the United Kingdom's life and health sciences sector
https://christophermccabe.substack.com/p/time-to-get-serious-about-the-societal
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"created an "aura" around the USA..." That's one way of putting it
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about 2 months ago
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Prof Christina Pagel
2 months ago
Breaking down some of the anti Vax stuff going at the CDC *before* this week's ACIP meeting on childhood vaccines. Notably their "finding" on COVID vaccines and children and a recent appointment...
youtube.com/shorts/AR97l...
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Why the FDA memo on COVID vaccine risk is nothing to worry about
YouTube video by Professor Christina Pagel
https://youtube.com/shorts/AR97lIVjevw?si=Hle2on3YqqEdx9ah
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More on single arm trials (stop me if you think you've heard this one before). I'd actually really like someone to argue against what I'm saying here. There are loads of trials like this one, which seems problematic.
simonelgato.github.io/2025/12/06/n...
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Single arm neuroblastoma trial
This post is about this trial: Furman et al. A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma. Clin Cancer Res (2019...
https://simonelgato.github.io/2025/12/06/neuroblastoma-single-arm.html
2 months ago
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So if leaving the EU was a really bad idea, then we should... Come on Keir, you're nearly there
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2 months ago
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Simon Gates
Michael "Shapes Dude" Betancourt
2 months ago
So much statistics discourse orbits around Bayes verses frequentist debates, but in practice Bayes verses frequentist is often a false dichotomy. Just as important as the inferential strategy is the underlying model, and how that model is specified. 🧵
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