Next Thursday (23rd July), joins us online or at LSHTM for a @lshtm-dash.bsky.social seminar by Mia Tackney (MRC BSU) on her work 'Capturing the curve: Functional data analysis for validated digital outcome measures'. More details here: www.lshtm.ac.uk/newsevents/e...

New paper 'The role of post intercurrent event data in the estimation of hypothetical estimands in clinical trials', now available in Statistics in Biopharmaceutical Research doi.org/10.1080/1946... and open-access at researchonline.lshtm.ac.uk/id/eprint/46...

Thursday 11th June, join us at LSHTM or online to hear from Rebecca Whittle on 'How large is large enough? Sample size calculations for clinical prediction models'. Further details here: www.lshtm.ac.uk/newsevents/e... @lshtm-dash.bsky.social

Perspectives on statistics in medicine: Annual joint LSHTM/RSS lecture on 16th June, by Prof. Marion Campbell. Further details here: www.lshtm.ac.uk/newsevents/e...

A few places left on our online 3 day course on multiple imputation for missing data...

Come and join us this Tuesday to hear 'The test negative design: What bias is it intended to address?' @lshtm-dash.bsky.social www.lshtm.ac.uk/newsevents/e...

Please join us in person or online @lshtm-dash.bsky.social on 26th February to hear about @georgiatomova.bsky.social's recent work on 'How can different modes of survey data collection introduce bias?' www.lshtm.ac.uk/newsevents/e...

'How to interpret hazard ratios', with @dominicmagirr.bsky.social and @timpmorris.bsky.social thestatsgeek.com/2026/01/15/h...

@lshtm.bsky.social will be running a 3-day online short course on using multiple imputation to handle missing data on 23-25th June 2026. Teaching staff include James Carpenter, Ruth Keogh, Clémence Leyrat, and myself. Further details about the course at www.lshtm.ac.uk/study/course...

🥳 Registration for abstracts for EuroCIM 2026 (Oxford) is now OPEN and the deadline for submissions is 9 January 2026: eurocim.org/oxford-2026/... 👉 Theme? “Causal inference in health, economic and social science” 👉 When? April 14-17 👉 Where? Oxford 👉 Register? eurocim.org/oxford-2026/...

New PhD position available at @mrcctu.bsky.social to develop guidance on balancing statistical and clinical considerations when choosing an estimand in RCTs. www.findaphd.com/phds/project...

Thinking of performing a quantitative bias analysis for measurement error or misclassification? Then our recent software review, by Codie Wood, Kate Tilling, myself and Rachael Hughes, may be of interest: rdcu.be/eDRn2

Are estimands being correctly used? A new review of protocols led by Timothy Clark shows many incorrectly defined estimand attributes. See the top areas for improvement & full results here: trialsjournal.biomedcentral.com/articles/10.... #Trials

September @vicbiostat.bsky.social seminar: Camila Olarte Parra from @causalab.bsky.social Karolinska will speak on combining information from trial participants and non-participants in registry-based trials. All welcome online 25 September. More info: www.vicbiostat.org.au/event/combin...

We are recruiting a Research Fellow to develop machine learning based methods for handling missing data @lshtm.bsky.social. See jobs.lshtm.ac.uk/vacancy.aspx... for more details.

We are looking forward to hearing @jonathan-bartlett.bsky.social speak on the G-formula for causal inference using synthetic multiple imputation at the July @vicbiostat.bsky.social seminar! All welcome online Thursday 24th, 4:00pm Aus EST (7:00am UK time). www.vicbiostat.org.au/event/g-form...

HIRING! 2 PhD openings within the “Safe Causal Inference” consortium with experts from biostatistics, computer science, math, and epidemiology. You'll develop new methods to evaluate prediction algorithms that take the causal effect of treatments into account. 👉 www.lumc.nl/en/about-lum....

1/ NEW R PACKAGE! For estimating the impact of potential interventions on multiple mediators in countering exposure effects (led by @cttc101.bsky.social) - Paper👉 tinyurl.com/ye26jsps - Package👉 tinyurl.com/yuh4kens Thread shows published examples of how the method can be used! #EpiSky #CausalSky

📣 Calling everyone working in #datascience #biostatistics #clinicaltrials We’re bringing together experts on target-trial emulation and other frameworks, where we’ll explore the role and potential of observational data for evaluating the effects of interventions Don’t miss out 🔽 bit.ly/TTE_25

🚨 Next month, we’ll be hosting a one-day event on target-trial emulation and other frameworks, exploring the role and potential of observational data for evaluating the effects of interventions Open to everyone working in #datascience #biostatistics #clinicaltrials Get your ticket 🔽 bit.ly/TTE_25

Join us on 10th June (online or in London @lshtm-dash.bsky.social ) to hear from Matthew Sperrin talk about his work on 'Prediction under intervention: challenges and trade-offs'.More details at www.lshtm.ac.uk/newsevents/e...

📆 SAVE THE DATE: 26 June 📆 for our 1-day event on “Target trial emulation and other frameworks: The role and potential of observational data for evaluating effects of interventions”, hosted by the Centre for Data & Statistical Science for Health (DASH) at LSHTM. @lshtm-dash.bsky.social

Should data observed after intercurrent events handled by the hypothetical strategy be used in estimation of treatment effects? Rhian Daniel and I investigate... thestatsgeek.com/2025/04/03/t...

'G-formula with multiple imputation for causal inference with incomplete data'. Open access in Statistical Methods in Medical Research. doi.org/10.1177/0962...

📣 📣NEW PAPER providing guidance on best practice for using multiple imputation when estimating interventional mediation effects, considering missingness mechanism, multiple imputation model specification, & variance estimation #CausalSky #EpiSky Read more 👇🏽 journals.lww.com/epidem/abstr...

New paper! We extend my prior work on prognostic adjustment to work with generalized linear models. This is a nice way to gain power in randomized trials (eg with binary outcomes) by leveraging historical data in a way that does not sacrifice type I error control. arxiv.org/abs/2503.22284

Imputation of factor variables when you have partial information about some of the missing values. See here for more details thestatsgeek.com/2025/03/27/m...

3rd April, in London and online, come and hear @rlgrant.bsky.social talk about his new book with Gian Luca Di Tanna on Bayesian meta-analysis. Further details at www.lshtm.ac.uk/newsevents/e...

The EuroCIM program is live! Explore the sessions, speakers, and schedule here: www.eurocim.org/program.html. Get ready for an exciting conference! 🎉

New post on dealing with missing baseline values in randomised trials that analyse change-from-baseline open.substack.com/pub/tpmorris...

Interested in using g-methods with time-varying confounders? 💡 Advanced Confounding Adjustment (ACA) teaches inverse probability weighting, parametric g-formula, & more. 📆 June 16-20, 2025 Taught by Joy Shi, Barbra Dickerman, @miguelhernan.org. Register now: causalab.hsph.harvard.edu/courses/

It's a weird time to post about my research given ongoing events, but I'm going to share a new preprint It's my 3rd paper in a series on synthesizing statistical and mathematical models, oriented to be more of an introduction with a NHANES example arxiv.org/abs/2503.02789

What is meant by a 'while on treatment' estimand? thestatsgeek.com/2025/03/03/w...

Want to learn the fundamental principles of #ClinicalTrials?🔬 Explore key issues in design, conduct, analysis & reporting on our hybrid short course. Designed for clinical research professionals, managers & scientists. Runs 7 - 11 July 2025 Apply now✍️ bit.ly/2NldNE4

doi.org/10.1002/sim.... Our paper "A Comparison of Statistical Methods for Time-To-Event Analyses in Randomized Controlled Trials Under Non-Proportional Hazards" got published today 🎉 We describe commonly used methods, and compare their performance in a simulation study across different scenarios.

'Dealing with multiple intercurrent events using hypothetical and treatment policy strategies simultaneously' by Camila Olarte Parra, Rhian Daniel, and myself. arxiv.org/abs/2502.03329

👋Don't miss LSHTM's upcoming Virtual Open Days (11-13 Feb 2025). Join live webinars & Q&A sessions with programme directors & current students to find out what makes LSHTM a leader in #GlobalHealth education. Book your place now👉 www.lshtm.ac.uk/study/visit-...

'Estimating hypothetical estimands with causal inference and missing data estimators in a diabetes trial case study', led by Camila Olarte Parra, with Rhian Daniel and David Wright, now available open access in Biometrics: doi.org/10.1093/biom...

NOW PUBLISHED! Correction to: “Canonical causal diagrams to guide the treatment of missing data in epidemiologic studies" doi.org/10.1093/aje/... Grateful to have had the opportunity to correct our paper translating missingness DAGs (m-DAGs) into epidemiological practice #CausalSky #EpiSky

Hot off the press! 📣📣In this tutorial we illustrate available multiple imputation approaches for handling longitudinal data including when they are clustered within higher level clusters. A reproducible example with R and Stata code provided! #OpenAccess onlinelibrary.wiley.com/doi/10.1002/...

WORKSHOPS! On causal inference, missing data and SMARTs, part of the ViCBiostat Summer School (10-14 Feb, hybrid). For more details & registration visit: www.vicbiostat.org.au/short-courses #CausalSky #EpiSky

We're still seeking candidates interested in causal inference and/or survival analysis for a postdoc position in Oslo. Deadline January 31. Please apply or forward this to anyone who might be interested! www.jobbnorge.no/en/available...

"Have directed acyclic graphs fullfilled their promise?" - the recording of my debate with @margaritamb.bsky.social at the World Congress of Epidemiology 2024 is now available on YouTube! www.youtube.com/watch?v=FG79... #EpiSky #CausalSky #WCE2025

🎉 Happy New Year! 🎉 Kickstart 2025 with exciting news! 🌟 Registrations for EuroCIM 2025 are now OPEN! Secure your spot with early-bird discounts until March 1. 🔔 Reminder: Abstract submissions close January 15, 23:00 CET—don’t miss your chance to contribute!

📣Still time to apply for this job - closing date 13th January. A 5 year post doc position for a statistician with expertise in evidence synthesis / meta-analysis. Opportunity to join the excellent Bristol Evidence synthesis Appraisal and Modelling Centre at the University of Bristol, UK!

New paper led by Thomas Drury arxiv.org/abs/2412.12380

Statistical Thinking Across Borders: Building Bridges and Expanding Horizons in Clinical Biostatistics at the 46th Annual Conference of the ISCB (International Society for Clinical Biostatistics), this time in the Trinational Eurodistrict of Basel, Switzerland, from August 24th to 28th, 2025.

Hot off the preprint server: ‘Efficiency of nonparametric superiority tests based on restricted mean survival time versus the log-rank test under proportional hazards’ Short thread 👇 1/ arxiv.org/abs/2412.06442

I see renewed discussion on #statsky about the interpretation of confidence intervals. I will leave here this quote from Larry Wasserman's All of Statistics, which I love. Controlling one's lifetime proportion of studies with an interval that does not contain the parameter is surely desirable!