Thinking of performing a quantitative bias analysis for measurement error or misclassification? Then our recent software review, by Codie Wood, Kate Tilling, myself and Rachael Hughes, may be of interest: rdcu.be/eDRn2

Are estimands being correctly used? A new review of protocols led by Timothy Clark shows many incorrectly defined estimand attributes. See the top areas for improvement & full results here: trialsjournal.biomedcentral.com/articles/10.... #Trials

September @vicbiostat.bsky.social seminar: Camila Olarte Parra from @causalab.bsky.social Karolinska will speak on combining information from trial participants and non-participants in registry-based trials. All welcome online 25 September. More info: www.vicbiostat.org.au/event/combin...

We are recruiting a Research Fellow to develop machine learning based methods for handling missing data @lshtm.bsky.social. See jobs.lshtm.ac.uk/vacancy.aspx... for more details.

We are looking forward to hearing @jonathan-bartlett.bsky.social speak on the G-formula for causal inference using synthetic multiple imputation at the July @vicbiostat.bsky.social seminar! All welcome online Thursday 24th, 4:00pm Aus EST (7:00am UK time). www.vicbiostat.org.au/event/g-form...

HIRING! 2 PhD openings within the “Safe Causal Inference” consortium with experts from biostatistics, computer science, math, and epidemiology. You'll develop new methods to evaluate prediction algorithms that take the causal effect of treatments into account. 👉 www.lumc.nl/en/about-lum....

1/ NEW R PACKAGE! For estimating the impact of potential interventions on multiple mediators in countering exposure effects (led by @cttc101.bsky.social) - Paper👉 tinyurl.com/ye26jsps - Package👉 tinyurl.com/yuh4kens Thread shows published examples of how the method can be used! #EpiSky #CausalSky

📣 Calling everyone working in #datascience #biostatistics #clinicaltrials We’re bringing together experts on target-trial emulation and other frameworks, where we’ll explore the role and potential of observational data for evaluating the effects of interventions Don’t miss out 🔽 bit.ly/TTE_25

🚨 Next month, we’ll be hosting a one-day event on target-trial emulation and other frameworks, exploring the role and potential of observational data for evaluating the effects of interventions Open to everyone working in #datascience #biostatistics #clinicaltrials Get your ticket 🔽 bit.ly/TTE_25

Join us on 10th June (online or in London @lshtm-dash.bsky.social ) to hear from Matthew Sperrin talk about his work on 'Prediction under intervention: challenges and trade-offs'.More details at www.lshtm.ac.uk/newsevents/e...

📆 SAVE THE DATE: 26 June 📆 for our 1-day event on “Target trial emulation and other frameworks: The role and potential of observational data for evaluating effects of interventions”, hosted by the Centre for Data & Statistical Science for Health (DASH) at LSHTM. @lshtm-dash.bsky.social

Should data observed after intercurrent events handled by the hypothetical strategy be used in estimation of treatment effects? Rhian Daniel and I investigate... thestatsgeek.com/2025/04/03/t...

'G-formula with multiple imputation for causal inference with incomplete data'. Open access in Statistical Methods in Medical Research. doi.org/10.1177/0962...

📣 📣NEW PAPER providing guidance on best practice for using multiple imputation when estimating interventional mediation effects, considering missingness mechanism, multiple imputation model specification, & variance estimation #CausalSky #EpiSky Read more 👇🏽 journals.lww.com/epidem/abstr...

New paper! We extend my prior work on prognostic adjustment to work with generalized linear models. This is a nice way to gain power in randomized trials (eg with binary outcomes) by leveraging historical data in a way that does not sacrifice type I error control. arxiv.org/abs/2503.22284

Imputation of factor variables when you have partial information about some of the missing values. See here for more details thestatsgeek.com/2025/03/27/m...

3rd April, in London and online, come and hear @rlgrant.bsky.social talk about his new book with Gian Luca Di Tanna on Bayesian meta-analysis. Further details at www.lshtm.ac.uk/newsevents/e...

The EuroCIM program is live! Explore the sessions, speakers, and schedule here: www.eurocim.org/program.html. Get ready for an exciting conference! 🎉

New post on dealing with missing baseline values in randomised trials that analyse change-from-baseline open.substack.com/pub/tpmorris...

Interested in using g-methods with time-varying confounders? 💡 Advanced Confounding Adjustment (ACA) teaches inverse probability weighting, parametric g-formula, & more. 📆 June 16-20, 2025 Taught by Joy Shi, Barbra Dickerman, @miguelhernan.org. Register now: causalab.hsph.harvard.edu/courses/

It's a weird time to post about my research given ongoing events, but I'm going to share a new preprint It's my 3rd paper in a series on synthesizing statistical and mathematical models, oriented to be more of an introduction with a NHANES example arxiv.org/abs/2503.02789

What is meant by a 'while on treatment' estimand? thestatsgeek.com/2025/03/03/w...

Want to learn the fundamental principles of #ClinicalTrials?🔬 Explore key issues in design, conduct, analysis & reporting on our hybrid short course. Designed for clinical research professionals, managers & scientists. Runs 7 - 11 July 2025 Apply now✍️ bit.ly/2NldNE4

doi.org/10.1002/sim.... Our paper "A Comparison of Statistical Methods for Time-To-Event Analyses in Randomized Controlled Trials Under Non-Proportional Hazards" got published today 🎉 We describe commonly used methods, and compare their performance in a simulation study across different scenarios.

'Dealing with multiple intercurrent events using hypothetical and treatment policy strategies simultaneously' by Camila Olarte Parra, Rhian Daniel, and myself. arxiv.org/abs/2502.03329

👋Don't miss LSHTM's upcoming Virtual Open Days (11-13 Feb 2025). Join live webinars & Q&A sessions with programme directors & current students to find out what makes LSHTM a leader in #GlobalHealth education. Book your place now👉 www.lshtm.ac.uk/study/visit-...

'Estimating hypothetical estimands with causal inference and missing data estimators in a diabetes trial case study', led by Camila Olarte Parra, with Rhian Daniel and David Wright, now available open access in Biometrics: doi.org/10.1093/biom...

NOW PUBLISHED! Correction to: “Canonical causal diagrams to guide the treatment of missing data in epidemiologic studies" doi.org/10.1093/aje/... Grateful to have had the opportunity to correct our paper translating missingness DAGs (m-DAGs) into epidemiological practice #CausalSky #EpiSky

Hot off the press! 📣📣In this tutorial we illustrate available multiple imputation approaches for handling longitudinal data including when they are clustered within higher level clusters. A reproducible example with R and Stata code provided! #OpenAccess onlinelibrary.wiley.com/doi/10.1002/...

WORKSHOPS! On causal inference, missing data and SMARTs, part of the ViCBiostat Summer School (10-14 Feb, hybrid). For more details & registration visit: www.vicbiostat.org.au/short-courses #CausalSky #EpiSky

We're still seeking candidates interested in causal inference and/or survival analysis for a postdoc position in Oslo. Deadline January 31. Please apply or forward this to anyone who might be interested! www.jobbnorge.no/en/available...

"Have directed acyclic graphs fullfilled their promise?" - the recording of my debate with @margaritamb.bsky.social at the World Congress of Epidemiology 2024 is now available on YouTube! www.youtube.com/watch?v=FG79... #EpiSky #CausalSky #WCE2025

🎉 Happy New Year! 🎉 Kickstart 2025 with exciting news! 🌟 Registrations for EuroCIM 2025 are now OPEN! Secure your spot with early-bird discounts until March 1. 🔔 Reminder: Abstract submissions close January 15, 23:00 CET—don’t miss your chance to contribute!

📣Still time to apply for this job - closing date 13th January. A 5 year post doc position for a statistician with expertise in evidence synthesis / meta-analysis. Opportunity to join the excellent Bristol Evidence synthesis Appraisal and Modelling Centre at the University of Bristol, UK!

New paper led by Thomas Drury arxiv.org/abs/2412.12380

Statistical Thinking Across Borders: Building Bridges and Expanding Horizons in Clinical Biostatistics at the 46th Annual Conference of the ISCB (International Society for Clinical Biostatistics), this time in the Trinational Eurodistrict of Basel, Switzerland, from August 24th to 28th, 2025.

Hot off the preprint server: ‘Efficiency of nonparametric superiority tests based on restricted mean survival time versus the log-rank test under proportional hazards’ Short thread 👇 1/ arxiv.org/abs/2412.06442

I see renewed discussion on #statsky about the interpretation of confidence intervals. I will leave here this quote from Larry Wasserman's All of Statistics, which I love. Controlling one's lifetime proportion of studies with an interval that does not contain the parameter is surely desirable!

Funding available to do a PhD on statistical methods for assessing the integrity of RCTs, based in Aberdeen, with Alison Avenell, myself, Graeme MacLennan and Mark Bolland. Competitive process, funded by MRC Trials Methodology Research Partnership: www.findaphd.com/phds/project...

New paper from Shaun Seaman and me on how to simulate data from marginal structural models (MSMs) for survival outcomes, including Cox MSMs. This can be useful in simulation studies evaluating causal inference methods that use MSMs. R code provided. onlinelibrary.wiley.com/doi/10.1002/...

The European Causal Inference Meeting 2025 is coming to Ghent! ✨ Share your work with experts across the globe – abstract submission for oral & poster presentations is now open! eurocim.org/abstracts.html

10th Dec - join us in person or online for a talk by Sofia Villar from MRC BSU on 'Response-adaptive randomization in clinical trials: myth vs reality', organised by LSHTM's Data and Statistical Science for Health Centre. More details here: www.lshtm.ac.uk/newsevents/e...

Our 3 day short course @lshtm.bsky.social on multiple imputation for missing data using R is now open for registration. 17-19 June 2025. This year the course will be online only. More info here: www.lshtm.ac.uk/study/course...

Registration is now open for VicBiostat 2025 Summer School! 10-14 Feb: - Advanced causal inference - Modern missing data methods - SMARTs design & analysis All courses run hybrid in person at @Monash_SPHPM & online via Zoom: www.vicbiostat.org.au/short-courses #episky #causalinference #stats

Does the SE formula for a sample proportion assume identical 'success' probabilities? thestatsgeek.com/2024/11/04/d...

Multiple imputation with flexible parametric survival models thestatsgeek.com/2024/10/25/m...

The first webinar of the PSI/EFSPI Causal Inference special interest group will be on Tuesday 19th Nov. Speakers: Kaspar Rufibach, Susan Gruber, Florian Lasch More info here www.psiweb.org/events/event...

Comment on “Using Randomization Tests to Address Disruptions in Clinical Trials: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions”: Statistics in Biopharmaceutical Research: Vol 16 , No 4 - Get Access www.tandfonline.com/doi/full/10....

If you're looking for a spoOoOoOoky epidemiology paper for Halloween, might I recommend this one TLDR: the Kaplan-Meier estimator (with late entries) is haunted www.ncbi.nlm.nih.gov/pmc/articles...