Arnau Vich
@arnauvich.bsky.social
📤 341
📥 128
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Human gut microbiome researcher Postdoc at KU Leuven / VIB (BE) Previously UMCG (NL)
reposted by
Arnau Vich
Michael Baym
about 2 months ago
Hot off the press! Our latest paper led by
@fernpizza.bsky.social
, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
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Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
https://www.science.org/doi/10.1126/science.adx0665
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reposted by
Arnau Vich
Harris Wang
about 2 months ago
Highlighting another recent paper from the lab in Science Advances on engineering a gut probiotic to modulate GLP-1 levels and ameliorating colitis. Led by Leonie Brockmann &
@carlottaronda.bsky.social
.
@columbiasysbio.bsky.social
@columbiauniversity.bsky.social
🧬🦠💊
www.science.org/doi/full/10....
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Engineered probiotic restores GLP-1 signaling to ameliorate fiber-deficiency exacerbated colitis
Engineered probiotic delivers bacterial peptide that enhances GLP-1 and restores barrier integrity in diet-modulated colitis.
https://www.science.org/doi/full/10.1126/sciadv.adx6869
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reposted by
Arnau Vich
Eric Topol
about 2 months ago
New discovery in ulcerative colitis: a bacterial toxin that kills macrophages and increases inflammation, which could be the foundation for a new treatment
science.org/doi/10.1126/...
science.org/doi/10.1126/...
@science.org
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A bacterial toxin disarms gut defenses against inflammation
Macrophage-toxic bacteria from patients with ulcerative colitis worsen gut inflammation in mice
https://science.org/doi/10.1126/science.aec7924
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reposted by
Arnau Vich
Raes Lab
about 2 months ago
Back-to-back recognition! 💪🏼 A huge shoutout to Arnau
@arnauvich.bsky.social
and Jeroen Raes for once again making
@clarivate.com
global
#HighlyCited2025
list! 🌍✨
@viblifesciences.bsky.social
@vibmicrobes.bsky.social
clarivate.com/highly-cited...
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Clarivate Highly Cited Researchers 2025
The Highly Cited Researchers 2025 list identifies and celebrates individuals who have demonstrated significant and broad influence in their fields of research. Through rigorous selection criteria and ...
https://clarivate.com/highly-cited-researchers/
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reposted by
Arnau Vich
Daniel Figeys
2 months ago
Interested in
#drugs
,
#microbiome
and
#antibiotic
resistance, then check out our paper on the effects of over 300 drugs on the gut microbiome. Exciting results as well on the role of antibiotic resistance defining how microbiomes respond to drugs.
@quadraminstitute.bsky.social
rdcu.be/eMmcT
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Systematic metaproteomics mapping reveals functional and ecological landscapes of Ex vivo human gut microbiota responses to therapeutic drugs
Nature Communications - Here, the authors systematically map metaproteomic responses of ex vivo human gut microbiota to common therapeutics, identifying several drug classes inducing strong...
https://rdcu.be/eMmcT
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reposted by
Arnau Vich
Raes Lab
3 months ago
Another great day at
#UEGWeek
2025! 🎉Congratulations to our colleague Jorge Vazquez Castellanos for presenting his exciting work on microbial dysbiosis, inflammation, and the gut–brain axis in IBS at the United European Gastroenterology Week in Berlin🇩🇪
@myueg.bsky.social
@vibmicrobes.bsky.social
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reposted by
Arnau Vich
Raes Lab
3 months ago
Huge congratulations to our colleague
@arnauvich.bsky.social
for presenting his research on FODMAP restriction and gut microbiota in IBS patients at United European Gastroenterology Week 2025 in Berlin🇩🇪👏!
#UEGWeek
@myueg.bsky.social
@vibmicrobes.bsky.social
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reposted by
Arnau Vich
Eric Topol
5 months ago
The most interesting report of the week (IMHO) 🧵
add a skeleton here at some point
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reposted by
Arnau Vich
Eric Topol
5 months ago
www.nature.com/articles/d41...
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New hope for Alzheimer’s: lithium supplement reverses memory loss in mice
Studies in rodents and humans suggest that low levels of the metal contribute to cognitive decline.
https://www.nature.com/articles/d41586-025-02471-4
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reposted by
Arnau Vich
Cristina Legido-Quigley
6 months ago
Super happy to share our latest preprint in
#liverdisease
&
#gut
microbiota mechanisms.
www.medrxiv.org/content/10.1...
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Alcohol-related liver disease disrupts bile acid synthesis and is associated with compensatory gut microbiota changes
Background: Alcohol overuse disrupts liver function and alters microbial gut communities, with alcohol-related liver disease (ALD) accounting for half of all liver-related deaths worldwide. Bile acids...
https://www.medrxiv.org/content/10.1101/2025.07.23.25332046v1
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Arnau Vich
Sergio Andreu-Sanchez
8 months ago
Thrilled to share that our manuscript on strain-level gut microbiome variation across diverse populations and human phenotypes is out today in
@cellpress.bsky.social
Curious about how strain diversity relates to human traits? Follow this thread! 🌍 (1/n)
www.sciencedirect.com/science/arti...
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Global genetic structure of human gut microbiome species is related to geographic location and host health
The human gut harbors thousands of microbial species, each exhibiting significant inter-individual genetic variability. Although many studies have ass…
https://www.sciencedirect.com/science/article/pii/S0092867425004167
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reposted by
Arnau Vich
Oliver Schwengers
10 months ago
🦠🧬🖥️ New Bakta DB v6.0 released! After a year, it was time for a Bakta database update - and it's a huge one: - IPS: 330.9M - PSC: 135.3M - PSCC: 37M
doi.org/10.5281/zeno...
👇 1/6
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Bakta database
This data repository contains the mandatory DB for Bakta. It is available in two versions: the default (db.tar.gz or) and a lightweight alternative (db-light.tar.gz). Bakta is a tool for the rapid & s...
https://doi.org/10.5281/zenodo.14916843
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reposted by
Arnau Vich
Seth Bordenstein
10 months ago
Citation:
www.sciencedirect.com/science/arti...
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A designed synthetic microbiota provides insight to community function in Clostridioides difficile resistance
Clostridioides difficile, a major cause of antibiotic-associated diarrhea, is suppressed by the gut microbiome, but the precise mechanisms are not ful…
https://www.sciencedirect.com/science/article/pii/S1931312825000551?via%3Dihub
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reposted by
Arnau Vich
Nature
10 months ago
Nature research paper: Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses
https://go.nature.com/3XmyOPD
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Macrophages recycle phagocytosed bacteria to fuel immunometabolic responses - Nature
Phagocytosed bacteria can serve as an alternative nutrient source for macrophages, influencing their metabolic and immune responses through the recycling of microbial components, with the process regulated by nutrient-sensing mechanisms and bacterial viability.
https://go.nature.com/3XmyOPD
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reposted by
Arnau Vich
Michael Baym
11 months ago
Legitmately thrilled to share our latest work, in which
@fernpizza.bsky.social
solved an experimental challenge in plasmid biology as old as the field: measuring how plasmids compete and evolve within individual cells!
add a skeleton here at some point
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reposted by
Arnau Vich
Nature Microbiology
11 months ago
A must-read for any microbiome researcher 🦠📐and a new addition to our
#bestpractices
series Planning and describing a microbiome data analysis by
@amydwillis.bsky.social
and
@davidandacat.bsky.social
www.nature.com/articles/s41...
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Planning and describing a microbiome data analysis - Nature Microbiology
We provide guidance on the planning, execution and description of statistical analyses in microbiome studies.
https://www.nature.com/articles/s41564-025-01944-6?utm_source=bluesky&utm_medium=social&utm_campaign=nmicrobiol
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reposted by
Arnau Vich
Raes Lab
11 months ago
We're hiring a postdoc!🚨 Study human-associated microbial communities in health & disease. 🔬Requirements: - PhD in bioinformatics, microbiology, or related field - Expertise in omics - Strong publication record Apply now!🌟
jobs.vib.be/j/69697/post...
@vibmicrobes.bsky.social
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Postdoctoral position in bioinformatics of the human gut microbiome - VIB
About the Lab Thelab of JeroenRaes(VIB, KU Leuven) is home to a vibrant, dynamic and international group of researchers in the field of gut microbial ecology and its clinical applications
https://jobs.vib.be/j/69697/postdoctoral-position-in-bioinformatics-of-the-human-gut-microbiome
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reposted by
Arnau Vich
Levi Waldron
11 months ago
Excited to share our MicrobiomeBenchmarkData preprint, addressing compositional data analysis for microbiome DA. This Bioconductor package features 3 datasets with biological ground truths. Spoiler: simple methods like LEfSe, Wilcoxon, RNA-seq methods performed well
www.biorxiv.org/content/10.1...
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Commonly used compositional data analysis implementations are not advantageous in microbial differential abundance analyses benchmarked against biological ground truth
Previous benchmarking of differential abundance (DA) analysis methods in microbiome studies have employed synthetic data, simulations, and "real data" examples, but to the best of our knowledge, none ...
https://www.biorxiv.org/content/10.1101/2025.02.13.638109v1
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reposted by
Arnau Vich
Raes Lab
about 1 year ago
A big congratulations to our incredible team at RaesLab! We’re excited to share that two of our colleagues, Arnau
@arnauvich.bsky.social
and Jeroen, have been honored on the global
#HighlyCited2024
researchers list by @Clarivate🤩🙌🏼
@viblifesciences.bsky.social
clarivate.com/highly-cited...
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Highly Cited Researchers | Clarivate
The Highly Cited Researchers 2024 list identifies and celebrates individuals who have demonstrated significant and broad influence in their fields of research. Through rigorous selection criteria and ...
https://clarivate.com/highly-cited-researchers/
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Although I'm not a big fan of individual recognitions in science- collaboration and teamwork are the real driving forces- I'm honored to be recognised as
#HighlyCited2024
by Clarivate. Grateful to all colleagues, mentors and collaborators who made this happen.
about 1 year ago
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