Excited to share our latest paper - now out in @science.org - we showed how oxytocin modulates maternally-directed behavior in young mice (P15).

Proposal recommended for funding! Which means we have a fresh, 3-year-funded position available for a computational postdoc interested in studying dynamics of social interactions in rats, with simultaneous Neuropixels data to follow 🐀🐀🐀 Proper job ad pending, but email me if interested!

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵 www.nature.com/articles/s41...

The firing of neural populations is high-dim even if their subthreshold activity is low-dim! This work by @bio-emergent.bsky.social and @haydari.bsky.social shows how, with a solvable model, a data analysis technique, and data from mouse visual cortex: www.biorxiv.org/content/10.1...

Excited to share our Science paper on HaloDA1.0-the first genetically encoded far-red dopamine sensor! 🥳It enables powerful multiplex imaging in neurons, brain slices, and live animals.🧠🔬 #GRABsensors #Dopamine www.science.org/doi/10.1126/...

Excited to share that the astrocyte-centered half of my thesis work is now out @science.org ! With @mishaahrens.bsky.social and @marcduque.bsky.social science.org/doi/10.1126/... 1/8

Thrilled to share our work in ScienceAdvances: “Chronic ethanol exposure produces sex-dependent impairments in value computations in the striatum.” Huge thanks to Tricia @janaklab.bsky.social, Daeyeol @ungteoriz.bsky.social, Angela, and my friend Robin! www.science.org/doi/full/10....

Many of us use 2p scopes to image 3D volumes of brain. But then we analyze the data plane by plane, resulting in duplicated neurons, missed neurons, and low s/n. Let's go 3D! Suite3D: Volumetric cell detection for two-photon microscopy by @haydari.bsky.social & team. www.biorxiv.org/content/10.1...

(1/n) Why is it so hard to stop eating when something tastes amazing? Our new @ science.org paper reveals that dopamine helps sustain our drive for tasty treats—and may explain how anti-obesity Ozempic tames those urges. doi.org/10.1126/science.adt0773

New @science.org Hedonic eating (eating for pleasure, not need) is mediated by dopamine neurons (in the brain ventral segmental area, VTA) and they are antagonized by GLP-1 drugs, such as semaglutide, leading to weight loss www.science.org/doi/10.1126/...

Our paper from Junchol Park and collaborators that has been brewing for a while. Trying to capture our thinking about what action specification in striatum means and what would constitute evidence for such a model. Longer thread soon, but it’s online now. www.cell.com/neuron/fullt...

HCN1 channels in GABAergic amygdalar neurons underpin male-biased aggressive behaviors https://www.biorxiv.org/content/10.1101/2024.12.07.627305v1