This is for the real lovers of esoterica RSTT: Work-in-progress set-theoretic type algebra for the R language by Mickaël Laurent #RStats, #OCaml, #C API, Programming language theory and set theory repo : github.com/E-Sh4rk/rstt/ with a REPL !

My day job is to conduct statistical analysis of omics data, and most of it is spent writing R. In this new blog post, I share the R package shape I reached for in my recent projects. mickael.canouil.fr/posts/2026-0... #RStats #Shiny #Quarto #OpenSource #DataScience

since i am doing lot of pi based vibesloping these days and R markdown is my testing framework, made piknit #RStats package with Slope Code for a coming work github.com/sounkou-bioi...

cited Marx one time in a session, and now Slope Code autocompletes "idealist" at each new concepts "discovery". Below i suggest let's see what are the lazy eval/effect type of libraries in the Typescript (for my own culture) world just like in #RStats : --->Idealist

‼️Big package update on CRAN! #raymolecule v0.9.0 brings ribbon diagrams! Grab PDB files directly from the RCSB Protein Data Bank with just their PDB ID and render it in #RStats with #rayrender or #rayvertex: it's that easy! read_pdb("2w5o") |> generate_ribbon_scene() |> render_model()

Now you can use your Claude or ChatGPT subscription to run the R agent harness, corteza. No API key, no per-token meter, and it's on CRAN! Thanks to @hadley.nz for the provider-native search idea, and to @pp0196.bsky.social, whose Codex OAuth PR became tinyoauth. cornball.ai/posts/claude...

New release of secretbase 1.3.0 - a cryptography and data encoding toolkit. Adds base64 URL-safe variants. This is in addition to sha256, sha3, shake256, keccak, siphash, base58, cbor, json etc. all in 40kB. This package provides secure hashing for {targets}. #Rstats github.com/shikokuchuo/...

#Rstats package update: zip 3.0.0 with some very cool new things: password protected zip files, vectorized and concurrent unzip(), unzip over HTTP, progress bars. Full change log at github.com/r-lib/zip/re...

I’m excited to announce that #codex is now available (typically through a chatGPT subscription) from R through corteza. Logging in is enabled by the dev version of the new tinyoauth package, already in the CRAN queue! A big thank you to @pp0196.bsky.social for the contribution.

Beware #Rstats users, according to Misanthropic, an R to C transpiler is a security risk 😄 Fable turned out to as expected to be La Fable I think some french speaker at Misanthropic is doing some kind of joke with these model names

Rbebelm: #RStats Bindings for 'BebeLM' 'CPU' Inference For A 8B-1B Active model, not that bad A tiny R CLI "Agent" inspired by Corteza github.com/cornball-ai/... repo: github.com/sounkou-bioi... Upstream Rust crate : github.com/maximecb/beb... LFM2.5-8B-A1B blog: www.liquid.ai/blog/lfm2-5-...

Ropendal: Abstract Filesystem access in #Rstats via 'Apache OpenDAL' R/Rust package using #savvy and exporting a C API because i for whatever reason i frequently download terabytes from Google Drive. Async API is heavily by #nanonext. Several time faster than paws for most ops at MinIO baseline

RsimdDispatch: Runtime 'SIMD' Dispatch Templates for 'C' Code in #RStats Packages hellorust.multiversion: Minimal Rust SIMD Multiversioning Example for #RStats A way to enjoy both Linux binary Packages and Optimized code at runtime. github.com/sounkou-bioi... github.com/sounkou-bioi...

Our medRxiv preprint is out: Automated versus manual reanalysis in rare disease genomics. We reanalysed 377 rare disease cases from a routine diagnostic genome sequencing cohort, comparing the established manual workflow with Talos-based automation. www.medrxiv.org/content/10.6...

We conducted the most extensive systematic GWAS gene prioritisation to date across all openly available data, with a retrospective analysis of 100,526 GWAS over the past decade: www.biorxiv.org/content/10.6...

Rducks: Register arbitrary #Rstats User-Defined Functions in duckdb-r (1.5.2) including (sacrilege) distributed chunk execution mode via #mirai+libnng. Arrow C Data marshaling dance that that may be removed later. Trivial #duckplyr integration. Stream DuckDB queries repo: github.com/sounkou-bioi...

#duckplyr with no fallbacks, because why not Learned that prefixing a function call with `dd$` is a way to call arbitrary duckdb functions (in our case a registered #RStats UDF) duckplyr.tidyverse.org/dev/articles...

@hannes.muehleisen.org are their plans to expose the (de) serialization primitives used in quack in the next C (unstable) stable API? Wld allow some (ridiculous) applications like the multiprocess/distributed #RStats scalar UDF execution mode via arrow IPC i am using here github.com/sounkou-bioi...

It is with great sadness that we announce the passing on 1 April of Tomáš Kalibera, a valuable member of the R Core Team for close to 10 years, after a short but aggressive illness. Tomáš is survived by his wife and 1 year old son. A full obituary will be posted in due time.

Use Claude code to fix some ci yaml crap or other minor issue and all of the sudden the LLM is a "contributor" on your repo, anthroslopic and the weird misanthropic co-author default

Some performance tuning (row batching size, schema sharing, streaming) get the ducknng arrow IPC to 30% slower than quack_query at 10 Million rows, our own adaptation of the DuckDB internal application/vnd.duckdb serializer is 20% faster than quack_query ! Even faster over tcp #nng #DuckDB #quack

Reproduction of the drogonR benchmark after addition of additional #RStats http frameworks No-op setup (adding some actual work should be fairer to plumber2-mirai) drogonR 10x>> nanonext 2x> RestRServe 10x>> httpuv/plumber(2) Vibecoded repo for issues with the setup github.com/sounkou-bioi...

drogonR: High-performance HTTP server for #RStats, powered by the Drogon C++ framework by Yuri Baramykov Order of magnitude faster than httpuv/plumber with SSE support out of the box github.com/Zabis13/drog... #Network

ggmlR: #Rstats bindinds to 'GGML' Tensor Operations for Machine Learning by Yuri Baramykov github.com/Zabis13/ggmlR #DeepLearning

Release of version 0.1.1 of the duckdb community extension ducknng: a nanonext inspired DuckDB C extension providing binding to the NNG scalability protocols and a Arrow IPC RPC based Framework Call into any NNG (or http) speaking runtime. What better example than calling a nanonext #RStats server

Watch me ramble about #rstats in an attempt to introduce my "builder" preprocessor. Word count: - "heh" - 56 - "ah" - 47 - "hmmm" - 34 - "..." - 23 - *inaudible - 17 youtu.be/VBj6Q8Ad6aU?...

Async R gets a proper memory model. mirai 2.7.0 and mori 0.2.0 on CRAN: - byte-level dispatcher queue cap: `daemons(memory = ...)` - non-blocking submit on a full queue: `try_mirai()` - mori out of experimental – zero-copy shared memory across processes opensource.posit.co/blog/2026-05... #rstats

We are pleased to announce that Mikael Jagan has joined the R Core Team. #RStats He has been an active contributor to the R project for several years, proposing bug fixes and enhancements. Further, he has been co-authoring/maintaining the important Matrix package and more recently lme4 and glmmTMB.

After seeig some recent commits on the #Rstats source tree around R_TailCall github.com/r-devel/r-sv... , this post from stackoverflow was quite interesting to read #esoterica stackoverflow.com/questions/78...

Quick #r2u update for #Rstats on #Ubuntu: - R 4.6.0 available on all three LTS releases ✅ - BioConductor 3.23 available on all three LTS releases ✅ - Ubuntu 26.04 support available for arm64 and amd64 ✅ #r2u. Fast. Easy. Reliable. Pick all three. eddelbuettel.github.io/r2u/

#RStats package s7contract: 'Go'-Like Interfaces and 'Rust'-Like Traits with 'S7' with progressive runtime type checks opt-in github.com/sounkou-bioi...

the project (of dubious usefulness ) of a DuckDB extension for arbitrary #RStats UDFs for #DuckDB's R client is taking shape, with some optimizations only for the fun of it. Totally thread unsafe for now since queuing tasks of Duckdb worker threads to be executed on the R main thread is dubious

Prompted by this post and the fact that Go-Like Interfaces and S7 where something on my mind for a long time, so i prompted a (sycophantic) LLM to implement a slow Go-Like interfaces on top of S7 (zero type safety, but this can be corrected with) + rust like trait system github.com/sounkou-bioi...

#RStats Playable Doom! Figured out some key handling stuff in my custom graphics device, so I can now actually control the game! Content Warning: I'm not good at doom :)

For segfault lovers #CRAN Release of Rtinycc v0.1.8 For 'C' Scripting in #RStats Binding to libctcc and a declarative C FFI framework including thread safe R callbacks in C Code The package remove the R2C code transformation work to a coming downstream work github.com/sounkou-bioi...

Very nice post about why you may want your AI / LLM coding session running from inside your #Rstats session. With, as so often with posts by @troyhernandez.bsky.social, a calm and reasoned argument why the tinyverse is so applicable here too.

#duckdnng, a shameless #DuckDB extension which is LLM enabled copy pasta of the excellent handcrafted #Rstats #nanonext C code and API design

I was very happy that i managed to get to compile htslib for the #webr environment and the duckhts bundle in the #RStats package, but then i see that i incorrectly assumed that the #DuckDB platform was wasm_mvp, it is Linux_i686_musl instead

#Bioinformatics #Nextflow #RStats Mostly vibecoded Nextflow R plugin nanoarrow on R side, Arrow in JVM/Groovy side github.com/sounkou-bioi...

Read, discuss, think deeply, and prepare to vote later this week.

Preprint #1: Intrinsic dataset features drive mutational effect prediction by protein language models www.biorxiv.org/content/10.6... @clauswilke.com

Microbial communities can harbor many species that do not coexist in pairs, yet can coexist in the full community. Here we provide the mathematical foundations of emergent coexistence, and explain why it can't be predicted from pairwise tests journals.plos.org/ploscompbiol...

hmmm #Rust #Bioinformatics "rewrites" with #LLMs (looks like the promotional tool is propaganda when comparison is against a not particularly optimized python tools) rewrites.bio

#Ducktinycc 'C' scripting in #Duckdb via #TinyCC Of course what better example than the embedded #RStats example from "Writing R extensions". With a bit more work (and threading issue stuff) this can be extended into some arbitrary R UDFs API for the r-duckdb Repo: github.com/sounkou-bioi...

#RStats #Rduckhts version 1.1.4-0.0.1 released On CRAN Besides hts format I/0, some sequence UDFs and a port of BCFtools score, liftover and munge plugins to run using #DuckDB for post-GWAS ops The R-agnostic #Duckdb community extension update on its way too A funny thing in the ports, floats !

Built a small experiment to render plots inline inside the #rstats console using terminal graphics. It's basically taking a nativeRaster and displaying it directly in the terminal (Sixel / Kitty / etc.). For reference, similar ideas already exist in packages like terminalgraphics and rsixel.

29 years of #rstats community knowledge was sitting in hard-to-search pipermail archives. So I built a more modern home for it. Introducing the R Mailing List Archives: 631,000+ messages from 32 lists, fully searchable and available as open data. r-mailing-lists.thecoatlessprofessor.com

Stop building systems for agents, build systems for human. We need infrastructures to help us holding accountability of agent's code. blog.xiangpeng.systems/posts/stop-b...