Brian DePasquale
@briandepasquale.bsky.social
📤 1561
📥 391
📝 43
science.
https://briandepasquale.github.io
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Brian DePasquale
samuel mehr
about 16 hours ago
"the quickest way to get a collaborator to return edits on your manuscript is to write down their affiliation wrong" (ancient academic proverb)
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Ahmed El Hady
20 days ago
Can one bring together Reinforcement learning and Drift Diffusion models to understand collective foraging ? Congrads to Jonathan Marienhagen , Lisa Blum Moyse and Dominik Deffner on this new study. Very happy that I was part of this collaboration. Preprint here:
osf.io/preprints/ps...
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Brian DePasquale
New papers in Network Science
about 2 months ago
PLOS Comput. Biol.: Stochastic activity in low-rank recurrent neural networks
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1013371
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Brian DePasquale
Dan Levenstein
about 2 months ago
“NeuroAI should not remain limited to learning statistical relationships, but should also help in building mechanistic and causal models of neural activity. These models will incorporate biological properties of neural circuits, including cellular characteristics and network properties.” 💯💯💯
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Brian DePasquale
Meg Younger
2 months ago
New preprint from
@darbly.bsky.social
@briandepasquale.bsky.social
and my labs! If you love (or hate) mosquitoes, have a look:
doi.org/10.1101/2025...
We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟
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Recurrent connectivity supports carbon dioxide sensitivity in Aedes aegypti mosquitoes
The mosquito Aedes aegypti′s human host-seeking behavior depends on the integration of multiple sensory cues. One of these cues, carbon dioxide (CO2), gates odorant and heat pathways and activates hos...
https://doi.org/10.1101/2025.07.29.667487
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Brian DePasquale
John Tuthill
4 months ago
Congrats to the 2025 cohort of McKnight Scholars!
www.mcknight.org/news-ideas/2...
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Brian DePasquale
Lucia Prieto Godino
4 months ago
How do brain circuits evolve? We started looking for some answers by using synapse-resolution cross-species comparative connectomics on an entire olfactory circuit 👇
bit.ly/44aVm9E
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Brian DePasquale
PLOS Biology
4 months ago
Can
#AI
become a true scientist?
@ninamiolane.bsky.social
explores how new technologies are reshaping scientific discovery, and why human expertise remains essential as we enter a new era of research powered by intelligent algorithms. 🧪
plos.io/4kZi0aB
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The fifth era of science: Artificial scientific intelligence
Can AI become a true scientist? This Perspective explores how new technologies are reshaping scientific discovery, and why human expertise remains essential as we enter a new era of research powered b...
https://plos.io/4kZi0aB
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Tired of your boring old DDM? Check out recent work by grad student
@ryguy.io
that introduces a *state-dependent* DDM using an underlying HMM. We find mice change their speed-accuracy strategy from trial to trial! Code provided! (in Julia of course!)
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4 months ago
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Brian DePasquale
Itai Yanai
4 months ago
90% of doing science is being open to new ideas.
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Nico Adams
4 months ago
Unsurprising, but nevertheless tragic. Makes it very hard for integrators and multidisciplinarians to exist in academia.
#academicsky
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Athena Akrami
5 months ago
Hivemind, what's the best approach/tool to aggregate neural data across sessions (and animals) in dimensionality reduction analyses, particularly when it's not known how overlapping the pool of neurons are over different sessions?
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Brian DePasquale
Richard Sever
5 months ago
"The core strategy is to slow NIH spending to generate surpluses...then use surpluses as justification for slashing the budget...unspent [$] won’t be because NIH doesn’t have good science to spend on [but] because the administration has blocked spending"
donmoynihan.substack.com/p/the-nih-bu...
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https://donmoynihan.substack.com/p/the-nih-budget-is-on-a-fast-track
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Brian DePasquale
Blake Richards
5 months ago
Using pretrained vision-language models to align neural signals from different modalities:
arxiv.org/pdf/2407.14020
Cool stuff, though I would still love to see if we could align different neural modalities without the pretrained VLMs... 🧠📈 🧪
#NeuroAI
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https://arxiv.org/pdf/2407.14020
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Brian DePasquale
Peter Sokol-Hessner
5 months ago
“Science is a smart, low cost investment. The costs of not investing in it are higher than the risk of doing so… talk to people about science.” -
@kevinochsner.bsky.social
makes his case to the field
#sans2025
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Brian DePasquale
Nicole Rust
6 months ago
First big new
@simonsfoundation.org
neuroscience collaboration launches - exciting!! The product of a HUGE competition among the best minds and teams. Congrats to this group:
www.simonsfoundation.org/neuroscience...
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Simons Collaboration on Ecological Neuroscience
The mission of the Simons Collaboration on Ecological NEuroscience (SCENE) is to understand how affordances offered by the world shape representations in the mind and the brain.
https://www.simonsfoundation.org/neuroscience/simons-collaboration-on-ecological-neuroscience/?utm_source=Simons+Foundation&utm_campaign=1110398be2-NEURO_SCENE_LAUNCH_2025&utm_medium=email&utm_term=0_-1110398be2-746269779
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Brian DePasquale
The Transmitter
6 months ago
Olfactory neuroscientists have known for a while that their stimuli stink. A new analysis illuminates the extent of the problem. By
@callimcflurry.bsky.social
#neuroskyence
www.thetransmitter.org/olfaction/sm...
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Smell studies often use unnaturally high odor concentrations, analysis reveals
It’s time to fashion olfactory neuroscience stimuli based on odor concentrations in the wild, say study investigators Elizabeth Hong and Matt Wachowiak.
https://www.thetransmitter.org/olfaction/smell-studies-often-use-unnaturally-high-odor-concentrations-analysis-reveals/?utm_source=bluesky&utm_medium=org-social&utm_campaign=20250416-unnatural-high-odor-concentration
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Brian DePasquale
Harrison Ritz
6 months ago
Cool project led by Victor Geadah, fitting smoothly time-varying (and condition-varying) linear dynamical systems to neural activity.
arxiv.org/abs/2502.18347
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Brian DePasquale
Venki Murthy
6 months ago
I feel compelled to acknowledge the dread and dismay that many international students in the US are feeling at the moment - we see you, even if we feel rather powerless for now. Here's the very first visa stamp on my Indian passport ~40 years ago to come to UW Seattle for an MS in Bioengineering.
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David Lipshutz
6 months ago
📣 Grad students and postdocs in computational and theoretical neuroscience: please consider applying for the 2025 Flatiron Institute Junior Theoretical Neuroscience Workshop! All expenses are covered. Apply by April 14.
jtnworkshop2025.flatironinstitute.org
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Brian DePasquale
Nima Dehghani
6 months ago
@petersenpeter.bsky.social
@jakhmack.bsky.social
@sejdevries.bsky.social
@bingbrunton.bsky.social
@jeremymagland.bsky.social
@briandepasquale.bsky.social
@maryamshanechi.bsky.social
+others not on sky: David Kleinfeld , Tim Gardner, Maryam Shanechi, Carlos Ponce, Eli Schlizerman, Edgar Walker,...
add a skeleton here at some point
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Brian DePasquale
Ida Bae Wells
6 months ago
Can we get more of this? “The Japanese American National Museum will ‘scrub nothing,’ Fujioka said, and instead will highlight the importance of DEI. “Our community is based on diversity, equity is guaranteed to us in the Constitution, and inclusion is what we believe in,” Fujioka said.
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Japanese American National Museum takes a stand against DOGE cuts to NEH
The National Endowment for the Humanities warned museums across the country that it was slashing funding, including money previously pledged to places such as LACMA and the Japanese American National ...
https://www.latimes.com/entertainment-arts/story/2025-04-04/national-endowment-humanities-neh-doge-trump-funding-cuts-museums
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Brian DePasquale
Lee Sweetlove
6 months ago
Lots of excellent advice in this piece. The core message - only through writing do you really think and order your thoughts into logical sense. Makes a case for not using AI for 1st draft because you bypass the thinking step
www.nature.com/articles/s41...
@naturebiotech.bsky.social
#PlantScience
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An open letter to graduate students and other procrastinators: it’s time to write - Nature Biotechnology
Nature Biotechnology - An open letter to graduate students and other procrastinators: it’s time to write
https://www.nature.com/articles/s41587-025-02584-1
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Got for it! But be warned — I’m sensitive to initial conditions!
add a skeleton here at some point
6 months ago
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Brian DePasquale
Jenelle Feather
6 months ago
Already feeling
#cosyne2025
withdrawal? Apply to the Flatiron Institute Junior Theoretical Neuroscience Workshop! Applications due April 14th
jtnworkshop2025.flatironinstitute.org
add a skeleton here at some point
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#cosyne2025
GNN workshop w/
@neurokim.bsky.social
was a huge success! For those looking to stay in touch, see GitHub repo for workshop docs, including our tutorial
github.com/depasquale-l...
!
6 months ago
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Brian DePasquale
Russ Poldrack
6 months ago
This is an utterly amazing paper.
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On the Biology of a Large Language Model
We investigate the internal mechanisms used by Claude 3.5 Haiku — Anthropic's lightweight production model — in a variety of contexts, using our circuit tracing methodology.
https://transformer-circuits.pub/2025/attribution-graphs/biology.html
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Brian DePasquale
Zinn Education Project
6 months ago
"I contend what you are doing is against the rights I have as a citizen of this country."
#tdih
1944 Frank S. Emi interrogated when he refused WWII draft while imprisoned (Exec. Order 9066) as a Japanese American by US gov't. Convicted of conspiracy. Read ⬇️
www.zinnedproject.org/news/tdih/fr...
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March 31, 1944: Frank S. Emi Interrogated
Frank S. Emi protested the draft during Japanese American incarceration and was interrogated.
https://www.zinnedproject.org/news/tdih/frank-s-emi-interrogated/
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@cosynemeeting.bsky.social
Also! Don’t miss a 💡 insightful tutorial on GNNs for connectomics analysis tomorrow at the workshop! Details here:
sites.google.com/bu.edu/gnnwo...
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gnnworkshop cosyne2025
It's All Connected!
https://sites.google.com/bu.edu/gnnworkshop-cosyne2025/home
6 months ago
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@cosynemeeting.bsky.social
#wheresmikelong
6 months ago
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Rounding out our speakers
@cosynemeeting.bsky.social
GNN workshop is
@dom-beaini.bsky.social
of
@mila-quebec.bsky.social
and
@valenceai.bsky.social
. Come hear him tell us how to learn a…MOLECULE! Don’t forget brains 🧠 are made of chemicals ⚗️ and chemicals + graphs = 🫶
6 months ago
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More 🔥🔥 speakers at
@cosynemeeting.bsky.social
GNN workshop:
@ninamiolane.bsky.social
who runs the
@geometric-intel.bsky.social
lab at UCSB. She will take us beyond 🚀🚀 GNNs, presenting a survey of message passing topological neural networks for neuroscience
6 months ago
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@cosynemeeting.bsky.social
workshops are almost here! Join GNN workshop w
@neurokim.bsky.social
and Sam Lewallen to hear
@herrsaalfeld.bsky.social
head of computation
@hhmijanelia.bsky.social
present on GNNs for learning structure and function underlying neural assemblies
#cosyne2025
6 months ago
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T-3 days to
#cosyne2025
GNN workshop! Join us to hear Gal Mishne of UCSD talk about graph based methods for learning dynamic functional connectivity. Gal has done a TON of great foundational work on graph based approaches to data analysis in neuroscience — not to be missed!
6 months ago
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Brian DePasquale
Nina Miolane
6 months ago
At
@cosynemeeting.bsky.social
? Don't miss the workshop "It's All Connected" or how graph neural networks help us understand the structure-function relationship in the brain🧠 Thanks to the organizers
@neurokim.bsky.social
@briandepasquale.bsky.social
Sam Lewallen 🌟
sites.google.com/bu.edu/gnnwo...
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gnnworkshop cosyne2025
It's All Connected!
https://sites.google.com/bu.edu/gnnworkshop-cosyne2025/home
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Brian DePasquale
Kristin Branson
6 months ago
Excited to participate in the Graph Neural Networks workshop at Cosyne on Monday March 31 (day 1): IT’S ALL CONNECTED! Graph approaches to geometric complexity in neuroscience
sites.google.com/bu.edu/gnnwo...
Hope to see you there!
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gnnworkshop cosyne2025
It's All Connected!
https://sites.google.com/bu.edu/gnnworkshop-cosyne2025/home
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Brian DePasquale
Allen Institute
6 months ago
You're invited to the livestream of our Neurobiology in Changing Environments symposium! Listen to experts in the emerging field of nervous system function and resilience in a changing world, incl.
@adc-neuroenv.bsky.social
scientists. Register to get the link:
alleninstitute.org/events/2025-...
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Feeling excited about
#cosyne2025
? Save some energy for
@cosynemeeting.bsky.social
GNN workshop! Quan Do from BU will present work illustrating how GNNs can be used to solve challenging puzzles (try them!
www.nytimes.com/interactive/...
) giving insight into human reasoning!
6 months ago
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@cosynemeeting.bsky.social
GNN workshop speaker profile 3 is Ashok Litwin-Kumar, of
@columbiauniversity.bsky.social
! Ashok has been a driving force in connectomics-based modeling.
7 months ago
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Brian DePasquale
Laura Driscoll
7 months ago
After hearing about the ongoing hotel workers strike at the
#COSYNE2025
hotel, I cancelled my reservation and booked a room at a hotel a short 10 minute walk from the meeting. It was easy and I encourage others to do the same!
#solidarity
montreal.citynews.ca/2025/01/14/q...
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Montreal’s Queen Elizabeth Hotel reopens after temporarily closing during holidays due to labour dispute
The Fairmont Queen Elizabeth Hotel in Montreal has reopened after temporarily closing due to an ongoing labour dispute. Quebec’s largest hotel made the announcement on Dec. 12 and shut their doors day...
https://montreal.citynews.ca/2025/01/14/queen-elizabeth-hotel-reopens-ongoing-strike/
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Brian DePasquale
Sam Wang
7 months ago
"I'm the Secretary of State...brought to you by Carl's Jr."
www.youtube.com/watch?v=1BYF...
add a skeleton here at some point
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Just over a week to
#cosyne2025
workshops! Speaker profile number 2 for GNN workshop w/
@neurokim.bsky.social
and Sam Lewallen is
@kristinmbranson.bsky.social
of
@hhmijanelia.bsky.social
! Kristin’s lab develops cutting edge machine vision approaches for quantitatively studying animal behavior.
7 months ago
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Brian DePasquale
Kim Stachenfeld, PhD
7 months ago
Want to procedurally generate large-scale relational reasoning experiments in natural language, to study human psychology 🧠 or eval LLMs 🤖? We have a tool for you! Our latest
#ICLR
work on long-context/relational reasoning evaluation for LLMs ReCogLab!
github.com/google-deepm...
Thread ⬇️
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Brian DePasquale
Grace Lindsay
7 months ago
From my PhD advisor
@kenmiller.bsky.social
at Columbia. These are the grants that funded my PhD.
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Countdown to
#COSYNE2025
! Leading up to
@cosynemeeting.bsky.social
GNN workshop w
@neurokim.bsky.social
and Sam, allow us to introduce our fabulous speakers, starting with
@wesleyqian.bsky.social
! Wesley is part of
osmo.ai
foundling team, using GNNs to digitize smell!
7 months ago
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Brian DePasquale
The Transmitter
7 months ago
The bill, which was approved today by the U.S. House of Representatives and heads next to a Senate vote, includes 20 percent less BRAIN Initiative funding than last year. By
@avaskham.bsky.social
www.thetransmitter.org/funding/u-s-...
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U.S. BRAIN Initiative set to lose $81 million this year
A government spending bill, approved today by the House of Representatives, allocates 20 percent less funding for the program than last year.
https://www.thetransmitter.org/funding/u-s-brain-initiative-set-to-lose-81-million-this-year?utm_source=bsky&&utm_campaign=20250311-brain-initiative-breaking-news
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Brian DePasquale
Kevin K. Yang 楊凱筌
7 months ago
Fine-tune protein language models to predict protein symmetry
@erichorvitz.bsky.social
www.nature.com/articles/s41...
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Brian DePasquale
Avery HW Ryoo
7 months ago
How can large-scale models + datasets revolutionize neuroscience 🧠🤖🌐? We are excited to announce our workshop: “Building a foundation model for the brain: datasets, theory, and models” at
@cosynemeeting.bsky.social
#COSYNE2025
. Join us in Mont-Tremblant, Canada from March 31 – April 1!
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Brian DePasquale
Ann Kennedy
7 months ago
Hello friends! Applications for the CSHL course on Neural Data Science are now open- I will be lecturing and hanging out at the course for a few days this July.
meetings.cshl.edu/courses.aspx...
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Neural Data Science
Cold Spring Harbor Laboratory Meetings & Courses -- a private, non-profit institution with research programs in cancer, neuroscience, plant biology, genomics, bioinformatics.
https://meetings.cshl.edu/courses.aspx?course=C-NEUDATA
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