On my way to # www.grc.org/meiosis-conf... cruising 10 km in the air with a stable (and free) WIFI connection. Who knew such things were possible?!

Before CRISPR there was VIPR

The best thing since *before* sliced bread... VIPRs. www.biorxiv.org/content/10.6... www.biorxiv.org/content/10.6...

Could this be my finest moment? '"Your average space billionaire probably doesn't give a rat's arse about future generations," she said'. I'm not sure I was expecting this to be quoted! 🧪

Complementary Holliday Junction observations now available to absorb from @martinxaver.bsky.social and coauthors! www.biorxiv.org/content/10.6...

Commentary: How do authors want to use AI for review? link.springer.com/article/10.1...

On #NationalSpinachDay, this graphic looks at the real story behind spinach’s iron content: www.compoundchem.com/2018/07/17/s...#NationalSpinachDay #ChemSky 🧪

Amazing to receive the @hfspo.bsky.social Research Grant to pursue the project I have been dreaming of since I started my lab..!!🧬: how meiotic drive impacts sex ratios in vertebrates👩🏻‍🔬👨‍🔬 I am so fortunate to collaborate on this project with Jiri Hejnar at IMG and @amarques.bsky.social 🎉🙏🏼

JOIN US!: PhD applications are still open. Deadline extended until 6th April due to Easter break. www.findaphd.com/phds/project...

Meiosis alert! Last few days to register for #BMM2026. Calling all postdocs/PhD students: your chance to meet the community, give a talk, present your poster! Hosted at the beautiful Royal Society HQ in London this year! www.rothamsted.ac.uk/event/xvi-br...

Condensin loop extrusion properties, roadblocks, and role in homology search @aurelepiazza.bsky.social et al show yeast condensin unidirectionally extrudes long chromatin loops & contributes to biasing donor selection during recombinational DNA break repair link.springer.com/article/10.1...

Spring is here in the northern hemisphere! Here's a graphic from the #PeriodicGraphic archives in @cenmag.bsky.social looking at the pigments that give daffodils their golden glow: cen.acs.org/articles/93/... #PeriodicGraphic#ChemSky 🧪

Chair in Earth Sciences position @uniofstandrews.bsky.social closing soon - Monday 23 March. Very broad remit, so if you’d like to join our lovely school, and get to live in the super beautiful and friendly wee nation of Scotland, please apply! www.st-andrews.ac.uk/earth-scienc... ⚒️🌊🧪

Wow. @pallabg.bsky.social has a obtained leaked document from STFC Council suggesting the origin of the STFC funding crisis was a deliberate decision (by?) 🧪🔭 www.bbc.co.uk/news/article...

Associate Senior Lecturer/Assistant Professor position in Molecular Microbiology available at Lund University, Sweden: lu.varbi.com/en/what:job/...

Fantastic to share the work of @whgittens.bsky.social and Tom Powell. World-first detection of Topoisomerase 3 activity on chromosomes in vivo. Top3 maps to meiotic hotspots then migrates, indicating that branched Holliday junctions migrate codirectionally with transcription; resolve at the axis.

Some of my favourite plants 🙃

Two weeks left to get in your applications! ✍️ www.sussex.ac.uk/study/fees-f...

Pregnancy loss is common in humans, and chromosomal abnormalities are the leading cause. Using genetic data from ~140,000 IVF embryos, we show that maternal variation in meiosis genes influences recombination and aneuploidy risk. First authors: @saracarioscia.bsky.social & @aabiddanda.github.io

After a long incubation, it is a huge pleasure to finally share the work of @luzmlopez.bsky.social, Jon Harper and their coauthors: "Localised negative feedback shapes genome-wide patterning of meiotic DNA breaks". @gdsc-sussex.bsky.social www.biorxiv.org/content/10.6...

Now live on Find-A-PhD-dot-com: Joint project between @labneale.bsky.social and @drjonbaxter.bsky.social @gdsc-sussex.bsky.social Get in touch if you are interested in any and all of: Chromosomes, Genome Stability, Chromatin and DNA Topology in Mitosis and Meiosis. www.findaphd.com/phds/project...

@science.org A small polymerase ribozyme that can synthesize itself and its complementary strand | Science www.science.org/doi/10.1126/... #RNA #ribozyme #evolution

Indeed! And this depiction is just of one... www.nature.com/articles/sre...

NOW LIVE!: PhD opening joint with @drjonbaxter.bsky.social at @gdsc-sussex.bsky.social Get in touch and apply if you are interested in any and all of: Chromosomes, Genome Stability, Chromatin and DNA Topology in Mitosis and Meiosis. www.sussex.ac.uk/study/fees-f...

Super strong representation from our department in SussexRNA at the RNA UK meeting in Windermere this week. Many congrats to Jake, Courtney and Hope from the Ben Towler group, and Leandro Castellano, Lidia Vasilieva, Ben and Nikos for having abstracts accepted for presentation. 👏

Beautiful! Is this in real time (20 seconds?) (Speed also seem to slow over time?)

Changes in the UK R&I funding landscape - doing fewer things better. An open letter from Ian Chapman to research and innovation community: www.ukri.org/news/open-le...

"Writing papers is rarely (probably never) the rate-limiting step in scientific research" Important to remember this. However painful writing is, however much more efficient we can make it, for experimental work it's the research that takes the time. www.linkedin.com/feed/update/...

Coming soon! PhD opening joint with @drjonbaxter.bsky.social at @gdsc-sussex.bsky.social Keep a look out and get in touch if you are interested in any and all of: Chromosomes, Genome Stability, Chromatin and DNA Topology in Mitosis and Meiosis.

Still some time to register to this great meeting! Great science and great location for a very affordable registration cost!

It’s a massive problem across the sector, and I’m not sure what is the solution is…

Human eggs must segregate their chromosomes with exquisite precision — yet errors rise with maternal age, causing miscarriage & infertility. Our new article on @biorxivpreprint.bsky.social shows why chromosome cohesion fails in aging eggs & how to improve it. www.biorxiv.org/content/10.6... (1/10)

Skip to 1m 39s for my current coding hobby project 🙃

30 years ago today, December 31st 1995, the last ever Calvin & Hobbes comic strip was published. Even now, I still find it so poignant & moving.

SMC and recombination enthusiasts: we updated our work describing the loop extrusion properties of budding yeast condensin and its function in biasing donor usage for mating-type switching. Lots of cool new data, check it out! www.biorxiv.org/content/10.1...

Do #hybrids handle heat, cold better? ❄️🔥 Over 140 generations at 5C and 31C, #yeast #F2 hybrids adapted fast, were ~4× fitter in cold, more resilient to sudden flips. #Hybridization could turbocharge #adaptation, impacting #conservation & #agriculture. #Evolution www.yeastgenome.org/reference/41...

Large and intricate naturally occurring structures composed exclusively of RNA... ROOL! More at Molecule of the Month: pdb101.rcsb.org/motm...

Leanna Owen, Margot Riggi , David Drubin, Janet Iwasa and Yidi Sun use molecular animation to depict the full progression of CME in budding yeast, with an accompanying Cell Science at a Glance article and poster. journals.biologists.com/jcs/article/...

While 𝘝. 𝘷𝘦𝘳𝘮𝘪𝘧𝘰𝘳𝘮𝘪𝘴 max temp is around 45°C, we found 𝘐. 𝘤𝘢𝘴𝘤𝘢𝘥𝘦𝘯𝘴𝘪𝘴 grows up to 63°C with optimal growth at 55-57°C🥵. We showed cellular replication via Ultrastructure Expansion Microscopy at 63°C. The previous limit for euks is 60°C!

Bye bye Edinburgh - such a lovely trip! Thanks to @marstonlab.bsky.social @owendavi77.bsky.social !

Successful change at Euston. Train is standing room only though due to a prior cancellation 😱 Very glad I booked a seat and it is still reserved!

Departure: Brighton 13:40 (Due Edinburgh 20:24) 😁

New research from Valerie Garcia and colleagues: Tel1 is recruited at chromosomal loop/axis contact sites to modulate meiotic DNA double-strand breaks interference journals.plos.org/plosgenetics...

Happy to share the “International Symposium on Chromosome Dynamics: from Structure to Cellular Function” that will be held in Japan 31st of May 2026 www.fbs.osaka-u.ac.jp/labs/fukagaw.... Registrations will open on December 1st! Plenty of opportunities to present your work! Hope to seeing you

Using #yeast, Yu et al show templated insertions at double-strand breaks in cancers arise from foldback mechanism involving microhomologies. Lack of RPA may drive this process, shedding light on cancer's genetic instability #CancerResearch #Genetics #DNARepair www.yeastgenome.org/reference/39...

Delighted to see our study finally out in "print". Thanks to all the (many) contributors, collaborators and reviewers! Mismatch repair disturbs meiotic crossover control in S. cerevisiae academic.oup.com/nar/article/...

Matching T-shirt and slide @gdsc-sussex.bsky.social from Sir Paul Nurse

Fantastic celebration of Tony Carr’s scientific career at the @gdsc-sussex.bsky.social retreat 2025

Vital piece of investigative reporting from Sky. They've uncovered the X algorithm which feeds users extremist right wing material from the moment they join the site. It is a far-right radicalisation engine, by design. news.sky.com/story/the-x-...