We are joined by Arun Shukla, Indian Institute of Technology, Kanpur, on the structure, function and regulation of GPCRs; and Lauren Porter, NIH, on using AlphaFold's 'black box' to predict the conformations of fold-switching proteins. Lorne Proteins 2026 🏖️ 🔗 Register today: www.lorneproteins.org

𝐏𝐫𝐞𝐬𝐞𝐧𝐭 𝐚 𝐩𝐨𝐬𝐭𝐞𝐫 𝐚𝐭 𝐭𝐡𝐞 𝟓𝟏𝐬𝐭 𝐋𝐨𝐫𝐧𝐞 🏖️ 𝐏𝐫𝐨𝐭𝐞𝐢𝐧𝐬 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞 🤩!! 𝐃𝐨𝐧'𝐭 𝐦𝐢𝐬𝐬 𝐭𝐡𝐢𝐬 𝐨𝐩𝐩𝐨𝐫𝐭𝐮𝐧𝐢𝐭𝐲 𝐭𝐨 𝐩𝐫𝐞𝐬𝐞𝐧𝐭 𝐭𝐨 𝐞𝐱𝐩𝐞𝐫𝐭𝐬 𝐢𝐧 𝐩𝐫𝐨𝐭𝐞𝐢𝐧 𝐬𝐭𝐫𝐮𝐜𝐭𝐮𝐫𝐞, 𝐟𝐮𝐧𝐜𝐭𝐢𝐨𝐧, 𝐛𝐢𝐨𝐜𝐡𝐞𝐦𝐢𝐬𝐭𝐫𝐲, 𝐛𝐢𝐨𝐩𝐡𝐲𝐬𝐢𝐜𝐬, 𝐜𝐨𝐦𝐩𝐮𝐭𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐛𝐢𝐨𝐥𝐨𝐠𝐲 𝐚𝐧𝐝 𝐚 𝐰𝐡𝐨𝐥𝐞 𝐥𝐨𝐭 𝐦𝐨𝐫𝐞... 🌊 ☀️ 🏐 😎 🔗 𝐏𝐨𝐬𝐭𝐞𝐫 𝐚𝐛𝐬𝐭𝐫𝐚𝐜𝐭 𝐬𝐮𝐛𝐦𝐢𝐬𝐬𝐢𝐨𝐧 𝐜𝐥𝐨𝐬𝐞𝐬 𝐓𝐎𝐃𝐀𝐘! www.lorneproteins.org

Lorne Proteins 2026 🏖️ Leach Lecturer Carol Robinson, Oxford, on establishing mass spec as a viable technique for structure/function studies; and John Kuriyan, Vanderbilt University, on the structural plasticity and evolutionary potential of DNA clamp loaders. 🔗 Register now: www.lorneproteins.org

🏨 🛌 Don’t miss staying at Mantra Lorne – bookings close 5 December! Make the most of the full Lorne Proteins experience by staying where the action is. 🌊 Ocean views, a short walk to the lecture theatre, and the perfect setting for collaboration. 😎 🔗 Book accommodation here: www.lorneproteins.org

(っ◔◡◔)っ ♥ 𝐇𝐚𝐯𝐞 𝐲𝐨𝐮 𝐫𝐞𝐠𝐢𝐬𝐭𝐞𝐫𝐞𝐝 𝐟𝐨𝐫 𝐋𝐨𝐫𝐧𝐞 𝐏𝐫𝐨𝐭𝐞𝐢𝐧𝐬 𝐲𝐞𝐭? ♥ Join leading researchers, students and industry partners in Lorne 🏖️ for an inspiring week of science and collaboration. Secure your place today and ensure you’re part of the 2026 program. 🔗 Register now: www.lorneproteins.org

Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...

On the way to the tail end of #CryOz2025 for a #cryoET workshop. 🚉 Can we acquire wedges of EVs on the #AdelaideUniversity #Glacios and reconstruct something meaningful? Looking forward to finding out 😁 @molecularhorizons.bsky.social Thanks #MicroscopyAustralia for support to attend.

🌐🧬I am excited to present you a round table I am doing together with Matteo Marengo Gabriel Michaux as part of our emerging Nucleate Parisian chapter led by Clara Brouaux 🔥. Title: **Inside AI: Choosing the Right Path to Value Creation** 1/3

Delighted to be involved in this study aiming to address limitations in mRNA nanoparticle stability to improve access to critical vaccine technologies-out now in Advanced Science. Cryo-EM imaging & statistical analysis of LNP microstructures shows reduced degradation at elevated temps 🫰

📣 Abstract Deadline Extended! Due to popular demand, we’ve extended the submission deadline — giving you a few extra days to finalise your abstract. Don’t miss out on being part of Lorne’s legacy! 👉 Submit today: www.lorneproteins.org #LorneProteins #DeadlineExtended #ProteinScience

#AusBiotech kicked off with an enlightening session on curating #Bioprecincts and the essentiality of a good coffee shop! Today marks the official start of this inspiring global meeting. Finding out where #AdelaideBioMedCity research & workforce training fit into our national #biomedtech capability.

🌟 Conference Support Opportunities Available Help emerging researchers and students attend Lorne Proteins through travel and registration bursaries. Learn more and make a difference here 👉 www.lorneproteins.org/conferencesu... #LorneProteins #FutureScientists #ScienceSupport

📢 Call for Abstracts – One Month to Go! Don’t miss your chance to present at the 51st Lorne Proteins Conference. Share your research, connect with global scientists, and be part of a legacy 51 years strong. 👉 Submit your abstract now: www.lorneproteins.org #LorneProteins #ProteinScience

🎨 Design the Next Lorne Proteins T-Shirt! Got an eye for design? We’re calling on creative scientists to design the official 2026 conference T-shirt! 📅 Entries close 10 November 2025 👉 Submit your design here: #LorneProteins #TshirtCompetition #CreativeScience

Lorne 2026 is set to be excellent! Especially with a Transporter Satellite Meeting!!

📢 𝙰𝚋𝚜𝚝𝚛𝚊𝚌𝚝 𝚂𝚞𝚋𝚖𝚒𝚜𝚜𝚒𝚘𝚗𝚜 𝙲𝚕𝚘𝚜𝚒𝚗𝚐 𝚂𝚘𝚘𝚗!! 𝙳𝚘𝚗’𝚝 𝚖𝚒𝚜𝚜 𝚢𝚘𝚞𝚛 𝚌𝚑𝚊𝚗𝚌𝚎 𝚝𝚘 𝚜𝚑𝚊𝚛𝚎 𝚢𝚘𝚞𝚛 𝚛𝚎𝚜𝚎𝚊𝚛𝚌𝚑 𝚊𝚝 𝚝𝚑𝚎 𝙻𝚘𝚛𝚗𝚎 𝙿𝚛𝚘𝚝𝚎𝚒𝚗 𝙲𝚘𝚗𝚏𝚎𝚛𝚎𝚗𝚌𝚎 𝟸𝟶𝟸𝟼. 𝙰𝚋𝚜𝚝𝚛𝚊𝚌𝚝 𝚜𝚞𝚋𝚖𝚒𝚜𝚜𝚒𝚘𝚗𝚜 𝚌𝚕𝚘𝚜𝚎 𝟸𝟺𝚝𝚑 𝙾𝚌𝚝𝚘𝚋𝚎𝚛 – 𝚜𝚑𝚘𝚠𝚌𝚊𝚜𝚎 𝚢𝚘𝚞𝚛 𝚠𝚘𝚛𝚔 𝚝𝚘 𝚝𝚑𝚎 𝚐𝚕𝚘𝚋𝚊𝚕 𝚙𝚛𝚘𝚝𝚎𝚒𝚗 𝚜𝚌𝚒𝚎𝚗𝚌𝚎 𝚌𝚘𝚖𝚖𝚞𝚗𝚒𝚝𝚢 𝚒𝚗 𝚐𝚕𝚘𝚛𝚒𝚘𝚞𝚜 𝙻𝚘𝚛𝚗𝚎! 🏖️ 🏄‍♀️ 🏊 👉 𝚂𝚞𝚋𝚖𝚒𝚝: www.lorneproteins.org/submissions

𝐓𝐡𝐞 𝐀𝐧𝐝𝐞𝐫𝐬 𝐀𝐰𝐚𝐫𝐝 recognises up to 5️⃣ scientists who are within 5 years of their PhD, with a talk secured in a dedicated session! It’s always a highlight of the meeting & a fantastic opportunity to showcase exciting new science 🤩 𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬 𝐜𝐥𝐨𝐬𝐞 𝟐𝟒 𝐎𝐜𝐭𝐨𝐛𝐞𝐫 𝟐𝟎𝟐𝟓: www.lorneproteins.org/submissions

Anyone in #SouthAustralia culturing Karenia mikimotoi? #AlgalBloom #brevetoxin

Please like and share 🙏🫶

👇 We want you! Don’t miss out on our inaugural "Indigenous Researcher Award" from the Lorne Proteins conference. Full support to attend the 2026 conference. Deadline October 24. www.lorneproteins.org/researcher

Martini 3, where did my fourth chain go?

Momentum is building! Join us for the 51st Lorne Proteins Conference Feb 8–12, 2026, Mantra Lorne on the Great Ocean Road, for fun networking activities 🏐 🎾 🥗 🪩 and breathtaking surf-coast accessibility 🏖️ 🏊 🏄 in the generous breaks between sessions! 🔗 Register here: www.lorneproteins.org/register

With a delegation visiting IIT Roorkee- Great to meet Pravindra Kumar and Saugata Hazra and tour the amazing facilities here. The student talks were excellent 👏👏 Thanks for having us Roorkee!

Applicants wanted 2: Open position for Postdoc Researcher for Developing Microfluidics for Research on Synthetic Cells careers.tudelft.nl/job/Delft-Po...

Applicants wanted 3: Open position for Postdoc Researcher for Single-molecule Protein Sequencing with Origami Nanopores careers.tudelft.nl/job/Delft-Po...

Applicants wanted 4: Open position for Postdoc Researcher for Studying in Vitro Transport Across the Nuclear Pore Complex careers.tudelft.nl/job/Delft-Po...

🥁🥁🥁 The 51st Lorne Conference on Protein Structure and Function is officially live! After the resounding success of the 50th Lorne Conference in 2025 celebrating five decades of pioneering science and community, the legacy continues... 🏄🏖️🌞 February 8–12, 2026 Register here: www.lorneproteins.org

(1/7) Training biomolecular foundation models shouldn't be so hard. And open-source structure prediction is important. So today we're releasing two software packages: AtomWorks and RosettaFold3 (RF3) [https://www.biorxiv.org/content/10.1101/2025.08.14.670328v2](www.biorxiv.org/content/10.1...)

For lovers of #crystallography: The latest issue of the @IUCr Newsletter is out at www.iucr.org/news/newslet....

Stoked to finally have a preprint out for Phold, our tool that uses protein structural information to enhance phage genome annotation #phagesky 1/n www.biorxiv.org/content/10.1...

Get Ready to Empower the Next Generation of Scientists at Glycopalooza 2025!! 🥳 As part of the 52nd SFG Annual Meeting, Glycopalooza 2025 is a trainee-focused event designed to empower the next generation of scientists through mentoring, career exploration and community building ⬇️

🦠🧍‍♀️From bacterial to human immunity. We report in @science.org the discovery of a human homolog of SIR2 antiphage proteins that participates in the TLR pathway of animal innate immunity. Co-led wt @enzopoirier.bsky.social by D. Bonhomme and @hugovaysset.bsky.social www.science.org/doi/10.1126/...

Tenure-track faculty search of the UCSF Biochemistry & Biophysics Department is open for applications! We are looking for creative, innovative scientists asking fundamental questions in any area of biology. Join our vibrant, collaborative, and supportive community! aprecruit.ucsf.edu/JPF05702

🧬🧶

When particles have orientation bias, the resulting maps are often streaked along the missing directions. In this case study, we cover why orientation bias produces anisotropic #cryoEM maps and how you may be able to recover from it! guide.cryosparc.com/processing-d...

go.bsky.app/8zZNEGV Great resource to connect early career folks with more senior scientists looking to hire postdocs! 🧪

A great review from Na Li et al., Bing-Zhi Li and Zhi-Hua Liu highlighting the importance of discovery of novel O-demethylases for #greenchemistry recovery of valuable compounds from renewable aromatic biopolymers in #lignin (~150 million tonnes per annum) via #bioconversion tinyurl.com/2km28b4y

Exciting Leadership Opportunity - Applications are open for role of Co-Director, Brain and Mind Centre at the @Sydney_Uni #LeadershipforGood ☑️ Find out more and apply here: lnkd.in/gUGmJSfn @ian-hickie.bsky.social

Delighted to share that I will be starting a new role as Senior Lecturer in Biotechnology at the University of Adelaide, (aka Adelaide University in 2026) 🎉 . I will continue supporting cryo-EM for SA researchers in an academic capacity at Adelaide Microscopy 🔬 Onwards and upwards!

A really engaging TIBS Spotlight article highlighting our recent structures of a cytochrome P450 SyoA. Thanks to Professor Jennifer DuBois for elegantly contextualising the work within the broader field of lignin valorisation. Upcycling lignin with a controlled burn tinyurl.com/2s3w9ej6 🔥🫰

Great to be involved in this research on the Ghrelin receptor, out now in Molecular Cell - with potential for translation to improve quality of life for Parkinson's disease patients! Download now for free via this link: authors.elsevier.com/c/1lARg3vVUP... www.uq.edu.au/news/article...

Postdoc opportunity, please share! We are looking for a #postdoc to join our international team* in our quest to understand how Type 4 Secretion Systems facilitate the transfer of #antibioticresistance genes and other virulence factors in Gram-positive #bacteria.🧫👇 *5 people & 5 nationalities 🇸🇪🇳🇱🇳🇿🇺🇸🇪🇬

🇨🇦 Come be our colleague! @uottawascience.bsky.social is hiring a supervisor for our X-Ray Core Facility, with new high end equipment coming soon. Ottawa is a beautiful place to live. Please share widely! 10 days left to apply: uottawa.wd3.myworkdayjobs.com/en-US/uOttaw...

Just a reminder that our tenure track group leader position in the Structural Studies Division of @mrclmb.bsky.social will close in four days! mrc.tal.net/vx/lang-en-G...

Uni of Wollongong Cryo EM job closes on Sunday people! @gokhan-tolun.bsky.social might be able to answer questions? 🧬🧶

Tesla Model 3 crushed by an Olmec statue By Mexican sculptor @chavismarmol.bsky.social

Tomorrow is the last day to apply!

Happy to share that the final version of record for our ( @nanigrotjahn.bsky.social) #teamtomo mitochondrial cotranslation story is online at @jcb.org! We combined STA with surface morphometrics to learn how ribosomes bind to and alter mitochondrial membranes in yeast. rupress.org/jcb/article/...

On this eve of the @standupforscience.bsky.social day, I would like to express my deepest and most sincere solidarity with all scientists in the USA in these troubled times, and more generally with all honest scientists in all countries and all American citizens fighting for human progress.