🧠📢 New preprint alert Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵 #neuroskyence #compneurosky

(1/6) We have a new paper out in #eNeuro! How does the brain’s reward processing change across social contexts? We mapped brain activity (cFos) & found that social context reshapes how reward circuits are coordinated🐭🏆 Read more: www.eneuro.org/content/12/1...

1. New preprint resolving a conundrum in systems neuroscience with an AI scientist, and humans Reilly Tilbury, Dabin Kwon, @haydari.bsky.social, @jacobmratliff.bsky.social, @bio-emergent.bsky.social, @carandinilab.net, @kevinjmiller.bsky.social, @neurokim.bsky.social www.biorxiv.org/content/10.1...

🚨 Reminder: Applications for #OptoGRC2026 are now OPEN! Don’t miss your chance to join an incredible week of science, discovery, and connection with the brightest minds in optogenetics 💡🧠 Apply now for the best chance of acceptance: www.grc.org/optogenetic-...

NOT TO MISS! In @mountsinainyc.bsky.social's 2025 issue of Science & Medicine magazine, Dean @ericjnestler.bsky.social discusses his vision for Icahn Mount Sinai, and how his distinguished academic career & research expertise have prepared him. 👉 scienceandmedicine.mountsinai.org/article/2025...

A Special Congratulations to @ericjnestler.bsky.social on receiving the 2025 Synapsy Prize. This prestigious award celebrates lifelong dedication to translating fundamental neuroscience discoveries into tangible clinical advancements in mental health. Learn More 👉 www.eurekalert.org/news-release...

Stop by our posters tomorrow afternoon at #SFN25!! #sfn2025 @sfn.org #neuroscience

✨ New preprint ✨ What if we could watch AND control thousands of individual neurons in behaving mice—with stable access over months? 🧠⚡ Our work introduces transgenic all-optical tools that make this possible - and a resulting surprising discovery! 🔭💡 www.biorxiv.org/content/10.1... 1/13 🧵

Our Behavioural Brain Research special issue on Ultrasonic Communication in Rodents is growing, rapidly – and actually a lot faster than I manage to post about it. Nine new manuscripts got accepted since my last post. Quite impressive work. Check it out: www.sciencedirect.com/special-issu...

📣We are hiring! 📣 
Join us as a Postdoctoral Researcher to study brain–body interactions uncovering how neural and physiological systems regulate behavior and energy metabolism under stress! Details are below: 📩 [email protected]
🔗 careers.mountsinai.org/jobs/3032214

For those heading to #SfN25, come check out our posters on Saturday Afternoon! The lab is growing & expanding in several new directions & collabs #neuroeconomics 🧠🐭🧠 @sinaibrain.bsky.social @sinaiccp.bsky.social @sfn.org @socforneuroecon.bsky.social @bwfund.bsky.social @animalsocaging.bsky.social

"The way forward has become very clear"- Dr. Brendan G. Carr A HUGE CONGRATULATIONS to @ericjnestler.bsky.social named Anne & Joel Ehrenkranz Dean of the Icahn School of Medicine. We’re thrilled about the exciting new direction Icahn Mount Sinai will take under Dr. Nestler's visionary leadership!

When I moved to BCM, an extremely talented movement disorders neurologist, Nora Vanegas Arroyave, reached out to discuss brain circuits responsible for non-motor deficits in Parkinson's Disease. I have learned so much from her and from this collaboration. One paper out, more to come!

We are also considering applications from undergraduate students and Master's students in the local New York City area! Please check out our website for more information on how to become involved: sinclaboratory.com/apply

Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...

🚨 New science alert! Our cross-species study, now in Nature Neuroscience, demonstrates psychedelics distort how we should interpret functional brain imaging. 👇🧵 nature.com/articles/s41... #Neuroscience #Psychedelics #BrainImaging

Excited to share that I landed my dream job!🎉🎉🎉 The Pennington Lab will be opening at the University of British Columbia in January 2026! @ubcpsych.bsky.social @dmcbrainhealth.bsky.social

We're looking forward to the first annual New York Memory Hub conference later this week! Can't wait for all the talks and discussion about all things learning and memory 🧠

So excited for this! Can't wait to see everyone there!

The amygdala helps mobilize #Stress hormones cortisol & adrenaline w/in about 15 minutes. A recent study by Icahn Mount Sinai's Dr. Sarah Stanley suggests a 2nd role for the #Amygdala in response to #Fear & #Anxiety. Dr. Stanley discusses her research @pnas.org 👉 www.pnas.org/post/journal...

The Sosa Lab website is now live! www.sosaneurolab.com We will be seeking a postdoctoral researcher to join the growing team! If you are a rodent neuroscientist and interested in doing systems neuro work in the mountains 🏔️, please check out the "Join" page.

#FluorescentFriday The lab’s 1st slice physiology recordings! Timelapse recording of striatal neurons ex vivo using a Thy1-GCaMP mouse 🐭 🧠 + glutamate in the bath. Thanks @neuromanonyc.bsky.social! Shout out to @keyenceusa.bsky.social who has been great to work with customizing the BZ-X800🔬

Couldn’t be more excited to see this work out!! Not just manipulating PV+ cell theta phase, but also shifting seizure susceptibility! how much cooler can it get?!!!

Check out new work from our lab! We developed a new way to directly control the precise timing of interneurons during behavior and found that theta phase locking is a causal mediator of seizure susceptibility in both healthy and epileptic mice.

🚨New preprint alert🚨 We used closed-loop optogenetics to causally test the importance of inhibitory spike timing in network function and found that manipulating PV+ cell theta phase locking in the dentate gyrus can shift seizure susceptibility (both ways!)

Neuro Current Ep. 38 features #JNeurosci authors discussing their paper on disrupted choice behaviors in a rat model of FASD. Listen to learn more about their methods. 🎧Listen: vist.ly/45w9g 📺 Watch on demand: vist.ly/45w99

Congrats Herbert and team!

Research Network 2023 Pilot & Feasibility awardee @brianmsweis.bsky.social published two papers in Science Advances in July of this year that feature his research on the neuroeconomics of decision making. Join us in congratulating Dr. Sweis! shorturl.at/d65WV shorturl.at/DoU4p

Welcome to one of our newest @acnporg.bsky.social Associate Members, Dr. Brian Sweis 🎉 #WelcomeToACNP👋

Congrats to Brian Sweis, M.D., Ph.D. a new Associate Member of ACNP! Welcome!! 👋

Abstract submission open for The Mechanistic Basis of Foraging 2025 (U. Birmingham, 3-5 November) uobevents.eventsair.com/the-mechanis... Deadline: August 17 A meeting for all fascinated by the brain's role in foraging Pls share!

This speaks to the importance of cross-species research that is constantly forward- & back-translated between the clinic & lab. The importance of animal models leading to unanticipated discoveries - even in the realm of human psychology - is invaluable, especially in psychiatry🧠 tinyurl.com/yur3j2n8

New paper alert!🚨📝 Paper: tinyurl.com/2cycsy6d Press release: tinyurl.com/yur3j2n8 How the brain 🧠 engages in change-of-mind decisions taps into cognitive biases that depend on sensitivity to sunk costs & regret - both of which may contribute to negative rumination…however…🧵👇1/6 #ScienceAdvances

What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope! Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals. Read the paper here: www.science.org/doi/10.1126/... (1/10)

Last day for early-career scientists (advanced PhD, postdoc, and faculty) to apply for a McEwen Fellowship, an up-to-$6,000 individual award available for research related to animal models and the social determinants of health and aging. Apply here: www.animalsocialaging-network.org/funding/fell...

"Science is an investment. We will put forward a new 500 million package for 2025-2027 to support the best and the brightest researchers and scientists from Europe and around the world." — President @vonderleyen.ec.europa.eu at the ‘Choose Europe for Science' event at La Sorbonne 🇫🇷

Application now open: Career Awards for Medical Scientists (CAMS) is a highly competitive program that provides $700,000 awards over five years for physician-scientists, who are committed to an academic career. buff.ly/VdljzxQ #bwfcams

Important PSA: #NeuroEconomics is an "or" not an "and" descriptor. You can be neuro, econ, or a little of both and we want to hear your work at Neuroecon this fall! (You can also be a psychologist, or consumer behavior-ist and we want to hear you too - go ahead ask me how I'd know 😁)

Do you do research on decision-making? We want to hear it! Late-breaking abstract submission for the Society for Neuroeconomics fall conference in Cambridge MA is *open*. Submit your work and come hang out with us this fall! neuroeconomics.org/abstract/

This was a really fun project: We blocked obesity in mice by making them do a tiny bit of work for their food. www.sciencedirect.com/science/arti...

Remider! Applications for the McEwen Career Development fellowship in Social Determinants of Health supported by the NIA-BSR High Priority Research Network animalsocialaging-network.org are now open! apply here animalsocialaging-network.org/funding/fell...

Great piece from @thetransmitter.bsky.social about the field’s current understanding of the hippocampus! Honored for the nod to our recent paper among these many other excellent studies www.thetransmitter.org/memory/expan...

Love this 👏

10 years of social dynamics and over a year of vocalization by wild mice in the wild, simply amazing! Great work by @nickjourjine.bsky.social at the very precious mouse barn established by Barbara König

Very happy to share the latest from my postdoc‬! 10 yrs of mouse social networks + 1.25 yrs of acoustic data ➡️ insight into vocalization & sociality in a wild population of your favorite lab model 🐁 paper: bit.ly/4n93yyD data: bit.ly/4lfFBEk code: bit.ly/4kNnMwx #bioacoustics #neuroskyence 1/8

The application window for our Pilot awards and McEwen fellowship closes soon! If you have a project proposal that focuses on animal models and comparative studies to study the social elements of human aging, we encourage you to apply! See more here: www.animalsocialaging-network.org/funding/

NEW: Judge Young, a 1985 Reagan appointee, delivered an extended rebuke of the Trump administration’s crackdown research grants it seems related to DEI or gender ideology. w/ Danny Nguyen www.politico.com/news/2025/06...

MORE YOUNG: "It is palpably clear that these directives and the set of terminated grants here also are designed to frustrate, to stop, research that may bear on the health – we’re talking about health here, the health of Americans, of our LGBTQ community. That’s appalling."

YOUNG: "I am hesitant to draw this conclusion, but I have an unflinching obligation to draw it – that this represents racial discrimination. And discrimination against America’s LGBTQ community. That’s what this is. I would be blind not to call it out. My duty is to call it out."