Sarah Cherkaoui
@cherkaos.bsky.social
📤 22
đź“Ą 73
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Postdoc - Rabinowitz lab @Princeton
🚨 Excited to share our new paper is out in Nature! 🔗 Reprogramming neuroblastoma by diet-enhanced polyamine depletion
add a skeleton here at some point
21 days ago
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reposted by
Sarah Cherkaoui
Nature
26 days ago
Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation
go.nature.com/46nMxKQ
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A drug–diet combination could improve childhood cancer treatment
Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation.
https://go.nature.com/46nMxKQ
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reposted by
Sarah Cherkaoui
Barbara Marte
24 days ago
and the News & Views
www.nature.com/articles/d41...
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A drug–diet combination could improve childhood cancer treatment
Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation.
https://www.nature.com/articles/d41586-025-02824-z
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reposted by
Sarah Cherkaoui
Barbara Marte
24 days ago
new out in Nature
www.nature.com/articles/s41...
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Reprogramming neuroblastoma by diet-enhanced polyamine depletion - Nature
Enhanced polyamine depletion in neuroblastoma models decreases translation of mRNA codons with adenosine in the third position, reprogramming the tumour proteome away from cell cycle progression and towards differentiation.
https://www.nature.com/articles/s41586-025-09564-0
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