Sarah Cherkaoui
@cherkaos.bsky.social
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Postdoc - Rabinowitz lab @Princeton
reposted by
Sarah Cherkaoui
NCCR RNA & Disease
2 months ago
Publication by the Morscher Lab & collaborators, including the Leidel lab w/ 1st author Sarah Cherkaoui "Reprogramming neuroblastoma by diet-enhanced polyamine depletion"
@nature.com
NCCR News:
nccr-rna-and-disease.ch/news/article...
@cherkaos.bsky.social
@mcm5s2u.bsky.social
@unibe.ch
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🚨 Excited to share our new paper is out in Nature! 🔗 Reprogramming neuroblastoma by diet-enhanced polyamine depletion
add a skeleton here at some point
3 months ago
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reposted by
Sarah Cherkaoui
Nature
3 months ago
Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation
go.nature.com/46nMxKQ
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A drug–diet combination could improve childhood cancer treatment
Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation.
https://go.nature.com/46nMxKQ
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reposted by
Sarah Cherkaoui
Barbara Marte
3 months ago
and the News & Views
www.nature.com/articles/d41...
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A drug–diet combination could improve childhood cancer treatment
Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation.
https://www.nature.com/articles/d41586-025-02824-z
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reposted by
Sarah Cherkaoui
Barbara Marte
3 months ago
new out in Nature
www.nature.com/articles/s41...
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Reprogramming neuroblastoma by diet-enhanced polyamine depletion - Nature
Enhanced polyamine depletion in neuroblastoma models decreases translation of mRNA codons with adenosine in the third position, reprogramming the tumour proteome away from cell cycle progression and towards differentiation.
https://www.nature.com/articles/s41586-025-09564-0
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