A study in a mouse model of 𝘔𝘠𝘊𝘕-amplified neuroblastoma implicates polyamine levels in affecting the makeup of the proteome and biologic characteristics of the tumor. Learn more in the Clinical Implications of Basic Research article “Altering the Diet to Rewire Cancer”: nej.md/41m5Xwl #Oncology

Publication by the Morscher Lab & collaborators, including the Leidel lab w/ 1st author Sarah Cherkaoui "Reprogramming neuroblastoma by diet-enhanced polyamine depletion" @nature.com NCCR News: nccr-rna-and-disease.ch/news/article... @cherkaos.bsky.social @mcm5s2u.bsky.social @unibe.ch @snsf.ch

🚨 Excited to share our new paper is out in Nature! 🔗 Reprogramming neuroblastoma by diet-enhanced polyamine depletion

Mouse studies show that depriving neuroblastoma of certain amino acids causes a switch in protein synthesis to suppress tumour growth and promote cell differentiation go.nature.com/46nMxKQ

and the News & Views www.nature.com/articles/d41...

new out in Nature www.nature.com/articles/s41...