📣 Our lab is recruiting postdocs to lead new fully funded projects on mechanisms of microbiome–gut–brain signaling & microbial regulation of brain–body interactions in disease, w supportive clinical collaborators. Expertise in gut–brain, systems neuro, or neuroimmunology preferred. Please email 📧

Microbe-mediated stress? Microbial metabolite Imidazole propionate reaches brain, dampens hypothalamic activity & promotes stress-related behaviors. In humans, higher ImP is associated w/reduced hypothalamic responses & emotional eating @pipethero.bsky.social www.cell.com/cell-host-mi...

Excited to share new work by Guli Agirman + co that identifies a direct mechanism linking gut microbial imidazole propionate to stress! 🧠🦠 Btw this image was made by Nano Banana Pro 🍌. First time I've gotten a model to accurately generate a science graphic 🤯 authors.elsevier.com/a/1mA5M6t8JE...

Happy to share this paper in final form rdcu.be/eH8tj, with more info on neuronal responses and potential mechanism of actions! The results suggest that there is neural interoception of microbial metabolic state 🧠🦠 We hope they can inspire more work in this area!

Delighted to share this perspective piece by Lewis Yu on microbial regulation of serotonin and neuroimmune interactions. Looking forward to sharing more on this topic soon 🤞 www.sciencedirect.com/science/arti...

5/5 Awardee @chuchuzhang.bsky.social explores how different body states (eg, pregnancy) may change what neurons sense & how they respond. Her work may lead to new ways to address nausea associated w/ pregnancy🤰 & chemo. 🍾Congrats Dr. Zhang! @dgsomucla.bsky.social 🙏 #HFScout @pipethero.bsky.social

🧪our paper in @cp-cellhostmicrobe.bsky.social selected as NIEHS papers of the month! 🔥🔥 pubmed.ncbi.nlm.nih.gov/40315838/ @pipethero.bsky.social @scrippsocean.bsky.social

Thrilled to share this collaborative work by Kristie Yu, Francis Chandra, Amina Schartup and teams @Scripps_Ocean and @UCLA showing that an engineered gut bacterium can be used to reduce the neurotoxic effects of dietary methylmercury www.cell.com/cell-host-mi...

Curious about how the gut microbiome modulates the neurological health of pregnant women and their offspring? Check out my recent review with @pipethero.bsky.social out now @jclinical-invest.bsky.social! 🦠🤰👶🧠 www.jci.org/articles/vie...

Delighted to highlight new work by Kelly Jameson and colleagues showing that select microbial metabolites in the small intestinal lumen regulate vagal activity www.cell.com/iscience/ful...

Very happy to share new findings by Ezgi Özcan and colleagues showing that differences in fiber content in medical ketogenic diets can influence their anti-seizure effects! www.nature.com/articles/s41...

Now let me welcome @gdonaldson.bsky.social back to the wild wild West... We are excited to have you join our science family at UCLA #GoodmanLuskinMicrobiomeCenter. Lots more microbiome magic will be on the way! ✨

Happy to kick off 2025 with this new review on gut microbiota-neuroepithelial signaling by the very talented Taka Ohara!

It was an honor to highlight this fantastic work by Cheng and Venkatesh et al of the Gordon lab. Many thanks to them, and to Francis Chandra for doing all the heavy lifting on this Spotlight! @cp-cellchembiol.bsky.social

Delighted to share work by Kristie Yu, Celine Son, & co showing that selective fructan metabolism by the gut microbiome can contribute to host associative learning of dietary preference, even when it comes to choosing between diets with the same perceptual salience (and macronutrient composition!)