Stephanie Orchanian
@stephorch.bsky.social
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UCLA Chancellor’s Postdoctoral Fellow studying the maternal gut microbiome
reposted by
Stephanie Orchanian
Elaine Hsiao
about 2 months ago
Excited to share new work by Guli Agirman + co that identifies a direct mechanism linking gut microbial imidazole propionate to stress! 🧠🦠 Btw this image was made by Nano Banana Pro 🍌. First time I've gotten a model to accurately generate a science graphic 🤯
authors.elsevier.com/a/1mA5M6t8JE...
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Excited to share our recent publication in this month's issue of mBio, based on my PhD research. We show that replication of 𝘛. 𝘨𝘰𝘯𝘥𝘪𝘪 is required to trigger a localized immune response in the brain! 🧠
bit.ly/3TA9ALj
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Toxoplasma gondii parasites induce a localized myeloid cell immune response surrounding parasites in the brain during acute infection | mBio
Toxoplasma gondii is a brain-infecting parasite, and the mobilization of peripheral immune cells to the brain is critical for controlling T. gondii infection. However, the initial events driving these...
http://bit.ly/3TA9ALj
6 months ago
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reposted by
Stephanie Orchanian
Elaine Hsiao
9 months ago
Thrilled to share this collaborative work by Kristie Yu, Francis Chandra, Amina Schartup and teams @Scripps_Ocean and @UCLA showing that an engineered gut bacterium can be used to reduce the neurotoxic effects of dietary methylmercury
www.cell.com/cell-host-mi...
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An engineered gut bacterium protects against dietary methylmercury exposure in pregnant mice
Yu and Chandra et al. engineered a commensal gut microbe, Bacteroides thetaiotaomicron, to detoxify methylmercury (MeHg). The engineered bacterium reduces MeHg in the intestinal lumen, limits its accu...
https://www.cell.com/cell-host-microbe/abstract/S1931-3128(25)00142-8
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reposted by
Stephanie Orchanian
Journal of Clinical Investigation
11 months ago
Maternal microbiome is a cornerstone of maternal and fetal health.
https://buff.ly/431YoNu
@stephorch.bsky.social
&
@pipethero.bsky.social
highlight gut microbiome x environmental interactions at the maternal-fetal interface that influence the brains of pregnant people and developing offspring.
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Curious about how the gut microbiome modulates the neurological health of pregnant women and their offspring? Check out my recent review with
@pipethero.bsky.social
out now
@jclinical-invest.bsky.social
! 🦠🤰👶🧠
www.jci.org/articles/vie...
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JCI - The microbiome as a modulator of neurological health across the maternal-offspring interface
https://www.jci.org/articles/view/184314
11 months ago
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