Gregor Bond
@gregorbond.bsky.social
📤 639
📥 587
📝 104
transplant nephrologist and psychotherapy student in Vienna (Austria)
Join us Friday 7:15 CEST for best of
#ERA2026
@markusathome.bsky.social
to learn more about TTV-guided immunosuppression in kidney transplantation
#TTVguide
youtu.be/OxbYH9yOd6w?...
loading . . .
62nd ERA Congress - Profs. Segelmark, Willcocks, Dixon, Fervenza, Bond, Lambers Heerspink, Neuen
YouTube video by MARKUS at HOMe
https://youtu.be/OxbYH9yOd6w?si=4bzqVGYrXw8j4qWy
13 days ago
0
2
1
reposted by
Gregor Bond
MedUni Wien
14 days ago
📢
#Bildung
ist Zukunft. Darum braucht es starke Universitäten — und keine Kürzungen bei Wissenschaft und Forschung. Mit der Petition
#unisretten
wird ein klares Zeichen gegen den geplanten Sparkurs gesetzt. ✍️ Jetzt unterstützen! ⬇️
loading . . .
Jetzt unterzeichnen: #unisretten
Zur Petition!
https://mein.aufstehn.at/petitions/unisretten-keine-kurzungen-bei-den-universitaten
1
7
5
reposted by
Gregor Bond
MedUni Wien
16 days ago
Successful trial ✅️ An international team coordinated by #MedUniVienna demonstrated in a #clinicaltrial that #TorqueTenovirus-guided dosing of #immunosuppressants in #kidneytransplant recipients is safe. More about the
@ttvguidetx.bsky.social
study coordinated by
@gregorbond.bsky.social
! ⬇️
loading . . .
Biomarker-guided immunosuppression following kidney transplantation successfully tested
Further details!
https://www.meduniwien.ac.at/web/en/about-us/news/2026/news-in-june-2026/biomarker-guided-immunosuppression-following-kidney-transplantation-successfully-tested/
0
15
5
first data of the TTVguideIT RCT presented by
@fredhaupenthal.bsky.social
at ERA26 in Glasgow Torque Teno 🦠 virus guided immunosuppression 💊 is safe in kidney TX and might help reducing TAC dose
#TTVguide
18 days ago
0
9
3
First data of the TTVguideIT RCT presented @ERA26 in Glasgow 🏴 Personalized Immunosuppression 💊 by Torque Teno 🦠 virus in kidney TX is safe and might help reducing Tacrolimus
#TTVguide
@fredhaupenthal.bsky.social
👏
19 days ago
0
8
5
the TTVguideTX team @research night for the public
@meduniwien.ac.at
Vienna - Austria all age groups were welcome to learn about science we presented the principle of TTV-guided immunosuppression
#TTVguide
about 2 months ago
0
3
1
Felix Herkner communicates the potential of TT virus 🦠 guided Immunosuppression to the Austrian 🇦🇹 public
#TTVguide
2 months ago
0
2
0
It would be great to see you Friday night this week @ researchers night
@meduniwien.ac.at
learn how the TT virus can be used as Immunometer kids are very welcome
#TTVguide
langenachtderforschung.at/station/6326
loading . . .
Viren können Superheroes sein oder wie kann man das Immunsystem messen? - #LNF26 Lange Nacht der Forschung
Wir erforschen wie man die Stärke des Immunsystems messen kann. Zuerst erklären wir Ihnen, anhand eines Posters und eines Animationsfilms wie das funktioniert und warum uns das TT Virus dabei hilft. D...
https://langenachtderforschung.at/station/6326
2 months ago
0
2
0
Torque Teno virus 🦠 predicts malignancy post kidney transplant
#TTVguide
2 months ago
0
2
0
clinical trial simulations to optimise analysis strategies for multiple endpoints highlight the trade-off between statistical efficiency and interpretability
#ttvguide
www.nature.com/articles/s41...
loading . . .
Comparison of primary analysis strategies of randomized controlled trials with multiple endpoints with application to kidney transplantation - Scientific Reports
Scientific Reports - Comparison of primary analysis strategies of randomized controlled trials with multiple endpoints with application to kidney transplantation
https://www.nature.com/articles/s41598-026-38979-6
4 months ago
0
1
1
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
5 months ago
Remember the TOPCAT story of what happened in Russia and Georgia? This is worse:
www.science.org/content/blog...
And in South Florida. From
@dereklowe.bsky.social
1
18
10
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
6 months ago
Should we be treating inpatient hypertension? Interesting case with two discussants (Michael Rothberg vs Tara Chang)
www.nejm.org/doi/full/10....
I have to confess despite being a nihilist for treating inpatient BP I am tempted to do something in this setting.
1
11
4
no screening in Austria 🇦🇹 😥
add a skeleton here at some point
7 months ago
0
1
0
Torque Teno Virus 🦠 ads to SOC to predict BK viraemia 🦠 can be 🦸♀️
#ttvguide
www.sciencedirect.com/science/arti...
loading . . .
Predictive Value of TTV Viral Load for BKPyV DNAemia Depends on BKPyV-Specific Humoral Immunity in KTRs
Neutralizing antibodies (NAbs) have been proposed as biomarkers for stratifying BKPyV replication risk, while TTV viral load is recognized as a global…
https://www.sciencedirect.com/science/article/abs/pii/S1600613525030710
7 months ago
0
4
0
thanks 🙏 BTS for the invitation! what a warm welcome to london 🇬🇧 I guess DSA, GEP, ddcfDNA and TTV will nicely come together as comprehensive immune monitoring post SOT
bts.org.uk/bts-autumn-s...
#TTVguide
loading . . .
BTS Autumn Symposium - British Transplantation Society
The Fundamentals of Transplantation: A Joint Educational Event by The Herrick Society of Trainees in Transplant Surgery & The British Transplant Physician Trainees
https://bts.org.uk/bts-autumn-symposia/
7 months ago
0
2
0
Immune Monitoring Goes Viral 🦠 Torque Teno Virus for Immunologic Risk Stratification After Kidney Transplantation ⏩️ new review in TI 🔥
doi.org/10.3389/ti.2...
#ttvguide
7 months ago
0
4
2
the cure for kidney week FOMO 😀
www.nephjc.com/news/kidneyw...
loading . . .
Kidney Week in Houston: Day 1 — NephJC
in this edition: Atacicept in IgAN; Albuminuria as a surrogate outcome, Renal Remission and additional CONFIDENCE analysis
http://www.nephjc.com/news/kidneywk25-day1
7 months ago
0
3
1
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
The second sibeprenlimab paper in
@nejm.org
(At least we gave it an oral at
#KidneyWk
unlike the poster for the phase 2 data in 2023!)
www.nejm.org/doi/full/10....
loading . . .
Sibeprenlimab in IgA Nephropathy — Interim Analysis of a Phase 3 Trial | NEJM
The cytokine A proliferation-inducing ligand (APRIL) is considered a key driver of the pathogenesis of IgA nephropathy. Sibeprenlimab, a humanized IgG2 monoclonal antibody, selectively binds to and...
https://www.nejm.org/doi/full/10.1056/NEJMoa2512133?query=RP&ssotoken=U2FsdGVkX18HwtSgXglJ1gbcCroISBKK7yPln43pSCZV8yPfQWUatNAzAHDZBaHCcgLB1ey0WaqsHwg9PzlzebfiBSX0qqNhK5vqLkva1kwLqzfHXq6r3A1Q2ZJqPOKnmHuZ7VTxPnkrt%2FDjX5BImxr3NHKvBalst0pzallnX5zWjaTtwNLPxgJ7wITboUre4GGzki3ZPnqTE%2BULAIOe5mWs5ItpHCKC8AWsoKuDhtE%3D&cid=NEJM%20Recently%20Published,%20November%208,%202025%20DM2425300_NEJM_Non_Subscriber&bid=-1078256474
1
12
5
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
And another ns-MRA Balcinrenone added to Dapa in proteinuric CKD
#KidneyWK
@thelancet.com
www.thelancet.com/journals/lan...
loading . . .
Balcinrenone in combination with dapagliflozin compared with dapagliflozin alone in patients with chronic kidney disease and albuminuria: a randomised, active-controlled double-blind, phase 2b clinica...
In participants with chronic kidney disease at increased risk of disease progression, a fixed dose combination of balcinrenone and dapagliflozin was superior to dapagliflozin alone in reducing albumin...
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02014-8/abstract
0
12
7
reposted by
Gregor Bond
NEJM.org
8 months ago
ORIGIN phase 3 trial: In an interim analysis of a clinical trial, atacicept, a fusion protein that binds and inhibits two cytokines thought to be central to the pathophysiology of IgA nephropathy, significantly reduced proteinuria.
nej.md/3JEq8QL
@asnkidney.bsky.social
|
#KidneyWk
0
19
10
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
Eli Lilly continuing to hit it out the park Selective amylin agonist as an alternative to GLP1RAs?
#eloralintide
www.thelancet.com/journals/lan...
in
@thelancet.com
(Yeah I know it’s
#KidneyWk
but what do we do till Houston wakes up!) cc
@rnflex.bsky.social
0
10
4
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
Another simultaneous publication from the afternoon session Albuminuria as an acceptable surrogate outcome (per our discussion earlier today)
www.nature.com/articles/s41...
in
@naturemedicine.bsky.social
@nature.com
sadly paywalled
#KidneyWk
loading . . .
A meta-analysis of albuminuria as a surrogate endpoint for kidney failure - Nature Medicine
In a meta-analysis of 48 randomized trials of chronic kidney disease progression, reduction in the 6-month urinary albumin:creatinine ratio was associated with lower hazard ratios of established kidne...
https://www.nature.com/articles/s41591-025-04057-z
0
8
4
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
a conservative dialysis strategy in possibly recovering AKI helps people recover faster!
jamanetwork.com/journals/jam...
in
@jama.com
from
#KidneyWk
Like STARRT-AKi et al, at the other end? Small trial - needs replication or this is common sense?
loading . . .
A Conservative Dialysis Strategy and Kidney Function Recovery in Dialysis-Requiring Acute Kidney Injury
This trial examines whether a conservative dialysis strategy can improve recovery of kidney function for patients with acute kidney injury who require dialysis.
https://jamanetwork.com/journals/jama/fullarticle/2841171
1
9
4
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
low dose Tac + Everolimus is not superior to Tac + MMF in older transplant recipients in
@asnpublications.bsky.social
another LBCT from
#KidneyWk
published
journals.lww.com/jasn/fulltex...
loading . . .
https://journals.lww.com/jasn/fulltext/9900/immunosuppression_in_older_kidney_transplant.821.aspx
0
5
1
jamesstein18.substack.com/p/my-hot-tak...
loading . . .
My Hot Take on PISCES, the New Fish Oil in Hemodialysis Study
I love when a new study challenges what we think we know.
https://jamesstein18.substack.com/p/my-hot-take-on-pisces-the-new-fish
7 months ago
0
0
0
😲 too good to be true? nothing except tx reduces death on hd and now…. something safe, cheep and with more effect than tx (and more effect than in non hd) waiting for the
@freelyfiltered.bsky.social
podcast covering this paper
www.nejm.org/doi/full/10....
loading . . .
Fish-Oil Supplementation and Cardiovascular Events in Patients Receiving Hemodialysis | NEJM
Cardiovascular disease is the leading cause of death in patients receiving hemodialysis, yet effective preventive therapies remain limited. Supplementation with n−3 polyunsaturated fatty acids, esp...
https://www.nejm.org/doi/full/10.1056/NEJMoa2513032
7 months ago
0
1
0
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
Natural history of RRT from the ERA registry The visual abstract in this case tells a lot
academic.oup.com/ndt/advance-...
@ndt-era.bsky.social
#NephSky
2
9
2
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
Should we be screening every young child’s urine (as is done in some countries!)
@rheaultm.bsky.social
and Oliver Gross make the case in
@kireports.bsky.social
www.kireports.org/article/S246...
Main issue: we have therapeutic options!
#NephSky
loading . . .
Urine screening to early diagnose young individuals with CKD: a call for action
Alport syndrome is an inherited disorder of basement membranes leading to progressive chronic kidney disease, hearing loss, and ocular abnormalities in many affected patients. When the authors started...
https://www.kireports.org/article/S2468-0249(25)00658-8/fulltext?rss=yes
4
15
5
can viruses 🦠 be superheroes 🦸♂️ ? PhD student Felix Herkner just published the statistical analysis plan of the TTVguideIT trial 💪👏 Torque Teno virus guided immunosuppression
#TTVguide
data cleaning until Q1/26 analysis Q2/26
trialsjournal.biomedcentral.com/articles/10....
loading . . .
Statistical analysis plan for TTVguideIT—a multicentre, patient- and assessor-blinded, non-inferiority, randomised and controlled phase II trial to compare standard and Torque Teno virus-guided immuno...
Background Non-interventional studies indicate an association between Torque Teno Virus (TTV) load in peripheral blood and immunosuppression related outcomes in kidney transplant recipients. This make...
https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-025-09119-8
8 months ago
0
3
2
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
As expected, Iptacopan phase 3 in IgA nephropathy slows GFR decline APPLAUSE-IgA Adding another new medication we won’t be able to access or afford to our IgA armamentarium
#NephSky
www.novartis.com/news/media-r...
loading . . .
Novartis Fabhalta® (iptacopan) meets Phase III primary endpoint, slows kidney function decline in patients with IgA nephropathy (IgAN)
https://www.novartis.com/news/media-releases/novartis-fabhalta-iptacopan-meets-phase-iii-primary-endpoint-slows-kidney-function-decline-patients-iga-nephropathy-igan
3
21
7
reposted by
Gregor Bond
Swapnil Hiremath 🍁🇨🇦
8 months ago
Big win for telitacicept in SLE (not lupus nephritis, yet)
www.nejm.org/doi/full/10....
BAFF + APRIL FTW
#nephSky
#Lupus
loading . . .
A Phase 3 Trial of Telitacicept for Systemic Lupus Erythematosus | NEJM
Telitacicept, a new dual inhibitor of the cytokines B-lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligand), showed efficacy in adults with active systemic lupus erythematosus (S...
https://www.nejm.org/doi/full/10.1056/NEJMoa2414719
0
10
3
viruses 🦠 can be superheroes 🦸♀️ Felix Herkner present the statistical analysis plan of the TTVguideIT trial at the Austrian Transplant Congress Torque Teni Virus guided immunosuppression
#TTVguide
8 months ago
1
2
0
happy to speak about TT virus 🦠 @Italien 🇮🇹 micro biology congress TTV based immune monotoring
#TTVguide
9 months ago
0
4
1
mhm that makes me curiouse to have a look at the calculations of the DSMB that led to the termination of the trial; must have been a tought decision
add a skeleton here at some point
10 months ago
0
1
0
well written; as a kidney doc I would just not agree that protein is bad for your kidneys
add a skeleton here at some point
10 months ago
0
4
1
10 months ago
0
2
0
>7.000 kidney transplant recipients on SGLT2 inhibitors & GLP-1RAs ▶️ better survival, cardiovascular & kidney outcomes, weight loss, lower HbA1c no safety risks
tinyurl.com/4p6fdybn
loading . . .
SGLT2 Inhibitors and GLP-1 Receptor Agonists in Kidney... : Transplantation
ovascular and kidney benefits in non-KT recipients, but evidence in KT recipients remains limited. This systematic review and meta-analysis provide updated evidence on the efficacy and safety of SGLT2...
https://tinyurl.com/4p6fdybn
10 months ago
0
5
1
reposted by
Gregor Bond
Joel Topf
11 months ago
I use a cool programmable calculator called Soulver that works on and syncs across my iPhone, iPad, and Mac. I just created a formula to calculate the sodium after any combination of IV fluids and urine output based on Edelman.
3
15
2
reposted by
Gregor Bond
TTVguideTX
11 months ago
Last week, our team around
@gregorbond.bsky.social
from
@meduniwien.ac.at
took part in the "Kinderuni Wien" - Vienna’s Children’s University - to bring science to life for curious kids aged 7 to 12, where the kids learnt that some viruses like TTV can also be superheroes.
#TTVguide
add a skeleton here at some point
0
3
2
I had great fun at kids university
@meduniwien.ac.at
today 😁 viruses 🦠 can be superheroes 🦸♀️ 🙏
@sebastiankaps.bsky.social
and
@fredhaupenthal.bsky.social
for your support
#ttvguide
11 months ago
1
5
1
reposted by
Gregor Bond
TTVguideTX
12 months ago
Our team around
@gregorbond.bsky.social
recently participated at
#ESOT2025
- here's our most important learnings: 🔸 More & more groups worldwide pick up the idea of TTV-guided immunosuppression. 🔸 First data on the association between TTV load & the development of malignomes is available.
#ttvguide
0
4
2
the highly prevalent and apathogenic TorqueTeno virus 🦠 is associated with immunosuppression 💊 Carsten Herz presents first data on the predicive value of malignancy post kidney transplant
#TTVguide
12 months ago
0
2
1
#ESOTCongress
London 🇬🇧 Action at the eposters a multicenter observational study to validate the value of proteinuria for assessment of kidney graft quality
12 months ago
0
4
2
#ESOTCongress
2025 London 🇬🇧 action at the eposters Torque Teno virus 🦠 for the prediction of Infection post kidney TX first long term data
#TTVguide
12 months ago
1
5
3
#ESOTCongress
London 🇬🇧 presidents dinner ☺️
12 months ago
0
2
2
freddi at
#ESOTcongress
🇬🇧 depression is a major factor for reduced HRQOL post kidney TX
@fredhaupenthal.bsky.social
12 months ago
0
3
1
happy 😊 meeting you @
#ESOTcongress
this Monday 1.7. in London 🇬🇧 talks 🗣️ on Torque Teno virus 🦠 guided immunosuppression 💊 09:30 and 11:00 room S1 13:15 room S5, 16:15 room S4
#ttvguide
12 months ago
0
4
2
meet me at
#ESOTcongress
in London 🇬🇧 🗓️ July 1, 13:00-14:00, ROOM s5 to discuss Torque Teno virus 🦠 based immunologic monotoring viruses 🦠 can be superheroes 🦸
#ESOT2025
#TTVguide
#ESOT
about 1 year ago
0
2
2
this will be fun!
#TTVguide
add a skeleton here at some point
about 1 year ago
0
0
0
Load more
feeds!
log in