Gregor Bond
@gregorbond.bsky.social
๐ค 622
๐ฅ 575
๐ 80
transplant nephrologist and psychotherapy student in Vienna (Austria)
happy to speak about TT virus ๐ฆ @Italien ๐ฎ๐น micro biology congress TTV based immune monotoring
#TTVguide
18 days ago
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mhm that makes me curiouse to have a look at the calculations of the DSMB that led to the termination of the trial; must have been a tought decision
add a skeleton here at some point
about 1 month ago
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well written; as a kidney doc I would just not agree that protein is bad for your kidneys
add a skeleton here at some point
about 1 month ago
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about 2 months ago
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>7.000 kidney transplant recipients on SGLT2 inhibitors & GLP-1RAs โถ๏ธ better survival, cardiovascular & kidney outcomes, weight loss, lower HbA1c no safety risks
tinyurl.com/4p6fdybn
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SGLT2 Inhibitors and GLP-1 Receptor Agonists in Kidney... : Transplantation
ovascular and kidney benefits in non-KT recipients, but evidence in KT recipients remains limited. This systematic review and meta-analysis provide updated evidence on the efficacy and safety of SGLT2...
https://tinyurl.com/4p6fdybn
about 2 months ago
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reposted by
Gregor Bond
Joel Topf
3 months ago
I use a cool programmable calculator called Soulver that works on and syncs across my iPhone, iPad, and Mac. I just created a formula to calculate the sodium after any combination of IV fluids and urine output based on Edelman.
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reposted by
Gregor Bond
TTVguideTX
3 months ago
Last week, our team around
@gregorbond.bsky.social
from
@meduniwien.ac.at
took part in the "Kinderuni Wien" - Viennaโs Childrenโs University - to bring science to life for curious kids aged 7 to 12, where the kids learnt that some viruses like TTV can also be superheroes.
#TTVguide
add a skeleton here at some point
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I had great fun at kids university
@meduniwien.ac.at
today ๐ viruses ๐ฆ can be superheroes ๐ฆธโโ๏ธ ๐
@sebastiankaps.bsky.social
and
@fredhaupenthal.bsky.social
for your support
#ttvguide
3 months ago
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reposted by
Gregor Bond
TTVguideTX
3 months ago
Our team around
@gregorbond.bsky.social
recently participated at
#ESOT2025
- here's our most important learnings: ๐ธ More & more groups worldwide pick up the idea of TTV-guided immunosuppression. ๐ธ First data on the association between TTV load & the development of malignomes is available.
#ttvguide
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the highly prevalent and apathogenic TorqueTeno virus ๐ฆ is associated with immunosuppression ๐ Carsten Herz presents first data on the predicive value of malignancy post kidney transplant
#TTVguide
3 months ago
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#ESOTCongress
London ๐ฌ๐ง Action at the eposters a multicenter observational study to validate the value of proteinuria for assessment of kidney graft quality
3 months ago
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#ESOTCongress
2025 London ๐ฌ๐ง action at the eposters Torque Teno virus ๐ฆ for the prediction of Infection post kidney TX first long term data
#TTVguide
3 months ago
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#ESOTCongress
London ๐ฌ๐ง presidents dinner โบ๏ธ
3 months ago
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freddi at
#ESOTcongress
๐ฌ๐ง depression is a major factor for reduced HRQOL post kidney TX
@fredhaupenthal.bsky.social
3 months ago
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happy ๐ meeting you @
#ESOTcongress
this Monday 1.7. in London ๐ฌ๐ง talks ๐ฃ๏ธ on Torque Teno virus ๐ฆ guided immunosuppression ๐ 09:30 and 11:00 room S1 13:15 room S5, 16:15 room S4
#ttvguide
3 months ago
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meet me at
#ESOTcongress
in London ๐ฌ๐ง ๐๏ธ July 1, 13:00-14:00, ROOM s5 to discuss Torque Teno virus ๐ฆ based immunologic monotoring viruses ๐ฆ can be superheroes ๐ฆธ
#ESOT2025
#TTVguide
#ESOT
4 months ago
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this will be fun!
#TTVguide
add a skeleton here at some point
4 months ago
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congrets to Katharina Mayer receiving the young investigator award @
#ERA25
๐ how do TX baseline and fup data influence TT virus ๐ฆ load?
#TTVguide
4 months ago
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torque teno virus ๐ฆ load predicts malignoma post kidney TX ๐ช ๐ carsten herz at
#era25
viruses ๐ฆ can be ๐ฆธ superheros TTVbased immune monitoring
#TTVguide
4 months ago
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Sebastian Kapps presents first data on Torque Teno virus ๐ฆ in long-term kidney TX patients at
#ERA25
#TTVguide
4 months ago
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#TTVguide
๐ช
add a skeleton here at some point
4 months ago
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reposted by
Gregor Bond
Swapnil Hiremath ๐๐จ๐ฆ
4 months ago
The first
#ERA25
simultaneous pub CONFIDENCE trial of empagliflozin + finerenone in N = 579 Greater reduction in ACR and BP Note the impressive GFR dip
www.nejm.org/doi/full/10....
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full engangement on our โyear 4โ TTVguideTX project meeting ๐ช viruses ๐ฆ can be superheros ๐ฆธโโ๏ธ
#TTVguide
4 months ago
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reposted by
Gregor Bond
Joel Topf
4 months ago
This was a fun article to work on. Hope you enjoy it. Things We Do for No Reasonโข: Avoiding IV iodinated contrast material in patients with acute kidney injury or chronic kidney disease Journal of Hospital Medicine
shmpublications.onlinelibrary.wiley.com/doi/10.1002/...
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Things We Do for No Reasonโข: Avoiding intravenous iodinated contrast material in patients with acute kidney injury or chronic kidney disease
Click on the article title to read more.
https://shmpublications.onlinelibrary.wiley.com/doi/10.1002/jhm.70063
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we did it ๐๐พ๐๐บ๐โบ๏ธ today was last visit of the last patient of the TTVguideIT study 260 KTX recipients randomiced to torque teno virus ๐ฆ guided immunosuppression vs SOC and followed for one year thanks to all 13 recruiting centers across europe
#ttvguide
5 months ago
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@fredhaupenthal.bsky.social
add a skeleton here at some point
5 months ago
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reposted by
Gregor Bond
NDT
5 months ago
Self-reported non-adherence to immunosuppressive medication detected by the BAASIS predicts allograft rejections in kidney transplant recipients
doi.org/10.1093/ndt/...
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Sebastian Kapps taking science ๐งฌ to the public ๐จ๐ฝโ๐ฆฑ๐ฉ๐พ๐จ๐ผโ๐ฆฒ๐ต๐ผ can we use a virus ๐ฆ to quantify the immune system?
#ttvguide
5 months ago
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the BAASIS - a simple self assessement tool - predicts clinically relevant non-adherence in kidney TX patients
academic.oup.com/ndt/advance-...
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Self-reported Non-adherence to Immunosuppressive Medication Detected by the BAASIS Predicts Allograft Rejections in Kidney Transplant Recipients
AbstractBackground. After kidney transplantation adherence to immunosuppressive medication is crucial for graft survival and its assessment requires valid
https://academic.oup.com/ndt/advance-article/doi/10.1093/ndt/gfaf078/8121407
5 months ago
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reposted by
Gregor Bond
TTVguideTX
6 months ago
Watch
@fredhaupenthal.bsky.social
-
#TTVguide
investigator from
@meduniwien.ac.at
presenting first data from the AdTorque trial: self-reported non-adherence by the BAASIS predicts graft rejection
oup.cloud.panopto.eu/Panopto/Page...
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Self-reported Non-adherence to Immunosuppressive Medication Detected by the BAASIS Predicts Allograft Rejections in Kidney Transplant Recipients
Presented by Gregor Bond Article DOI:
https://oup.cloud.panopto.eu/Panopto/Pages/Viewer.aspx?id=edf1261a-7b67-4aeb-9d4d-b2bc011ef167
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reposted by
Gregor Bond
Nephrology Times
6 months ago
Is metformin use ever appropriate for patients with advanced kidney disease and type 2 diabetes?
#nephrology
#nephsky
#kidneydisease
#diabetes
#metformin
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Continuing Versus Stopping Metformin Use in Advanced CKD | Docwire News
A study examined mortality and MACE outcomes with metformin use for patients with advanced kidney disease and type 2 diabetes.
https://www.docwirenews.com/post/continuing-versus-stopping-metformin-use-in-advanced-ckd
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very important study for clinical trial design!!
add a skeleton here at some point
7 months ago
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this might change nephrology ๐ค
academic.oup.com/ndt/advance-...
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Rationale and design of the Renal Lifecycle Trial assessing the Effect of Dapagliflozin on Cardiorenal Outcomes in Severe Chronic Kidney Disease
AbstractBackground. Several clinical trials have shown beneficial effects of sodium-glucose co-transporter 2 (SGLT2) inhibitors on kidney disease progressi
https://academic.oup.com/ndt/advance-article/doi/10.1093/ndt/gfaf046/8063579
7 months ago
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big news on torque teno virus ๐ฆ guided immunosuppression this summer in London ๐ด๓ ง๓ ข๓ ฅ๓ ฎ๓ ง๓ ฟ at the EU Transplant Congress
#TTVguide
#ESOTcongress
add a skeleton here at some point
7 months ago
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my thoughts are with texan parents of children suffering from measls ๐ฆ ignorance towards science ๐งฌ can cause terrible pain ๐ข while hiding wellโฆtruth does exist vaccination ๐ does work and safes lifes ๐
7 months ago
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๐ฎ Kidney transplant recipients with GLP-1 RA โก๏ธ 49% lower graft loss โก๏ธ 31% lower mortality real-world retrospective study of 18,106 KTX with diabetes
www.sciencedirect.com/science/arti...
7 months ago
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comprehensive review on TTV by our project partners in Rome ๐ฎ๐น ubiquitouse and non- pathogenic Torque Teno virus ๐ฆ TTV might act as immunometer or vector ๐ช
#ttvguide
www.mdpi.com/1999-4915/17...
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Torque Teno Virus: Lights and Shades
Torque Teno Virus (TTV) is a highly prevalent non-pathogenic DNA virus whose plasma levels may be related to the hostโs immune status. TTV gained attention about 25 years ago, but its replication is n...
https://www.mdpi.com/1999-4915/17/3/334
7 months ago
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we are proud to be part of the OEAD science ambassador team visiting school kids in vienna ๐ฆ๐น bringing science closer to young minds ๐งฌ โก๏ธ ๐ซ ๐ง ๐ฆ
@oeadcitizenscience.bsky.social
#ttvguide
youngscience.oead.at/de/wissensch...
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Botschafter/innen-Profile
https://youngscience.oead.at/de/wissenschaftsvermittlung/wissenschaftsbotschafter-innen/botschafter-profile/668
7 months ago
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#ttvguide
@ttvguidetx.bsky.social
add a skeleton here at some point
7 months ago
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might TTMD and TTM virus ๐ฆ complement TT virus guided immune monitoring? ๐งฌ๐ great work from Rome ๐ฎ๐น
#ttvguide
www.mdpi.com/1422-0067/26...
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Assessment of Torquetenominivirus (TTMV) and Torquetenomidivirus (TTMDV) as Complementary Biomarkers to Torquetenovirus (TTV)
Recent studies have identified Torquetenovirus (TTV) as a promising biomarker of immune competence, particularly in assessing the vaccine response of solid organ transplant (SOT) recipients. However, ...
https://www.mdpi.com/1422-0067/26/3/1022
8 months ago
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reposted by
Gregor Bond
Swapnil Hiremath ๐๐จ๐ฆ
8 months ago
Our last
#ISNWCN
debate on protein restriction in CKD is now published -
#OpenAccess
pubmed.ncbi.nlm.nih.gov/39933007/
with
@kidneyboy.bsky.social
and Abdullah Bawazir, OttawaRenal fellow
#NephSky
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Protein restriction in CKD: an outdated strategy in the modern era - PubMed
Chronic kidney disease (CKD) management has traditionally emphasized dietary protein restriction to slow disease progression and delay end-stage renal disease (ESRD). However, evidence from trials que...
https://pubmed.ncbi.nlm.nih.gov/39933007/?utm_source=Feedly&utm_medium=rss&utm_content=1TOjW_LBRK9WqwsAtrQ2wD4TTrl162p5k4buDZNj8rNd22kgk8&ff=20250211220206&v=2.18.0.post9+e462414
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#TTVguide
add a skeleton here at some point
8 months ago
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reposted by
Gregor Bond
NEJM.org
8 months ago
In the REGENCY trial, obinutuzumab, a humanized type II anti-CD20 monoclonal antibody, plus standard therapy provided significantly better renal responses than standard therapy alone in patients with lupus nephritis. Full trial results:
nej.md/3Eq6gxV
#ISNWCN
|
@theisn.org
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Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis | NEJM
Obinutuzumab, a humanized type II anti-CD20 monoclonal antibody, provided significantly better renal responses than placebo in a phase 2 trial involving patients with lupus nephritis receiving stan...
https://nej.md/3Eq6gxV
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reposted by
Gregor Bond
Swapnil Hiremath ๐๐จ๐ฆ
8 months ago
Also published today The Boston first in human kidney xenotransplantation case report
@nejm.org
#ISNWCN
www.nejm.org/doi/full/10....
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reposted by
Gregor Bond
Joel Topf
8 months ago
Omg omg omg
www.kidneyfund.org/article/fda-...
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FDA greenlights first clinical trials for genetically modified pig kidney transplants in humans
Two companies have received FDA approval to conduct clinical trials transplanting genetically modified pig kidneys into patients with kidney failure
https://www.kidneyfund.org/article/fda-greenlights-first-clinical-trials-genetically-modified-pig-kidney-transplants-humans
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interested in personalized immunosuppression? ๐ ๐ ๐ join my webinar on Torque Teno Virus ๐ฆ based immune monitoring ๐๏ธ 12 FEB 2025 | 2-3p CST
attendee.gotowebinar.com/register/755...
#ttvguide
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https://attendee.gotowebinar.com/register/7558751459503756890?source=Gbond
8 months ago
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effects of iron ๐ฉธ therapy on clinical outcomes in chronic kidney disease analyzing 45 randomized trials
8 months ago
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reposted by
Gregor Bond
Prof Claire Hills
8 months ago
๐ฃ Semaglutide in patients with overweight or obesity and chronic kidney disease without diabetes: a randomized double-blind placebo-clinical trial
@naturemedicine.bsky.social
๐ฉโ๐ฌ๐ฅผ๐งช๐จโ๐ฌ
#Semaglutide
#KidneyDisease
#Obesity
#kidney
#NephroSky
#CardioSky
#NephSky
๐๐๐
pubmed.ncbi.nlm.nih.gov/39455729/
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Semaglutide in patients with overweight or obesity and chronic kidney disease without diabetes: a randomized double-blind placebo-controlled clinical trial - PubMed
Semaglutide reduces albuminuria and the risk of kidney disease progression in patients with type 2 diabetes and chronic kidney disease (CKD). We conducted a randomized placebo-controlled double-blind ...
https://pubmed.ncbi.nlm.nih.gov/39455729/
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reposted by
Gregor Bond
Nephrology Times
8 months ago
โ ๏ธ The FDA has approved Ozempic for use in kidney disease.
#nephrology
#nephsky
#kidneydisease
#diabetes
#ozempic
#semaglutide
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FDA Approves Ozempic for Kidney Disease | Docwire News
Based on FLOW trial results, the FDA has approved Ozempic (semaglutide) to treat chronic kidney disease (CKD) in adults with type 2 diabetes.
https://buff.ly/3PUZSBm
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reposted by
Gregor Bond
Joel Topf
9 months ago
From my fellow
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