🧠Pain sensors need to switch on fast—and off just as quickly. In our new tour de force Nat Comms paper - led by the first Paulsen lab grad student - we show that calmodulin plays a key role in shutting down the TRPA1 pain receptor - a finding that could guide new pain therapies. 📰 rdcu.be/eJcMK

Thank you to everyone who attended this year’s retreat at the Heritage Hotel. A special thank you to retreat coordinators Enrique De La Cruz, Rachel Agosto, and Liz Vellali!

Malvankar lab publishes pioneer research delving into the quantum mechanics underlying bacterial respiration mbb.yale.edu/news/malvank...

Ailong Ke Leads Study Revealing Hidden RNA‑Editing Activity in CRISPR‑Cas9 www.cell.com/cell/fulltex...

Heffler and @LammerdingLab.bsky.social discuss recent studies from the @schliekerlab.bsky.social (doi.org/10.1083/jcb....) and @hennelab.bsky.social (doi.org/10.1016/j.ce...) that identify two proteins serving as crucial mechanical elements in the endoplasmic reticulum. rupress.org/jcb/article/...

Congratulations to Enrique M. De La Cruz for his election as President of the Biophysics Society! mbb.yale.edu/news/congrat...

🔬 Join us LIVE on Zoom this Wednesday, June 11, at 4 PM ET! We’re excited to co-host the RNA Collaborative Seminar Series featuring 🎙️ Dr. @siggyn5.bsky.social (Yale RNA Center) 🎙️ Dr. Alex Wesselhoeft (HMS Initiative for RNA Medicine) Registration 👉 lnkd.in/e-9Huhzd

🧬 June RNA Club at Yale 📅 Tuesday, June 10th, 2025 📍 Location: Bass Center 305, Yale Science Building (Science Hill) This month’s speakers: 🔹 Dr. Chengtao Xu (Ke Lab) 🔹 Dr. Jyotsna Kumar (Garg Lab) 📣 Come for the science—stay for the conversations!

We’ve pioneered a disease-agnostic screening platform for aberrant biomolecular condensates—cellular structures linked to incurable neurological diseases. We screened genes and FDA-approved drugs that modulate disease-relevant nuclear condensates: www.biorxiv.org/cgi/content/...

Join us next week for MB&B's Computational Biophysics & Biochemistry Symposium on 6/17 in Bass 305!

we are beyond proud that our @yalembb.bsky.social @schliekerlab.bsky.social undergraduate researcher Sophia graduated as the sole @Yale Colleague '25 graduate with an exceptional distinction in the major! Congrats Sophia for this richly deserved honor!

Join our department as a Lecturer! Apply here: apply.interfolio.com/163609.

A useful tool and a great thing to do... 5calls.org/issue/nih-ns...

📣 New work from MB&B graduate student Max Paul, published in PNAS, reveals how a conserved region of the RasGAP C2 domain enhances enzymatic activity via allosteric interaction with Ras. Structural & functional data suggest a key role in Ras regulation! 🧫🔬 mbb.yale.edu/news/mbb-gra...

We are excited to announce a tenure-track or tenured faculty position in Computational Biophysics and Biochemistry, exploring the intricate molecular and cellular processes and the complex interactions of their macromolecular components. Join us in MB&B! Apply now at apply.interfolio.com/162132