Special Section in GBE: Structural Phylogenetics Here we showcase novel work on how 3D protein structures can reshape evolutionary biology, from methods to applications. More papers coming out soon! @genomebiolevol.bsky.social @proteinmechanic.bsky.social academic.oup.com/gbe/search-r...

Third Era of Phylogenetics! 1️⃣ Era 1: Morphology 🦴 2️⃣ Era 2: Sequences 🧬 3️⃣ Era 3: 3D Structures ⚛️ Solving deep evolutionary puzzles like never before. Our new review in GBE explores what's next in #phylogenetics academic.oup.com/gbe/article/... #structuralbiology #evolution #AlphaFold #SciSky

Quantome: A Quantum Surrogate Model for Biophysical Landscapes https://www.biorxiv.org/content/10.1101/2025.08.06.668871v1

Quantome: A Quantum Surrogate Model for Biophysical Landscapes https://www.biorxiv.org/content/10.1101/2025.08.06.668871v1

Playing around with quantum-styled math on trivial biological problems before tackling the really hard questions. Initial signs are good, with the math behaving as expected. Next leg would be using a non-trivial dataset like missense variants.

Within Tagetes lemmonii, (Lemmon’s marigold) are defence molecules called thiophenes which become highly toxic when exposed to sunlight, damaging pests at the cellular level. An elegant example of how plants weaponize light to survive. #Brisbane #nature #nikon #naturephotography #SciComm

If you do deep evolutionary analysis - structure-aware characters can help. To ensure correct alignments - give it a try: biosig.lab.uq.edu.au/structome_al... If you would like any features added, drop a message and will give it a shot. #Science #Evolution #MolecularEvolution #DeepEvolution

🧵: It's out. Structome-AlignViewer, a web-based resource for evaluating protein structure-aware sequence alignments. It maps alignment columns directly onto structures and helps identify conserved regions. Feedback encouraged. www.biorxiv.org/content/10.1... #Evolution #MolecularEvolution #Science

In a talk today thinking that science isn’t just a collection of facts it’s a method and sometimes, a philosophical tightrope. Emeritus Professor Ross Bernard at #UQ exploring how science proceeds - via falsifiability. Not everyone agrees but a conversation worth having. #Science #Philosophy

I am speaking soon about #Evolution at a public talk series in #Brisbane (Ticket $10). Many other talks covering a range of topics. Interested in havin a fun science evening with family? For more information vIsit and tickets: pintofscience.com.au/events/brisb... #pintofscience #Pint25 #PintAU25

Oldest reference I’ve ever seen while reviewing — 1667, Antonie van Leeuwenhoek. From the first observation of bacteria under a handcrafted microscope to modern phylogenetics. Science stands on the shoulders of giants — even from 400 years ago. #Science #Evolution #AcademicLife

Just attending a talk by Professor Warwick from QUBIC at #BrisScience on “Bringing Quantum to Life: How Quantum technologies may shape the future of society”. Exciting times ahead as quantum algorithm unravel mysteries of life. #Quantum #Science

Missense mutations impact protein function, but no single predictor is perfect. MissenseViewer integrates AlphaMissense, ESM1b, and VESPA predictions, mapping them onto protein structures to provide a richer, more interpretable view of mutation effects. #science #health #precisionmedicine #AI

Michael Healy is first speaker of the Anders early career investigators session. The scientists of the future (and the present!).

Professor Frances Separovic documents her tough journey in #Science. A trailblazing scientist who defied the odds and carved her path in a time when women in science faced unimaginable barriers. Her story is a testament to the power of determination. #WomenInScience @lorneproteins.bsky.social

Syd Leach remembered at the 50th #LorneProtein conference. @lorneproteins.bsky.social

Structome-TM: Complementing dataset assembly for structural phylogenetics by addressing size-based biases https://www.biorxiv.org/content/10.1101/2025.02.08.637224v1

Structome-TM preprint now live @ www.biorxiv.org/content/10.1... @biorxivpreprint.bsky.social #Science #Structome #StructuralPhylogenetics

#Structome began as an initiative to explore #evolutionary signals from #proteins sharing a structural neighborhood. It uses Q-score to rapidly gather datasets & build NJ trees. To highlight usage of Q-score, the tool is now called Structome-Q. App available here: biosig.lab.uq.edu.au/structome_q/

This is the green tree python (Morelia viridis), housed at the Queensland Museum, Brisbane. This photo presents an opportunity for a science class. #Python #snake #reptile #QMkurilpa #qldmuseum #nikonphotography #nikonz6ii

Setting this up for my photography. Hopefully will more time for this soon.