Nicola Dalbeth
@nicoladalbeth.bsky.social
📤 345
📥 405
📝 4
Rheumatologist, Tāmaki Makaurau
reposted by
Nicola Dalbeth
The Lancet Rheumatology
22 days ago
Our May 2026 issue is live! Including research on
#hyperuricaemia
,
#gout
, zoster
#vaccine
, and
#JIA
, plus much more!
www.thelancet.com/journals/lan...
Cover by
@emma-cheng.bsky.social
#Medsky
#Rheumsky
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reposted by
Nicola Dalbeth
Nature Reviews Rheumatology
5 months ago
A look back at the 2025 Nature Reviews Rheumatology covers, our art editor Steven Hall is brilliant🎨👏 Looking forward to the wonderful cover art that 2026 will bring!
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reposted by
Nicola Dalbeth
GUCDD MDPI
6 months ago
📢 New Publication Alert! 📝 Title: The Fast-Evolving Landscape of Treatments for Calcium Pyrophosphate Deposition Disease! 👥 Authors: Vicky Tai, Charlotte Jauffret,
@nicoladalbeth.bsky.social
and Tristan Pascart 🔗 Read the full article here:
www.mdpi.com/2813-4583/3/...
#CPPD
#gout
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https://www.mdpi.com/2813-4583/3/4/22
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reposted by
Nicola Dalbeth
ACR Journals
6 months ago
Investigating whether fractional excretion of urate (FEUA) modulates urate-lowering response to allopurinol showed that allopurinol was modestly more effective in patients with low FEUA, likely due to decreased oxypurinol renal clearance Arthritis Care & Research
doi.org/10.1002/acr....
#Medsky
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reposted by
Nicola Dalbeth
ACR Journals
6 months ago
Colchicine initiation after gout diagnosis associated with modestly (12%) lower risk of total joint arthroplasty (vs. those who did not initiate colchicine) UK population-based cohort study (IQVIA Medical Research Database) Arthritis & Rheumatology
doi.org/10.1002/art....
#Medsky
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reposted by
Nicola Dalbeth
Jamie Collins
6 months ago
Excited to share the results of the TeMPO (Treatment of Meniscal Problems in Osteoarthritis) trial, published today in NEJM:
www.nejm.org/doi/full/10....
A labor of love from the
#BWH
#oracore
team, with partners in Buffalo, Pittsburgh, and Cleveland. 879 randomized with the COVID in the middle!
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A Randomized Trial of Physical Therapy for Meniscal Tear and Knee Pain | NEJM
Physical therapy is routinely recommended for knee pain attributed to a degenerative meniscal tear, but its efficacy has not been established. We randomly assigned participants 45 to 85 years of ag...
https://www.nejm.org/doi/full/10.1056/NEJMoa2503385
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reposted by
Nicola Dalbeth
The European Alliance of Associations for Rheumatology
7 months ago
🌟Meet Dr. Francisca Sivera, the new EULAR Education Committee Chair! She assumes this role with a strong commitment to collaborating with diverse professionals to advance high-quality rheumatology training across Europe. Watch the full interview here:
https://pulse.ly/p3iftscuzf
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reposted by
Nicola Dalbeth
Rheum Cat
7 months ago
The
#GCAN2025
Gold Medal Award goes to Tony Merriman of UAB for his work, his mentorship, and his service My favorite are these talks where we hear about someone's career but also their reflections on what has mattered
#ACR25
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reposted by
Nicola Dalbeth
Rheum Cat
7 months ago
Tony Merriman gives shoutout to
@nicoladalbeth.bsky.social
"who proudly told me last week that she would sleep through my talk" 😆 I mean, it's like 2am in NZ right now
#GCAN2025
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reposted by
Nicola Dalbeth
Tuhina Neogi, MD, PhD
7 months ago
Great start to
#GCAN2025
with strong representation from STOP-Gout trial, fun great debate (with hats), proud of mentee presentations, & great to see collaborators in person with
#Burt
@rheumcat.bsky.social
@nicoladalbeth.bsky.social
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reposted by
Nicola Dalbeth
Rheum Cat
7 months ago
Outcomes
#GCAN2025
year in review Liu et al RCTs and registries for gout are not representative of the US population and tx effects may not be generalizable
#ACR25
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reposted by
Nicola Dalbeth
Rheum Cat
7 months ago
Chair Dr Bob Terkeltaub shows the growth of this meeting
@g-cangout.bsky.social
#GCAN2025
Thanks for continuing to have this meeting as hybrid, even if the meeting is right before
#ACR25
Taking a week + out for travel is often not possible
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reposted by
Nicola Dalbeth
Rheum Cat
7 months ago
idk, that felt like a really effective debate strategy from
@nicoladalbeth.bsky.social
🧢
#GCAN2025
#ACR25
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reposted by
Nicola Dalbeth
Rheum Cat
7 months ago
Dalbeth rebuttal: -data presented do not represent the average pt with gout Final vote: 61% vote no
#GCAN2025
#ACR25
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reposted by
Nicola Dalbeth
Rheum Cat
7 months ago
⭐CPPD nomenclature - Silvia Sirotti and Georgios Filippou We are deep in the Delphi rounds right now and I must confess I no longer remember what each P and each D stands for at this point 😵💫 (And I thought axSpA nomenclature discussions were wild)
#GCAN2025
#ACR25
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reposted by
Nicola Dalbeth
Thang Le, PharmD, MBA, BCPS, RPh
7 months ago
Dr. Tim Kwok emphasized that “difficult-to-treat gout” goes beyond urate levels, involving persistent inflammation, reduced function, and higher healthcare use. A holistic approach addressing clinical, patient, and system factors is key.
#2025GCAN
#Gout
#Rheumatology
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reposted by
Nicola Dalbeth
Rheum Cat
7 months ago
#GCAN2025
Great Debate: : The Standard Serum Urate Target in Gout Should Be < 5mg/dL for the Average Patient Pro: Thomas Bardin Con:
@nicoladalbeth.bsky.social
Audience pre-vote in support of the statement
#ACR25
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reposted by
Nicola Dalbeth
ACR Journals
8 months ago
Post hoc analysis of the COLCHICORT trial (colchicine vs prednisone for acute CPP crystal arthritis) identified factors predictive of arthritis resolution. Prednisone appeared to perform better in achieving pain relief after 2 days of treatment AC&R
doi.org/10.1002/acr....
#Medsky
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reposted by
Nicola Dalbeth
ACR Journals
8 months ago
Mouse model study found short-term intermittent fasting prevented crystal-induced inflammation & induced production of anti-inflammatory metabolites, such as ketone body BHB, corticosterone, & spermidine. Spermidine supplementation reproduced anti-inflammatory effects A&R
doi.org/10.1002/art....
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reposted by
Nicola Dalbeth
ACR Journals
8 months ago
International survey study of people with asymptomatic hyperuricemia looked at perceptions about hyperuricemia and urate-lowering therapy. Hyperuricemia was not well understood, and most perceived minimal consequences of asymptomatic hyperuricemia AC&R
doi.org/10.1002/acr....
#Medsky
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reposted by
Nicola Dalbeth
BU/BMC Rheumatology
9 months ago
Thanks to
@medscape.com
for highlighting our work
www.medscape.com/viewarticle/...
add a skeleton here at some point
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reposted by
Nicola Dalbeth
ACR Journals
11 months ago
Target trial emulations compared CV safety of NSAIDs vs colchicine among patients with gout starting allopurinol, and found NSAID prophylaxis was associated with higher risk of CV events than colchicine or no prophylaxis Arthritis & Rheumatology
doi.org/10.1002/art....
#Medsky
#Rheumsky
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reposted by
Nicola Dalbeth
Nature Reviews Rheumatology
11 months ago
✨July Issue✨| Factors beyond urate levels for managing gout flares In this Comment article, the authors highlight the importance of considering factors beyond urate levels to prevent gout flares and improve the quality of life of individuals with gout.
bit.ly/4liJVTL
#Rheumsky
#Medsky
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Factors beyond urate levels for managing gout flares - Nature Reviews Rheumatology
Urate crystals alone are required but not sufficient to trigger gout flares; they can also be modulated by environmental, metabolic, genetic and epigenetic factors. Avoiding large variation in urate l...
https://bit.ly/4liJVTL
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reposted by
Nicola Dalbeth
JAMA
11 months ago
Addressing patients’ expectations can enhance treatment outcomes and reduce adverse effects. This JAMA Insights offers four communication strategies to improve clinician-patient interactions.
ja.ma/3Hsek2L
#MedSky
#MedEd
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reposted by
Nicola Dalbeth
ACR Journals
12 months ago
Phase 3 RCT in Chinese patients with gout showed dotinurad 4 mg/day was superior to febuxostat 40 mg/day in achieving serum urate levels ≤6.0 mg/dL at week 24. Treatment-emergent AE incidence was similar between treatment groups Arthritis & Rheumatology
doi.org/10.1002/art....
#Medsky
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reposted by
Nicola Dalbeth
Morgan Davie
12 months ago
Feels like a good time to share this - Don McGlashan playing Anchor Me last week for RNZ, a stunning version
youtu.be/qlAJjSpi5T0?...
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Don McGlashan - Anchor Me (Live at RNZ)
YouTube video by RNZ Music
https://youtu.be/qlAJjSpi5T0?si=_1GlptIaH9jL4ySF
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reposted by
Nicola Dalbeth
ACR Journals
12 months ago
Arthritis Care & Research June Editor's Pick 👉 Gout Flares After Stopping Anti-Inflammatory Prophylaxis: A Rapid Literature Review and Meta-Analysis
doi.org/10.1002/acr....
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reposted by
Nicola Dalbeth
Nature Reviews Rheumatology
12 months ago
✨June Issue✨| Current challenges in understanding the epidemiology of calcium pyrophosphate crystal deposition Jauffret & Pascart highlight some of the hurdles in advancing the understanding of the epidemiology of calcium pyrophosphate crystal deposition
bit.ly/4kDBPnB
#Rheumsky
#Medsky
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Current challenges in understanding the epidemiology of calcium pyrophosphate crystal deposition - Nature Reviews Rheumatology
Calcium pyrophosphate deposition (CPPD) disease is secondary to the pathological accumulation of calcium pyrophosphate (CPP) crystals inside joints and involves acute or chronic inflammatory arthritis...
https://bit.ly/4kDBPnB
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reposted by
Nicola Dalbeth
ACR Journals
12 months ago
Serum urate has been used as a surrogate marker for gout flares in gout clinical trial design. Commentary in A&R discusses the importance of gout flare and calls for greater focus on gout flare as a clinical trial outcome
doi.org/10.1002/art....
#Medsky
#Rheumsky
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The importance of considering the gout flare: let's learn to walk and chew gum at the same time in gout clinical trial design
Click on the article title to read more.
https://doi.org/10.1002/art.43233
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reposted by
Nicola Dalbeth
ACR Journals
about 1 year ago
New installment in the A&R immunology series describes 3 broad stages of acute inflammation in gout: initiation, leukocyte mobilization, & self-resolution, and examines the role of the NLRP3 inflammasome in acute MSU crystal-induced inflammation
doi.org/10.1002/art....
#medsky
#rheumsky
#immunosky
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reposted by
Nicola Dalbeth
Nature Reviews Rheumatology
about 1 year ago
ICYMI: New content online:
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Factors beyond urate levels for managing gout flares
Nature Reviews Rheumatology, Published online: 23 April 2025; doi:10.1038/s41584-025-01255-4Urate crystals alone are required but not sufficient to trigger gout flares; they can also be modulated by environmental, metabolic, genetic and epigenetic factors. Avoiding large variation in urate levels, maintaining prophylaxis until crystal clearance and initiating low-dose urate-lowering therapy are efficient strategies for disease management.
https://bit.ly/3YQHiyY
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reposted by
Nicola Dalbeth
Nature Reviews Rheumatology
about 1 year ago
✨April Issue✨| Hyperuricaemia and gout in the Pacific In this article, the authors provide an overview of gout and hyperuricaemia in Indigenous peoples of the Pacific region
#Rheumsky
#Medsky
Free to read here:
bit.ly/41LQgj2
🔓
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Hyperuricaemia and gout in the Pacific
Nature Reviews Rheumatology - In this Review, the authors provide an overview of gout and hyperuricaemia in Indigenous peoples of the Pacific region, including discussion of genetic, clinical and...
https://bit.ly/41LQgj2
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reposted by
Nicola Dalbeth
Nature Reviews Rheumatology
about 1 year ago
✨Our April Issue is out now!✨ Featuring articles on: - Hyperuricemia and gout in the Pacific🌏 - Targeting synovial joint stem and progenitor cells🎯 - The role of the immune system in OA 🧫 - Delineating inflammatory from non-inflammatory PsA🦴
#Rheumsky
#Medsky
bit.ly/3FSVhxC
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reposted by
Nicola Dalbeth
Nature Reviews Rheumatology
over 1 year ago
📣Did you know that we now publish Evidence-Based Guidelines?📣 You can view all of the EBGs that have been published in NRR using the link below (free to access!) 🔓
bit.ly/3CA9r5B
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reposted by
Nicola Dalbeth
Dr. John Cush
over 1 year ago
2024 In Memorium In 2024, Rheumatology lost many esteemed clinicians who cared for countless MSK patients and propelled scientific advancements impacting millions.
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2024 In Memorium | RheumNow
Sadly, in 2024, Rheumatology lost many of our greatest brethren, mentors, do-gooders and clinicians. These clinicians were responsible for the care of hundreds of thousands with MSK problems, while…
https://buff.ly/4fWRY4X
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reposted by
Nicola Dalbeth
ACR Journals
over 1 year ago
ADVANCE open-label trial in uncontrolled gout found response rate with pegloticase (Peg) + MTX following failed Peg monotherapy was 9%, much lower than in Peg-naive pts Results show challenge of overcoming established anti-Peg antibodies in pts with previous loss of urate-lowering response
#Medsky
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reposted by
Nicola Dalbeth
ACR Journals
over 1 year ago
Potential urate-lowering approaches that employ or modulate gut microbiota and their molecules
#Medsky
#Gastrosky
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reposted by
Nicola Dalbeth
The Journal of Rheumatology
over 1 year ago
Research Article The Significance of Intracellular Versus Extracellular Calcium Pyrophosphate Crystals in Diagnosing Calcium Pyrophosphate Crystal Arthritis 📖
www.jrheum.org/cgi/content/...
#calciumpyrophosphatedehydrate
#pseudogout
#synovialfluid
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reposted by
Nicola Dalbeth
Tuhina Neogi, MD, PhD
over 1 year ago
Finally put my copy of 12th edition of Firestein&Kelley’s Textbook of
#Rheumatology
on my bookshelf beside the 6th edition from when I was a resident. Would never have imagined seeing my name on the cover! Add yours to your shelf! Discount code BAFF20
#FiresteinKelleyRheum12
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reposted by
Nicola Dalbeth
ACR Journals
over 1 year ago
January 2025 Arthritis & Rheumatology Editor's Pick Novel Genetic Loci in Early-Onset Gout Derived From Whole-Genome Sequencing of an Adolescent Gout Cohort
doi.org/10.1002/art....
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reposted by
Nicola Dalbeth
Ada Lovelace Day
over 1 year ago
Tsai-Fan Yu was a renowned Chinese-American medical doctor whose pioneering research helped make gout a curable disease, linked gout to hypertension and diabetes, and established one of the first systematised lab tests for diagnosing rheumatoid arthritis.
https://adalovelaceday.substack.com/p/pro..
.
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reposted by
Nicola Dalbeth
ACR Journals
over 1 year ago
Meta-analysis examined gout flare following stoppage of anti-inflammatory prophylaxis. Results showed gout flares are common after prophylaxis, but with time return to levels seen while on prophylaxis In AC&R
doi.org/10.1002/acr....
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reposted by
Nicola Dalbeth
Saori Abe
over 1 year ago
ard.bmj.com/content/earl...
📣🆕 2024 EULAR points to consider on the initiation of targeted therapies in patients with inflammatory arthritis and a history of cancer
#Rheumsky
#Medsky
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2024 EULAR points to consider on the initiation of targeted therapies in patients with inflammatory arthritis and a history of cancer
Background Potential associations between targeted therapies and a new cancer in patients with inflammatory arthritis (IA) and a previous malignancy are a frequent concern in daily rheumatology practi...
https://ard.bmj.com/content/early/2024/12/20/ard-2024-225982
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reposted by
Nicola Dalbeth
TheDaoIndex
over 1 year ago
Can we finally leave the Krill to the Whales? Krill is not beneficial for knee OA!
#ACR24
@rheumnow.bsky.social
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reposted by
Nicola Dalbeth
TheDaoIndex
over 1 year ago
Finally got a chance to watch
#ACR24
Year in Review: Cipoletta et al. eval pts after 1st diagnosis gout/flare: these patients had 1.7X increased CV risk 30-120 days post-flare, stressing need for CV risk assessment and management from time of first flare @rheumnow
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reposted by
Nicola Dalbeth
ACR Journals
over 1 year ago
How is imaging tech shaping the future of gout care? Drs. Nicola Dalbeth & Dansoa Tabi-Amponsah share insights on DECT imaging & its role in achieving gout remission Listen at:
sites.libsyn.com/436041/dect-...
Their study in AC&R:
acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
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reposted by
Nicola Dalbeth
Kazuki Yoshida
over 1 year ago
Immunology for the Rheumatologist: Arthritis & Rheumatology Introduces a New Problem-Based Immunology Review Series With Great Educational Potential - PubMed
https://buff.ly/4hZt0nN
I learned A&R started this immunology series.
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reposted by
Nicola Dalbeth
Saori Abe
over 1 year ago
Woke up and realized that
@rheumnow.bsky.social
is here now🙌 I was checking through their article and YouTube to catch up
#ACR24
📺☺️
#Rheumsky
❤️
add a skeleton here at some point
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reposted by
Nicola Dalbeth
Rheum Cat
over 1 year ago
And I found this old tweet from @philipcrobinson from the first @ACRheum I attended in 2016, and it reminds me of why we do what we do, and what this program is about
@jyazdanymd.bsky.social
@profbeckyg.bsky.social
@nicoladalbeth.bsky.social
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reposted by
Nicola Dalbeth
over 1 year ago
We are delighted to announce that the Best PhD Thesis award is open! We are inviting young scholars to send us their applications! You have to have defended in 2024. The process is open from November to May! 📷 For more information:
mdpi.com/journal/gucd...
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Gout, Urate, and Crystal Deposition Disease
Gout, Urate, and Crystal Deposition Disease, an international, peer-reviewed Open Access journal.
https://mdpi.com/journal/gucdd/awards/3057…
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