On the April cover of #ScienceImmunology: The brain’s perception of hunger (rather than nutrient availability) regulates circulating immune cell dynamics. Read more here: www.science.org/doi/10.1126/...

Science Swifties this is a must-read 🤩

In #Science #Immunology this week: human naïve B cells can bind and neutralize #H5N1, potentially offering protection against #birdflu.

I’ll be here (joint with T cell Differentiation in Tissue Microenvironments) next week! Send me a message or email if you’d like to set up a time to chat. Looking forward to an exciting meeting!

New review out in #science #immunology on tuberculosis immunopathology by @tomscriba.bsky.social et al.🫁🦠 www.science.org/doi/10.1126/...

This week in #ScienceImmunology: Germinal Center B cells require asparagine (Asn) #metabolism for their function. GC B cells can acquire exogenous Asn from their local environment, but when Asn is limited, they utilise the enzyme asparginine synthetase. @ajclarke.bsky.social @yfy1.bsky.social

Thrilled to share our latest work on how the non-essential amino acid #asparagine metabolically regulates germinal centers. Huge thanks to my PhD supervisor @ajclarke.bsky.social, colleagues, and collaborators at the @ndorms.bsky.social @ox.ac.uk and @crick.ac.uk www.science.org/doi/10.1126/...

Best #Nikolaus 🎅! Our paper on how the 🫁 microenvironment can shape #innate immunity against #viruses is out @sciimmunology.bsky.social This was a herculean effort brilliantly led by @pauljbaker.bsky.social who singlehandedly established the model in the lab during the pandemic. 🧪 #Immunosky 1/9

🙏 to @niaidnews.bsky.social, first author @pauljbaker.bsky.social and my amazing lab team, our collaborators @kerryhilligan.bsky.social @danbarberphd.bsky.social 🙏to editor extraordinaire @hannah-isles.bsky.social and the reviewers who guided us along the way 9/9 www.science.org/doi/10.1126/...

Two new studies in Science describe synthetic biology-based strategies that expand the possibilities of harnessing immune cells to treat disease. Learn more in this week's issue: scim.ag/49nfztS

Now in #Science #Immunology: Ziang Zhu, Tuoqi Wu, Chen Yao et al at UT Southwestern show that #NRF2 suppression mediated by the #redox sensor #KEAP1 is required for optimal expansion of #CD8 #TCells during chronic antigen exposure!

New in #ScienceImmunology: Research from @boztugk.bsky.social and team identifies an inborn error of #immunity caused by human LTβR deficiency, resulting in defective stromal cell signaling and impaired humoral immune responses. Read more: www.science.org/doi/10.1126/...

Last week in #ScienceImmunology: An alternative approach to target TIM-3 for cancer #immunotherapy? Zhang et al. found that palmitoylation of human TIM-3 promoted its stability. Blocking palmitoylation accelerated TIM-3 degradation, prevented immune #exhaustion and promoted anti-tumor #immunity

Fantastic visit to @cambridgeuni.bsky.social pathology department today. Lots of exciting science and beautiful place to visit 🧪 thanks to @labliston.bsky.social for hosting!

At #ScienceImmunology, I lead a fantastic team of #research #editors comprising Chris Fogg (@cnfogg.bsky.social), Claire Olingy (@claireolingy.bsky.social), and Hannah Isles (@hannah-isles.bsky.social)! Be sure to give them a follow! www.science.org/journal/scii...

New here 🙋🏻‍♀️

let's do this!! I am excited to reconnect with scientists here. thx @oneyrolles.bsky.social for the push 😀 #Immunology announcement: SAVE THE DATE: 26-29 August in Basel 🇨🇭 Mauro Gaya (CIML) and I are organizing an #EMBO workshop on Adaptive #immunity in barrier tissues; details coming soon!