Thrilled to share our new paper comparing different LLMs to extract TNFi reasons and treatment trajectories from UCSF de-identified EHR data with @bmeow19.bsky.social, A. Garcia-Agundez and @jyazdanymd.bsky.social published in JAMIA open. academic.oup.com/jamiaopen/ar... @ucsf-bchsi.bsky.social

A paper in Nature describes an AI system that can prove complex mathematical theories. The system, Google DeepMind’s AlphaProof, has achieved a silver medal-worthy performance at the 2024 International Mathematics Olympiad. go.nature.com/4qUObvN 🧪

The T cells in these patients showed increased metabolic activity. Elevated levels of inflammatory molecules (IL-6, IL-12, and type I interferon) may be driving the aggressive T cell behavior. #ACR25

Atul Butte, MD, PhD, helped define the field of translational bioinformatics and inspired countless colleagues and trainees. He will be remembered for his brilliant mind, infectious optimism, generous mentorship.

Fresh from the oven 🧨💥 We show that CD4 T cells, especially Tregs, control host-microbiota symbiosis and intestinal barrier integrity to prevent inflammaging, tissue senescence and aging-related multimorbidity 🔥 👵🏻 www.science.org/doi/10.1126/...

Congrats to @mariamarcosalvador.bsky.social on her first publication, just out in @oacjournal.bsky.social ! A systematic literature review on TCR and HLA in osteoarthritis: 🔗 www.oarsijournal.com/article/S106... @enkrnita.bsky.social @jeremiesellam.bsky.social @sorbonne-universite.fr

The UCSF community mourns the passing of Atul Butte, MD, PhD, a bold thinker, inspiring mentor and founding director of the Bakar Computational Health Sciences Institute. tiny.ucsf.edu/tGz3QY

Review @natrevrheum.nature.com @deepakarao.bsky.social Immune-cell profiling to guide stratification and treatment of patients with rheumatic diseases www.nature.com/articles/s41...

Recently in #Science #Immunology: Van der Veeken & al @ IMP @viennabiocenter.bsky.social generated 🐁 w auxin-inducible degradable #Foxp3! Tissue #Tregs minimally unaffected @ homeostasis but highly dependent on continuous Foxp3 activity in models of #autoimmunity, #viral #infection, & #cancer !

🚨 NEW 🚨 🤩 This month's Editors Choice (Clinical) is about intestinal health and hand #osteoarthritis Read more from @mbinvignat.bsky.social @jeremiesellam.bsky.social - www.oarsijournal.com/article/S106...

Check out our new editorial on molecular endotypes and theratypes in osteoarthritis with @jeremiesellam.bsky.social, just out in Annals of the Rheumatic Diseases ard.eular.org/article/S000... @crsa-paris.bsky.social @sorbonne-universite.fr

We’re proud to celebrate @atulbutte.bsky.social on his election to the American Academy of Arts and Sciences, one of the nation’s oldest honor societies. A leader in biomedical data science, his work is reshaping how we diagnose and treat disease. tiny.ucsf.edu/CUz7gN

Happy to share our new article on Intestinal Permeability serum biomarkers in Erosive hand OA with @jeremiesellam.bsky.social @larhumato.bsky.social @enkrnita.bsky.social and team Read the paper here: www.oarsijournal.com/article/S106... @crsa-paris.bsky.social @oacjournal.bsky.social