Paul Nurse describing the main job of a PI (From ‘The Thinking Game’, 2024)

I wanted my first @bsky.app post to be witty, thoughtful & somewhat self-depreciating. I wanted to make sure I could highlight all the exciting computational cancer evolution research my lab does, without sounding too arrogant. But, instead I posted this. (At least it's within the character limit.)

An excellent systematic analysis of RBPs by @quaidmorris.bsky.social and colleagues (with a tiny contribution from us) #RNAsky #RNAbiology

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Very excited to share our new paper on the influence of biological sex and smoking in the clonal landscape of normal human bladder, just published in Nature. A big thank you and congrats to all the authors, specially to @raquelbmi.bsky.social for all the shared efforts in this journey! ⬇️More info⬇️

Clone copy number diversity is linked to survival in lung cancer @nature.com @zaccasimo.bsky.social @nickymcgranahan.bsky.social www.nature.com/articles/s41...