Congrats to first author, Dr. Andrea Alber, co-senior-author Dr. Kostas Alysandratos, and all the team @crem-boston.bsky.social . For patients with pulmonary fibrosis this new human model system should help propel drug discovery and therapeutic development. #helpisontheway! #itsthecells!

The Kotton Lab is pleased to announce our latest work, just posted at biorxiv: Bidirectional fibrogenic cross-talk revealed in a human iPSC-derived epithelial-mesenchymal co-culture model of pulmonary fibrosis www.biorxiv.org/content/10.6...

Just out @ajrcmb.bsky.social, our review of how axolotl salamander lung regeneration offers many hints for advancing human lung regeneration research for our patients: atsjournals.org/doi/abs/10.1...

Yesterday, October 7, Sir John Gurdon passed away. Dr. Gurdon was awarded the Nobel Prize in Physiology or Medicine in 2012, together with Shinya Yamanaka. Through a series of experiments using Xenopus eggs, Gurdon showed that the nucleus of a mature cell can be reprogrammed to a pluripotent state.

Delighted to give a talk at the Vermont Lung Stem Cell Conference last week. Also got to visit with @kottond.bsky.social, Finn Hawkins, Joe Kaserman, and Kostas Alysandratos - all legends of the lung regeneration field at the CReM Boston University @crem-boston.bsky.social #CureIPF

Thrilled to host Dr. Hao Zhu @crem-boston.bsky.social as this year's 10th anniversary Annual Anita Kurmann Memorial Lecturer! Inspiring science from the @Zhu_Lab in Anita's honor. #itsthecells

Excited to help spread the word about the latest advances in stem cell research! #itsthecells!

Great research by our own, Dr. Elizabeth Taglauer @The_BMC @CReM_Boston, featured today: "One NICU Doctor Is Finding the Cellular Clues to Preeclampsia’s Impact on Babies" healthcity.bmc.org/one-nicu-doc... #itsthecells #helpisontheway!

Announcing our latest publication, just out today @NatureComms, advancing our understanding of interstitial lung disease. Congrats to co-senior authors Drs. Jeremy Katzen and Kostas Alysandratos and their teams @Penn @CReM_Boston. Check it out here: www.nature.com/articles/s41...

“David Baltimore, a biologist who in 1975 won a Nobel Prize for a startling discovery that seemed to rock the foundations of the fledgling field of molecular biology, died on Saturday at his home in Woods Hole, Mass. He was 87.”🧪🩺

An incredible advance in regenerative medicine, published this week: Stem Cell–Derived, Fully Differentiated Islets for Type 1 Diabetes | NEJM: www.nejm.org/doi/full/10....

Another impressive clinical accomplishment thanks to regenerative medicine research, just out @NEJM: #itsthecells! #helpisontheway! Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression | www.nejm.org/doi/full/10....

So great to be together with so many @CReM_Boston alumni and current members at the #2025LungGRC!

The #RespirERA IHU was out in force at the #2025LungGRC in Lucca with Manon Durandy, Laetitia Seguin (IRCAN) and @laure-em.bsky.social #IPMC Great science, wonderful exchanges with old colleagues and new connections and what a gorgeous place ! #LungResearch

Farewell #2025LungGRC! Great memories as we say farewell, handing off the ball to our new Chairs. #2025LungGRC. @GordonConf

The traditional epithelium vs mesenchyme soccer game, won this year by a new team, Bronchospurs at the 2025 Lung Gordon Research Conference! #2025LungGRC. @GordonConf

Today we officially hand over our meeting Chair roles to the next Chairs: Drs. Cardoso and Crotty Alexander on Day 5 of the 2025 Lung Gordon Research Conference. Special thanks to Dr. Sue Majka, current Chair!

And we are live at the #grclung2025 in Tuscany!

Our latest work, just out now at JCI Insight on iPSC modeling of pulmonary fibrosis. The latest chapter in the Kotton-Beers collaboration! Congrats to co-first authors Drs. Rodriguez and Alysandratos for leading the way! insight.jci.org/articles/vie...

Congrats @MingxiaGu and all the teams collaborating on this latest advance in stem cell and lung organoid research, just out @CellCellPress! and thanks for including our iPSCs! www.cell.com/cell/fulltex...

Truly amazing pluripotent stem cell clinical trial results for diabetes! “Off-the-shelf stem cell therapy for type 1 diabetes yields more positive results”. Also published in ⁦‪@NEJM‬⁩ this week. #helpisontheway! www.statnews.com/2025/06/20/s...

RFK Jr. plans to bar NIH scientists from top journals like NEJM & JAMA, replacing them with government-run outlets. This would delegitimize taxpayer-funded research, warns Dr. Adam Gaffney of Harvard Medical School. www.washingtonpost.com/health/2025/...

“This is incredibly disappointing,” said Dr. Camille Kotton, an infectious diseases physician who cares for immunocompromised patients, and a former adviser to the CDC ”I don’t know why they would make this restriction; I don’t know of any indication to make this change,”

An amazing clinical triumph for regenerative medicine! A great example of how federal funding results in patient cures. Let’s keep these stories going, America! “World's First Patient Treated with Personalized CRISPR Therapy” #helpisontheway! www.pennmedicine.org/news/news-re...

The ATS is pleased to recognize Lauren Kearney, MD, as the 2025 Ziskind Clinical Research Scholar Award winner. Dr. Kearney aims to advance early detection of lung cancer, increase access to preventive care and treatment, and reduce health disparities. Read more: www.thoracic.org/professional...

"There is perhaps no better demonstration of the folly of human conceits than this distant image of our tiny world. To me, it underscores our responsibility to deal more kindly with one another, and to preserve and cherish the pale blue dot, the only home we've ever known." - Carl Sagan

We are so proud of our director, @kottond.bsky.social, for being awarded BU’s Innovator of the Year!

So grateful to all our team- current and past graduates of our lab — and to all the 10 faculty leaders who each lead teams of innovators at the CReM #itsthecells!

America don't let up now. Preserve the NIH funding that lets us train the next generation of scientists and researchers! Carl Sagan would have said the same! bsky.app/profile/saga...

Carl Sagan's prescient words remain so important today. America, don't let up now: NIH funding lets us train the next generation of scientists and researchers!

I agree with Senator Collins: "GOP Senator Collins says Trump’s layoffs of scientists, cuts to biomedical research ‘must be reversed’ ..." www.statnews.com/2025/04/30/n... via @statnews.com

From bench to bedside: incredible progress in heart regenerative medicine research! #helpisontheway! #itsthecells!

What a fantastic Mass Thoracic Society meeting this year. Thank you to MTS President Dr. Finn Hawkins @BUPulmonary for leading an outstanding day of lung 🫁 clinical and research presentations!

Congrats to our poster award winners, Kevin and Braden, for their excellent work at the BU CTSI symposium!

The Annual MTS meeting will take place on April 10th 2025 and features BU Pulmonary presentations, from Drs. DJ Wallman, Jonathan Chang, Liz Klings, Darrell Kotton, and Burton Shen. See below for the agenda and registration details. We hope to see you there!

Today, we were treated to a great talk from Dr. Pulin Li of @whiteheadinstitute.bsky.social !

Vote for the CReM's own Valerie Gouon-Evans, in #STATMadness! Her work using iPSCs to regenerate liver in vivo, earned her a spot in the sweet 16. Let's get her to the Elite 8: www.statnews.com/feature/stat...

Gene editing is here for Alpha-1! @BeamTx clinical trial results announced: "the world’s first results in patients who have had a disease-causing mutation corrected at the genetic level." @AlphaFriend #helpisontheway #becausescience! Press release: investors.beamtx.com/news-release...

We've known about the gut-brain axis. Now we're learning about the gut-brain-lung axis whereby food intake can trigger an immune response in the airway. www.cell.com/neuron/fullt...

Science is for everyone!

Inspiring day for scientists in Washington DC #standupforscience2025 Thank you @standupforscience.bsky.social

“The slashing of foreign aid deprives the world of American leadership and expertise, but it also locks the US out of global discussions, Dr. Fukuda said: ‘For the life of me, I cannot see the justification or the reason for this very calculated, systematic approach to pull down public health.’”🧪🩺🦠

Tom Maniatis coming in hot in @CellCellPress to spell out in no uncertain terms what cutting indirect cost rates to 15% will cost science. And a call to action: "A united front...is essential to preventing this devastating policy from taking effect." 💯 www.cell.com/cell/fulltex...

Why tax dollars are well spent on research: the return on investment is extraordinary! Explained in detail here: Safeguarding the future of biomedical science in the United States: Cell www.cell.com/cell/fulltex...

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...

No matter who you voted for the NIH is bipartisan and is here for you. Don’t stop now, America! So many medicines and treatments on the market today began with NIH funding. And we’re just getting warmed up! Keep it going! Image below from: Bruce Levine, Ph.D. @BLLPHD

A really thoughtful piece about one of the great advances in human health that humankind has engineered: vaccinations for our children... just out from a renowned pediatrician | @NEJM #mustread! www.nejm.org/doi/full/10....

A huge welcome to our newest recruit! The @MichaelHerriges Lab is launching @CReM_Boston, and we can’t wait to see all the #lungregeneration discoveries that will follow. Congratulations!! #helpisontheway! @CReM_Boston @BUPulmonary

I know what you mean :)