Jan Haaker
@janhaaker.bsky.social
📤 503
📥 501
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Social learning Neuropharmacology
@Isnlab.bsky.social
Alumnus
@jungeakademie.bsky.social
pinned post!
Can we learn about unpredictable threats via observation of others? Yes, temporally predictable and unpredictable threats are learned by distinct contributions of the amygdala and hippocampus. ALSO: We find higher activation in the amygdala and anterior insula to others' pain that serves learning.
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Resolving temporal threat uncertainty by observational learning involves the amygdala, hippocampus and anterior insula
While the neurobiological distinction between temporally predictable (cued) and unpredictable (contextual) threats has been well-characterized in direct learning using the NPU paradigm, it is poorly u...
https://www.biorxiv.org/content/10.1101/2025.10.21.682164v1
9 months ago
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Johannes Felsenberg
1 day ago
If you’re at the FENS Forum, consider to join our symposium: S28 – Flexible Memory Systems: Adaptive and Maladaptive Pathways! Today Hall D at 15:40! Kate Wassum, Mihaela Iordanova, Scott Waddell, and Jan Haaker. @fensorg.bsky.social
#FENS2026
fens2026.abstractserver.com/program/#/de...
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Program
https://fens2026.abstractserver.com/program/#/details/sessions/59
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Leaving for
#FENS2026
Looking forward to our symposium on Wednesday 15:40 Hall D With
@katewassum.bsky.social
@iordanova.bsky.social
@scottishwaddell.bsky.social
I will talk about Neuropharmacological adaption of threat- and safety-memories in humans
fens2026.abstractserver.com/program/#/de...
1 day ago
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Jan Haaker
3 days ago
Photographer Chantal Pinzi's photogragraphic series of women skateboarders around the world
#WomensArt
#Monday
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Jan Haaker
Ketika Garg
9 days ago
🚨This preprint is now out in PNAS:
www.pnas.org/doi/full/10....
We combine a dyadic foraging paradigm w/ computational modeling + ABM to study how people navigate differing preferences, share responsibility for shared outcomes & what that means for the group! more in 🧵⬇️
@fearbrain.bsky.social
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Jan Haaker
Dr. Andreas Strube
14 days ago
Vom Sonderforschungsbereich Treatment Expectation
@sfb-trr-289.bsky.social
wurde ich dazu interviewt, warum unser Gehirn wie eine Vorhersagemaschine ist - und wie Erwartungen unsere Wahrnehmung und unser Schmerzempfinden verändern können. Und was das für Jugendpsychiatrie bedeutet. Hier der Link:👇
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The Power of Expectations
16 days ago
In case you missed it, we have a bilingual video series called 🥜 "In a nutshell" 🥜 In this series, our scientists explain what their work has to do with expectations, what new research found, & what patients can do to feel better. Here they are all in a thread for you to browse & watch! ⤵️
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Jason Bateman: In A Nutshell
ALT: Jason Bateman: In A Nutshell
https://static.klipy.com/ii/39f2394ae36df6e199be9eb7c9fa1012/b7/c0/MnMVciQl.gif?hh=225&ww=498&mp4=QMw3PLJ7FjCg&webm=Zjz4tJH6S1SkkIfTeR5
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Jan Haaker
Dr. Andreas Strube
about 1 month ago
Many thanks to the
@biodgps-dgpa.bsky.social
and all colleagues for awarding me the DGPA Early Career Award 2026 at the fantastic
#PuG2026
! I am also grateful to the
@sfb-trr-289.bsky.social
for the support of my scientific work and the great research environment and network.
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Jan Haaker
Muhammad Hashim Satti
9 months ago
Excited to announce that this is now out in eLife as a reviewed preprint 🚀
doi.org/10.7554/eLif...
Huge thanks to the eLife editors, reviewers and our fantastic collaborators: Katharina Wille,
@nicoschuck.bsky.social
, Matt Nassar, Radoslaw Cichy, Peter Dayan and
@rasmusbruckner.bsky.social
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Jan Haaker
Rasmus Bruckner
about 1 month ago
Looking very much forward to
#PUG2026
in beautiful Heidelberg! Interested in the features and bugs of computational psychiatry 💻🧠? Join our symposium: 🕞Thursday 15:30 - 17:00 in HS 13. W\ Isabel Berwian
@lilweb.bsky.social
@hashimsat.bsky.social
@ondrejzika.bsky.social
@biodgps-dgpa.bsky.social
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The Power of Expectations
8 months ago
🗣️ Calling all healthcare professionals! The
#scicomm
team is evaluating the CRC's newsletter. For this we need input from people working with and around patients that are not part of our CRC. Fill out the 10-15min (German) survey:
sfb289.survey-uni-due.de/index.php/89...
Thanks for your support ❤️
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That’s cool!
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about 1 month ago
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This is cool
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about 1 month ago
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Jan Haaker
Ole Goltermann
about 2 months ago
A recent paper by Epp et al. in NN claimed that ~40% of reported BOLD findings could be misinterpreted. In our reanalysis, we identified several statistical issues that, in our view, undermine these conclusions.
www.biorxiv.org/content/10.6...
👇 1/11
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https://www.biorxiv.org/content/10.64898/2026.04.21.719913v1.full
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Jan Haaker
Tim Behrens
2 months ago
This is the May cover of NN but it has already been debunked on biorxiv
www.biorxiv.org/content/10.6...
Such a clear statement about the ridiculous pace of publishing (not just NN).
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Jan Haaker
Sydney Placebo Lab
about 2 months ago
An exciting opportunity to work closely with our lab - a fully funded PhD scholarship is available at the University of Sydney on the psychological mechanisms underlying the nocebo effect. Open to domestic + international applicants: - $42,754 p.a. for up to 3.5 years - Applications close 9 June
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Jan Haaker
Tamas Spisak
about 2 months ago
Many of you asked how we create those pretty whole-brain plots with the cortical outline. We just made it available as a Python package:
pni-lab.github.io/quickbrain/
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Jan Haaker
The Power of Expectations
about 2 months ago
Thanks to
@dfg.de
for interviewing our speaker
@ulrikebingel.bsky.social
about this very important topic: How expectations can make treatments work better (or worse)! Video in German:
youtu.be/5l1SLadf1ec?...
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Wie Erwartungen Medikamente wirksamer machen können - exkurs-Gespräch mit Prof. Bingel
YouTube video by DFG bewegt
https://youtu.be/5l1SLadf1ec?si=8AM9NgOVI5jRYaoo
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Jan Haaker
The old internet
4 months ago
1998 just felt right
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Jan Haaker
The Power of Expectations
about 2 months ago
It's time for another "In a nutshell" video, in which
@janhaaker.bsky.social
explains what expectations and symptoms of other people have in common! 👀 German:
youtu.be/5XFFT7dyp8M
English:
youtu.be/hcB3VnXnha0
We'd be grateful if you comment or leave a like, and subscribe for more content! 🤩
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In a nutshell with Jan Haaker - What do expectations have to do with other people's symptoms?
YouTube video by Die Macht der Erwartungen
https://youtu.be/hcB3VnXnha0
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Jan Haaker
Ulrike Bingel
about 2 months ago
Translation rocks! Congrats to
@stefaniebrassen.bsky.social
and team from
@sfb-trr-289.bsky.social
for her recent work on expectation responsiveness and longterm treatment trajectories in major depression published in Translational Psychiatry.
www.clearskyscience.com/en/10.1038/s...
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Acute placebo responsiveness predicts longitudinal expectation effects in antidepressant treatment · Clear Sky Science
Study shows that positive treatment expectations can bias emotional perception toward happiness and predict antidepressant outcomes.
https://www.clearskyscience.com/en/10.1038/s41398-026-04070-x/
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Jan Haaker
Dr. Helena Hartmann (she/her)
about 2 months ago
Seit letzter Woche ist unser Museumsexponat "Die Kraft der Erwartung" auf der MS Wissenschaft ausgestellt. Nun tourt es in den nächsten Monaten durch Polen, Deutschland und Österreich 🛳️
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excellent talk by
@hugospiers.bsky.social
about investigating navigating abilities with really creative and real-world designs.
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2 months ago
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This is why you have coffee with colleagues and just chat without agenda.
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2 months ago
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Jan Haaker
Nico Schuck
2 months ago
this is welcome news! funding decision are too noisy to make them so consequential, especially in a system already under so much strain. i hope there’ll be a different way to adapt to the increase in applications.
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bioRxiv Neuroscience
2 months ago
Opposing BOLD signals and oxygen metabolism largely arise from statistical uncertainty in metabolic estimates
https://www.biorxiv.org/content/10.64898/2026.04.21.719913v1
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Jan Haaker
Siri Leknes
3 months ago
Expectations vs outcomes for opioid analgesia, euphoria and withdrawal effects - the evidence I presented is surprising to most! Bonus content: videos of cute animal behaviours from opioid studies in pigs, butterfly fish & cats 👌✨
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Jan Haaker
The Power of Expectations
3 months ago
⭐ And here is this month's webinar! ⭐ Huge thanks again to
@sirileknes.bsky.social
from
@uio.no
for this amazing talk about opioids 💊 Watch the full talk:
youtu.be/rRQb2NhDs60
Subscribe to our channel for more cool content surrounding treatment expectations:
www.youtube.com/@SFB-TRR_289
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Webinar: Siri Leknes - When and how opioids fail to meet expectations
YouTube video by Die Macht der Erwartungen
https://youtu.be/rRQb2NhDs60
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Really important to compare empathetic responses to video vs. live interaction when observing pain in others. Nice work
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3 months ago
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Jan Haaker
Gamer Lab Wuerzburg
3 months ago
Are you a DGPA member (or thinking of becoming one 😁) conducting outstanding research in biopsychology, psychophysiology, or neuroscience? Apply now for the 2026 Early Career Award!
@biodgps-dgpa.bsky.social
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Jan Haaker
The Power of Expectations
3 months ago
Today we share the next "In a nutshell" video, in which Christine Knaevelsrud explains what expectations and recovery after surgery have in common! 🏥👩⚕️ German:
youtu.be/F8EkcnkZIi0
English:
youtu.be/yaFmCfirSNE
We'd be grateful if you comment or leave a like, and subscribe for more content! 🤩
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Kurz erklärt mit Christine Knaevelsrud - Was haben Erwartungen mit der Verwendung von Apps zu tun?
YouTube video by Die Macht der Erwartungen
https://youtu.be/F8EkcnkZIi0
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This is cool
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3 months ago
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Jan Haaker
Dr. Helena Hartmann (she/her)
3 months ago
Brauchen wir noch einen Podcast?! 🤔 In diesem Fall ist die Antwort klar JA, denn Kommunikation wird im Gesundheitswesen noch viel zu wenig berücksichtigt. Wir vom
#WissKomm
Team des
@sfb-trr-289.bsky.social
haben uns diesem Problem angenommen. Hört mal rein:
open.spotify.com/show/4L7oLh3...
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Labmeeting! And I am the grateful freerider
3 months ago
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Jan Haaker
Ulrike Bingel
3 months ago
Yeah - unser SFB Podcast „Wirkstoff Wort - der Podcast für Gute Kommunikation in der Medizin ist draußen! Hört mal rein. Danke an das großartige Public Outreach Team des SFBs!
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Jan Haaker
Dr. Andreas Strube
3 months ago
1/6 Our paper is out today in Nature Communications! From the SFB/TRR 289 Treatment Expectation
@sfb-trr-289.bsky.social
we show that temporal expectations shape somatosensory perception - for both painful heat AND non-painful cold stimuli.
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Jan Haaker
The Power of Expectations
3 months ago
Da stimmen wir natürlich zu! 🌟 Ein spannender Artikel mit u.a.
@ulrikebingel.bsky.social
👩⚕️
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Jan Haaker
Lauren Atlas
3 months ago
I am so looking forward to
#SANS2026
this week! I haven’t been since 2019 & miss my SANS family so much 🥰 Also if you or someone you know is looking for a funded postdoc or postbac, we‘re hiring! FMRI of pain & emotion in the context of a novel drug. Reach out to discuss during the meeting!
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Jan Haaker
David Amodio
3 months ago
New preprint! w/Tessa Charlesworth &
@williambrady.bsky.social
: The Psychology of Algorithmic Bias We introduce a psychology-centered framework to specify mechanisms through which human behavior interacts dynamically with AI systems to produce algorithmic bias.
osf.io/preprints/psyarxiv/rxu37_v1
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Jan Haaker
Simon van Gaal
3 months ago
Just out! Expectations modulate stimulus-evoked recurrent, but not feedforward, processing, and this is attention-dependent. NMDA-dependent feedback specifically supports perceptual integration (illusory contours), rather than mediating expectations (base rate).
www.jneurosci.org/content/46/1...
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Effects of Expectation, Attention, and NMDA Receptor Blockade on Feedforward and Feedback Processing
Perception is increasingly viewed as an inferential process wherein sensory inputs are integrated with prior expectations. We employed time-resolved decoding on electroencephalography (EEG) data ( n ...
https://www.jneurosci.org/content/46/12/e0674252026.abstract
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Jan Haaker
Miriam Klein-Flügge 🧠
3 months ago
🧠 Focused ultrasound changes emotional processing 🔊 In a new study published in Neuron today, we stimulated the human amygdala using transcranial ultrasound stimulation (TUS) and show it plays a causal role in detecting and resolving emotional ambiguity.
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Jan Haaker
MadScientist
3 months ago
"genAI can be used to create podcasts from a paper to teach st-" Let me stop you right there. Before you feed somebody's paper to a slop machine, invite that somebody to talk to your students about their paper. We're right here. We academics won't shut up about our work, man. 🧪
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Sjoerd Meijer
4 months ago
🧠 What makes threat memories so hard to forget? 🐍😱 Using focused ultrasound we provide causal evidence that the human amygdala drives rapid threat learning 🐍⚡ and determines how resistant those memories become to subsequent extinction 🐍🚫 🆕📄
www.science.org/doi/10.1126/...
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The human amygdala in threat learning and extinction
Ultrasonic neuromodulation of the human amygdala provides causal evidence for its role in forming persistent threat memories.
https://www.science.org/doi/10.1126/sciadv.aea8233
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Ultrasound stimulation of the amygdala slows threat acquisition and speeds up immediate extinction. Cool to see more TUS applications with neat controls (e.g., hippocampus TUS)
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4 months ago
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Jan Haaker
Lauren Atlas
4 months ago
It is so stimulating to be at the
#USASP
@usasp.bsky.social
annual meeting & to be reminded of the big picture & why pain science matters. We didn’t receive approval until after the conference had already started. We do better science when we can collaborate with & learn from our scientific peers.
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Jan Haaker
Tim Behrens
4 months ago
What are the systems in neuroscience that we really have something that we can call “explanation” at all relevant levels, other than reflexive feed-forward like circuits. Here are a few that I would argue are getting there. Obviously not complete explanations but genuinely satisfying.
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Dr. Helena Hartmann (she/her)
4 months ago
🌟 I am both a scientist and a science communicator 🌟 Never have I felt this more than this year, because the wonderful
#scicomm
team of the
@sfb-trr-289.bsky.social
is creating their first museum exhibit about treatment expectations for the MS Wissenschaft (
@w-i-d.de
), a traveling museum boat! 🚢
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Jan Haaker
Ulrike Bingel
4 months ago
Thrilled to see this amazing science communication endeavor come to life! Huge thanks to
@helenahartmann.com
and the
@sfb-trr-289.bsky.social
SC Team! Don’t miss the MS Wissenschaft when it’s near you!
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Luianta Verra
4 months ago
💥New paper out! Why do some people generalise threat more than others? We show that anxious people generalise more strongly, even after accounting for perceptual mistakes. A huge (!) thanks to
@ondrejzika.bsky.social
@nicoschuck.bsky.social
and
@bernhardspitzer.bsky.social
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An excellent talk by Sebastien Bouret to develop new ideas about the function of the locus coeruleus!
4 months ago
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Jan Haaker
Ole Goltermann
12 months ago
Serious concerns about a new cortical biomarker for pain sensitivity
jamanetwork.com/journals/jam...
We (with
@tspisak.bsky.social
,
@christianbuchel.bsky.social
) published a commentary on Chowdhury, Bi et al. (2025, JAMA Neurology) raising serious concerns about their reported results. 👇 1/13
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Concern About Predictive Performance of a Pain Sensitivity Biomarker
To the Editor Chowdhury et al1 evaluated a biomarker for pain sensitivity, combining peak alpha frequency and corticomotor excitability. The authors report outstanding performance (validation set area...
https://jamanetwork.com/journals/jamaneurology/fullarticle/2836397
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