Our multiverse analysis of associations between skin conductance and acute pain is published! >550 participants x 18 SCR pipelines = 1 winning approach to SCR analysis! (Ledalab + artifact detection). thread below. We hope others find this useful! Please RT :) journals.lww.com/pain/fulltex...

@alexanderhuth.bsky.social already suggested here on bsky that the reported findings can arise from noise alone. Simulations with 100% matched BOLD/metabolism signals reproduced their results. This motivated us to examine their publicly shared data & code. 👇 4/11

However, conclusions by Epp et al. go far beyond, claiming that ~40% of reported BOLD findings could be misinterpreted, broadly questioning >30 years of fMRI research (see their press release: shorturl.at/4FAMw). But does the data really support this? 👇 3/11

Epp et al. use quantitative fMRI to test whether + and - BOLD signals are concordant in sign with underlying metabolism. That this relationship is complex is long known and has been extensively studied, already shaping how fMRI findings are interpreted. (see www.nature.com/articles/s41...). 👇 2/11

A recent paper by Epp et al. in NN claimed that ~40% of reported BOLD findings could be misinterpreted. In our reanalysis, we identified several statistical issues that, in our view, undermine these conclusions. www.biorxiv.org/content/10.6... 👇 1/11

1/6 Our paper is out today in Nature Communications! From the SFB/TRR 289 Treatment Expectation @sfb-trr-289.bsky.social we show that temporal expectations shape somatosensory perception - for both painful heat AND non-painful cold stimuli.

Howard Fields was a great scientist and one of the pioneers unravelling the descending pain modulatory system. He was also interacting with human pain scientists and I vividly remember my visits to UCSF in 2013 during my sabbatical at Stanford to discuss ideas with him. He will be dearly missed.

This is the May cover of NN but it has already been debunked on biorxiv www.biorxiv.org/content/10.6... Such a clear statement about the ridiculous pace of publishing (not just NN).

Tagging @isnlab.bsky.social @stefaniebrassen.bsky.social @helenblank.bsky.social @janhaaker.bsky.social @christianbuchel.bsky.social @aulenkamp.bsky.social @wohrlab.bsky.social @sheddenmora.bsky.social @rief01.bsky.social and all other CRC members! 😍 Starter pack: go.bsky.app/TgjkCXL

It is with profound sadness that we share that Professor Andrea Evers passed away. Andrea was a visionary leader, a brilliant scientist, and a compassionate colleague. As we begin to process this immense loss, let us remember Andrea for her remarkable legacy and kindness she brought into our lives.

🚨 Fresh preprint w/ @helenblank.bsky.social! How does the brain acquire expectations about a conversational partner, and how are priors integrated w/ sensory inputs? Current evidence diverges. Is it prediction error? Sharpening? Spoiler: It's both.👀 🧵1/16 www.biorxiv.org/content/10.1...

I appreciate the effort in digging into this and doing the analysis. Very few people are spending the time to do it!

Any time a paper reports an AUC of 1.0 on test data, my hackles are raised. This commentary by @olegolt.bsky.social @tspisak.bsky.social @christianbuchel.bsky.social nicely dissects problems with a recently reported "biomarker" for pain.

Serious concerns about a new cortical biomarker for pain sensitivity jamanetwork.com/journals/jam... We (with @tspisak.bsky.social, @christianbuchel.bsky.social) published a commentary on Chowdhury, Bi et al. (2025, JAMA Neurology) raising serious concerns about their reported results. 👇 1/13

Very sad news! She was my dear desk neighbor at UCL for many years. She made outstanding contributions to the science of learning and memory, and the fact that one of her PhD students was awarded a Nobel Prize in 2024 further highlights her exceptional abilities as a mentor in the field of science.

Exciting PhD opportunities in various labs in Hamburg, including ours. Feel free to contact me regarding details. www.uni-hamburg.de/stellenangeb...

Excited about the next SIPS conference on all things #placebo and #nocebo in Krakow! For the second time, there will also be a (free!) summer school for Early Career Researchers on the two days before the conference. Be an early butterfly and register soon! @sfb-trr-289.bsky.social

Today we protest to support the future of the Netherlands. with more than 20.000 people we say 'Stop the cuts to science and science education!' #woinactie #dja

What a great decision! www.science.org/content/arti... Thank you Clarivate, it makes me want *even more* to submit my next paper to @elife.bsky.social !

I started (at @katesadlerphd.bsky.social's suggestion, thanks Kate for pushing me) a pain neuroscience and pain research starter pack. I am sure I have missed many people so if I missed you, I am sorry, but please just ask me to add you in the thread below and I will do that. go.bsky.app/KboKNhg

Hello new followers! We have positions available in my lab for one postdoc and 2-3 postbacs to start over the next year and lead studies on pain & emotion using high field MRI. Join us! www.nccih.nih.gov/about/jobs/p...

Breaking up with bad #science podcast. A science podcaster endorsing the world’s most prominent #neurobollocks is too much, even for a #therapist… Sorry Baby XoXo #neuroscience #TherapistSky #TherapistsConnect #NeuroTherapy #psychotherapy www.neuroscienceandpsychotherapy.com/post/bad-sci...

Check out our new review on "How control modulates pain" doi.org/10.1016/j.ti.... We have not only summarized many studies in this field, but also suggest that in the context of a Bayesian pain model, control might be mediated by changes in expectation.

Hi #Neuroskyence #PsySciSky Introducing our institute of Systems Neuroscience: This is our large magnet with the radio antenna. With this, several brains can look at one brain. And you can make nails on a thread fly - at least a famous physicist in the institute can make this happen.🧠🧲⚡

We are here! Thanks to all who provided us with codes 🙏

doi.org/10.1016/j.ne... Very interesting paper comparing rsfMRI, various FC parameters derived from task fMRI and task fMRI parameters for the prediction of behavior.

Check out our 🔥 preprint on paradoxical heat! Big shoutout to @agmitchell.bsky.social and the team for the awesome work 👏

Excited to be here!