tldr: in past 25 years annual incidence of psychotic disorders increased by 60% in 14-20 year olds, in Ontario🇨🇦; rates stable or lower among 21 to 50 y/o A few possible factors: ⬆️parental age, ⬆️substance use, maternal/neonatal health, other stressors). 🧪🧠 #neuroskyence www.cmaj.ca/content/198/...

Great analysis from an economical perspective on the issue of receiving psychotherapy when indicated!

First post of the year, new paper out today: we present possibly the biggest case of systematic Measurement Schmeasurement in tech use. It seems that most studies on gaming (videogame) addiction/disorder haven't measured gaming after all. This research took years, so long 🧵 doi.org/10.1098/rsos...

I've never experienced anything like this in my life, where people keep telling me that "we have to use AI or else we'll be left behind" but they don't actually tell me exactly what problem they are hoping to solve with the "AI" or how we would know it was useful. But we must use it! Apparently.

Finally got around to reading this great paper. A really insightful argument for treating psychedelic-assisted therapy as psychotherapy!

With Zalsupindole (see quoted skeet) and Bretisilocin (5F-MET; journals.sagepub.com/doi/10.1177/...) there are very exciting things happening in the psychedelic drug development world. 5F-MET especially might be well suited to psychedelic-assisted psychotherapy with a half life of 40-50 minutes!

Are you a journal editor in Psychology? There's a lot you can do to help support PCI Psych! PCI Psychology is a journal-independent peer review platform where journal editors like you evaluate and recommend preprints, that can then be published in PCI-friendly partner journals. 1/🧵 #PsychSciSky

Seeing lots of reactions to this compelling paper - showing VTA dopamine is linked to cue and outcome induced behavioral reactions: www.nature.com/articles/s41... I have some thoughts…

Results of the replication are in! Chocolate is more desirable than poop: Cohen's d_rm = 6.20, 95%CI [5.63, 6.78] N = 486, two single item 1-7 Likert scales of desirability. w/ @jamiecummins.bsky.social

Excellent opportunity to pursue a PhD on dissociative states with @susannahpick.bsky.social and me at the IoPPN @kingsioppn.bsky.social Reach out to us with any questions

Total wichtige Studie. Die Industrie ist hier nicht nur unglaubwürdig, sondern geradezu zynisch. In Schottland wurde der Mindestpreis, der sich dezidiert gegen den Konsum großer Mengen billigen Alkohols richtet, jahrelang von der Alkoholindustrie gerichtlich aufgehalten.

We often hear from reviewers: "what about demand effects?" So we developed a method to eliminate them. Something weird happened during testing: We couldn’t detect demand effects in the first place! (1/8)

It has often been suggested that psychotherapy works because patients expect it will work before they have even started treatment. But what if treatment expectations are an emergent phenomenon that develops in the course of psychotherapy and contributes to a successful outcome?

#Bewusstseinskultur #Rausch „Die Drogen langweilen uns mit ihrem Paradies” PDF-Volltext: rb.gy/h568tp

What can *genetic insensitivity to opioids* teach us about endogenous opioid function in humans? Fully funded position in Oslo (PhD student or postdoc) Interested in pain, mu/kappa opioids, behavioural genetics, RCTs, or related? Apply here: 2411.webcruiter.no/Main2/Recrui... Please RT for reach

Are interoception and mental health linked? Many assume so, with interoception even described as a psychiatric “p-factor.” But in our latest preprint, we were surprised to find little evidence for such a connection. www.medrxiv.org/content/10.1... 🧵 Thread with our reflections on the matter 👇

🍄 Our new living systematic review and meta-analysis on psilocybin for depression is out. Here's what we found and the open science infrastructure we built to support it 🧪🧵 www.medrxiv.org/content/10.1...

1. I need to recover this thread from X about a review on lithium in tap-water and suicide. It shows that papers aren't retracted despite being total nonsense

📣 Noch 2 Tage bis zum Bewerbungsschluss! Bitte teilen – wir freuen uns auf die Bewerbungen! 🤩

Bit of a quiet landmark this study. Offers significant evidence to suggest non hallucinogenic psychedelic analogs could be effective as antidepressants. Amazing stuff.

Huge congratulations to our two CRC members @labasedow.bsky.social and Marcel Wilhelm from @unimarburg.bsky.social for winning two out of four science slam prizes! 🥳🤯 Of course we also congratulate @ldruart.bsky.social and Pavel Goldstein for the other two awards - all super deserved! 🤩

Really happy to be able to present my Poster regarding placebo-induced psychedelic effects at #SIPSplacebo2025 Funded by the @sfb-trr-289.bsky.social

Really happy to have participated again. Always a fun challenge! @sfb-trr-289.bsky.social @sipsplacebo.bsky.social #SIPSplacebo2025

Huge thanks to Lene Vase for highlighting both our recent placebo meta-analysis and the patient advisory board ❤️ The meta-analysis: www.biorxiv.org/content/10.1... The patient advisory board: treatment-expectation.de/projekte-peo... @sipsplacebo.bsky.social #SIPSplacebo2025

Glad to see this paper out finally. Well done @trpwolff.bsky.social for driving it! I think this idea has potential for significant impact in psychedelic drug development. /1 🧵 👇 📄 doi.org/10.1177/2050...

✨ Job opportunity! ✨ We're currently seeking a Research Associate in Psychology for a new project led by @fieldmatt.bsky.social which will use machine learning to develop a better understanding of why many people drop out of treatment for gambling problems. More project info at: bit.ly/45WEyVb

PCI Psychology is here!! 🎉🥳 After over a year of hard work by so many people, we are thrilled to announce that we are open for submissions! Join us in making publishing more efficient, equitable, and open: psych.peercommunityin.org #PsychSciSky #scipub

An der @rptu.bsky.social wird eine neue W2-Professur "Klinische Psychologie und Psychopathologie" geschaffen 🎉 Wir freuen uns über zahlreiche Bewerbungen und stehen auf dem #dpk25 bei Fragen gerne zur Verfügung! jobs.rptu.de/jobposting/0...

Gerne weiterteilen und geeignete Kandidat:innen darauf aufmerksam machen! Neben Verfahrensoffenheit ist auch offen, ob Schwerpunkt auf Kinder & Jugendliche oder Erwachsene - oder eben über die Lebensspanne

Really proud that this paper got published: www.sciencedirect.com/science/arti... While I was only involved peripherally in the final publication, this paper is the result of a project I started during my master thesis 8 years ago! It's great to see continuous collaboration result in a cool paper.

“We argue that high-quality collective outcomes are endangered not only by self-interested individual defectors, but by ‘cartels’ of mutually satisfied mediocrities.” 👀 I’ve often referred to Gambetta’s book in the context of academic dysfunction. Very excited to discover more relevant work!

Great to see a psychedelic null result published in JAMA Psychiatry! "[...], repeated low-dose LSD administration was safe in an outpatient setting, but it was not more efficacious than placebo in reducing ADHD symptoms." (Strong Placebo response as well!) jamanetwork.com/journals/jam...

New blog post! In which I explain the issue with mediation analysis and sketch out one way to deal with the underlying causal inference problem -- in just a bit over 1,000 words! If you have never found the time to read up on this, now is your chance. www.the100.ci/2025/03/20/r...

🔥Frisch gedruckt im PTJ🔥: @tkaiser.science , Rafaële Huntjens und ich haben in dem Artikel gängige (Fehl-)Annahmen in der klinischen Praxis im Zusammenhang mit der Dissoziativen Identitätsstörung (#DIS) aus Sicht der Wissenschaft näher beleuchtet. Ein Thread 🧵: 1/

Our first qualitative study on the Flotatation experience as Preprint: "Silence, darkness, and gravity: A qualitative analysis of individual experiences during Floatation-REST". By Kristin Schiffer, Eric Pfeifer, Christine Stolterfoth, and Marc Wittmann osf.io/preprints/ps...

Hi everyone, if you are interested in #psychedelic-assisted therapy, we just published a new study: www.sciencedirect.com/science/arti.... Congratulations to Dr. Nathalie Rieser, who has done a terrific job spearheading this project.

I waited for this paper by @robinawester.bsky.social, @ehrenthal-lab.bsky.social et al. to appear and finally, it's there. A mixed-methods survey on how German psychotherapists engage in personalized treatment selection. The results are interesting.

It's out! Elated to share our latest work. I am incredibly proud of Ashley and the entire team. This study really brings together the best of everything we've been doing, and is the culimination of our research so far. It has everything - psychophysics, modelling, drug manipulation of intero!

🚨📃New Wassum Lab Paper📃🚨 Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇 www.nature.com/articles/s41... Free full text: rdcu.be/eaxEv

🏰 PhD position on computational modelling | collective dynamics | cultural evolution 🏰 Get in touch with any questions you might have and join me in beautiful Marburg! stellenangebote.uni-marburg.de/jobposting/c... (Deutsch) stellenangebote.uni-marburg.de/jobposting/3... (English)

Scientific publishing cannot be free but an annual $2.5 billion seems excessive to me

"...ergibt sich [...] im Durchschnitt ein personeller Mehrbedarf im ärztlichen und pflegerischen Bereich von 103 Prozent..." Ach... #Psychotherapie #Psychiatrie www.aerzteblatt.de/archiv/24254...

"Missing outcome data in randomised clinical trials of psychological interventions: a review of published trial reports in major psychiatry journals"

New results for a new year! “Linking neural population formatting to function” describes our modern take on an old question: how can we understand the contribution of a brain area to behavior? www.biorxiv.org/content/10.1... 🧠👩🏻‍🔬🧪🧵 #neuroskyence 1/

How did people get significant positive effects for so long? Small groups (N<10 is typical), p-hacking, harking. How much time, money have we wasted on that technique? (I was part of the problem) I hope people starting Focused Ultrasound are taking notes (but I see the same mistakes being done)

Wow! I think this is one of the best (and most beautiful) demonstrations I've seen of the exquisite structure and specificity of neural circuits!

"Several scientists I spoke to whose work appears in the book ['The Body Keeps the Score'] say van der Kolk mischaracterizes their research and steers survivors away from treatments that might help them." @araldob.bsky.social, @tflangkaas.bsky.social

The proposition facing patients for most drug trials isn't "you will be given placebo, or some miracle drug" It's "you will be given the standard of care you would receive if not enrolled on the trial plus a placebo, or that standard of care plus a new drug that may or may not be effective"

I agree w/ the problem description, but I'm skeptical of the proposed solution. Yes, the efficacy of treatment is to some extent substantially overestimated (due to publication bias, risk of bias etc.). However, the evidence for the effectiveness of universal prevention strategies is *even worse*.

Gemütlich im Mittelbau #einkuscheln?! Ihr wisst: Ich habe #IchBinHanna gestern im Wissenschaftsausschuss des NRW-Landtags vertreten. Was ich da alles gesagt hab? 1 🧵! Da ich vermute, dass Euch das besonders interessiert, fange ich mal mit meiner Reaktion auf das Einkuscheln an. (1/8)