I wonder if my family will stop thinking I’m daft as a brush now I am Prof of Cardiorespiratory Medicine in Cambridge? Scratch that. I already know the answer.

www.jci.org/articles/vie.... Our attempt to take in end-organ dysfunction with the liver as our focus in PAH/RV Failure. @jci.org @natrevgastrohep.nature.com @the-asci.org @mark-toshner.bsky.social

Paper drop where we question the mechanism of action of sotatercept. Think this will only get more important as the drug does lots of interesting things. pubmed.ncbi.nlm.nih.gov/42160453/

You will not find a clearer thinker and good human being to boot. Medical leadership is painfully difficult and unfortunately full of mediocrity at an important time for the profession. Vote for someone better! bsky.app/profile/drlk...

An excellent candidate IMO, careful, thoughtful, and passionate about training enough high quality doctors.

Voting opens today for @rcphysicians.bsky.social elections. I am standing for Vice President for Education and Training. It's the first elections where Members will also be able to vote. Please encourage all eligible to exercise their franchise. More about me here: tinyurl.com/22j7nypk

The Blue Journal thanks Eckart De Bie, MD, MPhil, for his contribution to the January issue Inflammation and Obesity Correlate in Pulmonary Hypertension but Associate with Diverging Outcomes @mark-toshner.bsky.social academic.oup.com/ajrccm/artic...

Every once in a while awards committees get it right! If there is a more deserving person out there of this than Marc Humbert, I don’t know them! eur03.safelinks.protection.outlook.com?url=https%3A...

The @washingtonpost.com story on Tylenol & autism leaves out a MAJOR 2.5M sibling-controlled study of children in Denmark, which "found no evidence that acetaminophen use during pregnancy was associated with children’s risk of autism, ADHD or intellectual disability." jamanetwork.com/journals/jam...

After our mammoth international patient engagement work- some actions for the global community to consider pubmed.ncbi.nlm.nih.gov/40662200/

The United States has recorded its highest annual measles cases in 33 years. The milestone marks a public health reversal in defeating a highly contagious, vaccine-preventable disease as the anti-vaccine movement gains strength.

First ever international survey of patients with pulmonary hypertension. Wonderful collaborative work. Lots of important and useful insights. t.co/XTvpbS4g8Y

My excellent student winning the best type of award. One for actually remembering the patient in amongst our research! bsky.app/profile/camb...

AND FINAL CONGRATULATIONS to @cam.ac.uk MPhil student Vidisha Handoo, whose poster was voted the best of those on display at last week's Cambridge #PPI Showcase day @angliaruskin.bsky.social @cuh.nhs.uk Thanks to ALL our presenters & poster submissions, you were all great! 3/3

Glasgow. Where the people are funniest because the weather is no joke. Good to be home!

I’m in the Guardian today, arguing that we should stop them all-class mental health lessons in schools I've thought very carefully about ‘going public’ with this, because it's a sensitive argument to make, especially in the face of so many young people struggling. (cont 🧵) tinyurl.com/vun92cz7

www.ahajournals.org/doi/10.1161/.... Our most recent work attacking RV failure! @mark-toshner.bsky.social @ahascience.bsky.social @ahajournals.bsky.social

That joyous moment when you get rid of the 🐵 on your back, AKA submitting that 27 page rebuttal after 9 months of revisions… 🎉 images.squarespace-cdn.com/content/v1/5...

⭐️Meet the speaker⭐️ We’re delighted to have @mark-toshner.bsky.social joining #DDDS2025, who will be speaking on 'How to define or prove disease modification'.

I think most senior doctors in UK in positions of importance/power have just turned away rather than consider how terribly demoralised the trainees are by the current awful system.

Quite a stunning result this. Sotatercept in severe pulmonary arterial hypertension www.nejm.org/doi/full/10....

‘My dad is so cringe’. I’ve reached peak parenting

🎥 Highlights from yesterday's VPD-HLRI Monthly Seminar! Great talks by Prof. Jason Gill from @uofglasgow.bsky.social and our very own Prof. Murray Clarke. Thanks to our speakers and attendees! #HLRI #MetabolicHealth #VascularInflammation @cambridgeuni.bsky.social @murrayclarkelab.bsky.social

Just gave a talk with the absolute brightest lights I’ve ever had blinding me from back of auditorium. Really affected my game!

The view from Adelaide convention centre is a bit special eh?!

Very excited to share our work in Imatinib in PAH. Read on for the TLDR t.co/q7Uyg8uRdJ

Very excited to share our work in Imatinib in PAH. Read on for the TLDR t.co/q7Uyg8uRdJ

Longer term post-hospital morbidity and mortality following admission with Covid-19: A systematic review and meta-analysis. publications.ersnet.org/content/erjo... @charlottesummers.bsky.social @mark-toshner.bsky.social @lukeflower.bsky.social

“Johns Hopkins has bet very heavily on a century & a quarter of partnership with the federal government,” said Dr. Theodore Iwashyna, a critical-care physician… “If the federal government decides it doesn’t want to know things anymore, that would be bad for Johns Hopkins & devastating for Maryland.”

In other news- NASA to investigate flat earth claims www.nytimes.com/2025/03/07/h...

My great grandparents were immigrants to the UK (on both sides). At dinner with my 85 yr old uncle he told me a story that has been sitting with me and I’d like to share.

My great grandparents were immigrants to the UK (on both sides). At dinner with my 85 yr old uncle he told me a story that has been sitting with me and I’d like to share.

Edinburgh airport is, I note, taking a principled stand against US intolerance 🤣😂

This thread is a genuine off- the-cuff work of art

Edinburgh airport is, I note, taking a principled stand against US intolerance 🤣😂

Pulmonary hypertension peeps- I think we have produced a pretty definite paper nailing right heart structure, function and clinical outcomes? What do you think? t.co/B5yED7ypmI

Formal events and weddings. Definitely not enough being done to start conversations about the Witchcraft Act 1563

I really like this tartan, but imagine having to explain why you are wearing it at your friend’s wedding… wildhunt.org/2025/02/newl...

I’ve thought long and hard and here is my greatest achievement. I’ve had this badge for almost 20 years 🤣😂🤣

It never ceases to amaze how ‘bus-like’ journal submissions are. Have been submitting papers continuously for about 8 months with nothing much landing. 3-4 landed this week within 48hrs of each other. It’s a conspiracy… I stress test my mental health!!

Google rolling back on this slowly I see

If there are any editors out there hanging on to one of my manuscripts that aren’t about to be rejected, cheer me up this afternoon by pinging the email (and hold on to the rejections til Monday)

Stolen from LinkedIn... 🧪

Asking for a friend. If your wife bought these socks at Xmas and you accidentally wear them to work, would an HR complaint be A) upheld and rightly so B) dismissed out of hand…

The curse of full confidence strikes again…

Is there any public phrase less inspiring of confidence than “I have full confidence in…”

Middle age in the gym is just twinge roulette. Shall I keep going through this one or is it the one that cripples me and I can’t put in my socks tmw… do I feel lucky, punk. 🔫

Is there any public phrase less inspiring of confidence than “I have full confidence in…”

Winter on the bike!