Viejo-Borbolla Lab
@viejoborbolla.bsky.social
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Viejo-Borbolla Lab
Memorial Sloan Kettering Cancer Center
about 2 months ago
New in
@natbiotech.nature.com
: a team led by scientists at MSK and āŖUniversity of Toronto have developed a new platform to facilitate the study of RNA-biding proteins (RBPs) across hundreds of species of plants, insects, and animals.
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A resource of RNA-binding protein motifs across eukaryotes reveals evolutionary dynamics and gene-regulatory function - Nature Biotechnology
RNA-binding motifs in eukaryotic proteins are presented in a comprehensive resource.
https://www.nature.com/articles/s41587-025-02733-6
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In the last day of the
#IHW2025
Josi Schenk funded by
@resist-cluster.bsky.social
gave a great explanation on how VZV modulates One Carbon metabolism in epithelial cells. Inhibition of this pathway blocked VZV, HSV-1 and HSV-2 infection, providing novel ways to target these viruses
about 2 months ago
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Nina Plückebaum gave a great talk at the
#IHW2025
showing the results of a bindings screen performed with the RL11 protein family of
#human_cytomegalovirus
and 80% of all human single transmembrane proteins revealing a novel viral strategy to modulate natural killer cell activity
about 2 months ago
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Today there were many interesting talks at
#IHW2025
, including one from Nadine Brückner who gave a great talk in the VZV Satellite Workshop exploring how VZV is repressed during infection of neuron-like cells.
2 months ago
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On my way to the
#IHW2025
in Berlin. Looking forward to meeting many friends and colleagues and to learn more about herpesviruses
2 months ago
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Last Sunday we went hiking in the Deister, nice hills close to Hannover. It was a very nice day despite the heat.
3 months ago
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Viejo-Borbolla Lab
International Cytokine & Interferon Society (ICIS)
4 months ago
Don't forget š Abstract deadline for poster or oral presentations is June 18. Please repost to your network to spread the word! More info or register at
seattle.cytokinesociety.org
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Viejo-Borbolla Lab
4 months ago
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GrandmaDeb
4 months ago
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It was a great experience to participate and present our data in the last GRC viruses and cells conference organized by
@sesmalab.bsky.social
. Looking forward to more exciting science and collaborations!
4 months ago
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Wonderful news! This will allow
@resist-cluster.bsky.social
to better understand why some individuals are highly susceptible to infectious diseases while others arenāt. Thanks to everyone involved in the application and evaluation process!
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4 months ago
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Donāt miss the
@resist-cluster.bsky.social
seminar by
@richstanton.bsky.social
this coming Thursday!
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5 months ago
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Viejo-Borbolla Lab
Exzellenzcluster RESIST
5 months ago
We are very much looking forward to the two lectures on Wednesday (!), 14 May from 12.30 pm by Prof. Donna Neumann and Prof. Robert Kaletja, University of Wisconsin-Madison. Come in large numbers to lecture hall Q at the MHH! We will offer snacks at 12.00 PM
www.resist-cluster.de/en/veranstal...
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RESIST Seminar guest lectures by Prof. Neumann and Prof. Kaletja
Exciting topics, interestingly presented: Every first and third Thursday (except during school holidays), RESIST scientists or top-class researchers from external institutions present their topics at ...
https://www.resist-cluster.de/en/veranstaltung/resist-seminar-guest-lectures-by-prof-neumann-and-prof-kaletja/
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Thanks
@beatesodeiklab.bsky.social
for your kind words. It was a great experience talking about SPR in the āHow toā¦ā seminar series organized by the ACHIEVE Academy of the
@gesvirologie.bsky.social
. I especially enjoyed the discussion part of the event
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5 months ago
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Viejo-Borbolla Lab
Nature
6 months ago
"This is my home - I really love my country. But a lot of my mentors have been telling me to get out, right now" 75% of US scientists who answered our poll are considering relocating. Read the full story:
https://go.nature.com/3QS4TLC
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Viejo-Borbolla Lab
Nature
6 months ago
An immigration crackdown in the United States is rattling the global research community, with high-profile detentions and deportations of academics stoking fears even for travellers with valid entry documents.
https://go.nature.com/3FG63rf
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āAnxiety is palpableā: detention of researchers at US border spurs travel worries
Nature - Several high-profile incidents in the past month have scientists on edge.
https://go.nature.com/3FG63rf
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Viejo-Borbolla Lab
Thiago Carvalho
6 months ago
'Among those NIH-funded projects are more than 100 clinical trials that now may be forced to halt abruptly, agency officials told me. And those officials expect further orders to cancel hundreds more.'
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The NIHās Most Reckless Cuts Yet
Ending clinical trials with no warning can put patients at risk.
https://www.theatlantic.com/health/archive/2025/03/trump-nih-clinical-trials-patient-safey/682217/?gift=AiEIjABLdW1e9gDdGHt0QmSvQmmV_tyfbDLHJBkez6Q&utm_source=copy-link&utm_medium=social&utm_campaign=share
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reposted by
Viejo-Borbolla Lab
Nature
6 months ago
š§Ŗ A paralysed man can stand on his own after receiving an injection of neural stem cells to treat his spinal cord injury
https://go.nature.com/4jaZ3RB
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Paralysed man stands again after receiving āreprogrammedā stem cells
Nature - Another man also regained some movement, but two others experienced minimal improvement.
https://go.nature.com/4jaZ3RB
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Viejo-Borbolla Lab
Nathan Kalman-Lamb
6 months ago
Hundreds of international students have just received an email telling them their visas have been revoked. The ājustificationā is campus activism or social media posts.
timesofindia.indiatimes.com/world/us/hun...
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Viejo-Borbolla Lab
WHO
6 months ago
At least 95% measles vaccine coverage is needed in all communities to prevent
#measles
and stop outbreaks. The only way to prevent measles? Two doses of measles vaccine. Letās close the gap and keep measles away!
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Viejo-Borbolla Lab
Doctors Without Borders
6 months ago
Terrible news today of a powerful Myanmar earthquake that shook communities across Southeast Asia. Our staff working in Myanmar and Thailand are safe and accounted for. Swift and unhindered access to the affected areas is critical. More here:
www.doctorswithoutborders.org/latest/msf-r...
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Viejo-Borbolla Lab
Matt Novak
6 months ago
No food or supplies have been allowed into Gaza in over three weeks
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Hunger looms again in Gaza as WFP food stocks begin to run out | World Food Programme
GAZA, Palestine ā Hundreds of thousands of people in Gaza are again at risk of severe hunger and malnutrition as humanitarian food stocks in the Strip dwindle and borders remain closed to aid. Meanwhi...
https://www.wfp.org/news/hunger-looms-again-gaza-wfp-food-stocks-begin-run-out
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Viejo-Borbolla Lab
Constantine
6 months ago
We are very close to a near cure for two of the highest-mortality cancers we know: glioblastoma and pancreatic cancer. These are both mRNA based treatments which are losing their funding during stage I and II trials. Thousands will die needlessly because of this motherfucker and his lies.
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Viejo-Borbolla Lab
Nature
6 months ago
A measles outbreak in the United States is growing, with no end in sight. We asked specialists how bad things could get.
https://go.nature.com/4kOtwXe
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Measles is surging in the US: how bad could it get?
Nature - Researchers flag groups that should get an extra dose of measles vaccine as case numbers continue to rise in Texas and neighbouring states.
https://go.nature.com/4kOtwXe
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Viejo-Borbolla Lab
Jenny Fields
6 months ago
This broke my heart when I entered the bookstore. I was compelled to take a photo because I canāt believe weāre here. Thank you Barnes & Noble in Wareham, Massachusetts for placing it as first table when you walk in.
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It is essential to keep funding the NIH
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6 months ago
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Viejo-Borbolla Lab
Beate Sodeik
6 months ago
Discussions on bird flu in the US. 𤨠If itās not human and animal health for you, if itās not ethics for you, itās at least economics. š¤·š»āāļø
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Helen Branswell šØš¦
6 months ago
The former head of PEPFAR pleads for the preservation of the lifesaving program.
@cohenjon.bsky.social
speaks with John Nkengasong.
www.science.org/content/arti...
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Outgoing head of heralded U.S. global HIV/AIDS program urges Trump to reverse cuts
John Nkengasong, who had helmed PEPFAR since 2022, says āhistory will remember we showed humanityā
https://www.science.org/content/article/outgoing-head-heralded-u-s-global-hiv-aids-program-urges-trump-reverse-cuts
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Viejo-Borbolla Lab
Lucas Mendes-Monteiro
6 months ago
Excited to share an Opinion piece that I wrote with my supervisor,
@viejoborbolla.bsky.social
, now published in Trends in Immunology! We discuss how viral IFNγ-binding proteins might provide mechanistic insights into uncoupling IFNγ-mediated gene expression.
www.sciencedirect.com/science/arti...
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It was fun to write this Opinion piece together with
@lucasmendesm.bsky.social
where we suggest strategies to modify interferon gamma to improve its potential applications in the clinic. Just published at
@cp-trendsimmuno.bsky.social
!
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6 months ago
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Great talk by
@lucasmendesm.bsky.social
at the meeting of the
@gesvirologie.bsky.social
showing how glycoprotein C expressed by varicella zoster virus modulates the activity of interferon gamma!
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7 months ago
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With this skin organoid model presented by Manja Czech-Sioli she can monitor cell-specific responses to virus infections in a 3D context. Great work! Looking forward to collaborate with Manja studying VZV infection of skin and neuronal organoids in
@deep-dv-for5200.bsky.social
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7 months ago
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Great talk by
@josephineschenk.bsky.social
at the
@gesvirologie.bsky.social
meeting in Hamburg! ššš
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7 months ago
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Looking forward to learning about
#virology
and meeting many friends and colleagues
@gesvirologie.bsky.social
7 months ago
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Viejo-Borbolla Lab
Nature
7 months ago
Repeated threats to research funding and the mass firings of federal workers have pushed some scientists to take on unfamiliar roles as activists, speaking at rallies, calling legislators and forming new pressure groups.
https://go.nature.com/4bt2EI8
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US science is under threat ā now scientists are fighting back
Researchers are organizing protests and making their voices heard as Trump officials slash funding and lay off federal scientists.
https://go.nature.com/4bt2EI8
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We are on our way to the meeting of the German Society for Virology
@gesvirologie.bsky.social
. If youāre attending, donāt miss the talks by
@lucasmendesm.bsky.social
,
@josephineschenk.bsky.social
and
@ninaplueckebaum.bsky.social
, as well as Nadine Brücknerās poster
7 months ago
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Viejo-Borbolla Lab
Eric Topol
7 months ago
Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter
www.nytimes.com/2025/03/01/u...
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Congratulations George and Katja!
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7 months ago
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Congratulations to
@kreylab.bsky.social
for this great work. And thanks for bringing us on board! Always a pleasure to work with you
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7 months ago
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Viejo-Borbolla Lab
Kreylab
7 months ago
Happy to see this study published, a great collaboration between structural, molecular and clinical virology labs! We describe neutralizing antibodies targeting the Hepatitis E virus capsid protein that distinguish between infectious particles and antibody decoy.
www.nature.com/articles/s41...
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Broadly neutralizing antibodies isolated from HEV convalescents confer protective effects in human liver-chimeric mice - Nature Communications
HEV-specific antiviral treatment is still lacking. Here, the authors functionally and structurally characterize broadly neutralizing antibodies isolated from HEV convalescent individuals and show that...
https://www.nature.com/articles/s41467-025-57182-1
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Really awful news for science and society
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7 months ago
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Viejo-Borbolla Lab
The New York Times
7 months ago
Roberta Flack, the magnetic singer and pianist who was one of the most popular artists of the 1970s, died on Monday at 88. Flack was known for her majestic anthems like āKilling Me Softlyā and āThe First Time Ever I Saw Your Face.ā
nyti.ms/4h1KzSh
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Nature
7 months ago
Update: A block on NIH's new policy to slash billions of dollars of research-overhead costs has been extended by a federal judge. The block was set to expire Monday.
https://go.nature.com/3XgyvWn
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āDevastatingā cuts to NIH grants by Trumpās team put on hold by US judge
The ruling temporarily halts a policy slashing research overhead costs in 22 states, which filed a lawsuit against the biomedical agency.
https://go.nature.com/3XgyvWn
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Viejo-Borbolla Lab
Science Magazine
7 months ago
Already bruised by the Trump administrationās first round of firings of federal workers, employees at NIH faced more bad news. NIHās 27 institute directors were told this week that the agency must cut staffing back to 2019 levels, or at least 10% below its 2024 tally.
scim.ag/3EP8gjy
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More NIH job cuts coming? Agency's scientists already reeling after week of firings
NIH is appealing loss of some lab leaders among in-house research program while bracing for the next actions from the Trump administration
https://scim.ag/3EP8gjy
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Happy to share our publication in
#PlosPathogens
investigating repression of varicella zoster virus in neuron-like cells:
journals.plos.org/plospathogen...
Thanks to
@dandepledge.bsky.social
and other colleagues for their contribution!
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Repression of varicella zoster virus gene expression during quiescent infection in the absence of detectable histone deposition
Author summary Varicella zoster virus (VZV) establishes latent infection exclusively in human neurons. This phase of infection is characterized by restricted viral gene expression, lack of detectable ...
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012367
7 months ago
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Viejo-Borbolla Lab
Jeff (Gutenberg Parenthesis) Jarvis
8 months ago
Their aim is nothing short of a new Dark Ages. Anti-science, anti-education, anti-democracy, in favor of needless human suffering. NIH cuts billions of dollars in biomedical funding, effective immediately
www.washingtonpost.com/health/2025/...
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NIH cuts billions of dollars in biomedical funding, effective immediately
The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.
https://www.washingtonpost.com/health/2025/02/08/nih-cuts-billions-dollars-biomedical-funding-effective-immediately/
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Mia Farrow
8 months ago
NIH has cut billions of dollars in biomedical funding, effective immediately The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.
www.washingtonpost.com/health/2025/...
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NIH cuts billions of dollars in biomedical funding, effective immediately
The move halts a large slice of money for most universities and research institutions virtually overnight, imperiling vital research in everything from cancer to heart disease.
https://www.washingtonpost.com/health/2025/02/08/nih-cuts-billions-dollars-biomedical-funding-effective-immediately/
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Nina Plückebaum successfully defended her PhD today. Her work during the last four years as well as her defense today were outstanding. Iām extremely happy for her and proud of her achievements.
8 months ago
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