Serious scholars have examined what happens when we change the number of H1-B visas issued. Cities that get more H1-B immigrants subsequently see the wages of natives *rise* substantially. Skilled immigrants bring new ideas, fill labor shortages and make us all more productive.

lots of people saying that ACIP voted against the MMRV vaccine which is not really what happened 1) they voted to not recommend MMRV and instead to get MMR and V separately 2) they voted to keep the MMRV under coverage for the Vaccines for Children program 3) they seem confused by their own votes

The world’s first successful treatment of a patient with a personalized CRISPR gene editing therapy was carried out by a team at Penn Medicine and CHOP. This history-making breakthrough involved a child diagnosed with a rare genetic disorder. Read More: https://bit.ly/3Fd0Kzp

Children will die because of RFK Jr. Others may lose hearing or vision. Many more will suffer a horrible bout of illness for a week or more for no good reason. thehill.com/policy/healt...

This graph shows a U.S. public health triumph: near-elimination of pediatric hepatitis B through universal birth vaccination. After 30 years of extraordinary progress, ACIP tomorrow considers dismantling it. Medical justification: none. Consequences: catastrophic. www.cdc.gov/acip/downloa...

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We're witnessing the most aggressive, fanatical crackdown on free speech in my lifetime. The speed and breadth of government censorship and private sector and nonprofit capitulation has been astonishing. As has the lack of urgency/silence from people who've long claimed to care about this stuff.

Posobiec - whose ties to white supremacists are legion - wrote a book last year called “Unhumans” in which he labeled half the country UNHUMAN It is language designed to inspire political violence yet our cable news channels have made him a talking head about political violence

Reducing access to abortions ... - increases families' economic hardship, - increases families' debt, - increases income inequality, - increases housing insecurity, and - increases financially motivated crime rates.

“An extra six months, an extra year, a possible lifetime: That’s time that my talented 12-year-old son was denied. In his last months, Aryeh talked enthusiastically about starting middle school with his friends; about his upcoming bar mitzvah, which he began preparing for but didn’t celebrate…” 💔

When the world’s leading science journal is publishing how-to’s for top scientists to leave your formerly world-leading science enterprise, you’ve done something wrong. It’s not too late to reverse course, although the damage already done will reverberate for decades.

Some personal news: I've been fired from the Washington Post in the aftermath of the Charlie Kirk shooting. Thread incoming. substack.com/@karenattiah...

The First10EM Research Roundup for September 2025 It has been a while since I have critically appraised. Life without medical journals is sort of nice, but I guess it just isn’t me, so I am back and nerdier than ever. That means there are some strange selections this time around, but there are…

A couple of weeks later, and eight custom security rules later, my website traffic is successfully managed. Bots were overwhelming it, and the worst offenders were pretending not to be bots (fake referrers, fake user agents)—I'm gonna assume those are AI scrapers. Now they're throttled and blocked.

Hey, Cloudflare gave me full access to their suite of services via Project Galileo, their program to protect human rights, civil society, journalism, and democracy websites, so that means my highest-traffic website is now better protected. That was nice of them.

Crawlers have been hammering on my websites for the past few months, ignoring robots.txt, and it's worse every week. I didn't think I needed to design any of these for the DDoS-like traffic spikes, e.g. 17 GB retrieved from one EC2 instance in just 20 minutes this week. That gets expensive fast.

korean reporting is nightmarish on the conditions Korean workers were contained in

Another important thing to remember about the model of federal funding that has existed is that it was decentralized and there was no assumption about where discoveries could be made. Despite all the double speak about “gold standard science,” the current regime wants to politicize and centralize it

An apt comment from Harold Varmus in this piece: ‘Running a lab is not like running a clothing store, where if your sales are down you can bounce back. You are dealing with highly trained people and projects which, when stopped for a short time, are ruined.’

There’s also this guy on Twitter who is trying to get an army officer fired for sharing Kirk statements without comment, and I am fascinated by how they refuse to see the disconnect in “Charlie was a hero and you’re a monster for accurately quoting him”

Butler and others targeted were given no info about the nature of the claims against them and the university suspended normal processes for reviewing complaints, they said: "That means allegations sent to the administration, even anonymous ones, were simply forwarded without having been adjudicated

“As of this writing, some 40% of Americans will be diagnosed with cancer at some point in their life… Now an extraordinarily successful scientific research system — one that took decades to build, has saved millions of lives and generated billions of dollars… — is being dismantled before our eyes.”

We invest 9X less per child-year in care & education in the first 5 years of life than the next 13. This gap in public investment is why K12 is free for parents & early care & education is expensive. www.hamiltonproject.org/publication/...

Can economic opportunity lower mortality? Exploiting the fracking boom: job growth lowered medically treatable deaths (e.g. cardiovascular), likely via increased insurance coverage, but had no effect on external causes such as Deaths of Despair. www.journals.uchicago.edu/doi/10.1086/...

The CDC has quietly and drastically scaled back the country’s most comprehensive system for tracking the food-borne illnesses estimated to sicken millions of Americans each year.

100% preventable because #vaccineswork

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If you only condemn violence against a member of your group (however defined), you don't really oppose political violence.

Horrific terrorism. Strength and peace to the Kirk family. People from all corners of US need to join hands, speak up, & act together against the use of violence to advance a political agenda.

My feed is almost entirely people condemning violence and telling others not to celebrate this.

Violence is never the answer.

This is the single biggest thing, as a small business owner, that keeps me awake at night. More than anything else, this might be what drives me out of running Extra Points

PARC Research Associate, Mark V. Pauly, was quoted in this Newsweek article: “How Health Insurance Rates Could Rise in Florida in 2026.”

Northern Ireland man from Lisburn kidnapped by Trump’s Ice raids because he “looked like a Mexican”. He had the correct visa, all his documents. He’s never been in trouble with police. Held in terrible conditions. A fellow captive couldn’t get his medication and dropped dead of a heart attack

Up to 40% of Hepatitis B infections are acquired in childhood. There is a 90% likelihood of developing chronic infection (rather than clearing the infection) if it is caught in infancy, and up to a 50% likelihood if caught before age 6. Chronic Hepatitis B causes liver failure, cancer, and death.

Here's a report on this: news.bloomberglaw.com/us-law-week/...

No one would be confused about what is happening here if they saw it in another country.

The House spending panel rejected a 40% NIH cut, keeping its 2026 budget at ~$47B and all 27 institutes intact. ARPA-H would drop 37%, CDC 19%. The bill moves to the full Appropriations Committee Sept. 9 at 5pm EST. PRIM&R will continue to monitor this developing legislation. https://bit.ly/4ghne0b

/9 By the way - we should also fight the inclination to abandon the rule of law because bad people are cynically abusing it. First, while bad things happen on a national scale, every day on a micro scale advocates use the rule of law to fight injustice and improve lives.

/5 SCOTUS' discretionary intervention for President Trump to enable his unchecked powers -- combined with its non-discretionary expansion of his powers in cases like the immunity case -- have to me taken this beyond the space where tradition or politesse justifies making their arguments for them.

SSA's inspector general just completed an investigation on the prevalence of direct deposit fraud by phone, and found only about $2M in fall 2023, in a program that paid out $1.5 TRILLION. Over the course of a year, that's less than one-thousandth of one percent. 2/ oig.ssa.gov/assets/uploa...

Social Security's new policy on direct deposit is forcing nearly 2M older/disabled ppl to visit offices in person, leading to 1M wasted hours of drive time alone. VP Vance & others claimed it was to "prevent fraud." Now we know exactly how hollow those claims are. 1/ www.cbpp.org/blog/nearly-...

Massive privacy and security risks here as well.

🧪 I’m thrilled that @amia.org has compiled its inaugural starter pack! Follow all these pioneering researchers and clinicians shaping the future of medicine through their work in medical AI, clinical innovation, digital health policy, and patient advocacy. #MedSky #WhyInformatics #MedAI 🩺💻

A substantial part (but not all) of this increased investment is multi-year funded grants. My current estimate is that multi-year funding has been used in lieu of ~2400 annually funded grants that could have been made. 2/2

Updated update I downloaded the data from NIH Reporter too soon. The large end of the month update had not occurred. Here are the results as of this morning. NIH grants management staff have been busy making awards. 1/2

It his me hard in the emergency doctor feels as well. I’d never seen so many healthy 30 something’s struggling to breathe since the pre-vaccine pandemic.

v1.108 is rolling out today 🚚 Now live, at long last: Bookmarks, aka Saved Posts. For all those posts you'll definitely plan to come back to! Update the app and give it a try. The button is right down there 👇

Science that will never happen.

Today I introduced smallpox eradication in the vaccines class I’m co-teaching w/ @jackiantonovich.bsky.social A public health hero I learned about prepping for this class is Benjamin Rubin. He developed the bifurcated needle, & waived all royalties for needles manufactured under contract w/the WHO.