Question Mark xkcd.com/3143/

Happy to share our recent paper, led by Elias Erny: 👉 Endothelial cell stop proliferating in heart failure despite VEGF ⏫ 👉 transcription factors TCF19 and ATAD2 control endothelial cell proliferation and angiogenesis rdcu.be/eGYpJ Big thanks to all co-authors for the great collaboration #SFB1425

This!

Our latest preprint from the lab is now online: - single nucleus RNAseq comparison of aldosterone/salt vs high fat diet/L-NAME induced HFpEF - fibroblast specific MR knock-out dx.doi.org/10.21203/rs.... We are looking forward to your thoughts and comments!

Enjoying excellent presentations and meeting with colleagues and friends at International Aldosterone Conference at San Francisco. Can't wait to see you again in Rome later this year! admire-network.org/2025/06/02/a... @endocrinesociety.bsky.social

Extracorporeal cardiopulmonary resuscitation for refractory cardiac arrest CCR Journal Watch - tracking the critical care literature daily https://criticalcarereviews.com/latest-evidence/journal-watch

Happy to share our recent review article on Extracorporeal Cardiopulmonary Resuscitation in refractory cardiac arrest published in @lancetrespirmed.bsky.social covering all aspects and recent evidence of #ECPR for in-hospital and out-of-hospital cardiac arrest #OHCA #IHCA Open Access bit.ly/3HjVSsV

Abstract submission for the #ESAC2025 European Aldosterone Conference in Rome will open from June 1st to July 15th. Looking forward to your submissions!

Congratulations! @cibss.bsky.social @uni-freiburg.de

#SpatialTranscriptomics 👤 #Cardiomyopathy #HeartFailure GeoMx Cardiomyocyte #EndothelialCell Fibroblast segmented 44👤🫀 #TissueMicroArray #MyocyteDisarray HCMpEF➡️⏬ribosome #CardicFibrosis➡️⏫ACKR1+PLVAP+CCL14+ endothelium UCHL1 PFKFB2 for HF progression #EHJ 2025 academic.oup.com/eurheartj/ad...

#Aldosterone alters cardiomyocyte states and changes cell-cell interactions, finally leading to atrial myopathy and atrial fibrillation. www.ahajournals.org/doi/10.1161/... #afib Shout out to David Meral de.linkedin.com/in/david-mer...

New insights from the German VA-ECMO registry: Clinical use and predictors of outcome in venoarterial extracorporeal membrane oxygenation. link.springer.com/article/10.1... @tobi-wengenmayer.bsky.social

#Mechanobiology #RigiditySensing Cellular mechanosignaling for sensing and transducing matrix rigidity #YAP/TAZ #Piezo Mechanometabolism Substrate with tunable stiffness Cynthia Reinhart-King lab #CurrOpinCellBiol 2023 www.sciencedirect.com/science/arti...

Meta analysis suggests benefit of prone positioning for patients on #ECMO - RCT needed for definite answers. link.springer.com/article/10.1... @tobi-wengenmayer.bsky.social

It takes excellent research to move intensive care medicine forward: Happy to see exciting data, lively discussions, and many new project ideas at IMIT Science Day 2025…

Our NEW Primer on Thoracic aortic aneurysm is live today! By Berger, Dumfarth, Kreibich, Minatoya, Ziganshin & Czerny. Check it out here:

Program of the 46th International Aldosterone Conference is now online, see you July 10-11 at San Francisco, USA. aldosterone.org

Modulation of bone marrow haematopoietic stem cell activity as a therapeutic strategy after myocardial infarction. New paper by Jasmin Rettkowski, Timo Heidt, Nina Cabezas-Wallscheidt and colleagues www.nature.com/articles/s41... @achimlother.bsky.social

Neue Episode von Notfallreform - how to? mit @karagiannidis.bsky.social @uniklinik-fr.bsky.social open.spotify.com/episode/4OPd...

🌟 SAVE THE DATE: Talent Forum 2025! 🗓️ November 18–19 📍 @www.helmholtz-munich.de‬, Germany Showcase your research and network with global talents in #Epigenetics & Nucleic Acids Research! Apply by July 31 for a speaker spot —travel & accommodation covered. 🔜 Website coming soon!

Excellent review, thanks to the authors for putting this together www.nature.com/articles/s41...

Planning of the next ESAC meeting on aldosterone and MR is in full process. Mark your calendars and see you October 17-18 in Rome admire-network.org/2024/05/15/s...

A new benchmarking study assesses methods for comparing chromatin contact maps in 3D genome research. www.nature.com/articles/s41...

Insightful Editorial by Milton Packer cleaning up some myths on #Aldosterone and MR in heart failure treatment www.sciencedirect.com/science/arti...

Looking forward to an exciting Dutch-German molecular cardiology meeting www.klinikum.uni-heidelberg.de/the-22nd-dut...

Cardiac tamponade is a potentially life-threatening emergency, characterized by progressive intrapericardial accumulation of fluid (or pus, blood, clots or air) leading to increased intrapericardial pressure and compression of the heart. https://www.nature.c...

Single nucleus #RNAseq of human atria reveals a subpopulation of cardiac myocytes with high expression of #mineralocorticoid receptor target genes in atrial fibrillation. This confirms nicely what we found in experimental models, coming soon. www.biorxiv.org/content/10.1... #AF

Thousands “Stand Up for Science” Across the Country Including Nobel laureates, climate researchers, and parents of kids saved by groundbreaking drugs. www.motherjones.com/politics/202...

Crosstalk of non-myoytes in atrial myopathy and fibrillation physoc.onlinelibrary.wiley.com/doi/full/10.... #AF #cardiosky

please re-post! we are looking for a PhD candidate: www.uniklinik-freiburg.de/en/career/jo...

Great place to be!

We want you to help us #standupforscience2025 📣 We’re currently recruiting local leads and volunteers across all state capitals and other major cities across the US! If you’re interested in helping us organize, please fill out this form: airtable.com/app4h5wUssMG...

Our 🔥 brand-new PhD program IMPRS-EBM at the intersection of #Epigenetics, #Biophysics & #Metabolism is open for applications📢. Looking for a fully-funded #PhDposition at Max Planck? Here is your chance: www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...

Primary aldosteronism is characterized by dysregulated and relatively nonsuppressible aldosterone production that persists independent of its dominant regulators, renin and angiotensin II. Learn more: nej.md/3Wsvi5L #MedSky #CardioSky #OBGYN

Inotropes and mortality in patients with cardiogenic shock: more questions than answers academic.oup.com/ehjcvp/advan...

Reduction of hypokalemia with MR antagonists may decrease the burden of arrhythmia. Well-written Editorial: academic.oup.com/ehjcvp/advan...

A quick reminder: For every $1 of research funding, NIH generated $2.46 in economic activity. This includes funding jobs in all 50 states. This isn't a red/blue thing: 8.9 jobs per $1M in CA & 12 jobs per $1M in GA. #AcademicSky #PhDSky #MedSky #HealthSky #healthequity #SciComm bit.ly/40NkIc0

Honored to contribute to this important review on Epigenetic Regulation of Innate & Adaptive Immune Cells in Salt-Sensitive Hypertension, published in #CircRes Huge congrats to 1st author Ashley for leading this! Read it here: ahajrnls.org/40EUrMY #Hypertension #Epigenetics #ImmuneRegulation

Today's Paper of the Day is transplantation, bridging, and support technologies in pulmonary hypertension criticalcarereviews.com/latest-evide... Join us to read 1 paper per day and stay up-to-date as we cover the spectrum of critical care across 2025

intriguing study on the androgen receptor as "aging ticking clock" of natural aging, modulatable by removing/increasing androgens www.pnas.org/doi/10.1073/... #aging #myoblue #cardiosky

Can we predict survival after #CardiogenicShock? New research from researchers at Helsinki University and the Luxembourg Institute of Health show that a particular miRNA (miR-20b-5p) is associated with survival in cardiogenic shock! #CardioSky

A review worth reading on how to use diuretics in acute heart failure www.sciencedirect.com/science/arti... #CardioSky

Updated summary of current and novel biomarkers and their potential stages of release in cardiogenic shock onlinelibrary.wiley.com/doi/abs/10.1... @imit-freiburg.bsky.social