@leonidkruglyak.bsky.social
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reposted by
Alejandro Montenegro
13 days ago
What could possibly go wrong? "The AI Scientist, which creates research ideas, writes code, runs experiments, plots and analyses data, writes the entire scientific manuscript, and performs its own peer review"
www.nature.com/articles/s41...
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Towards end-to-end automation of AI research - Nature
An artificial intelligence system can produce research papers with minimal human involvement, even passing the first round of peer review for the workshop of a main machine learning conference.
https://www.nature.com/articles/s41586-026-10265-5
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reposted by
Alejandro Montenegro
about 2 months ago
But it does it quickly and congratulates you for asking
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reposted by
Amy Goldberg
3 months ago
New preprint! and my first single-author paper, so bear with me.
www.biorxiv.org/content/10.6...
Malaria population genetic studies have found some puzzling patterns: Ne estimates spanning orders of magnitude, genome-wide negative Tajima's D, and over a quarter of genes with ĻN/ĻS >1 1/n
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Rare variation in malaria parasites biases population-genetic inference
Understanding how pathogens evolve is fundamental to disease control and is a basic question in evolutionary biology, yet pathogens with complex life cycles violate assumptions of classic evolutionary...
https://www.biorxiv.org/content/10.64898/2026.01.09.698000v1
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reposted by
Nandita Garud
4 months ago
Grateful to share our paper on gene-specific selective sweeps in human gut microbiomes, now out in Nature! It has been a joy to work with
@rwolff.bsky.social
, whose insights and hard work made this possible.
www.nature.com/articles/s41...
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Gene-specific selective sweeps are pervasive across human gut microbiomes - Nature
Development and application of the integrated linkage disequilibrium score (iLDS) reveals both selective pressures impacting the human gut microbiome and the mechanisms by which gut bacteria adapt to ...
https://www.nature.com/articles/s41586-025-09798-y
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reposted by
Randall Munroe
4 months ago
Website Task Flowchart
xkcd.com/3175/
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reposted by
JPWeiland
5 months ago
Defaulting to surgical masks in health care settings in 2025 is one of the most dissapointing examples of reluctance to change despite overwhelming evidence. Even defaulting to KN95 style would significantly increase protection of the most vulnerable. Infuriating inertia in the HC industry.
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reposted by
Randall Munroe
6 months ago
Physics Paths
xkcd.com/3155/
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reposted by
Richard Sever
6 months ago
AI in biology: "I read about some new computational method...get excited because itās exactly what I need...I try the method...Most of the time things donāt work...I have seen this play out so many times my default assumption is nothing is going to work"
blog.genesmindsmachines.com/p/we-still-c...
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We still canāt predict much of anything in biology
Biology is hard. Yes, even for AI.
https://blog.genesmindsmachines.com/p/we-still-cant-predict-much-of-anything
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reposted by
Randall Munroe
6 months ago
Window Screen
xkcd.com/3151/
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reposted by
Richard Sever
6 months ago
Another record month for bioRxiv - and further evidence the pandemic spike+dip was just that and growth continues. Thanks to all involved and that includes š«µ
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reposted by
Randall Munroe
7 months ago
Biology Department
xkcd.com/3140/
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reposted by
Eric Topol
8 months ago
The are many anecdotes for
#ChatGPT
helping patients. But here's one with fallacious A.I. guidance that resulted in serious complications
www.acpjournals.org/doi/10.7326/...
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reposted by
Geoff Green
8 months ago
I've seen this on Bluesky and had to try it myself. The image below was the response to the prompt: "Show me a diagram of the US presidents since Herbert Hoover, with their names and years in office under their photos" Bravo, OpenAI, bravo.
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reposted by
Jesse Shapiro
9 months ago
One of the most memorable talks at the 2011 Joint Evolution Meeting in Ottawa was Rosie Redfield describing her attempts to replicate this work, chronicled in her epic blog (which deserves to be preserved in the internet history books):
rrresearch.fieldofscience.com/2010/12/arse...
add a skeleton here at some point
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reposted by
Richard Sever
9 months ago
Science finally retracts the Arsenic life paper
www.science.org/content/arti...
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Fifteen years later, Science retracts āarsenic lifeā paper despite study authorsā protests
Belated decision on widely disputed 2010 study pleases some critics but puzzles and dismays others
https://www.science.org/content/article/fifteen-years-later-science-retracts-arsenic-life-paper-despite-study-authors
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reposted by
Randall Munroe
9 months ago
Replication Crisis
xkcd.com/3117/
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reposted by
Ellis Rosen
9 months ago
My cartoon in this weeks
@newyorker.com
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reposted by
Anshul Kundaje
9 months ago
One thing that really bothers me with the new "virtual cell" terminology is that it is currently largely focused on a very narrow definition of models that can predict effects of trans perturbations (gene dosage, drugs etc) on gene expression. 1/
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Spotted in the wild today:
10 months ago
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reposted by
Lior Pachter
10 months ago
I wrote a review of a recent paper on false discovery and multiple testing correction.
liorpachter.wordpress.com/2025/06/16/r...
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Reply to: Reply to: False positives in the study of memory-related gene expression
In the Nature paper āSpatial transcriptomics reveal neuronāastrocyte synergy in long-term memoryā published on March 14th, 2024, authors Sun et al. claimed to identify cell-type specifiā¦
https://liorpachter.wordpress.com/2025/06/16/reply-to-reply-to-false-positives-in-the-study-of-memory-related-gene-expression/
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reposted by
Harmit Singh Malik
10 months ago
He resolved that he would not stop either, even though it was a huge sacrifice on his part. I believe this is what we owe our trainees: so long as they are invested in their work, we must be as well, even if it seems like the world is on fire around us, both literally and figuratively. 10/
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reposted by
Alejandro Montenegro
10 months ago
Also, always applies...
bsky.app/profile/aemo...
add a skeleton here at some point
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reposted by
Alejandro Montenegro
10 months ago
This, by Michael Lynch. I'd include AI techbros as well.
www.pnas.org/doi/10.1073/...
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reposted by
Randall Munroe
10 months ago
Archaea
xkcd.com/3095/
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reposted by
Amy Goldberg
about 1 year ago
Last callāhiring for my lab moving to UCLA!
add a skeleton here at some point
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reposted by
Sri Kosuri
11 months ago
Lux Capital &
@wolfejosh.bsky.social
are launching the Lux Science Helpline - a $100M commitment to support American scientists whose research is threatened by funding cuts, bureaucratic hurdles, and career roadblocks - that expands our Lux Labs program.
www.luxcapital.com/news/our-hel...
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Our Helpline for American Scientists
https://www.luxcapital.com/news/our-helpline-for-american-scientists
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reposted by
Stephen Turner
11 months ago
Not
@theonion.com
www.nytimes.com/2025/05/10/b...
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Elizabeth Holmesās Partner Has a New Blood-Testing Start-Up
https://www.nytimes.com/2025/05/10/business/elizabeth-holmes-partner-blood-testing-startup.html
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reposted by
Dr. David Miller š³ļøāš
11 months ago
š§Ŗ ICYMI: $25,000 bridge funding for terminated NSF grants. Major props for to the Spencer, Sloan, W. T. Grant, and Kapor Foundations for their swift action, even though we (and they) know this is a band-aid fix. Due May 30. Applications are brief: a 2-3 page memo of 6-month plans & other docs.
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Rapid Response Bridge Funding Program
In the face of recent abrupt shifts in federal funding for education research, including large-scale terminations of National Science Foundation (NSF) research grant awards, we have developed a rap...
https://www.spencer.org/grant_types/rapid-response-bridge-funding-program
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reposted by
Daniel Bolnick
11 months ago
Upset about federal funding cuts in the US? Want some ideas of what to do? I wrote a long-ish blog post about it here
ecoevoevoeco.blogspot.com
summarizing things I learned meeting with Senate & House aides this week with the
@aibsbiology.bsky.social
Congressional Visits Day event.
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Eco-Evo Evo-Eco
Academic musing by Hendry, Bolnick, Gotanda, and awesome guests. Opinions and statements expressed on this blog are the views of the author(s) and do not necessarily represent endorsement by the blog...
https://ecoevoevoeco.blogspot.com
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reposted by
Aaron D'Souza
11 months ago
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reposted by
Christopher Mims
12 months ago
We Now Know How AI āThinksāāand Itās Barely Thinking at All Maybe you've heard that AIs are "black boxes" But a growing body of research keeps arriving at the same conclusion: Today's AIs all work in surprisingly similar -- and simplistic -- ways 1/2
www.wsj.com/tech/ai/how-...
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We Now Know How AI āThinksāāand Itās Barely Thinking at All
The vast ābrainsā of artificial intelligence models can memorize endless lists of rules. Thatās useful, but not how humans solve problems.
https://www.wsj.com/tech/ai/how-ai-thinks-356969f8?st=JK4ruj&reflink=desktopwebshare_permalink
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reposted by
Derek Lowe
12 months ago
Thoughts on Demis Hassabis of Google DeepMind saying that AI could cure disease in general in ten years. Bonus index to my longer posts on AI/computational drug discovery over nearly 20 years!
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The End of Disease
https://www.science.org/content/blog-post/end-disease
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reposted by
Saccharomyces Genome Database
about 1 year ago
Apply by March31 for the 2025 Yeast Genetics and Genomics Course Jul22āAug12
www.yeastgenome.org/blog/apply-n...
This yearās instructors āGrant Brown, Soni Lacefield
@lacefieldlab.bsky.social
, and Greg Langā have designed a comprehensive course covering all things yeast from genetics to genomics!
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Apply Now for the 2025 Yeast Genetics and Genomics Course | SGD
The Saccharomyces Genome Database (SGD) provides comprehensive integrated biological information for the budding yeast Saccharomyces cerevisiae.
https://www.yeastgenome.org/blog/apply-now-for-the-2025-yeast-genetics-and-genomics-course
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reposted by
Richard Sever
about 1 year ago
Big news: we are setting up a new non-profit organization to run bioRxiv and medRxiv. It's called openRxiv [no it's not a new preprint server; it's dedicated organization to oversee the servers]
openrxiv.org
1/n
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Homepage - openRxiv
openRxiv is an independent non-profit, the new organizational home for bioRxiv and medRxiv, enabling researchers to instantly share groundbreaking findings with the global scientific community.
https://openrxiv.org/
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reposted by
Science Magazine
about 1 year ago
Breaking news: Thousands of researchers and their supporters, including recently fired federal workers, have gathered across the U.S. in response to layoffs and funding cuts ordered by the Trump administration.
scim.ag/41zlPv4
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Thousands gather across U.S. in Stand Up for Science events
Scientists rally across the country in response to layoffs and funding cuts ordered by the Trump administration
https://scim.ag/41zlPv4
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reposted by
about 1 year ago
Haru GUESS RIKISHI RECORD contest is on! Read rules below. Winner(s) get a banzuke from my copious collection. Go to this google sheet link to see open slots, you must reply here to choose a rikishi and record, only I can update the google sheet.
docs.google.com/spreadsheets...
Go! š¤
#harubasho2025
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reposted by
Carl T. Bergstrom
over 2 years ago
I fixed the headline. And I honestly don't understand how any journalist could write this story without mentioning the study author's own "extreme productivity".
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over 2 years ago
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reposted by
Eric Topol
over 2 years ago
From Mike Luckovitch
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