Amazing speed from the teams in Uganda and the DRC - impressive! Three genomes released so far - a few quick takes: 1️⃣ New genomes ~equidistant from 2007 and 2012 outbreaks. 2️⃣ Represents new spillover from reservoir. 3️⃣ Limited diversity, so too early to speculate on timing. Great work ⭐!

A new Lancet study just reported the primary mortality analysis from the RTS,S malaria vaccine implementation programme in Ghana, Kenya, and Malawi. The verdict after 46 months is 1 in 8 deaths averted in eligible children, a very important outcome. www.thelancet.com/journals/lan...

The Andes variant has been sequenced and publically shared. I leave it to virologists to dissect this first. virological.org/t/co... 1/2

What we choose to implement - and when - matters. Our work shows that proactive screening strategies can reduce transmission by ~40% vs reactive responses. A key lesson for preparedness. In PNAS Nexus: ow.ly/cLnu50YCrcn

Congratulations to Miguel Paredes, Ph.D. Epidemiology; M.D. Medicine, on being named to the 2026 Husky 100. His work on infectious disease spread, health equity and community-centered care reflects the very best of UW. #Husky100 https://bit.ly/4vyFDwL

Honored to be a part of the #Husky100 this year!

The CDC has paused testing for rabies and pox viruses, the family of viruses that includes smallpox and mpox — and by July will have no experts to advise states on clinical aspects of the diseases Gift link: www.nytimes.com/2026/04/01/h...

Excited to share our work w/ @justinlessler.bsky.social, Trevor Bedford & Amanda Perofsky: doi.org/10.1098/rspb.... We investigate when sequence datasets are informative about between-group transmission, and how this depends on the relative pace of mutation, between-group transmission and sampling.

Pediatricians contending with a sharp rise in vaccine hesitancy are trying to stay sensitive and supportive, even as they bear the brunt of parents’ mistrust and confusion. Gift link: www.nytimes.com/2026/03/11/h...

On the cover of The Lancet: Editorial — “Robert F Kennedy Jr: 1 year of failure” Read the latest issue: spkl.io/63327Aa31W

The full results of the STOMP trial are now published in @nejm.org Tecovirimat did not shorten time to symptom resolution or impact symptoms of clade II mpox. The findings are similar to PALM007 trial which found no beneficial effects of the drug for clade I mpox www.nejm.org/doi/full/10....

Brilliant plenary on STI trends at #CROI2026. DoxyPEP implementation in Seattle shows indirect reductions of syphilis rates in cisgender women who are not the target group for the intervention. Shared sexual networks with men who are the target intervention group?

I use this (overly simplified) schematic to explain to folks why maintaining high measles immunity is so hard. Even with 100% coverage, you get different outcomes depending on who and when you vaccinate. Consider a population with more kids than adults -- start with them all being susceptible.

COVID-19 vaccination status during pregnancy and preeclampsia risk: the pandemic-era cohort of the INTERCOVID consortium www.thelancet.com/journals/ecl...

Our Cutaneous Leishmaniasis cohort study in Ethiopia now out. Most patients received Sodium Stibogluconate but we show this has an extremely low cure rates at end of treatment. This data underpins our @globalhealthedctp3.bsky.social Multi-Arms-Multi-Stage trial to improve CL treatment.

Oh my GOD King County Public Health is just wilding out for Valentines Day (and a lovely one).

#Mpox: recombinant virus with genomic elements of clades Ib and IIb - Global www.who.int/emergencies/...

The real story about statin safety from >122,000 RCT participants with individual level data. They can cause new-onset diabetes and muscle pain/weakness, but other than that they are remarkably safe for 62 outcomes. Rare liver function test abnormalities thelancet.com/journals/lan...

“What we found is there’s no significant excess risk with statins for almost all the conditions listed in statin packaging as potential side effects… We now have really good evidence that although these things may well happen to people while they take statins, that statins are not the cause”

Oh boy. “The University of Florida and the Florida Department of Health in Alachua County are investigating potential measles exposure in two UF classes following two confirmed cases in the county. Health officials have begun contacting individuals who may have been exposed.” @aetiology.bsky.social

Mpox cohorts from NYC and Houston. Conclusion: Post-mpox sequelae frequently persisted 11 to 18 months after acute mpox, with limited body distribution or physical morbidity but with continued social and sexual effects. www.acpjournals.org/doi/10.7326/... #IDSky

The NIRSE-GAL study looking at real world impact of nirsevimab in infants in Spain. Of 12 492 eligible infants, 94·4% received immunization. RSV-related LRTI hospitalisations decreased by 85·9% in the 1st season and 55·3% in the 2nd. www.thelancet.com/journals/lan... #IDSky

20 out of 25 CIO director positions at CDC are vacant and filled by actings (or eliminated), just in the past year via CDC Data Project www.cdcdataproject.org/leadership-c...

Sharing this personal Op-Ed again given the abrupt and unjustified changes to the childhood vax schedule (www.statnews.com/2026/01/05/c...). The schedule protects not only the kiddos but their family and community too. The schedule should be guided by impartial evidence, not blatant political gain

Talking with my colleagues from around the world and thinking, as I do often these days, about this quote from my colleague @gregggonsalves.bsky.social, which articulated something that I think many of us know but is rarely said with this clarity. www.thenation.com/article/acti...

www.cdc.gov/mmwr/volumes... #IDSky #COVID #vaccines

In this analysis of clinical surveillance data, the median incubation period from exposure to rash was 13.6 days. Sexual transmission had a shorter median (10.3 days [CrI, 3.1 to 20.3 days]) than nonsexual transmission (13.5 days [CrI, 9.5 to 19.1 days]). www.acpjournals.org/doi/10.7326/...

A recombinant strain of mpox virus has been isolated from a patient in the UK containing fragments of clade I and clade II virus. Recombination occurs when two strains of virus infect a cell. These events tend to be rare but are well described in poxviruses. www.theguardian.com/world/2025/d...

In a new trial, one dose of an HPV vaccine was noninferior to two doses in preventing HPV type 16 or 18 infection. Full ESCUDDO trial results: nej.md/49OEzg1 Editorial: Evidence to Action — Single-Dose HPV Vaccination and Cervical HPV Infection nej.md/3XsH9Rx #MedSky #IDSky

Because of the hepatitis B birth dose and completion of the infant series of the vaccine, the U.S. has made significant progress in reducing chronic hepatitis B. Eliminating the birth dose would reverse this progress and put children's health at risk. Read more: www.aap.org/en/news-room...

“Since 1998, independent researchers have conducted more than 40 high-quality studies involving over 5.6 million people. The conclusion is clear and unambiguous: There’s no link between vaccines and autism." -Dr. Susan Kressly, AAP President on recent changes to the CDC's website

New paper reminds us yet again: HOMICIDE is the leading cause of death for pregnant women. Gun violence & partner violence are related. All-cause homicide & firearm homicide of pregnant women are higher, in states w/ higher calculated firearm ownership (1/x 🧵 jamanetwork.com/journals/jam...

Our lab's paper describing the North American H5N1 epizootic is out now in Nature! So thrilled to have this out, and congratulations to @lambod50.bsky.social for all the fantastic work on this: www.nature.com/articles/s41...

A fascinating new Lancet ID paper offers the strongest comparative evidence yet between infection-induced and vaccine-induced immunity against mpox. The study followed people for up to 2 years after infection with monkeypox virus or vaccination with MVA-BN. #IDsky www.thelancet.com/journals/lan...

Esto merece ser destacado mil veces ☝️

With millions at risk of losing SNAP in the coming days, a reminder: hunger doesn't happen in isolation. When food assistance disappears, families use rent money to eat. Then come evictions and homelessness. Housing, food, healthcare—it's all connected. Cut one thread and the whole thing unravels.

Three cases of clade Ib mpox not related to travel have been reported in LA. This raises concerns for probable local transmission. Vaccines are available and work to reduce disease severity or prevent infection. If you are eligible to get vaccinated do so. www.theguardian.com/us-news/2025...

Ebola virus in Kasai revives 50-year-old questions on viral latency www.thelancet.com/journals/lan...

“So far this year, over eight thousand cases of whooping cough have been recorded nationwide based on data from the CDC. Over one thousand of those cases are [in] Florida. “Well, the numbers are really alarming. It’s a warning to all of us,” said Dr. Ronald Lee Lindsay” @jackiantonovich.bsky.social

Excellent comprehensive review on #Syphilis just published in #JAMA. An old disease and a powerful mimic. Interpreting syphilis serologies and how to treat is probably one of the consult questions ID physicians get the most. #IDSky #MedSky jamanetwork.com/journals/jam...

Spike in Mpox cases in Chicago prompts public health warning… #IDSky wgntv.com/health/spike...

BREAKING: Friday night massacre underway at CDC. Doznes of "disease detectives," high-level scientists, entire Washington staff and editors of the MMWR (Morbidity and Mortality Weekly Report) have all been RIFed and received the following notice:

New study in @thelancet.com “After nearly 2 years of war and severe restrictions in humanitarian aid, tens of thousands of preschool-aged children in the Gaza Strip are suffering from preventable acute malnutrition and facing an increased risk of mortality” www.thelancet.com/journals/lan...

I have been trying to get this published as an op-ed, but I am going to post it here since I think it is timely in light of the "consent" extortion events. Deafening Quiet from the Scientific Establishment jeremymberg.github.io/jeremyberg.g... 1/14

The government shutdown interrupted CDC's disease updates, so Team Force of Infection spent our Saturday going to the websites of all 50 health departments to check on Covid-19, flu and RSV. caitlinrivers.substack.com/p/cdc-data-i...

It’s #MythBustingMonday. Today’s myth: “Multiple vaccines at once will overload a child’s immune system.” This idea is popular with anti-vaccine groups and also POTUS. But immunology, decades of research, and real-world data all say the same thing: it’s false. 🧵

We are excited to celebrate the success of 24 Hours to Save AIDS Research by announcing that the entire program is now available on YouTube. 1/ www.youtube.com/@HIVAIDSarou...

I was in FL visiting my family when the FL gov said they were canceling school vaccine reqs. I was frustrated & scared as the people I love depend on vaccines to stay safe. I wrote a more personal op-ed in the @sun-sentinel.com. A plea to keep my family safe. www.sun-sentinel.com/2025/09/16/f...

Tune in next week to hear about amazing HIV work that has saved countless lives but continues to be threatened. Help us #SaveAIDSResearch . I’ll be presenting with @reluctantlyjoe.bsky.social on mpox which affects many of the same communities as HIV and whose global funding is also under attack