Proteoform Mapping Calls for a Combined Effort From Bottom‐Up and Top‐Down Proteomics analyticalsciencejou... --- #proteomics #prot-paper

"Biomarker studies are the greatest reproducibility crisis in science" (M. Uhlén, 2025).

Thinking about putting this sign outside my facilities door . 🤔

To be honest, when I see conferences announced that have a majority of male invited speakers, I think the organisers are not trying hard enough. We have so many excellent #FemalesinMS and resources available there is really no excuse for it anymore #massspec #teammassspec #lipidomics #metabolomics

🎤 Get ready for more ANZMetSoc ECR Rapid-Fire! Hear 3min talks from 2 of 10 #ECR speakers: Emily Sunnucks (UT Sydney) on multi-omics & death 🧩Chrystal O’Connor (Lincoln Uni, NZ) on Indigenous-guided metabolomics 🌿 📅 Oct 29 🏆 Vote People’s Choice: tinyurl.com/ECR-Rapid-Fire #ANZMetSoc #Metabolomics

Correlation isn’t causation, as the mantra goes—but statistical noise in correlational data can reveal causal information. When X and Y are causally linked, their noise tends to be asymmetric & this can guide #CausalInference. Check out our 📃👇 doi.org/10.1111/nous... #philsky #philsci #StatsSky #HPS

AlphaDIA enables DIA transfer learning for feature-free proteomics - @mannlab.bsky.social @jalew188.bsky.social go.nature.com/4qmEQMM

I'll just leave this here: jocnf.pubpub.org/pub/qag76ip8...

Read more in @natcomms.nature.com by: @clairerich.bsky.social @lanamcclements.bsky.social @mattpadula.bsky.social @louisecole.bsky.social 🏫 @utsengage.bsky.social @centenaryinstitute.bsky.social @hmriaustralia.bsky.social @garvaninstitute.bsky.social www.nature.com/articles/s41...

Medical update: last infusion of six cycles of chemo. It's done. Oncologist is predicting more sometime, but cancer gone AFAIAC. PET scan in November. Feel tired but that's likely poor sleep. Have to ignore it cause I'm racing the MTB on Sunday....

Proteomics Webinar: DIA with FragPipe, DIA-NN, and Skyline Presenters: Eduard Sabidó and Brendan MacLean When: Tuesday, September 16, 8am (Pacific Time) Register Now ... skyline.ms/project/home... #massspec #proteomics

This is really interesting and worth five minutes of your time to read. www.smh.com.au/world/north-...

Pre-analytical drivers of bias in bead-enriched plasma proteomics | EMBO Molecular Medicine www.embopress.org/do... --- #proteomics #prot-paper

Perfectly encapsulates my feelings. www.afr.com/work-and-car...

UTS executive and council should read this. But I doubt they will. theconversation.com/universities...

Post-Translationally Modified Proteoforms as Biomarkers: From Discovery to Clinical Use academic.oup.com/cli... --- #proteomics #prot-paper

Steve Vai: I’m not a very disciplined person; it was a passion. Because passion is a much more powerful engine of creation than discipline.

This: www.theguardian.com/commentisfre...

MASSyPupX: A FREE, open-source platform for off-site processing of shotgun DDA and DIA proteomics data. ✅ Runs on USB, PC, or server ✅ Pre-installed tools & libraries ✅ Perfect for education, collaboration & resource-limited labs doi.org/10.1016/j.jp... #Proteomics #DDA #DIA #Bioinformatics #FOSS

Joe Rogan gets universities better than a lot of university administrators. Universities are supposed to be places where you tackle challenging ideas, and have your ideas challenged. If you take that away, you don't have a university anymore. No matter what you put on your letterhead.

When analysing peptides from in-gel digests by LC-MS/MS, has anyone noticed a 1+ ion of m/z 1342.93 after washing the column with 80% ACN? We are leaving the pump at 80% ACN at 1uL/min for 5 mins after our usual 0-40% ACN gradient. Doesn't correspond to any contaminants. #massspechelp

The fraud isn't the surprising bit. The fact that people were to scared to speak up. That's fucked. What kind of culture is that? Too bad it's common. www.smh.com.au/national/fol...

Want to see me rant about Bioinformatics related to Proteomics? Here's your chance. UTS-USYD Bioinformatics Symposium 2025 - Fri 18 July. Green Theatre (Building 7, Level 2, Room 025) at UTS. Register here: forms.gle/8CwyBjGAtBcF..., or the QR code in the flyer.

Best read for the weekend.

Aust Uni system is broke. Those in charge need to fix it or leave it to someone competent: theconversation.com/australias-u...

This rate of validation suggests that affinity reagents such as antibodies should be considered non-specific until proven otherwise: 357 validated antibodies out of 1,124 tested. .

Another review/opinion piece about why studying proteoforms is important, this time when dealing with Anti-Microbial Resistance. Written by my super-talented PhD student @breyerwoodland.bsky.social with Piklu Roy Chowdhury and Matt O'Rourke. doi.org/10.1016/j.ta...

(ACS Anal Chem) [ASAP] Rapid Multi-Omics for Bacterial Identification Using Flow Injection–Ion Mobility–Mass Spectrometry: Analytical ChemistryDOI: 10.1021/acs.analchem.5c00417 #MassSpecRSS #ACSAChem

The pulished version of the review is out: doi.org/10.1002/pmic.... Enjoy.

2024 Journal Impact Factors. Molecular & Cellular Proteomics: 5.5 Proteomics: 3.9 Proteomes: 3.6 Journal of Proteome Research: 3.6 Journal of Proteomics: 2.8 Equal to JPR. I'll take that. 🎉

I was worried about the cores finances, but now that we identified this protein in a sample, I think we will be okay right? www.uniprot.org/uniprotkb/A0...

The MIF @aimi-uts.bsky.social is proud to display the new #AcknowledgementGuidelines launched by @royalmicrosoc.bsky.social and @globalbioimaging.bsky.social – helping #ImagingScientists get #CreditWhereItsDue Download poster & join the campaign! globalbioimaging.org/documents/im...

(Friday, 3 weeks after chemo Rd 1). Oncologist: has your hair started falling out? Me: not that I've noticed.

My paper on consultant-vampires Nous sucking the lifeblood of universities goes into more detail about how these guys operate (co-written with @bestqualitycrab.bsky.social) www.tandfonline.com/doi/full/10....

My talk at Aus-Omics was recorded and I have finally sync'd it with the slides and shoved it on YouTube. youtu.be/mYjK5GCcqms

After not thinking about paralysis ticks since submitting my PhD in 2008, I am working on ticks again. Could probably still turn my thesis into an article after all this time. 🤔

2024 Citescore ranks are out. If I look at “Biochemistry”. MCP is 51 JPR is 118 Proteomes is 130 Journal of Proteomics is 143 Expert reviews in Proteomics is 176 Biochimica et Biophysica Acta - Proteins and Proteomics is 191 Proteomics is 204 As joint EiC with @bskytdp.bsky.social of Proteomes 😍

Bit of weird request. Mentoring a high school student doing a thought experiment on the Effectiveness of Natural vs. Chemical Antibacterial Agents. She needs to have consulted an international contact to demonstrate that she has sought a wide range of help and views. Anyone able to help?

Proteomics invited me to write a review on Multi-Omics. So we did. Just got accepted an the pre-print is here. Hopefully researchers find it useful. And yes, we did express our opinion on what we thought needs improving. And proteoforms got a mention. www.authorea.com/users/904760...

12/ Bioinformatics isn't just code. It's skepticism. It’s pattern recognition. It’s noticing when something feels off. Your instincts matter. Listen to them. Then verify with data.

I made a career out of this idea: www.smh.com.au/lifestyle/li...

It’s so nice that an important paper led by yasin - is out. www.nature.com/articles/s41.... This paper is a key milestone as it is the foundation for data science across data repositories through indexing and metadata harmonization of 1.6 million files (although much more now due to updates). 1/n

We’re pleased to have the opportunity to support our Editor-in-Chief, @mattpadula.bsky.social, and Editorial Board Member, Dr. Matthew O'Rourke, with travel grants to attend #AUSoMicS 2025 conference. Congratulations to both on their successful presentations! 🎉 #proteomics #proteomes #proteoforms