For decades, Alzheimer’s therapies assumed more acetylcholine = better memory. Our new paper in @alzdemjournals.bsky.social challenges this dogma, showing that the cholinergic system has opposite effects on memory depending on disease stage. 📌 alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

More than 20 years after their discovery, HFOs are reshaping how we understand epilepsy and increasingly, revealing important links to other brain disorders. In our new paper we reflect on how far the field has come and where it’s headed next. #HFOnews onlinelibrary.wiley.com/doi/10.1002/...

Thank you @cureepilepsy.bsky.social for this honor and for supporting my lab’s work on high frequency oscillations in epilepsy through a CURE Epilepsy award! #HFOnews Congratulations to all awardees!

Not just one biomarker, but many! Join our Epilepsy and Aging SIG for an exciting multimodal biomarker session. The session has it all from basic science to neuropsychology, EEG, and more! 🗓️ Monday, December 7, 2:00-3:30pm, Room GWCC B312, Level 3. @amepilepsysoc.bsky.social @yes-ilae.bsky.social

The @amepilepsysoc.bsky.social AES Annual Meeting is quickly approaching - have you marked your calendar for the exciting EEG BIOMARKER CHALLENGE? We will tackle whether EEG biomarkers are disease specific and WHY that matters! 🗓️ Sunday, December 7, 4:00-5:30pm Join us! #HFOnews

Not to be missed!! Mark your calendar! Great networking opportunity.

This scientific commentary refers to ‘High-frequency oscillations in epileptic and non-epileptic Alzheimer's disease patients and the differential effect of levetiracetam on the oscillations’, by Shandilya et al. @chrislisgaras.bsky.social Read at 👉 buff.ly/r3IcOEE

New paper out! We show that EEG biomarkers interact in opposite ways in Alzheimer’s disease (AD) vs. epilepsy. This could explain why epileptiform activity is inconsistently seen in AD—and highlights the need for wideband EEG to uncover these dynamics. #HFOnews www.sciencedirect.com/science/arti...

Greatly enjoyed writing this piece for @braincomms.bsky.social! 🔹 "High frequency opportunities for Alzheimer's disease" academic.oup.com/braincomms/a... This commentary calls for rethinking how we “listen to” and interpret abnormal electrical activity in Alzheimer’s disease and related dementias.

Off to beautiful Lisbon to speak the XVIII Workshop on Neurobiology of Epilepsies. Excited about this year’s topic on the resilient brain! Who’s coming?! #HFOnews 🧠 #ILAE @ilae-epilepsy.bsky.social

Exited to share our new work! We found scalp high frequency oscillations (HFOs) in adults with Down syndrome, before the clinical onset of Alzheimer’s dementia and late onset myoclonic epilepsy. HFOs may hold the key to earlier diagnosis #HFOnews alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Interested in how sleep is affected across the Alzheimer’s disease continuum in people with Down syndrome? 💤 Check our new publication with collaborators in Spain out in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. alz-journals.onlinelibrary.wiley.com/doi/10.1002/...

Interested in how preclinical studies can help understand EEG patterns? Take a look at our book chapter! With Marco de Curtis and Premysl Jiruska. link.springer.com/chapter/10.1... #HFOnews

#HFOnews! And first outcome publication of the Third International Workshop on High Frequency Oscillations in Epilepsy. 👇👇

Off to beautiful Verona for the Spring Hippocampal Research Conference! Who’s coming?! #HFOnews hippo.euroconferences.org/scientific-p...

Excited to be speaking about High Frequency Oscillations in Epilepsy and Sleep at the 2nd Annual Sleep Conference in NYC!

Happy World Down Syndrome day! We are advocating and are all inspired by individuals with Down syndrome. #WDSD2025

Join us next week for an @ilae-epilepsy.bsky.social webinar on High Frequency Oscillations! Dr. Sheybani @laurentsheybani.bsky.social and Dr. Jacobs will talk all about HFOs in epilepsy. #HFOnews Register here: docs.google.com/forms/d/1e-x...

A great one by @laurentsheybani.bsky.social - on the reading list!

Our #EEG Review was selected as @epilepsiajournal.bsky.social Editor’s Featured Article - give it a read here👇 onlinelibrary.wiley.com/doi/10.1111/...

Super excited to see our 2022 animal model study (onlinelibrary.wiley.com/doi/10.1111/...) showing HFOs in Alzheimer’s model systems replicated in humans! @braincomms.bsky.social The dream of every basic scientist 🤩 Our human study coming very soon :) #HFOnews academic.oup.com/braincomms/a...

Our review discussing the role of EEG in Epilepsy research is now out @epilepsiajournal.bsky.social @ilae-epilepsy.bsky.social Thanks to all of my co-authors! onlinelibrary.wiley.com/doi/10.1111/...

The time has come!

New paper out in Cell Reports! Led by @susieyufeng.bsky.social, we found that chronic epilepsy in mice drives distinct synchronization deficits in hippocampus and MEC, with early changes in HPC and late-onset changes in MEC that align with progressive memory impairment. www.cell.com/cell-reports...

🚨NIH-funded postdoc position! Looking for an electrophysiologist (ex/in-vivo) to work with us at Gladstone Institutes on mechanisms of oxidative stress, glucose metabolism, and network hyperexcitability in Alzheimer's disease 🧠 #neurojobs #postdocjob gladstone.wd5.myworkdayjobs.com/en-US/career...

SEEING THROUGH YOUR EYES 👁️: Excited to share our new paper (which is out now @nature.com !!) with Wenbo Tang, Antonio Fernandez-Ruiz✉️, and Azahara Oliva✉️: we discovered a novel sleep microstructure that promotes memory replay! #Neuroscience #hippocampus nature.com/articles/s41... 🧵 1/12👇

What a great weather in LA!!

On my way to sunny LA for the @amepilepsysoc.bsky.social Annual Meeting! Excited to be speaking about common EEG disturbances in Alzheimer’s Disease and Epilepsy models. Join our IW on AD and Epilepsy on Dec 8 at 3:15pm, Room 403A!

@serenadudette.bsky.social 💯 www.biorxiv.org/content/10.1...

#Bluesky meetup at AES? Who is in?!

Attending AES next week? Make sure you stop by at this social event! #AES #yesLAE

Here we are! 🦋 who’s around?!