New in @nature.com, @labnowakowski.bsky.social uses barcoded lineage tracing to reveal how different cell types in the human brain form, identifying a transition during development when some progenitors shift from making excitatory to inhibitory neurons. www.nature.com/articles/s41... #studyBRAIN 🧠🟦

Venkatesh Lab Fall Outing -- Apple Picking!

On the cover of the Journal of Neurosurgery, UCSF neurosurgeon Edward Chang, MD, PGY6 resident Anthony Lee, MD, PhD & team show that transposition approaches, especially with a pericranium sling, may result in more durable pain control for trigeminal neuralgia: thejns.org/view/journal...

Congratulations to @ucsfhealth.bsky.social neurosurgeon @herveyjumper.bsky.social on receiving the Guha Award from the AANS/CNS Section on Tumors & @neuroonc.bsky.social! 🎉 This award recognizes his lab’s research advances in cancer neuroscience and his dedication to mentoring. #2025CNS #CNSConnects

We’re excited to be in sunny L.A. for #2025CNS! Check out all the incredible work that our faculty, residents, and medical students are doing: neurosurgery.ucsf.edu/news/ucsf-ne... @herveyjumper.bsky.social @ucsfcancer.bsky.social @ucsfhealth.bsky.social #Neurosurgery

How to disconnect therapy-resistant tumor networks in glioblastoma? In our paper, online @Cancer Discovery, we built an anti-tumor microtube (TM) screening pipeline and found that Protein Kinase C activators disrupt TMs, silence Ca²⁺ “pacemakers” and boost radiotherapy. doi.org/10.1158/2159...

I’m thrilled to report on work I led with Dr. Shawn Hervey-Jumper and Dr. Todd Hollon which shows that we can forecast where glioblastoma will recur even at time of initial resection. It’s wonderful to see all the work I conducted during my research year @neurosurgucsf.bsky.social come together!

UCSF neurosurgeon @herveyjumper.bsky.social & his @umich.edu colleagues have developed an intraoperative tool called FastGlioma that uses AI to help neurosurgeons see in real-time where tumor cells have infiltrated brain tissue. 🧪 braintumorcenter.ucsf.edu/news/how-ai-... @ucsfcancer.bsky.social

See highlights of @ucsfradonc.bsky.social participation at the 2025 @astro-org.bsky.social conference starting tomorrow: cancer.ucsf.edu/news/2025/09... #ASTRO2025 #UCSF

Anti-seizure meds don’t work for 1 in 3 epilepsy patients. UCSF experts are closing the gap with surgery and breakthrough devices that can change lives. tiny.ucsf.edu/HzE2SS

Personalized conversations with a trained #AI chatbot can reduce belief in conspiracy theories, according to a 2024 Science study. The findings, which challenge the idea that such beliefs are impervious to change, point to a tool for combating misinformation. https://scim.ag/47uE1uz

Great talks and even more interesting and engaging discussion! Fantastic start to the think tank!

A breakthrough method for personalized deep brain stimulation (DBS) is improving Parkinson’s treatment, and could one day be applied to depression and other conditions. "Tailoring these treatments to the person’s neural signature is really the key,” Dr. Edward Chang says. https://ucsfh.org/45HdiIr

What an incredible month it has been completing my sub-I at @neurosurgucsf.bsky.social ! I learned so much, met so many incredible people, and I had a great time doing it. I am truly grateful to have had this opportunity. #Neurosurgery #Match2026

Peacocks have a secret hidden in their brightly colored tail feathers: tiny reflective structures that can amplify light into a laser beam. scim.ag/3UEM2oQ

We’re honored to be named among the top two neurosurgery programs nationwide and the Best in the West by @usnews.com! 🎉 It's a privilege caring for our patients and their families, and we thank our entire team for hard work and dedication. @ucsfhealth.bsky.social www.ucsfhealth.org/lp/us-news-2...

A new study led by @doriswang.bsky.social's lab developed a systematic way to quantify key aspects of gait in patients with #Parkinsons and used machine learning to identify personalized deep brain stimulation (DBS) settings to improve walking: www.ucsf.edu/news/2025/07... @ucsfhealth.bsky.social 🧠📈

Our latest research on the neural basis of speech-motor sequencing is now published in @nathumbehav.nature.com! Check out this high-level explainer video and read the full paper here: t.co/YKJlabr3yb

Electrocorticographic Detection of Speech Networks in Glioma-infiltrated Cortex https://www.biorxiv.org/content/10.1101/2025.07.04.663249v1

In @natcomms.nature.com, Takahide Nejo, PhD & the Okada lab worked with Saritha Krishna, PhD & @herveyjumper.bsky.social to show how the complex interaction between #glioblastoma and immune cells suppresses pro-inflammatory immune responses and drives tumor growth: www.nature.com/articles/s41... 🧪

Congratulations to @herveyjumper.bsky.social for being named this year's recipient of the Abhijit Guha Award! 🎉 This award recognizes his accomplishments as a neurosurgeon-scientist and his role as a mentor in the field of neuro-oncology. #SNO2025 @neuroonc.bsky.social @ucsfcancer.bsky.social

New paper with @herveyjumper.bsky.social and Vardhaan Ambati! It shows that causal (DCS+) language cortex in glioma patients has greater ECoG information encoding (higher entropy and linguistic decoding). DCS+ sites showed stronger oscillations and high gamma, enabling prediction of DCS sites.

NEW content online!

Harvey Fierstein, who has been a steady presence onstage and backstage over the course of 40 years, received a lifetime achievement Tony Award on Sunday night. Follow live updates. nyti.ms/445CFUN

Heading to the airport to catch a plane to Allegheny for my first neurosurgery Sub-I. There are not enough words to express the gratitude that I have for my research year in the Hervey-Jumper lab. Incredible group, work and mentorship. Feeling blessed.

Congratulations to @ucsfhealth.bsky.social neuro-oncologist Susan Chang, MD, on being named a Fellow of the @ascocancer.bsky.social for her dedication to volunteer service efforts within oncology that have benefitted the patients and the field! 🎉 #ASCO25 @ucsfcancer.bsky.social

Peers from @ucsanfrancisco.bsky.social celebrate with Dr. Eric Small @ucsfhealth.bsky.social at #ASCO25 as he prepares to assume his role as President of @ascocancer.bsky.social for the 2025-2026 year ascopost.com/issues/may-2...

Thrilled for this opportunity to present on the work I have been doing this past year in the lab of Dr. Hervey-Jumper! @neurosurgucsf.bsky.social

June 1st at 9:45 am CT Sanjeev Herr, BS, MS @sanjeevherr.bsky.social @ucsfhealth.bsky.social presents at #ASCO25 Clinical Science Symposium on Refining Local Therapies in Central Nervous System Oncology at Symposium during the @ascocancer.bsky.social annual meeting in Chicago. lnkd.in/gkF6dRDT

Tissue samples were from healthy cortex (e.g., insular tumor resection), allowing transcriptionally defined neuronal subclasses, including numbers of glutamatergic + GABAergic neurons. This link better enables aperiodic (1/f) slope from EEG/ECoG to be used as a surrogate for cortical excitability.

New paper with Shawn Hervey-Jumper's lab! As only PART of this project, it validates the relationship between aperiodic slope and cortical excitability using ECoG and single-nuc RNA sequencing in humans. Tissue samples with more excitatory neurons showed flatter aperiodic slope.

Aperiodic neural dynamics define a novel signature of glioma-induced excitation-inhibition dysregulation https://www.biorxiv.org/content/10.1101/2025.05.23.655626v1

Big News: We are proud to announce that @ucsanfrancisco.bsky.social's Chair of Neurosurgery, Edward Chang, MD, has been elected to the @nasonline.org — one of the highest honors given to American scientists! 🎉

Proud to be a part of this work!

New preprint + toolbox! BrainTRACE is a MATLAB tool for localizing intraOp ECoG electrodes. It was designed for brain tumor patients, but appropriate for all ECoG implants. github.com/dbrang/Brain... www.medrxiv.org/content/10.1...

Dr. Alexa Canady: The First Black Female Neurosurgeon Who Transformed Pediatric Medicine: In 1981, Dr. Alexa Irene Canady made history and then continued. That year, she became the first African American woman in the… The… #BlackHistory #WomenInMedicine #Neurosurgery #PediatricMedicine #Trailblazer

My experience at #AANS2025 this past weekend was a stark contrast to my experience last year. My first national neurosurgery conference last year and I did not know anyone, I was not presenting any of my work, and I had no clue what to do with my time.

This photo of a lone penguin atop an ice floe in Antarctica by Pete McBride, edited by Senior Photo Editor Charlie Borst, was recognized with a @commarts.com Award of Excellence. scim.ag/42kSBBW

After adding questions to a key survey last year, the U.S. National Science Foundation is reversing course. scim.ag/3XYCCXH

Congrats to our students who competed in the #UCSFGradSlam! Finalist Madeline Urbanek described how, in the Cadwell lab, she's mapping the connections between neurons and 2nd place winner Maggie Colton Cove summarized how, in the Okada lab, she's improving #CARTCellTherapy for brain tumors. 🧪

Congratulations to third-year UCSF medical student Abraham Dada on being named one of this year's @the-asci.bsky.social PSSF Fellows! 🎉 This award supports his research in the Hervey-Jumper lab studying how glioblastomas affect neuronal function: the-asci.org/controllers/... @ucsfcancer.bsky.social

Mapping the spatial architecture of glioblastoma from core to edge delineates niche-specific tumor cell states and intercellular interactions https://www.biorxiv.org/content/10.1101/2025.04.04.647096v1

Surgeon burnout is often discussed, but its impact on relationships is overlooked. As a neurosurgeon, wife, & mom I know firsthand that balancing work and family is tough. A recent study highlights the importance of relationship-focused burnout prevention journals.sagepub.com/doi/10.1177/...

We always teach an autistic child how to interact with a world that is not made for them. Maybe, we should also focus on teaching the world how to interact and embrace a child who is autistic. #autismawernessday #inclusion #neurodiversity #autism

Cory Booker as he breaks Strom Thurmond's speaking record: "I'm not here because of his speech. I'm here despite his speech. I'm here because as powerful as he was, the people are more powerful."

A big congratulations to @ucsanfrancisco.bsky.social neurosurgeon and scientist Shawn Hervey-Jumper, MD on being honored with the Mitchel S. Berger, MD Endowed Professorship! 🎉 @ucsfhealth.bsky.social @ucsfcancer.bsky.social #UCSFProud

An exceptional neurosurgeon. A brilliant scientist. An incredibly kind person. And without a doubt a better mentor/teacher than I could have ever hoped for. It was truly a privilege to see Dr. Shawn Hervey-Jumper receive the Mitchell S. Berger, MD endowed professorship yesterday. Congrats!

🧠✨ Today is Match Day, and we’re thrilled to welcome these 3 great minds: Grace Futch, MD, of Duke University Aden Mendoza, MD, of Duke University Molly Monsour, MD, of University of South Florida We can’t wait to see them scrub in, step up, and shape the future of neurosurgery. #Match2025

Please join us in welcoming the newest members of UCSF Neurosurgery! A big congratulations to Michael Baumgartner, MD, PhD, Jennifer Guidera, MD, PhD, and Maxwell Wang, MD, PhD 🎉⁠ #Match2025 #MatchDay #Neurosurgery @ucsanfrancisco.bsky.social @ucsfmedicine.bsky.social @pennmedicine.bsky.social

How does the #vasculature regulate #immune cell infiltration & function across different brain tumors? 🧠🧪 Excited to share our latest study in #Immunity where we uncover some interesting answers— led by the amazing @lbejarano.bsky.social 🤩👏🏻 🧵 @cp-immunity.bsky.social www.cell.com/immunity/ful...