A conundrum of a case from last year. Large brain lesion. No known hx of malignancy. No definite lesions on imaging elsewhere. Minimal hx provided in general. Frozen and paraffin sections: malignancy sharply demarcated from normal glial tissue. Does not look like a primary brain lesion. #PathSky

One of many skin lesions removed. Standard level of Australian solar elastosis. Invasive nests, vague peripheral palisading. #PathSky

Endobronchial lesion, reasonably chunky, somehow an “incidental” finding. #PathSky

Four leaf unlucky mitosis 🍀 #PathSky

Metastasis in motion. Tumour tracking towards the already pretty chockers lymph node.

The WHO #BlueBooks 6th ed. is coming out! Updates are based on current research and evidence - based. Each volume has an editor from a resource challenged setting. Increased harmonisation across volumes is pursued. Most entities include WSI’s . #GI6th & #Breast6th #Pathology

In Australia it’s Junior Doctor New Year. Traditional gifts given for this holiday include pens, coffee vouchers, and mandatory training modules.

The quilting section at Spotlight makes the 'are women suited to surgery?' discussion seem ludicrous. Quilters have been piecing fabric and driving needles through complex designs for centuries. Needle holders, right angle forceps, cutting blades- all here. #ILookLikeASurgeon #MedSky

Why on earth would I want to know about uterine cervicitis or cervicitis with that search phrase? Is this the new dumbing down of PubMed?

Putting the macro in macrophage

The only cute thing about this case on my desk. #PathSky

Great culture can save lives. Literally. Amazing letter in today’s @thetimes.com about Tom Stoppard

I don’t know if anyone else notices or cares, but when I see a presentation in which the speaker uses obviously generated-AI images to illustrate their slides, it makes me immediately less confident in whatever other content they’re presenting.

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WEHI stands behind the @aamri.bsky.social campaign to strengthen the sector and secure the future of medical research. Join the call to release the full MRFF and support our scientists to keep saving lives. Find out more: www.aamri.org.au/mrff #releasethefullmrff

@glaucomflecken.bsky.social never, ever misses the mark. #PathSky m.youtube.com/shorts/AHMrb...

Ok, ok. Here’s the twist - here’s the patient #pathsky #PathSky #dermpath

Did anyone pick the lack of solar elastosis and suspiciously high number of hair follicles?

#PathSky #dermpath Subcutaneous neck lump, present for 3+ years, slow growth. Macro: 40mm. Appears encapsulated. Unusually well excised!

#PathSky When the ovary ova-achieves and makes prostate.

I enjoyed this. And what an infectious laugh. ❤️ "Reporter left speechless after witnessing Japan's new $70 million Maglev train in action at 310 mph"

Unexpected item in the grossing area

PAS or Grocott not required here 😬 #PathSky

This - and subsequently reading Dexter Holland's Wikipedia entry - has absolutely made my day.

#PathSky Biopsy with gastritis on scope. Epithelial stripping, dense inflammatory infiltrate in the lamina propria, and thick subepithelial collagen band highlighted on trichrome -> collagenous gastritis. No significant neutrophil population and H. Pylori negative.

#PathSky Ulcerated skin lesion. Sheets of immature cells, mitoses +++, eosinophilic myelocytes (eosinophilic granular cytoplasm); MPO and CD43+ Haem team is very good and never fails to give the key history of AML.

Heading into my cytology era. #PathSky

T is for tumour #PathSky

Plenty studies showing that your postcode is a better predictor of your health outcomes than your genome.

Gratuitously posting this because I think kidney tumours are rewarding. Chromophobe RCC, plant-like cell walls and wrinkled nuclei. Very pretty staining for Hale’s colloidal iron. (Tumour was 133 mm!) #PathSky

Enough time to listen to All Too Well (10-Minute Version) 28,250,650,000 times.

PET-avid 🫁 lesion, hx of SCC elsewhere, biopsied. #PathSky

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Villi or crinkle-cut chips? #PathSky

Every time one of these lands in my inbox I think it's the cleverest and funniest thing Rick Morton has produced... until the next one.

Forbidden cookbook with completely unhinged cover art. #PathSky

It’s like a whole colon on one slide #pathsky #pathology #GIPathology #histology #histopathology

#PathSky Not only can you not ever trust invasive lobular breast cancer, you also DEFINITELY can’t trust micropapillary breast ca. Lymph node I initially thought was clear - with benefit of hindsight and AE1/AE3*, I revised this to ITCs. *ordered b/c I personally don’t trust micropap anything

If only all my exam revision could be done like this. #PathSky

Just... no. I cannot.

My latest @newscientist.com cartoon

Can confirm.

I can understand when my macro photos get classed as food, sort of, but a psammoma body?

Tall cell variant of papillary thyroid carcinoma. The cells are tall! (3x width) This had great nuclear features of PTC, along with psammoma bodies even in the lymphatics adjacent to involved nodes. #PathSky

One of the last things Papa Frank did was to make sure JD Vance knew the Pontiff thought him a heartless ghoul. RIP to a real one.

UNBELIEVABLE IN AUSTRALIA -HISTORIC Melbourne >30C/31C (AP) again: never happened anything like this in the second half of autumn. Scorching hot night, well above mid summer averages: Min 25.5 Sherger RAAF: April record of highest minimum That's absolutely mind blowing.

This is a classic sneaky dual diagnosis exam question!