Let's all do whatever we can to encourage smokers to quit & others to never start. 🚭🚭🚭

Mid-40’s male w/nasal obstruction Dx: allergic fungal sinusitis (polyps not shown) 📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells 📸 Charcot-Leyden crystals (arrows) 📸 occasionally fungal forms visible on H&E (arrow) 📸 fungus readily highlights w/GMS #PathSky

This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong? #pathsky #idpath Read more here in @IJSPjournal : journals.sagepub.com/doi/10.1177/...

This fungus looked exactly like Aspergillus but turned out to be Pseudallescheria (by microbiologic cultures). How should such cases be worded? Read more here in Int J Surg Pathol: journals.sagepub.com/doi/10.1177/... #pathsky #fungal #idsky #pathology #pulmpath

Case of the Month: A 2 year old boy presents to his pediatrician with pallor, fatigue and shortness of breath when playing. He lives with his parents and 4 siblings on a dairy farm. Access the rest of the clinical history and more via the link in comments. #Pathology #PathologyOutlines #PathSky

📸 frozen section, tumor capsule 📸 frozen section, epithelial cells (ducts) and myoepithelial cells 📸 frozen section, nests of myoepithelial cells in myxochondroid matrix Dx: pleomorphic adenoma #Pathsky

Frozen-section-Friday: Adult with 2 cm parotid mass sent for intraoperative consultation 📸: solitary, largely circumscribed, cut surface w internal heterogeneity 📸: touch prep - monotonous cells (myoeps) w/i basophilic matrix 📸: low mag nodule contour at frozen section …next #PathSky #ENTsky

Reduce variability and inconsistency in your approach to #amyloidosis diagnosis and laboratory workup! New #CAPguideline: brnw.ch/21wXMU6 #pathsky #pathology #CAPGuidelines

So many eosinophils in this case of tubulointerstitial nephritis secondary to recent antibiotic administration. Few tiny granulomas as well. Eos seen in EM as well. #renalpath #pathsky #nephsky

Thanksgiving reminder… ⚖️

Yes! The Davis/Thompson Foundation provides the infrastructure and storage for several veterinary Pathology groups; in return, they make their slides available at no charge.

We also have one of the largest repositories of veterinary gross pathology images freely available as well: davisthompsonfoundation.org/noahs-arkive/

Such a nice case! Thank you for sharing your expertise!

We see those! Mucicarmine highlights these beautifully.

#pathsky #pathology #pulmpath 3 thoracic pathologists discuss pathology of mesothelioma youtu.be/LVXlir8s8ik?...

KikoXP + WSI + videoconferencing + 3 subspecialty experts = new way to educate #pathsky youtu.be/LVXlir8s8ik?...

#ImageOfTheWeek ¦ The Fungal Superhighway 🧫 Cryptococcus neoformans (blue) moving through mouse nose tissue (pink). This image is the first time it’s been seen in this formation in the airways. 📸 Dr Vanessa Francis, MRC Centre for Medical Mycology #FungalInfection #Mycology #Science

Fungal hyphae are more tricky to diagnose by pathology alone than yeasts See detailed discussion here: journals.sagepub.com/doi/10.1177/... #pathsky #fungal #pathology

Hot off the press! New paper by Paula Toro et al showing the accuracy of fungal infection by pathology. 26-year experience! journals.sagepub.com/doi/10.1177/...

Look what I found with my prostate biopsies today #PathSky #floater

❌Flat Epithelial Atypia (FEA) low-grade cytologic atypia: monotonous, mildly enlarged nuclei "flat" = NO architectural disorder Apical snouts & luminal secretions TDLUs may be dilated/cystic #BreastPath #PathSky #Pathology 🔬 pathpresenter.net/public/displ... 🔬 dpa-dapa.com/public/displ...

Granular cell tumor found in the breast. Beautifully S100 positive (not pictured sadly). #PathSky

Something mundane from my work-life. #PathSky. This is a sentinel lymph-node (LN) biopsy from a patient with malignant melanoma: Already from low power you can see a "jump" in the texture of the LN. On higher power: atypical cells which produce pigment. --> Melanoma metastasis.

Fibrin thrombi at the periphery of an angiolipoma. It's the little things. #PathSky

Elephant in a lymph node #pathsky #pathart

A startling biopsy. Severe acute TMA in a pt with suspected scleroderma renal crisis. Massive vascular thrombosis, mucoid intimal edema, and early onion skin change associated with severe cortical necrosis. #renalpath #nephsky #pathsky

Happy people focus on what they have. Unhappy people focus on what they are missing. #Thoughtoftheday #Thursdaythought

#Chestrad - lymphangitic carcinomatosis 🫁 For more information: radiopaedia.org/articles/lym... #radiology #thoracicthursday @laurengroner.bsky.social @gbama11.medsky.social @pulmpeeps.bsky.social

Spooky season 👻 #Halloween

Cryptococcus can be diagnosed with high accuracy in surgical pathology or cytology specimens Case 5, Table 1 #pathology #pathsky Read the paper! journals.sagepub.com/doi/10.1177/...

#pathsky don't miss this amazing opportunity to learn from the best in the field, including the amazing Sean Williamson!

#pathsky this is my favorite pathology conference of the year with the best, most practical speakers. I guarantee you will learn new things you can use in your practice! Register here! www.ccfcme.org/pathology26

BTW, this diagnosis was a complete surprise to the treating docs. This patient had CVID and the Pulmonologists' and Radiologist leading ddx was granulomatous and lymphocytic interstitial lung disease (GLILD). They were VERY grateful that we got a definitive dx. Now, I wonder how many cases of GLILD

in CVID are actually unrecognized aspiration. I suppose we'll never know(???)

GLILD is a pathologic mish mash, as is any entity defined on the basis of clinical features! #pathsky

#pathsky Register now! www.clevelandclinicmeded.com/live/courses...

Important paper rebutting prior findings. "Thymectomy in adults with small or localized thymomas was not associated with increased 5-year mortality or cancer death." from @yalecancer.bsky.social in @iaslc.bsky.social JTO www.jto.org/article/S155...

a useful new paper on initial therapy of BRAF mut lung cancer. Retrospective data, but important question. urldefense.com/v3/__https:/... resulting from collaboration among 17 institutions including @mskcancercenter.bsky.social @danafarber.bsky.social @mdanderson.bsky.social

#pathsky sign up now!!

Proposals to Make Diagnostic Criteria truly Usable and Useful to Pathologists Worldwide jcp.bmj.com/content/earl... #Pathology @smlungpathguy.bsky.social @who.int @uscap.org @pathologists.bsky.social @americancancersoc.bsky.social @pathoverseas.bsky.social @ampath.bsky.social

Thymoma (typical low mag appearance) #pathology #pulmpath #pathsky

This is a neutrophil from an impression smear cytology of an infected skin lesion I did yesterday. Guess what body part the sample came from? #pathsky #vetmedsky

#idboardreview 25 M from Madagascar 🇲🇬 swam all life in freshwater lakes presents w/ 1wk fever, pleuritic chest pain, hemoptysis, hypoxia. CT chest shown s/p lobectomy +tissue necrosis. CT pelvis: bladder wall calcification. Diagnosis? #medEd #idmedEd #IDsky

Learn GU, breast, GYN, GI and thoracic pathology from the best teachers. Sign up now! www.clevelandclinicmeded.com/live/courses...

#idboardreview 30 M Paraguay 🇵🇾 living w/ HIV CD4 50 VL 100k presents w/ seizure, no travel/no animal contact. Oriented to self, dysarthria, csf (wbc 15 100% lymph, protein80, gluc35). Dx? #medEd #idmedEd #idtwitter

youtu.be/5ZugUzLup5g?... #pathsky

#pathsky #pathology #pulmpath youtu.be/Iq7r-hRJcZo?...

Lymphangioleiomyomatosis: 1. Yet another misnomer in #pulmpath 2. PEComatous proliferations in walls of lung cysts 3. ALWAYS consider in women with bilateral lung cysts, recurrent pneumothoraces, tuberous sclerosis or renal angiomyolipoma 4. VERY IMPORTANT for boards #pathsky