OP squeezing through a pore of Kohn youtube.com/shorts/V6sJs...

Final version of this article is now posted! Granular/oncocytic lung carcinomas: what these are, and how they can cause diagnostic problems. sciencedirect.com/science/arti...

What do you think of when you see a granuloma in a vessel wall in the lung? Watch this 51 second YouTube short to learn a quick tip! Link: youtube.com/shorts/82RE5Q9dFfw

Interested in #LungPath? Don’t miss HSCP’s Annual Spring Symposium in Houston next month! 😆🔬🫁 Hear from incredible speakers, including @smlungpathguy.bsky.social, and connect with leaders in the field! #pathology #MDACCPath

40’s FM parotid mass Dx: mucoepidermoid ca 📸 macro: ill defined borders, largely solid, focal cystic (arrowhead). Parotid node (solid arrow) and skel.muscle (open arrow) 📸 touch prep: clusters polygonal cells w/dense cytoplasm 📸 scan mag appearance #PathSky #ENTSky #Radsky #Otosky #PathTwitter

60’s male, parotid mass Dx: Warthin tumor 📸macro: cystic-solid mass, note layering of cystic contents for gross-micro correlate [arrow] 📸low mag overview [arrow for gross-micro reference] 📸papillary projections w/lymphoid stroma 📸bilayered oncocytic epithelium #PathSky #Otosky #PathTwitter #ENTsky

50s yom maxillary sinus Dx: sinonasal papilloma, inverted-type 📸macro: partially translucent mass w/cerebriform opaque infoldings 📸low: downward growth of epi 📸 mucous cells (arrow) & microabscess formation 📸 thick squamous epi w/transmigrating neutrophils #Pathsky #Otosky #ENTsky #macromicropath

This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong? #pathsky #idpath Read more here in @IJSPjournal : journals.sagepub.com/doi/10.1177/...

This fungus looked exactly like Aspergillus but turned out to be Pseudallescheria (by microbiologic cultures). How should such cases be worded? Read more here in Int J Surg Pathol: journals.sagepub.com/doi/10.1177/... #pathsky #fungal #idsky #pathology #pulmpath

Beautiful!

To open 2026, here is one of the rarest findings in a lung biopsy: fruiting body of Rhizopus (confirmed by PCR) #pathology #pulmpath #pathbugs #pathsky To read how these fruiting bodies differ from those of Aspergillus, click here: journals.sagepub.com/doi/10.1177/...

Image of the Week! Contributed by: Maria Tretiakova, M.D., Ph.D Textbook topic: Kidney tumor Diagnosis: TFEB rearranged RCC Textbook topic link: www.pathologyoutlines.com/topic/kidney... #Pathology #PathologyOutlines #PathSky

My first post on this platform. Hope I am not messing this up, but here it goes... This is for neuroendocrino-philes here: Excited to share the latest paper from our group on lung carcinoids. onlinelibrary.wiley.com/doi/10.1111/... pubmed.ncbi.nlm.nih.gov/41489019/

The best thing you learn from the worst time of your life is that you get to see the true colors of everyone. #Thoughtoftheday #Wednesdaythought

The countdown begins! Only 15 days to go!! I hear some folks are not only attending but staying for the full week! So much to do, great hotel, and great weather! #pathsky Register here: www.clevelandclinicmeded.com/live/courses...

To open 2026, here is one of the rarest findings in a lung biopsy: fruiting body of Rhizopus (confirmed by PCR) #pathology #pulmpath #pathbugs #pathsky To read how these fruiting bodies differ from those of Aspergillus, click here: journals.sagepub.com/doi/10.1177/...

3 weeks to go! There's still time to sign up!! clevelandcliniclabs.com/register-now... #pathsky

Paracoccidioides venezuelensis dimorphism

Direct examination with clorazol Black 400X of bronchial sample: hyaline hyphae suggestive of Aspergilosis

“Worst drug ever. Makes you smell bad, kills you, and doesn’t get you high.”

#pathsky journals.sagepub.com/doi/10.1177/...

Let's all do whatever we can to encourage smokers to quit & others to never start. 🚭🚭🚭

Mid-40’s male w/nasal obstruction Dx: allergic fungal sinusitis (polyps not shown) 📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells 📸 Charcot-Leyden crystals (arrows) 📸 occasionally fungal forms visible on H&E (arrow) 📸 fungus readily highlights w/GMS #PathSky

This fungal yeast was called Histoplasma on biopsy. This diagnosis was later confirmed by cultures. How often does this approach go wrong? #pathsky #idpath Read more here in @IJSPjournal : journals.sagepub.com/doi/10.1177/...

This fungus looked exactly like Aspergillus but turned out to be Pseudallescheria (by microbiologic cultures). How should such cases be worded? Read more here in Int J Surg Pathol: journals.sagepub.com/doi/10.1177/... #pathsky #fungal #idsky #pathology #pulmpath

Case of the Month: A 2 year old boy presents to his pediatrician with pallor, fatigue and shortness of breath when playing. He lives with his parents and 4 siblings on a dairy farm. Access the rest of the clinical history and more via the link in comments. #Pathology #PathologyOutlines #PathSky

📸 frozen section, tumor capsule 📸 frozen section, epithelial cells (ducts) and myoepithelial cells 📸 frozen section, nests of myoepithelial cells in myxochondroid matrix Dx: pleomorphic adenoma #Pathsky

Frozen-section-Friday: Adult with 2 cm parotid mass sent for intraoperative consultation 📸: solitary, largely circumscribed, cut surface w internal heterogeneity 📸: touch prep - monotonous cells (myoeps) w/i basophilic matrix 📸: low mag nodule contour at frozen section …next #PathSky #ENTsky

Reduce variability and inconsistency in your approach to #amyloidosis diagnosis and laboratory workup! New #CAPguideline: brnw.ch/21wXMU6 #pathsky #pathology #CAPGuidelines

So many eosinophils in this case of tubulointerstitial nephritis secondary to recent antibiotic administration. Few tiny granulomas as well. Eos seen in EM as well. #renalpath #pathsky #nephsky

Thanksgiving reminder… ⚖️

Yes! The Davis/Thompson Foundation provides the infrastructure and storage for several veterinary Pathology groups; in return, they make their slides available at no charge.

We also have one of the largest repositories of veterinary gross pathology images freely available as well: davisthompsonfoundation.org/noahs-arkive/

Such a nice case! Thank you for sharing your expertise!

We see those! Mucicarmine highlights these beautifully.

#pathsky #pathology #pulmpath 3 thoracic pathologists discuss pathology of mesothelioma youtu.be/LVXlir8s8ik?...

KikoXP + WSI + videoconferencing + 3 subspecialty experts = new way to educate #pathsky youtu.be/LVXlir8s8ik?...

#ImageOfTheWeek ¦ The Fungal Superhighway 🧫 Cryptococcus neoformans (blue) moving through mouse nose tissue (pink). This image is the first time it’s been seen in this formation in the airways. 📸 Dr Vanessa Francis, MRC Centre for Medical Mycology #FungalInfection #Mycology #Science

Fungal hyphae are more tricky to diagnose by pathology alone than yeasts See detailed discussion here: journals.sagepub.com/doi/10.1177/... #pathsky #fungal #pathology

Hot off the press! New paper by Paula Toro et al showing the accuracy of fungal infection by pathology. 26-year experience! journals.sagepub.com/doi/10.1177/...

Look what I found with my prostate biopsies today #PathSky #floater

❌Flat Epithelial Atypia (FEA) low-grade cytologic atypia: monotonous, mildly enlarged nuclei "flat" = NO architectural disorder Apical snouts & luminal secretions TDLUs may be dilated/cystic #BreastPath #PathSky #Pathology 🔬 pathpresenter.net/public/displ... 🔬 dpa-dapa.com/public/displ...

Granular cell tumor found in the breast. Beautifully S100 positive (not pictured sadly). #PathSky

Something mundane from my work-life. #PathSky. This is a sentinel lymph-node (LN) biopsy from a patient with malignant melanoma: Already from low power you can see a "jump" in the texture of the LN. On higher power: atypical cells which produce pigment. --> Melanoma metastasis.

Fibrin thrombi at the periphery of an angiolipoma. It's the little things. #PathSky

Elephant in a lymph node #pathsky #pathart

A startling biopsy. Severe acute TMA in a pt with suspected scleroderma renal crisis. Massive vascular thrombosis, mucoid intimal edema, and early onion skin change associated with severe cortical necrosis. #renalpath #nephsky #pathsky

Happy people focus on what they have. Unhappy people focus on what they are missing. #Thoughtoftheday #Thursdaythought

#Chestrad - lymphangitic carcinomatosis 🫁 For more information: radiopaedia.org/articles/lym... #radiology #thoracicthursday @laurengroner.bsky.social @gbama11.medsky.social @pulmpeeps.bsky.social