I joined the Sohal lab with one major hypothesis: psychedelic drugs can be powerful psychiatric treatments, depending on underlying neurobiology. Indeed, psilocybin restored cognitive flexibility in one circuit model of dysfunction, but not another! Then, we had to find out how! 🧠🍄🧪

Read about four ways UC San Francisco researchers are pioneering novel treatments in depression, Parkinson’s, and addiction. https://www.ucsf.edu/news/2026/03/431626/magic-mushrooms-lsd-peek-inside-medicines-psychedelic-promise

The UCSF/VA Translational Psychedelic Research Program seeks postdoctoral fellows to advance rigorous psychedelic-therapy trials investigating neural, cognitive, & behavioral mechanisms in depression, neurodegenerative & eating disorders, chronic pain, and Veterans. 2 years guaranteed, 3rd possible.

🚨Publication alert! 🚨 Why does stress drive psychopathology & transdiagnostic disease? We present the Allostatic Triage Model of Psychopathology (ATP Model), which explains stress-induced transdiagnostic disease pathogenesis through a bioenergetic lens. www.sciencedirect.com/science/arti...

Out: vaccines Hot: virus and bacterial micro dosing

Found this guy on my front porch. His beady eye freaks me out.

New CDC guidelines say correlation is causation.

TrPR recently came together for a half-day retreat. We began with a living timeline: everyone arranged themselves by order of joining, from newest to oldest. I jogged along the line, camera in hand, past the smiling faces on the sunlit terrace of the Pritzker Building—and ended where it all began

Where else can you get a cup of joe for a $1? Serving those who served! #sfva

Just spoke with CNN about Casey Means, psilocybin, and the future of psychedelic therapy. These compounds hold real promise—but we need science, structure, and safeguards. urldefense.com/v3/__https:/... #psychedelics #psilocybin #mentalhealth #clinicaltrials

Due to the whites of the eye, humans have a uniquely communicative gaze. Other primates have dark eyes, hiding their gaze from conspecifics. We cooperate, they compete. Common knowledge – right? Yes, but it’s incorrect, as we argue in our new paper 🧵🧪1/11 onlinelibrary.wiley.com/doi/10.1111/...

Just spoke with CNN about Casey Means, psilocybin, and the future of psychedelic therapy. These compounds hold real promise—but we need science, structure, and safeguards. urldefense.com/v3/__https:/... #psychedelics #psilocybin #mentalhealth #clinicaltrials

Last year, @jacobsaday.bsky.social and @trpr-ucsf.bsky.social asked: "Psychedelic assisted psychotherapy: where is the psychotherapy research?" link.springer.com/article/10.1... How soon can we say "here it comes"?

New research on physical touch in psychedelic therapy reveals fascinating tensions in the field - a thread #psychedelicscience

Influencing the youth

So glad to see this work coming from the @trpr-ucsf.bsky.social lab. This paper highlights the lack of diversity and demographic reporting in clinical trials.

Are these psilocybe? Mainstreaming!

Just published: 7 years of routine outcomes monitoring from UC Berkeley Psych Clinic 📊 Clients from minoritized groups started with more severe symptoms, but improved just as much as majority clients. Culturally sensitive therapy works! rdcu.be/ei49c

I am enduring with integrity

I am a professor at Columbia University. All of the student NIH training grants have been canceled and now there are reports that ALL funding will be frozen. Why are Universities not banding together and speaking out publicly and forcibly about governmental attacks on biomedical research?

Noticeably silent amid the upheaval at HHS? Big pharma. Every new drug has NIH somewhere in its DNA--and NIH funding supports the training of their workforce. Now they're finding out FDA isn't safe, either. Wrote about how keeping quiet isn't working My latest @opinion.bloomberg.com (gift link):

“She was required, under a new return-to-office policy, to conduct virtual psychotherapy with her patients from one of 13 cubicles in a large open office space, the kind of setup used for call centers.” www.nytimes.com/2025/03/22/u... via @NYTimes

HEY DORKS IN AMERICA!! If we don’t get into the streets and fight this, there will be no science left here. We don’t have time for luke warm, diplomatic takes and accusations of “taking this clown too seriously.” Put your big girl pants on and LFG.

Women Resisters!

lol I did this yesterdays and my local barista loved it ❤️

@msmacb.bsky.social on NYT's cringey smear of @psymposia.bsky.social: “When vague accusations of ‘DEI’ and ‘wokeness’ are already being used to gut government programs, it might not be a bad time to blame the FDA’s decision on ‘a small band of anticapitalist activists.’” slate.com/technology/2...

An NYT Story Blamed Leftists for Obstructing Psychedelic Therapy. The Truth Is Much More Infuriating. slate.com/technology/2...

Gotta love Janet! ❤️ She is a badass, isn’t she?! 🤚 Pass. It. On. ✨

Billionaire’s breakfast? None of the dystopian novels prepared me for an egg based economy

Musk is slandering the Federal career workforce, lying & saying they don't exist. 30% of the Federal workforce are American Veterans. 15% are disabled Veterans. 80% of the Federal workforce lives outside of the DC area. These are your neighbors, working for you. ourpublicservice.org/fed-figures/...

How do we bookmark bleets?

We’ve launched a new clinical trial exploring the efficacy of psilocybin therapy for anorexia nervosa in young adults (age 18 to 25)! Learn more at tiny.ucsf.edu/HTkr9L or take our pre-screen survey to see if you’re a good fit tiny.ucsf.edu/gmvCA3.

Sopranos bustout episode

#USpol DOGE can’t find any Fraud

The DOGE firings have nothing to do with “efficiency” or “cutting waste.” They’re a direct push to weaken federal agencies perceived as liberal. This was evident from the start, and now the data confirms it: targeted agencies overwhelmingly those seen as more left-leaning. 🧵⬇️

Look how efficient DOGE is!!!

Employees should use ai to an answer this question as surely they will use ai to review the answers.

This is why…current OMB Dir & Project 2025 Founder Russell Vought said this:

Check GPT generated this for me what do you think?.

Ok scientists & those who love science 🧪: here is another exhortation. Call Congress TODAY about the freeze on NIH Council Meetings and Study Sections. Emphasize that this means NO new grants are being funded & labs will soon start to shut down and fire employees. Phone numbers are at: 5calls.org

““This crisis — and I’m not exaggerating by calling it a crisis — has already consumed one funding cycle…But if this block to publishing in the register continues on much longer, it’s going to swallow two funding cycles, and that will put many labs out of business.” @labonnelab.bsky.social

"The very fact that I am having to publish this anonymously in a country that has the right to free speech written into our Constitution is an indictment of what is happening." www.bmj.com/content/388/...

Correct.

Get in Dorks, we are going protesting. STAND UP FOR SCIENCE. MARCH 7th 12-4pm. DC AND YOUR STATE CAPITALS. More information to come.