An interesting new preprint about self-compassion in psychedelics. Seeing growing research here with Gabrielle Agin-Liebes leading the way. www.researchgate.net/publication/... #psychedelicscience

🍄 Our new living systematic review and meta-analysis on psilocybin for depression is out. Here's what we found and the open science infrastructure we built to support it 🧪🧵 www.medrxiv.org/content/10.1...

Love this new review on psychedelics & emotions from colleagues! One theme—how we measure positive emotions— resonates with our paper on why distinct positive emotions need more focus in psychedelic science, given their potential role in therapeutic benefits: www.tandfonline.com/doi/10.1080/...

New study showing that psilocybin can be given to patients on ventilators, dialysis, and with advanced heart failure. Zero serious adverse events occurred further demonstrating that psilocybin can be safe with appropriate medical monitoring. #psychedelicscience

Applications close in 10 days - don't miss out on this great opportunity! ALSO!!! another research role in our lab coming soon – please subscribe for announcement if you’re not eligible for the current one: www.monash.edu/medicine/scs...

New analysis reveals a huge disconnect in MDMA therapy pricing: Lykos wants $36,000 for the drug alone, but researchers calculate it it needs to be around $10,500 to be cost saving. This could be the difference between a niche drug for a few vs a breakthrough therapy accessible to millions.

Odds of winning NIH grants plummet as new funding policy and spending delays bite | Science | AAAS share.google/viASDaYC4l6n...

Interesting... MDMA-assisted therapy as a treatment for major depressive disorder: proof of principle study www.cambridge.org/core/journal...

The newest episode of my Research Matters Podcast it out, this time with Louis Castonguay talking about all he's learned forming and managing multiple practice research networks. He was a very entertaining and knowledgeable guest. I learned a ton. jasonluoma.com/podcast/loui... #researchmatterspod

Psychedelics use continues to increase in the USA among people over 25 years old (not for younger cohorts, with a drop in later adolescents. [from 2024 National Survey on Drug Use and Health]

I’m looking for a postdoc to join me at UCSD, ideally a clinical psychologist PhD who can deliver mindfulness interventions as well as write papers and do analyses. I have one of the world’s largest psychophysiology datasets of opioid misuse, OUD, & chronic pain. Competitive salary. DM or email.

new paper just dropped in Brain and Behaviour, with @bman1285.bsky.social and colleagues: doi.org/10.1002/brb3...

New report commissioned by Harvard reveals psychedelic training programs are in crisis. After MDMA's FDA rejection, it seems like the rush of new psychedelic trainees that was anticipated has stalled.

Many people report pain relief from psychedelics in surveys, but rigorous animal testing shows ZERO analgesic effects. This new preprint may reveal something crucial about how psychedelics might actually help with pain. www.biorxiv.org/content/10.1... #psychedelicscience

Good example of how route of administration makes a huge difference in dosing. In this study of sublingual dosing, 12mg of 5-MeO-DMT had relatively small subjective effects, but when that much is inhaled or insufflated, it has profound psychedelic effects: rdcu.be/ew4rJ

Interesting article here. suggests that lykos might not need to run another phase three study, and that mdma approval could happen within twelve months. open.substack.com/pub/ecstatic... #psychedelicscience

NIH being flooded with applications and then this. We're gonna see more of this. Seems like some major adaptation for journals will need to happen. search.app/t6t6T

Big news for psychedelic research in Europe: The new €4.3M INTEGRATE project will train 16 PhDs across Europe. Funded by Marie Skłodowska-Curie Actions, it marks a major step forward. PAREA is proud to support by hosting secondments. More here: parea.eu/parea-news/i...

Another study on psychedelics with military veterans going to a retreat. We've had several of these now showing pre-to-post improvements in mental health. Good to see this but we really need to have: 1. controlled trials and 2. a greater focus on *how* psychedelics work. #psychedelicscience

Doing psychedelic research with Spanish-speaking populations & interested in avoidance/acceptance? There is now a culturally decentered Spanish APEQ version designed to work equally well across the Spanish-speaking world: www.sciencedirect.com/science/arti...

Oh boy: People are using AI to ‘sit’ with them while they trip on psychedelics share.google/6dN63x94HUmd...

Enjoyed this recent paper about considering psychedelics as tools to accelerate psychotherapy vs interventions in and of themselves. doi.org/10.1177/2050... #psychedelicscience

New study on vaporized DMT. Largest study of it's kind to date I believe: doi.org/10.1016/j.eu... #psychedelicscience

Interesting new paper examining ketamine assisted therapy with and without music. 10.1192/bjp.2025.102 #psychedelicscience

Special section on CBT and psychedelics just published. Can't wait to see the data resulting from these studies. Introduction: Charting a New Frontier: Integrating Cognitive Behavioral Therapy Approaches with 3,4-methylenedioxymethamphetamine: www.sciencedirect.com/science/arti...

New poster just shared showing that mystical experience predicts heavy drinking days in a trial of psilocybin-assisted therapy for alcohol use disorder. Gotta assume they are preparing this one for publication. isctm.org/public_acces... #psychedelicscience

New research in #psychedelicscience documents how meeting "entities" during psychedelic experiences can profoundly impact spiritual wellbeing - both in helpful and harmful ways. This phenomenon deserves more research attention!

Hosting online workshop tomorrow on ethics and risks in psychedelic integration therapy. www.portlandpsychotherapytraining.com/5-16-2025-et...

New data shows that psilocybin use is skyrocketing in the USA. Here's a quote from an article that summarized data from multiple databases: "From 2019, past-year psilocybin use increased 44% among young adults (aged 18 to 29 years) and 188% among older adults (aged ≥30 years)" #psychedelicscience

Early meta analysis of a sort on the association between therapeutic alliance and psychedelic-assisted therapy. Almost certainly an inflated effect size (this showed r = .4 vs psychotherapy generally is closer to r = .2, but interesting nonetheless.

Participate in the Global Psychedelic Survey 2025 (GPS 2025), a large global study on psychedelic use. Sponsored by Uni of Michigan, closes May 16! Win 1 of 15 $100 Amazon gift cards. Take part: bit.ly/GPS2025-survey #GPS2025 #PsychedelicResearch #GlobalSurvey

Dispatch from Breaking Convention 2025: Part 2 Inside: - Ethical dilemmas of giving psychedelics to young people - Critical role of therapist selection, - Female biology X psychedelics - Pros/cons of non-hallucinogenic psychoplastogens and more... psychedelicalpha.com/news/dispatc...

Awesome to see this study out! Was wondering if this was gonna be analyzed. We are about to analyze our self compassion data with mdma-at and social anxiety and will see if this replicates.

New research on physical touch in psychedelic therapy reveals fascinating tensions in the field - a thread #psychedelicscience

New research suggests 5-MeO-DMT can induce a paradoxical state where people experience BOTH "everything" and "nothing" simultaneously—complete absence of self yet with preserved awareness. This could be valuable in understanding the foundations of consciousness itself. #psychedelicscience - a thread

I don't know who made this #psychedelics paper one but I love it so much I framed a copy for my office

Good interview about placebos in psychedelic trials.

Interesting new study on HPPD in psychedelics. A prospective study found that younger age, female gender, history of psychiatric diagnosis, and high "absorption" trait are significant predictors of HPPD-type effects. #psychedelicscience

Just published in the Journal of Psychoactive Drugs, researchers found a direct correlation between mystical experience intensity and significant improvements in psychological flexibility after psychedelic use.

Just noticed there has been another psychedelic church that got "approved" by the DEA (or at least apppears safe from prosecution). Looks like there are 5 legal churches now in the USA, the latest being The Church of the Celestial Heart in California.

No difference in therapeutic effects of psychedelic use between facilitated group ceremonies and raves/festivals... what do yall think? www.sciencedirect.com/science/arti...

New review article about Acceptance & Commitment Therapy for psychosis, for a special issue of PCNA. Co-authored by Daniel Simsion at @latrobeuni.bsky.social www.psych.theclinics.com/article/S019... @myacbs.bsky.social

I grew up on a diet of Scary Stories to Tell in the Dark... I swear these vines covering a lamppost in Wroclaw, Poland are straight out of my childhood nightmares.

The recent FDA rejection of MDMA therapy revealed a critical issue in #psychedelicscience: BIAS. A whopping 90% of participants could guess whether they got MDMA or placebo, and some therapists allegedly discouraged negative reports while encouraging positive ones.

Stan Grof's "apology" for his extensive homophobic writings and a reply from those who demanded it. chacruna.net/an-open-lett...

1/2 In our new Lancet Psychiatry paper on the brain disease model for addiction, we discuss -its weak empirical support -its downplaying of psychosocial causes & maintenance factors -issues with the definition of 'brain disease' -numerous ways forward www.sciencedirect.com/science/arti...

New research: Transgender & gender-expansive individuals report naturalistic psychedelic use helped them accept their gender identity through increased self-compassion. "Psychedelics have empowered me to accept my wholeness—my gender is part of that." #psychedelicscience 🧵

As NIH cuts keep happening we should keep this in mind substack.com/@erictopol/n...

Another clinical trial of microdosing, the first-ever placebo-controlled trial of low-dose LSD for ADHD shows no benefit over placebo. Both groups improved significantly, but LSD wasn't more effective than sugar pills. #psychedelicscience

Fascinating new study shows psychedelic use increases loving-kindness meditation practice BUT also increases meditation-related difficulties and impairments. This challenges the simplistic "all positive" narrative. #psychedelicscience