Excited to share our latest publication -- psychedelic drugs can enhance synaptic connectivity of neurons not expressing 5-HT2ARs (but requiring 5-HT2AR expression in the input neurons -- lots in the supplementals too!) www.nature.com/articles/s41...

Our latest manuscript (from www.omarlab.org) is now published and available online -- Long lasting enhancement in reversal learning after a single psychedelic dose pmc.ncbi.nlm.nih.gov/articles/PMC...

Did you go to #GRCpsychedelics and not get soap? Don't worry, our themed soap will be ready in 2-3 weeks. Mouse brain toppers, rainbow swirl, dendrite+spine embed. Happy to send a free bar to ~10 people/ attendees. These are handmade by an amateur, so expect imperfections.

Somehow we got almost all the students and postdocs in one photo!! Until next time #GRCPsychedelics 🫡

#GRCPsychedelics is squad goals !! I learned so much, laughed even more, and slept even less Grateful for the new connections, strengthening of old ones and for the opportunity to view my favorite topics from a different lens.

A starter pack including all attendees (that I can find for now) Please let me know if I missed anyone! #GRCPsychedelics go.bsky.app/2ExXJcr

Awhile back we started a Slack group for psychedelic science. Researchers used it to organize meetups and panels at conferences. We discuss papers, including a lively discussion now of the Lu et al. preprint. DM @mikaelpalner.bsky.social or I if you work in academia and want to join

Our latest study identifies a specific cell type and receptor essential for psilocybin’s long-lasting neural and behavioral effects 🍄🔬🧠🧪 Led by Ling-Xiao Shao and @ItsClaraLiao Funded by @NIH @NIMHgov 📄 Read in @nature.com - www.nature.com/articles/s41... 1/12

Our latest preprint -- a single psychedelic dose induces a long-lasting improvement in reversal learning ability www.biorxiv.org/content/10.1...

Our latest work led by @claraliao.bsky.social is a collaboration with the other Kwan lab @kwanlab.bsky.social We used single-nucleus RNA sequencing to measure transcriptional responses in the mouse medial frontal cortex following a single dose of psilocybin. 🍄 🧠 🧬 www.biorxiv.org/content/10.1...

Psilocybin slows and reduces complexity of neural dynamics in medial prefrontal cortex. New paper with Ross Purple, Rahul Gupta, Matt Jones & Co.

Short- and long-term reconfiguration of rat prefrontal cortical networks following single doses of psilocybin https://www.biorxiv.org/content/10.1101/2024.12.10.627734v1

Our preprint on psychedelic control of prefrontal cortex pyramidal neurons! (from www.omarlab.org) www.biorxiv.org/content/10.1...