#Research Readings: Post-traumatic stress and genetic interactions affect tobacco and alcohol use after trauma: findings from a multi-ancestry cohort https://www.nature.com/articles/s41398-025-03593-z#Research

#Research Readings: Impaired speaking-induced suppression predicts degraded agency and #hallucination severity in #schizophrenia https://pmc.ncbi.nlm.nih.gov/articles/PMC11482870/

⏰ STARTS IN 1 HR ⏰ UCSF DPBS Trainee Research Award Presentations with Alexandra Klein, PhD and Chimno Nnadi, MD, PhD. To access the Zoom livestream, visit psychiatry.ucsf.edu/watchgrandrounds

Congratulations to our newly matched Adult Psychiatry Residency Training Program Class of 2030! We can't wait to see you here in San Francisco this June. https://ow.ly/kIoe50YztVc

#Research Readings: Clozapine-associated #neutropenia prevalence in a large, integrated healthcare system https://pubmed.ncbi.nlm.nih.gov/41137791/

#Research Readings: Clinical setting of initial psychotic spectrum disorder diagnoses in an integrated health system https://pubmed.ncbi.nlm.nih.gov/41289289/#Research

What is interoception? Find out during 2026 Trainee Research Award recipient Alexandra Klein's presentation, "Control of Fear States and Underlying Neural Dynamics by Respiratory Rhythms" - Tuesday, April 7 @ 8:30 a.m. PDT https://ow.ly/4kBx50YwtYR

A new study is dampening some of the hype surrounding psychedelic therapy. It found that drugs like LSD and psilocybin are only as good as — but no better than — antidepressants when it comes to treating major depression. https://psychiatry.ucsf.edu/news/are-psychedelics-better-antidepressants

#Research Readings: The placental transcriptome serves as a mechanistic link between prenatal phthalate exposure and placental efficiency https://pubmed.ncbi.nlm.nih.gov/41275761/

#Research Readings: Productivity benefits of treatment of depression and post-traumatic stress disorder in Kenya https://pmc.ncbi.nlm.nih.gov/articles/PMC12584567/

2026 Trainee Research Award recipient Chimno Nnadi, MD, PhD will explore possible uses of machine learning and behavioral data during her talk, "From Receptors to Behavior: Rethinking Drug Discovery in Psychiatry" - Tuesday, April 7 @ 8:30 a.m. PDT https://calendar.ucsf.edu/event/260407gr

#Research Readings: Integrating expert knowledge into large language models improves performance for psychiatric reasoning and diagnosis https://www.sciencedirect.com/science/article/pii/S0165178125004895#Research

We regret that due to circumstances beyond our control, the 2026 Robert S. Wallerstein Lecture in Psychoanalysis and Psychotherapy has been canceled. At this time, we do not anticipate being able to reschedule this year’s event for another date.

"With better biomarkers and safer medications, early treatment at the high-risk stage may ultimately lessen the symptoms of schizophrenia or even prevent it," says DPBS researcher Daniel Mathalon, PhD, MD https://ow.ly/S3UA50Yztgm

#Research Readings: Noncanonical neural-hemodynamic coupling by default and in #Schizophrenia https://www.biologicalpsychiatrycnni.org/article/S2451-9022(25)00359-3/fulltext#Research

Join us this Wednesday at 1 p.m. PDT for the 2026 Robert S. Wallerstein Lecture in Psychoanalysis and Psychotherapy, featuring psychologist and noted health policy expert Kimberlyn Leary, PhD, MPA. It's free and open to the public, but registration is required. Streaming available.

Congratulations to our newly matched Adult Psychiatry Residency Training Program Class of 2030! We can't wait to see you here in San Francisco this June. https://ow.ly/kIoe50YztVc

2026 Trainee Research Award recipient Chimno Nnadi, MD, PhD will explore possible uses of machine learning and behavioral data during her talk, "From Receptors to Behavior: Rethinking Drug Discovery in Psychiatry" - Tuesday, April 7 @ 8:30 a.m. PDT https://calendar.ucsf.edu/event/260407gr

A new study is dampening some of the hype surrounding psychedelic therapy. It found that drugs like LSD and psilocybin are only as good as — but no better than — antidepressants when it comes to treating major depression. https://ow.ly/shNX50YzsVC

#Research Readings: Relationships of patient risk profiles and receipt of specialty treatment with early, sustained, and stable cessation of heavy alcohol use across populations https://pubmed.ncbi.nlm.nih.gov/41274348/#Research

Join us next Wednesday (April 1) at 1 p.m. PDT for the 2026 Robert S. Wallerstein Lecture in Psychoanalysis and Psychotherapy, featuring psychologist and noted health policy expert Kimberlyn Leary, PhD, MPA. It's free and open to the public, but registration is required. Streaming available.

#Research Readings: “You're Not Crazy”: A case of new-onset AI-associated #psychosis https://pmc.ncbi.nlm.nih.gov/articles/PMC12863933/#Research

#Research Readings: Protocol for a randomized controlled trial of a combined motivational interviewing and behavioral couples therapy intervention to reduce intimate partner violence and alcohol use in south India https://pubmed.ncbi.nlm.nih.gov/41325490/

What is interoception? Find out during 2026 Trainee Research Award recipient Alexandra Klein's presentation, "Control of Fear States and Underlying Neural Dynamics by Respiratory Rhythms" - Tuesday, April 7 @ 8:30 a.m. PDT https://ow.ly/4kBx50YwtYR

#Research Readings: Effects of #Hatha #Yoga vs physical conditioning on #sleep in women with urinary incontinence: A secondary analysis of a randomized clinical trial https://pubmed.ncbi.nlm.nih.gov/41359336/#Research

We join the #UCSF and global scientific communities in mourning the passing of UCSF Chancellor Emeritus J. Michael Bishop, MD. https://www.ucsf.edu/news/2026/03/431646/nobel-winning-cancer-researcher-michael-bishop-dies-at-90

#Research Readings: Predicting #TraumaticBrainInjury post-trauma using temporal attention on sleep-wake data https://pubmed.ncbi.nlm.nih.gov/40705576/#Research

People whose brains age faster than they do are more likely to develop #dementia later in life, according to a new study by UCSF researchers. https://ow.ly/e6mq50Ywz2J

UCSF's Dan Mathalon believes that burgeoning knowledge about biomarkers — biological measures of a medical condition that also serve as markers of treatment effectiveness — could help us intercept #schizophrenia and tailor treatment to each patient’s level of risk. https://ow.ly/CV6250YvskK

#Research Readings: Development and validation of a machine learning model to identify individuals at high risk for psychotic disorders using medical record data https://pubmed.ncbi.nlm.nih.gov/41668079/#Research

People whose brains age faster than they do are more likely to develop dementia later in life, according to a new study by UCSF researchers. https://ow.ly/HKOb50Ywz2H

Join us on April 7 for the second half of our 2026 Trainee Research Award Presentations, featuring talks by Alexandra Klein, PhD, and Chimno Nnadi, MD, PhD https://ow.ly/1ymo50YwtoM #research #neuroscience #psychiatry

#Research Readings: Factors influencing pediatric primary care providers' perceived capacity to address behavioral health needs https://pubmed.ncbi.nlm.nih.gov/41331831/

Research has found that exposure to stress affects children differently depending on factors like age, caregiver-child relationships, and neighborhood quality. Supporting caregivers and investing in early-life interventions can lead to better lifelong outcomes. https://ow.ly/k6SP50Y5Jyh

#Research Readings: Enhanced prenatal care models and postpartum depression The EMBRACE randomized clinical trial https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2845125

UCSF's Dan Mathalon believes that burgeoning knowledge about biomarkers — biological measures of a medical condition that also serve as markers of treatment effectiveness — could help us intercept #schizophrenia and tailor treatment to each patient’s level of risk. https://ow.ly/CV6250YvskK

#Research Readings: Development and validation of a machine learning model to identify individuals at high risk for psychotic disorders using medical record data https://pubmed.ncbi.nlm.nih.gov/41668079/

#Research Readings: Plasma placental growth factor as a susceptibility biomarker for longitudinal cognitive change https://alz-journals.onlinelibrary.wiley.com/doi/abs/10.1002/alz.70936#Research

#Research Readings: The Waiting Room Effect: Why diverting people with mental illness from jails requires broad structural and systemic change https://psychiatryonline.org/doi/10.1176/appi.ps.20240386#Research

#Research Readings: Adopting a cascade-of-care approach to examine mental health service access for youths in the child welfare system https://psychiatryonline.org/doi/full/10.1176/appi.ps.20240487#Research

⏰ STARTS IN 1 HR ⏰ UCSF DPBS #GrandRounds – "Pediatric Mental Health Emergencies" with Jennifer A. Hoffmann, MD. To access the Zoom livestream, visit psychiatry.ucsf.edu/watchgrandrounds

#Research Readings: Predicting traumatic brain injury post-trauma using temporal attention on sleep-wake data https://pubmed.ncbi.nlm.nih.gov/40705576/#Research

⏰ STARTS IN 1 HR ⏰ UCSF DPBS #GrandRounds – “Interpersonal Psychopharmacology: Prioritizing Life, Recovery, and the Relationship in the Care of the Person Experiencing Homelessness” with Anthony Carino, MD. To access the Zoom livestream, visit psychiatry.ucsf.edu/watchgrandrounds#GrandRounds

#Research Readings: Treatment of disturbed sleep in progressive supranuclear palsy: a randomized, remote, double-blinded, 6-week cross-over design study protocol comparing zolpidem, suvorexant, and placebo https://pubmed.ncbi.nlm.nih.gov/41501928/#Research

#Research Readings: Trauma and resilience among Latiné girls: A mixed methods exploration of Positive Adaptations for Trauma and Healing (PATH) https://ow.ly/hKls50YhLh7#Research

Next week, join us on Wednesday 3/11 for our next Distinguished Visiting Child and Adolescent Lecturer Series #GrandRounds – “Pediatric Mental Health Emergencies” with Jennifer A. Hoffmann, MD. More info here, https://calendar.ucsf.edu/event/260311gr#GrandRounds

#Research Readings: Daughters-in-law’s perceptions and experiences with MILAP, a family-based intervention to reduce intimate partner violence and improve mental health in Nepal https://link.springer.com/article/10.1007/s00737-025-01643-5#Research

Our next DPBS #GrandRounds – “Interpersonal Psychopharmacology: Prioritizing Life, Recovery, and the Relationship in the Care of the Person Experiencing Homelessness” with Anthony Carino, MD – is scheduled for March 10. To access the livestream, visit psychiatry.ucsf.edu/watchgrandrounds#GrandRounds

#Research Readings: A qualitative exploration of community perception on dementia and dementia care in Nepal https://academic.oup.com/innovateage/article/9/Supplement_2/igaf122.4053/8409016#Research

#Research Readings: Editorial: Keeping time with the 24-hour brain: what rest-activity rhythms reveal about #Dementia risk https://www.neurology.org/doi/10.1212/WNL.0000000000214599#Research