1) How do we capture the “golden goose” of interaction proteomics-dynamic, context-dependent PPI networks? Faster data acquisition and deep learning are transforming interactomics. Our review in Molecular Omics highlights recent advances and future directions.

Congratulations to John R. Yates III, Ruedi Aebersold and Matthias Mann, recipients of the 2026 Canada Gairdner International Award. Prof. Yates: www.gairdner.org/winner/john-... Prof. Aebersold: www.gairdner.org/winner/ruedi... Prof. Mann: www.gairdner.org/winner/matth... #2026GairdnerAwards

Direct interaction between TDP-43 and Tau promotes their co-condensation, while suppressing Tau fibril formation and seeding @dormannlab.bsky.social www.embopress.org/doi/full/10....

SARS-CoV-2 main protease (Mpro) directly activates coagulation by cleaving factors VII and XII, showing a broader protease specificity and revealing a novel mechanism linking COVID-19 infection to thrombosis. doi.org/10.1038/s420...

New work out in @commsbio.nature.com @natureportfolio.nature.com! With Anna Pagotto, we show SARS-CoV-2 Mpro has a secondary preference for R↓ beyond LQ↓. This broader specificity can directly activate the coagulation cascade. #Biochem & #Proteomics all in! www.nature.com/articles/s42... (1/2)

Direct binding of TDP-43 and Tau drives their co-condensation, but suppresses Tau fibril formation and seeding www.biorxiv.org/content/10.1...

Direct binding of TDP-43 and Tau drives their co-condensation, but suppresses Tau fibril formation and seeding https://www.biorxiv.org/content/10.1101/2025.07.07.662960v1

PKA regulates stress granule maturation to allow timely recovery after prolonged starvation https://www.biorxiv.org/content/10.1101/2025.07.06.663161v1

Hello Bluesky! 🌤️ We're on the Molecular Cell cover! How are ribosome levels adjusted? Stm1 not only protects ribosomes from degradation, it also promotes their biogenesis in nutrient-rich conditions. Two roles, one protein - tuned by nutrient availability. 🔗 www.cell.com/molecular-ce...

🚨Registration for the 13th Symposium on Structural Proteomics is open! Milan, Oct 6–8 | Cutting-edge science and vibrant discussions. ssp2025.squarespace.com Proud to co-organize the SSP in Italy with Andrea Graziadei and Lolita Piersimoni @humantechnopole.bsky.social #ChiesiFarmaceutici #univaq

Interested in the molecular mechanisms of neurodegeneration? 📢 We are looking for a PhD student interested in studying the role of TDP-43 in genome stability and the DNA damage response! Apply via this fantastic PhD Programme until April 3 👇

One more day to apply!

Hi Blueskyers! Excited to share our work in @naturecomms.bsky.social. With the group of Michel Steinmetz(PSI) we combined quantitative XL-MS and biophysics to reveal how Bik1 dynamically rearranges in dilute and phase separated state. www.nature.com/articles/s41... (1/2) #TeamMassSpec#idp#PhaseSep

📢 The Dormann Lab is looking for a PhD student interested in the molecular mechanisms of neurodegeneration and biomolecular condensation! Interested in one of our research projects on disease-linked RNA-binding proteins, such as TDP-43 and FUS? Apply to this fantastic PhD program by February 7 👇

Pericentromeric #heterochromatin clusters into chromocenters. @skrutlnize.bsky.social &co use quantitative mass spec to characterize the chromocenter proteome in multiple tissues, identifying a link between satellite DNA-binding proteins & #transposon repression🧪 @plosbiology.org plos.io/4akuNAi