Alison Harrod
@alison-harrod.bsky.social
📤 88
📥 148
📝 5
Postdoctoral Training Fellow in the Downs Lab at the Institute of Cancer Research, London
Our new review, looking into the roles of SWI/SNF in the chromatin environment around centromeres, is just out in Open Biology!
@kezlane.bsky.social
@thedownslab.bsky.social
add a skeleton here at some point
about 1 month ago
0
5
3
reposted by
Alison Harrod
The Downs Lab
2 months ago
The amazing
@lillianwu.bsky.social
is now the amazing Dr Lillian Wu 🎉 She passed her viva with flying colours. Massive thanks to her wonderful examiners
@esashilab.bsky.social
and
@viji-draviam.bsky.social
0
18
2
reposted by
Alison Harrod
The Downs Lab
2 months ago
Congratulations to Dr Noa Amin (times two since she was already a medical doctor but now has an amazing PhD)!!!
#proudsupervisor
Beautiful
@icr.ac.uk
award ceremony at the Guildhall
0
11
3
It was a pleasure to present my work at the AlterNAT meeting last week! Thank you to the organisers for a really interesting meeting, and for the opportunity to present my work.
@biochemsoc.bsky.social
add a skeleton here at some point
6 months ago
0
7
0
reposted by
Alison Harrod
The Downs Lab
6 months ago
A little shout-out to the lab, who have been out in force lately presenting their work! Starting with @alison-harrod.bsky.social talking about her work with Pedro Zuazua Villar and @naghamg.bsky.social on SMARCA4 and G quadruplexes
1
13
4
reposted by
Alison Harrod
The Downs Lab
8 months ago
New preprint from the lab on ARID1A, G quadruplexes, and repair:
www.biorxiv.org/content/10.1...
loading . . .
ARID1A stabilises non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin
ARID1A is a subunit of the BAF chromatin remodelling complex that is frequently mutated in cancer. It is challenging to predict how ARID1A loss impacts cancer therapy response because it participates ...
https://www.biorxiv.org/content/10.1101/2025.05.10.653238v1
0
20
11
reposted by
Alison Harrod
The Downs Lab
10 months ago
If you like chromatin remodellers and centromeres, this might be of interest. In it, we generated omics data from isogenic PBRM1 cell lines, which we hope is of use to the community, freely available (when evil forces aren't messing with the publicly funded websites 🙄)
www.nature.com/articles/s41...
loading . . .
PBRM1 directs PBAF to pericentromeres and protects centromere integrity - Nature Communications
Centromere fragility can drive tumourigenesis, so protective mechanisms are important. Here, the authors suggest that the PBAF chromatin remodelling complex, which is frequently misregulated in cancer...
https://www.nature.com/articles/s41467-025-57277-9
2
34
11
reposted by
Alison Harrod
Karen Lane
10 months ago
Delighted to share that our paper on the role of PBAF in centromere integrity is out now in
@natcomms.bsky.social
! It was a long journey but it was made so much easier thanks to my co-first author/coding whiz
@alison-harrod.bsky.social
, the whole
@thedownslab.bsky.social
team, & our wonderful boss!
loading . . .
PBRM1 directs PBAF to pericentromeres and protects centromere integrity
Nature Communications - Centromere fragility can drive tumourigenesis, so protective mechanisms are important. Here, the authors suggest that the PBAF chromatin remodelling complex, which is...
https://rdcu.be/eb0ro
4
12
3
Cheers
@kezlane.bsky.social
to our co-first author paper on PBRM1 and the centromere being published this week in
@naturecomms.bsky.social
!
@thedownslab.bsky.social
@icr.ac.uk
10 months ago
2
10
1
reposted by
Alison Harrod
Ronan Broderick
11 months ago
My lab is
#hiring
! I am recruiting for two
#Postdoc
positions investigating the Alternative Lengthening of Telomeres mechanism.
www.jobs.ac.uk/job/DLO693/r...
www.jobs.ac.uk/job/DLP016/r...
#Telomere
#DNAreplication
#DNArepair
#cancer
#glioma
#UKRI
#MRC
#universityofbirmingham
#NGS
loading . . .
Research Fellow at University of Birmingham
Discover an exciting academic career path as a Research Fellow at jobs.ac.uk. Don't miss out on this job opportunity - apply today!
https://www.jobs.ac.uk/job/DLO693/research-fellow
0
11
11
reposted by
Alison Harrod
The Downs Lab
about 1 year ago
We are looking for someone to join our lab as a researcher (scientific officer). Advert and information on applying is here:
jobs.icr.ac.uk/vacancies/10...
It's a great team and a wonderful place to work!
loading . . .
Scientific Officer - Epigenetics and Genome Stability in Chelsea | The Institute of Cancer Research
View details and apply for this Scientific Officer - Epigenetics and Genome Stability vacancy in Chelsea . Salary : Commencement on the salary range is subject to comparable skills and exp...
https://jobs.icr.ac.uk/vacancies/1087/scientific-officer--epigenetics-and-genome-stability.html
1
19
19
reposted by
Alison Harrod
The Downs Lab
about 1 year ago
Lab retreat 2024! We had days of excellent science, food, ideas, food, games, food, discussions, food, and brainstorming. And snacks.
0
17
2
you reached the end!!
feeds!
log in