Karen Lane
@kezlane.bsky.social
π€ 78
π₯ 145
π 12
Postdoc
@icr.ac.uk.bsky.social
in
@thedownslab.bsky.social
π¬π§ͺπ₯Όπ©π»βπ¬π§«
reposted by
Karen Lane
Luijsterburglab
4 months ago
Great response so far for the DNA Repair Meeting in April 2026 ! 𧬠A few poster spots are still available. ⨠Early-bird registration extended to February 28th ⨠New invited speakers added: check the site:
dnarepairmeeting-egmond2026.com
Donβt miss this outstanding meeting!
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Thanks
@icr.ac.uk
, we are in very good company on this list βΊοΈπΎ
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Scientific achievements of 2025
Scientific achievements of 2025
https://www.icr.ac.uk/about-us/icr-news/detail/scientific-achievements-of-2025
6 months ago
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Some Friday reading...new review in Open Biology where we discuss how SWI/SNF maintains the chromatin environment around centromeres, building on recent work from ourselves and others. Lots of fun putting this together with
@alison-harrod.bsky.social
and
@thedownslab.bsky.social
!
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Boundary issues: SWI/SNF shapes chromatin patterns in and around centromeres
Abstract. The SWI/SNF family of chromatin remodelling complexes, comprising BAF, PBAF and ncBAF, is known for their critical roles in regulating chromatin
https://royalsocietypublishing.org/rsob/article/15/12/250186/363283/Boundary-issues-SWI-SNF-shapes-chromatin-patterns
6 months ago
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reposted by
Karen Lane
James Gahan
11 months ago
We are looking for new colleagues to come join us in Galway as group leaders (Junior and Senior). The Centre for Chromosome Biology is a great place and it is a good time to join. Please reach out if you want to chat about the opportunity!
www.nature.com/naturecareer...
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A busy 6 weeks spreading exciting results from myself and
@thedownslab.bsky.social
π
11 months ago
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Delighted to share that our paper on the role of PBAF in centromere integrity is out now in
@natcomms.bsky.social
! It was a long journey but it was made so much easier thanks to my co-first author/coding whiz
@alison-harrod.bsky.social
, the whole
@thedownslab.bsky.social
team, & our wonderful boss!
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PBRM1 directs PBAF to pericentromeres and protects centromere integrity
Nature Communications - Centromere fragility can drive tumourigenesis, so protective mechanisms are important. Here, the authors suggest that the PBAF chromatin remodelling complex, which is...
https://rdcu.be/eb0ro
about 1 year ago
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reposted by
Karen Lane
The Institute of Cancer Research
over 1 year ago
π We're getting in on the act with an ICR research
#StarterPack
. Check it out! β€΅οΈ Let us know if you're a
#cancer
researcher at the ICR and The Royal Marsden but not in the pack. π¬
#CancerResearch
#CanSky
#OncSky
go.bsky.app/EGXU5V1
add a skeleton here at some point
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reposted by
Karen Lane
The Downs Lab
over 1 year ago
We are looking for someone to join our lab as a researcher (scientific officer). Advert and information on applying is here:
jobs.icr.ac.uk/vacancies/10...
It's a great team and a wonderful place to work!
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Scientific Officer - Epigenetics and Genome Stability in Chelsea | The Institute of Cancer Research
View details and apply for this Scientific Officer - Epigenetics and Genome Stability vacancy in Chelsea . Salary : Commencement on the salary range is subject to comparable skills and exp...
https://jobs.icr.ac.uk/vacancies/1087/scientific-officer--epigenetics-and-genome-stability.html
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