Karen Lane
@kezlane.bsky.social
π€ 72
π₯ 137
π 12
Postdoc
@icr.ac.uk.bsky.social
in
@thedownslab.bsky.social
π¬π§ͺπ₯Όπ©π»βπ¬π§«
Thanks
@icr.ac.uk
, we are in very good company on this list βΊοΈπΎ
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Scientific achievements of 2025
Scientific achievements of 2025
https://www.icr.ac.uk/about-us/icr-news/detail/scientific-achievements-of-2025
15 days ago
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Some Friday reading...new review in Open Biology where we discuss how SWI/SNF maintains the chromatin environment around centromeres, building on recent work from ourselves and others. Lots of fun putting this together with
@alison-harrod.bsky.social
and
@thedownslab.bsky.social
!
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Boundary issues: SWI/SNF shapes chromatin patterns in and around centromeres
Abstract. The SWI/SNF family of chromatin remodelling complexes, comprising BAF, PBAF and ncBAF, is known for their critical roles in regulating chromatin
https://royalsocietypublishing.org/rsob/article/15/12/250186/363283/Boundary-issues-SWI-SNF-shapes-chromatin-patterns
25 days ago
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reposted by
Karen Lane
James Gahan
6 months ago
We are looking for new colleagues to come join us in Galway as group leaders (Junior and Senior). The Centre for Chromosome Biology is a great place and it is a good time to join. Please reach out if you want to chat about the opportunity!
www.nature.com/naturecareer...
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A busy 6 weeks spreading exciting results from myself and
@thedownslab.bsky.social
π
6 months ago
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Delighted to share that our paper on the role of PBAF in centromere integrity is out now in
@natcomms.bsky.social
! It was a long journey but it was made so much easier thanks to my co-first author/coding whiz
@alison-harrod.bsky.social
, the whole
@thedownslab.bsky.social
team, & our wonderful boss!
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PBRM1 directs PBAF to pericentromeres and protects centromere integrity
Nature Communications - Centromere fragility can drive tumourigenesis, so protective mechanisms are important. Here, the authors suggest that the PBAF chromatin remodelling complex, which is...
https://rdcu.be/eb0ro
10 months ago
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reposted by
Karen Lane
The Institute of Cancer Research
about 1 year ago
π We're getting in on the act with an ICR research
#StarterPack
. Check it out! β€΅οΈ Let us know if you're a
#cancer
researcher at the ICR and The Royal Marsden but not in the pack. π¬
#CancerResearch
#CanSky
#OncSky
go.bsky.app/EGXU5V1
add a skeleton here at some point
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reposted by
Karen Lane
The Downs Lab
about 1 year ago
We are looking for someone to join our lab as a researcher (scientific officer). Advert and information on applying is here:
jobs.icr.ac.uk/vacancies/10...
It's a great team and a wonderful place to work!
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Scientific Officer - Epigenetics and Genome Stability in Chelsea | The Institute of Cancer Research
View details and apply for this Scientific Officer - Epigenetics and Genome Stability vacancy in Chelsea . Salary : Commencement on the salary range is subject to comparable skills and exp...
https://jobs.icr.ac.uk/vacancies/1087/scientific-officer--epigenetics-and-genome-stability.html
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