OFERTA DE EMPLEO (por favor difundir): Ofrecemos un contrato predoctoral de 4 años asociado a nuestro proyecto PID2024-157249OB-I00. El objetivo del proyecto es evaluar un nuevo mecanismo patológico según el cual la competición entre promotores puede llegar a ocasionar enfermedades congénitas 👇

NEW PAPER Out in Science Advances: We have dissected the physiological role of all macroH2A histone variants. In mice, loss of macroH2A1.1 specifically results in profound metabolic reprogramming and kidney pathology. DOI: 10.1126/sciadv.adz1242 Thread 1/7

True in 9 out of 10 cases.

MEET THE LAB! This week our postdoc René Winkler will attend the @febspress.bsky.social workshop 'Molecular and cellular pathways of aging in hematopoiesis' on Crete, Greece. René will present work led by @shubhra.bsky.social on how cohesin mutations impact MDS progression.

MEET THE LAB Today Marina Farkas is attending the "Molecular Haemopoiesis" meeting at the Francis Crick Institute in London, UK. A gathering of researchers studying #blood development, with a particular focus on blood stem cell biology, gene regulation and #leukaemia.

We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3

Adios and salut to a pioneer! Sir John Gurdon studied the requirements and barriers of #reprogramming. Highly relevant for us, with his PhD student Vincent Pasque he showed that macroH2A is part of the epigenetic barrier inhibiting reprogramming. Our thoughts are with his family and friends.

NEW TEAM MEMBER! We welcome Bedri Batuhan Yaman to the group. Bedri will study the role of nuclear metabolism in #AML. He is co-supervised by @florherbstein.bsky.social and fellow of the MSCA @nucleardn.bsky.social. Bedri is alumnus of @viblifesciences.bsky.social (Belgium) and NeuroBM (Turkey).

Looking for scientists working with long-read transcriptomics technologies to join a COST action proposal. Contact us!!! @nanoporetech.com @pacbio.bsky.social

We have a new PhD studentship in the lab on the immunogenic roles of transposable elements in paediatric acute myeloid leukaemia! Come and work with us! www.colcc.ac.uk/2026-cyp-phd...

FAREWELL! After 6 month of Master research, Francesco B. Ciriscioli is returning to his home university in Triest, Italy. Thank you, Francesco, for your interesting results and for having enriched our group with your kind personality. We wish you all the best!

Great weather at daytime and northern lights at night time illuminate the scientific kick-off of the #HubMOL #MSCA doctoral network. On Someroy, a small island at the Artic Coast of Norway, we learn about the dual role of molecules such as NAD and SAM in signalling and metabolism.

MEET THE LAB! During the next 3 days, I am in northern Norway at the kick-off workshop of the HubMOL consortium. This MSCA doctoral network coordinated by Ines Heiland, University of Tromsø, aims to gain a better understanding of the dual role of NAD, CoA and co. in metabolism and signalling.

What a great first day at the GfG symposium on epigenetics & chromatin. Fantastic talks by @akispapantonis.bsky.social , @apombo1.bsky.social, @marcusbuschbeck.bsky.social and Philipp Korber. And Peter Becker giving the Max-Delbrueck lecture. A real treat for the audience!

NEW DOCTOR IN TOWN! Congratulations to Lejuan Shi from Sonia Forcales' lab who has defended her thesis today. As chair of her defense committee with Concepcio Soler and @tanyavavouri.bsky.social, I had the opportunity to discuss with Lejuan about the role of lncRNAs in cancer.

NEW LAB MEMBER! We welcome ‪@florherbstein.bsky.social who is joining us as a‬ ‪@carrerasleaders.bsky.social‬ Postdoctoral Fellow. She is alumni of #IBioBA-MPSP and the University of Buenos Aires.‬‬ She will study how nuclear metabolism influences proliferation and therapy resistance in AML.

Last 10 days to apply for this PhD position in medicinal chemistry!

OPPORTUNITY for a CHEMIST to JOIN US Are you interested in: 👍 Computer-aided ligand design 👍 Organic synthesis 👍 Biomedicine 👍 Drug development 👍 A multidisciplinary team 👍 And a PhD in Barcelona Then check this out! rb.gy/nc3lf3

'NEW' LAB MEMBER! Our 2022 technician trainee Julia Ledesma is back. Julia is using the summer break of her biology studies at the University of Barcelona to help us advancing our projects as auxiliary technician. Thanks a lot, Julia.

Poster presentations by professors and group leaders for politicians. Maybe something we scientists should do in every country to make sure our elected representatives know what we are aiming to do.

BREAKING: Scientists are staging a “science fair” in the lobby of a Congressional building to tell elected officials about the critical knowledge the US will lose because their research grants have been canceled.

We wrote a review on Transposable Elements (TEs) and almost all aspects of TE silencing and their roles in biological processes & disease. www.nature.com/articles/s41...

3 PhD opportunities in nuclear metabolism. Check it out!

It is a great honor and greater responsibility to take over the chair of the #EHA research committee from Brian Huntly and Ruud Delwel. Together with Dominique Bonnet I will lead the committee dealing with all aspects of research at #EHA.

Today at #EHA2025 For the first time in a decade And maybe the last time for the next I will present a poster. If you are interested in what cohesin mutations do in MDS, then join me at poster #PS1606. Work led by PhD candidate Shubhrs Bhattacharya.

The @carrerasijc.bsky.social delegation is more active than ever at #EHA2025!

Meet me there!

🧪 Symposium of the German Society for Genetics, a very special event this year! Max Delbrück Lecture by Peter Becker and with a focus on Epigenetics and Chromatin. Sept 24 – 26, 2025 | JLU Giessen, Germany Abstract deadline: July 15, 2025

MEET THE TEAM. René Winkler and Marcus Buschbeck will attend #EHA2025 congress in Milan. Find us at: JUN 12 - Mol Hemato workshop, Brown 3 JUN 13 - EHA-ISEH Joint Symposium, Amber 7 JUN 14 - YoungEHA, Brown Hall 2 + Poster 1606 JUN 15 - Myeloid Neoplasia, Brown 1

MEET THE LAB Did you know that we have also one project in Ewing's Sarcoma? IF ✅ you share this interest, ✅ you are at #EUSARC2025 in Venice, THEN 👉 reach out to Jonathan and learn more about what we do.

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯 Any lab using @flybase.bsky.social please donate using the link in post below. This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

If you are interested in #3DGenomics #4DNucleomics and want to help us dig into this fascinating world.... visit our Web site marciuslab.org and drop us an email to apply together for a Marie Skłodowska-Curie postdoc fellowship 👇🏼 marie-sklodowska-curie-actions.ec.europa.eu/actions/post...

Interesting method for RNA modification aficionados.

New Harvard alum group formed to fight back and form alliances with other unis See link about an online organizing event this week www.crimsoncourage.com

Unique opportunity for managers! Please RP! We at @carrerasijc.bsky.social are hiring a Managing Director! Lead the institute's management to the next level and help its scientists and clinicians to advance on cures of blood cancers. > careers.carrerasresearch.org/jobs/5915609...

Thank you, Mathias Ziegler, for having hosted me as a guest speaker of CCBIO at University of Bergen. It was great to learn about the latest in NAD metabolism. Looking foward to more interactions through the MSCA networks @nucleardn.bsky.social and HubMOL.

MEET THE LAB! During the next three days I will be at the Universities of Oslo and Bergen in Norway. Thanks a lot to Lorena Arranz, @ragnhildes.bsky.social and MathiasZiegler for hosting me.

Looking forward to sharing our work from @arztlab.bsky.social at UCA-BIOMED next week! Many thanks to Karina Formoso for the invitation.

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

MEET THE TEAM! Today half of the lab is at the @scb.iec.cat attending the 15th Chromatin and Epigenetics Day. Kudos to Albert Jordan for organizing. This is a fixed event in the lab's calender. In the pic below Ollie is presenting his results.

Postdoc opportunity at our institute! 3 year fully funded MSCA fellowship available. Check out the more than 20 available groups! V V V

I am excited to share our lab's first review out with in Blood Cancer Journal. We discuss the impact of transposable elements on genome regulation and variation in both normal haematopoietic processes and haematological cancers. www.nature.com/articles/s41...

Our lab is expanding! We are looking for an experimental or computational PhD student and a Technical Assistant for a project on RNA localization regulation. Details 👉 shorturl.at/fWH3u ⏳ +1 more PhD spot still open—10 days left to apply! shorturl.at/Udw0Q #PhD

MEET THE LAB and more! Sonia Nuñez, Marcus and our colleague Tanya Vavouri travelled to beautiful but rainy Bergen to interview the top-ranked candidates for the MSCA doctoral network HubMOL at UiB. Congratulations to all candidates for great presentations and good luck!

Deaths from heart disease down 75%, that’s NIH. Deaths from stroke down 75%, that’s NIH. HIV/AIDS no longer a death sentence, that’s NIH. 99% of FDA approved drugs in the last decade, that’s NIH. Please show this video to anyone who doesn’t understand why the NIH is so important.

Amazing opportunity to join @carrerasleaders.bsky.social postdoctoral programme in blood cancers. Apply at www.carrerasleaders.eu by 1 June! #WeAreNCL #WeAreFMS

NOW or NEVER! Last opportunity to join the @CarrerasIJC through this exceptional, fully funded @MSCActions postdoc program!

Congratulations, Biola. Well deserved!

We welcome Ari Melnick as our new director at @carrerasijc.bsky.social. Together we will study molecular mechanisms of blood cancers and exploit this knowledge to advance on their cures.