Bhawik Jain
@jainbhawik.bsky.social
📤 15
📥 26
📝 3
Cell and Molecular Biologist, Cricket enthusiast
reposted by
Bhawik Jain
Jeremy Baskin
about 2 months ago
To all lipid-curious cell biologists: check out this comprehensive overview of lipid-based methods by
@gerryhammond.bsky.social
and colleagues in
@jcb.org
— a school of Babel fish for
#lipidtime
:
rupress.org/jcb/article/...
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The cell biologist’s guide to detecting and modulating membrane phospholipids | Journal of Cell Biology | Rockefeller University Press
Worcester et al. describe a suite of molecular tools and approaches that can be used to probe and experimentally study lipids.
https://rupress.org/jcb/article/225/2/e202508058/281350/The-cell-biologist-s-guide-to-detecting-and
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reposted by
Bhawik Jain
Nature Cell Biology
7 months ago
🍨Interested in reading more about the study? Here is the N&Vs article written by Michael Salsaa & Gregory D. Fairn. 👉https://rdcu.be/eADFu
bit.ly/45zxHiL
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Phosphoinositide flipping governs neomycin sensitivity - Nature Cell Biology
Neomycin toxicity in eukaryotic cells stems from its binding to phosphoinositides, primarily confined to the inner leaflet of the plasma membrane. New research reveals a complex lipid-trafficking path...
https://bit.ly/45zxHiL
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reposted by
Bhawik Jain
Nature Cell Biology
7 months ago
🍹
@grahamlab-vandy.bsky.social
@jainbhawik.bsky.social
& co report that the Neo1 P4-ATPase flips the
#lipid
PI4P across the
#Golgi
membrane to the cytosolic leaflet, preventing PI4P exposure and thereby conferring neomycin resistance.
bit.ly/45tauP7
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P4-ATPases control phosphoinositide membrane asymmetry and neomycin resistance - Nature Cell Biology
Jain et al. report that the Neo1 P4-ATPase flips the lipid PI4P across the Golgi membrane to the cytosolic leaflet, preventing PI4P exposure and thereby conferring neomycin resistance.
https://bit.ly/45tauP7
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Excited to share our latest work published in
@natcellbio.nature.com
! We identify Neo1 as a novel phosphoinositide flippase that maintains membrane asymmetry and provides resistance to
[email protected]
. Check out the article and News & Views here
rdcu.be/eweby
rdcu.be/eweh9
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P4-ATPases control phosphoinositide membrane asymmetry and neomycin resistance
Nature Cell Biology - Jain et al. report that the Neo1 P4-ATPase flips the lipid PI4P across the Golgi membrane to the cytosolic leaflet, preventing PI4P exposure and thereby conferring neomycin...
https://rdcu.be/eweby
8 months ago
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reposted by
Bhawik Jain
Graham Lab
10 months ago
As April comes to a close, we wanted to share updates for the first quarter of 2025!!
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