Glad to share our latest work that came out recently. We dive into the mechanisms of how Transcription Factors (TFs) like the nuclear receptor, ERα navigate the genome to find their targets.

Epigenetics Update - H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations bit.ly/459lS3k Robert Schneider (Helmholtz München) in Mol Cell #Epigenetics #Chromatin #Metabolism --- Discover the breakthrough at epigenometech.com

Very happy to share our paper rdcu.be/eUImj out today in @natcellbio.nature.com 🎉🎉🎉 We uncover an unexpected role for endogenous Xist RNA in regulating X-linked genes that escape X-inactivation.

Delighted to share our publication in @stemcellreports.bsky.social on the role of #m6A_RNA methylation in #Xchromosome dosage compensation during #embryogenesis, jointly driven by Hemant and @barorunumi.bsky.social. 🔗 www.cell.com/stem-cell-re... @isscr.org 🧵

Elated to share that @sharmistasbio.bsky.social from our lab presented her work on #epigenetic regulation of neurodevelopmental disorders recently at the #BuildingBrains2025 workshop at @iBRIC-inStem. Acknowledge @iiscbangalore, @embo.org, @ANRF-India, @DBTIndia for the support.

We are excited to share our new preprint: SMARCA2/4-Dependent Chromatin Remodelling Establishes Gene Regulatory Programs in Early Human Embryos and Blastoids. www.biorxiv.org/content/10.64898/2025.12.01.691499v1

So exciting to see this in print! Ever wondered how embryonic cells know what (fate) to become during early development? In particular when they might see different signaling cues? We investigated this! And a lovely cover from Zoe Ruiz and @oliveringe.bsky.social! www.cell.com/developmenta...

XCI-ited to share that @Runumi from our lab recently attended the Gordon Research Conference on "Epigenetic Variation: Mechanisms and Impact across Systems" held in Barcelona, Spain. She presented her work on role of #m6A-RNA in #embryogenesis and dosage compensation #X-inactivation.

Thrilled to share that @Avinchal from our lab presented her work on effect of heat-humidity stress on fetal development and #epigenetic regulation in the recent #GordonConference on "Epigenetic Variation: Mechanisms and Impact across Systems" #ClimateChange #GlobalWarming #MaternalChildHealth

Interesting study showing how H3K36me2 modulation is critical for post-implantation DNAme re-establishment. #epigenetics #histone #EarlyDevelopment

Excited to receive the Best Poster Award at the 9th Asian chromatin meeting 2025 in IISER Pune! Huge thanks to my mentor Srimonta for his guidance. Thanks to organizers of #ACM2025 for this wonderful opportunity! #iiscbangalore #EMBO

Runumi, from our lab, had a fantastic week at the @embo.org Epitranscriptome workshop at EMBL Heidelberg! She presented her work on the role of m6A RNA modification in #embryogenesis #stemcell specification and #Xinactivation. #EMBOEpitrans Thanks to IISc, ANRF-India, DBT-India, @insdb.bsky.social