This #ASNCJASN study analyzed the effects of empagliflozin, a diabetes medication, on kidney function in young people with type 2 diabetes (T2D), suggesting that empagliflozin may help prevent early diabetic kidney disease in youth with T2D. Read more: kidney.pub/CJASN0889#ASNCJASN

Mechanistic target of rapamycin complex-2 (mTORc2) mediates the effect of over-night high K+ on Kir4.1/Kir4.1 in the DCT and ENaC/ROMK in ASDN. | American Journal of Physiology-Renal Physiology | American Physiological Society journals.physiology.org/doi/abs/10.1...

Power relations and role boundaries between community first responders and ambulance clinicians in England: a qualitative study - power relations, hierarchy and role boundaries, characterised by subordination of CFRs and collaborative relationships between ambulance staff and CFRs rdcu.be/eR6fK

Our department @ucph.bsky.social is looking for a new faculty member! This is a nice environment for an ambitious PI with a research focus on cardiovascular system, metabolism and/or drug discovery! Happy to answer questions if you are interested!

Wedding Vibes 👰🤵‍♂💒💍 with @paulsquires.bsky.social ..it was a hot one ☀️☀️☀️ #ArdingtonHouse #Oxfordshire #womeninSTEM #annualleave #summertime #UK #Cotswolds #wedding

Stimulating immune cells in vitro is a common experimental lab model. We profiled 150K blood immune cells treated with 11 different stimuli to compare the effects. The data are freely available for researchers. See the preprint for our findings and to access the data 🧪 doi.org/10.1101/2025...

Delighted to have contributed to this editorial diabetesjournals.org/diabetes/art...

Fantastic article to celebrate the contribution of our very own @chillslincoln79.bsky.social to some amazing work on #worldkidneyday, see: news.lincoln.ac.uk/2025/03/13/l...

I have funding through at least 2031 for postdoctoral researchers with expertise in islet biology or cell-based therapies for, or modelling of, diabetes. Bring your expertise to a country that values it. 🇨🇦 Contact info on my website.

Fantastic opportunity for fellowship in an excellent T1D research training environment working in regenerative medicine and stem cells in the Breakthrough T1D Centre of Excellence at UBC. If you missed the NOI deadline, no worries, you can still apply! Reach out if you have any questions.

Effect of #sotagliflozin on major adverse cardiovascular events: a prespecified secondary analysis of the SCORED randomised trial 👩‍🔬🥼🧪👨‍🔬 #cardiosky #SGLT2i #SGLT1/2 #cardiovascular #womeninstem #NephSky 👇👇👇 www.thelancet.com/journals/lan...

A sunday night worth celebrating with @paulsquires.bsky.social after a busy, busy week 🥂🍾. Hopeful that good news will follow 👩‍🔬👨‍🔬🧪 #justbecause #cardiosky #NephSky #womeninSTEM #academic #weekendvibes #champagne ##KidneyResearch #CardioRenal #Cardiovascular

Birthday boy cotswolds celebrations 🥳🥳 @DoubleRedDuke with @paulsquires.bsky.social 🥰🥰 #birthday #cotswolds #England #annualleave #womeninSTEM

📣 Novo Nordisk announces that the FDA has granted approval to its blockbuster drug Ozempic (semaglutide) to treat chronic kidney disease (CKD) in adults with type 2 diabetes. 👩‍🔬🥼🧪👨‍🔬 #Semaglutide #diabetes #type2diabetes #nephropathy #GLP-1 👇👇 docwirenews.com/post/fda-app...

📣 Semaglutide in patients with overweight or obesity and chronic kidney disease without diabetes: a randomized double-blind placebo-clinical trial @naturemedicine.bsky.social 👩‍🔬🥼🧪👨‍🔬 #Semaglutide #KidneyDisease #Obesity #kidney #NephroSky #CardioSky #NephSky 👇👇👇 pubmed.ncbi.nlm.nih.gov/39455729/

BBC News - Meon Vale mother of three who needs kidney makes donor appeal - BBC News www.bbc.co.uk/news/article...

BREAKING NEWS: The FDA has approved Ozempic for patients with chronic kidney disease. This means the popular injection can be used to reduce the risk of kidney disease worsening, kidney failure and death from cardiovascular disease in patients with chronic kidney disease and diabetes.

Congratulations @cardiacshah.bsky.social & co-author @jo-ward08.bsky.social from team #CardioRenal on publication of this all important review - incorporating clinical guidelines with latest evidence & experience in the management of T2DM in patients with ASCVD 🥳🥳🥳🥳. #diabetes #CardioSky #NephSky

Beautiful #Salcombe, it never disappoints. The perfect place to switch off and unwind with @paulsquires.bsky.social 🥰🥰 #Lifeofanacademic #AcademicSky ##CardioSky #WomeninSTEM #England #Devon #SalcombeHarbour #Coastal #Coastline #NephroSky

📣 Congratulations to my PhD student @cardiacshah.bsky.social on his review 'Diagnosis & management of type 2 diabetes mellitus in patients with ischaemic heart disease & acute coronary syndromes - a review of evidence & recommendations' 👇👇 #CardioSky #diabetes www.frontiersin.org/journals/end...

Checking out of all things work for the next 9 days with @paulsquires.bsky.social. Heading to Salcombe for sea air, coastal walks and yummy food and wine 🫒🍲🥖🥂🍷. Stay tuned for glorious pictures of the English Coast 🌊🌊 #FancyPants are on 😉 #WomeninSTEM #Weekend #Salcombe #England #Coastal

Bracing but beautiful day in Salcombe with @paulsquires.bsky.social ❤️ #Salcombe #Devon #AnnualLeave #womeninSTEM #CardioSky #NephroSky

Our special issue for DiabeticMedicine entitled 'From Bench to Bedside: An integrated and multi-disciplinary approach to tackling diabetic kidney disease' is available online now. 👇👇 #KidneyDisease #Diabetes #NephSky #KidneyResearch #Diabetes #CardioSky onlinelibrary.wiley.com/toc/14645491...

A glorious walk today, albeit a slightly freezing day in Kenilworth. ❄️❄️❄️ #academicsky #cardiosky #nephsky #Warwickshire #saturday #countrylife #womeninSTEM

3 days back at work. Let's just say this wine is well deserved 🤣🤣. Thank heavens I have @paulsquires.bsky.social by my side to keep me sane 😬 #WomeninStem #cardiosky #Nephsky #academiclife #drama #womeninnephro

Metabolite-mediated inter-tissue signalling. Led by Jane Luk & Mark Kearney @unileedsnews.bsky.social in @naturecomms.bsky.social we identify malonic acid as an IGF1R-regulated endothelial-to-adipocyte metabokine mediating adipose metabolism. Great start to 2025. www.nature.com/articles/s41...

Interested in #GLP-1 , #Semaglutide #cardiovascular and #kidneydisease ? 👩‍🔬🥼🧪🧪Just out @thelancet.bsky.social 👇👇. Thanks for sharing @paulsquires.bsky.social 👍 #CardioSky #NephSky #diabetes #kidneys #womeninSTEM

Great read to start 2025 #GLP1 #semaglutide #diabetes #diabetesuk #cardiorenal #GLP1RA www.thelancet.com/journals/lan...

#BHF #diabetes #T2DM #trials #DUK Exciting use of #AI in diabetes diagnosis. BBC News - Hospitals trial AI to spot type 2 diabetes risk www.bbc.com/news/article...

What a Christmas present #KRUK #nephsky #kidneydiseae #kidneytransplant BBC News - 'My former work colleague gave me her kidney' www.bbc.com/news/article...

Following my last post. Inspired. Applications for small grants in #T1DM NOW OPEN. #diabetes #diabetesresearch 👀 👇👇👇 bit.ly/49zskBz

An inspiring story from a brave young lady. #diabetes #womeninstem #T1DM #inspire BBC News - A life-changing device for diabetics www.bbc.com/news/article...

It's beginning to look a lot like Christmas #Cotswolds #lifeofanacademic #academicsky #Christmas #cotswoldlife

Applications for the inaugural EASD Diabetes Technology School are now open! This 3-day event is ideal for healthcare professionals looking to gain expertise in the latest #diabetes technology. Apply by 16 January 2025 👉https://www.easd.org/education/diabetes-tech-school.html #DiabetesCare #CGM #AID

Applications open for several research positions here in Cambridge including evolutionary genetics, genomics and population genetics. www.jobs.cam.ac.uk/job/49389/

Trying to remember I've still got 3 weeks worth of work to do before the festive break (& a preliminary grant application)....feeling oh so twinkly and magical today however✨️👩‍🔬 🎄🎅🥼👨‍🔬🧪🌲🧑‍🎄 #Christmas #Christmastree #AcademicSky #WomeninSTEM #Christmasdecorations #WomeninNephro #nephrosky #cardiosky

GRANT SUBMITTED 🥳🥳🥳. First #Snowball of the season to celebrate....tomorrow the tree goes up 🎄🌲🎅🎄. Looking forward to some festive ✨️. It's been a tough few weeks 🤪 #AcadmicSky #CardioSky #NephSky #christmas #academiclife #festive #snowball #womeninSTEM #weekendvibes #Christmastree

Crosstalk of Hyperglycaemia and Cellular Mechanisms in the Pathogenesis of Diabetic Kidney Disease 👩‍🔬🧪🥼👨‍🔬 #diabetes #nephropathy ##nephrology #kidneydisease #NephSky #type2diabetes 👇👇👇 www.mdpi.com/1422-0067/25...

In people with T2D, effects of GLP1-RA on CV, kidney & mortality outcomes are consistent irrespective of SGLT2i Our meta-analysis of the 3 GLP1RA diabetes clinical outcome trials with the largest prevalent use of SGLT2i in @ahajournals.bsky.social Circulation www.ahajournals.org/doi/10.1161/...

Younger-onset compared with later-onset type 2 diabetes: an analysis of the UK Prospective Diabetes Study (UKPDS) with up to 30 years of follow-up (UKPDS 92) #diabetes #T2DM #type2diabetes #MedSky 👇👇 www.thelancet.com/journals/lan...

#DAPA-HF & #DELIVER pooled analysis: #Dapagliflozin reduced new-onset diabetes by 33% (HR 0.67; P=0.012) in HF patients without DM (n=5623). Meta-analysis of 7 RCTs (n=17,855): #SGLT2i reduced new-onset DM by 26% (HR 0.74; P<0.001) in CV/kidney disease academic.oup.com/eurheartj/ad...

Efficacy and Safety of Sotagliflozin in Patients with Type 1 Diabetes and CKD. 👩‍🔬🔬🧪🥼👨‍🔬. #Type1diabetes #kidneydisease #Nephropathy #SGLT2i #cardioseq #nephseq #cardiorenal. Full details 👇👇👇 journals.lww.com/jasn/abstrac...

More coverage around Semaglutide and it's ability to reduce kidney disease progression by 22% and cardiovascular risk in an analysis involving >85,000 👩‍🔬🧪🥼👨‍🔬. #GLP-1 #semaglutide #diabetes #kidneydisease #Nephropathy #CardioSky #NephSky #MedSky 👇👇👇 www.theguardian.com/science/2024...

Cellular atlases are unlocking the mysteries of the human body @natureportfolio.bsky.social 👩‍🔬🥼👨‍🔬🧪 #MedSky #CardioSky #proteome #CellAtlas #NephSky 👇👇👇 www.nature.com/articles/d41...

The FLOW trial was still producing results at #KidneyWk last month, including findings of an analysis of data assessing #kidney outcomes by #CKD severity. #nephrology #kidneydisease

Worldwide trends in diabetes prevalence and treatment from 1990 to 2022: a pooled analysis of 1108 population-representative studies with 141 million participants 👩‍🔬🔬🥼 #Diabetes #Type1diabetes #Type2diabetes #MedSky #Lancet Full details 👇 www.thelancet.com/journals/lan...

A morning mooch round glorious Bath with @paulsquires.bsky.social ❤️. The perfect mini break to recharge the batteries and the ☀️☀️ even decided to make an appearance 🙏🙌 #AcademicLife #AcademicSky #Bath #Somerset #Cotswolds #cardiosky #NephSky #AnnualLeave

ISN Webinar: How GLP1 receptor agonist evolved from weight management drugs to kidney protective therapy? Speakers Katherine Tuttle and Peter Rossing 👩‍🔬🔬🥼🧪👨‍🔬 #NephSky #NephroSky #CardioSky #cardiorenal #cardiovascular #kidneydisease #diabetes #GLP-1 Full details 👇 www.theisn.org/blog/event/i...

New approaches to acute kidney injury 👩‍🔬🧪👨‍🔬🥼 #kidneydisease #kidneyinjury #AKI #NephroSeq #CardioSeq Full details of new publication 👇👇👇 academic.oup.com/ckj/article/...

Genome-wide association study reveals mechanisms underlying dilated cardiomyopathy and myocardial resilience 👩‍🔬🥼🧪 #CardioSky #Cardiomyopathy #cardiorenal #cardiovascular #cardiovasculardisease 👇👇 www.nature.com/articles/s41...