Terezie Mandakova
@terimandakova.bsky.social
📤 254
📥 104
📝 39
Chromosome explorer 💚 | Plant cytogenomics & genome evolution 🧬🔬🌿 | Proudly @CEITEC_Brno & @sci_muni
reposted by
Terezie Mandakova
Peter van Dijk
3 months ago
A new bioRxiv preprint reports that a team from the Chinese Academy of Agricultural Sciences has synthesised fully penetrant apomictic hybrid rice — a potential game changer for breeding.
doi.org/10.1101/2025...
#Apomixis
#HybridRice
#PlantBreeding
#Agriculture
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Molecular and morphological data, powered by the
#Boechera
Microsatellite Website, revealed the hybrid origins of
#apomictic
triploid Boechera bodiensis - showcasing how genomic tools clarify species boundaries and support plant conservation.
@annbot.bsky.social
academic.oup.com/aob/advance-...
4 months ago
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The updated BrassiBase v2025 is live - a global knowledge platform for Brassicaceae taxonomy, phylogenomics & trait data, now integrated with the Brassi_TEN expert network.
link.springer.com/article/10.1...
4 months ago
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Hybrid zones in Cardamine (Brassicaceae) reveal the formation of diverse triploid hybrids with evolutionary potential. Cardamine rivularis plays a key role as both a driver and a species at risk.
@newphyt.bsky.social
nph.onlinelibrary.wiley.com/doi/10.1111/...
@ceitec.eu
@uebscimuni.bsky.social
4 months ago
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reposted by
Terezie Mandakova
Ian Henderson
4 months ago
Excellent work from
@piotraz.bsky.social
group demonstrating juxtaposition of heterozygous & homozygous regions in maize attracts meiotic recombination to het regions
rdcu.be/eHmn9
@natplants.nature.com
builds from work we did together in Cambridge on Arabidopsis way back in 2015. Great stuff Piotr!
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Enhancing local meiotic crossovers in Arabidopsis and maize through juxtaposition of heterozygous and homozygous regions
Nature Plants - This study discovered that locally confined DNA differences boost crossover rates in both Arabidopsis and maize, revealing a conserved mechanism that can accelerate plant breeding...
https://rdcu.be/eHmn9
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Huge thanks to Malika Ainouche and
@jonathanfwendel.bsky.social
for inviting me to the fantastic
#Polyploidy
conference in Roscoff, Brittany - inspiring talks and wonderful people!
4 months ago
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#Lobularia
maritima (Brassicaceae) is often planted in strips next to vegetable fields in Brittany. It attracts pollinators and beneficial insects, helping to reduce pests and support healthy crops. 🐝🥬
4 months ago
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Late summer vibes in the Tatra Mts, Slovakia.
5 months ago
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Early morning FISHing of Arabidopsis rDNA.
5 months ago
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Thrilled that our “Boechera or not?” paper has been recognized by
@aspbofficial.bsky.social
! Thanks for spotlighting our work!
multibriefs.com/briefs/ASPB/...
add a skeleton here at some point
6 months ago
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So exciting to see Camelina sativa growing in Czech fields! Drought-tolerant, climate-smart, and a promising source of sustainable jet fuel.
#Camelina
#ClimateSmartAg
#Biofuel
#CzechAg
6 months ago
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Propagating the
#Kalanchoe
collection
@sphaeromeria.bsky.social
6 months ago
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Not
#Boechera
! We used genomics, cytogenetics & phylogenetics to reveal that the mysterious Boechera calcarea is actually Parryodes calcarea - a rare Asian member of the Arabideae tribe (Brassicaceae):
www.sciencedirect.com/science/arti...
@ceitec.eu
@uebscimuni.bsky.social
6 months ago
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Mendel’s pea has rolled its way into the Brno university campus for the Mendel Festival!
@ceitec.eu
6 months ago
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When you are obsessed with 5S rDNA…
6 months ago
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reposted by
Terezie Mandakova
Genetics Society of America
6 months ago
Check out this recent article in
#G3journal
!
add a skeleton here at some point
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reposted by
Terezie Mandakova
Piotr Ziolkowski
6 months ago
‼️Can we tune crossover hotspot activity by targeting chromatin modifiers? Absolutely!💥 Our screen shows dCas9-JMJ14 represses crossovers at targeted sites, while VP64 boosts them! 🧬 Check our new preprint:
www.biorxiv.org/content/10.1...
#meiosis4ever
#CRISPR
#Arabidopsis
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https://biorxiv.org/content/10.110…
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🍇 The oldest
#grapevine
in the world — Maribor, Slovenia. Over 400 years old, still growing and producing grapes!
6 months ago
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The 6th B chromosome conference in Olomouc 🇨🇿 in 2026
#6BCC
7 months ago
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reposted by
Terezie Mandakova
André Marques
7 months ago
#🔟
Herklotz, V., Zhang, M., Nascimento, T., et al. Bimodal centromeres in pentaploid dogroses shed light on their unique meiosis Nature (2025)
www.nature.com/articles/s41...
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Bimodal centromeres in pentaploid dogroses shed light on their unique meiosis - Nature
Insights into the dogrose genome and centromeres explain their ability to achieve stable sexual reproduction.
https://www.nature.com/articles/s41586-025-09171-z
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reposted by
Terezie Mandakova
André Marques
about 1 year ago
🧵𝐀 𝐭𝐡𝐫𝐞𝐚𝐝 𝐰𝐢𝐭𝐡 𝐟𝐞𝐚𝐭𝐮𝐫𝐞𝐝 𝐥𝐚𝐛 𝐩𝐮𝐛𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬: 🧵
#1️⃣
Hofstatter, Thangavel, Lux et al. 2022 𝘊𝘦𝘭𝘭: 𝗥𝗲𝗽𝗲𝗮𝘁-𝗯𝗮𝘀𝗲𝗱 𝗵𝗼𝗹𝗼𝗰𝗲𝗻𝘁𝗿𝗼𝗺𝗲𝗿𝗲𝘀 𝗶𝗻𝗳𝗹𝘂𝗲𝗻𝗰𝗲 𝗴𝗲𝗻𝗼𝗺𝗲 𝗮𝗿𝗰𝗵𝗶𝘁𝗲𝗰𝘁𝘂𝗿𝗲 𝗮𝗻𝗱 𝗸𝗮𝗿𝘆𝗼𝘁𝘆𝗽𝗲 𝗲𝘃𝗼𝗹𝘂𝘁𝗶𝗼𝗻
www.cell.com/cell/fulltex...
@gokilavani.bsky.social
#PlantSciences
#Chromosome
#Genomics
#Meiosis4eva
#Centromere
🌱🧬🔬
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Repeat-based holocentromeres influence genome architecture and karyotype evolution
While most eukaryotes contain single regional centromeres, several plant and animal lineages assemble holocentromeres along the entire chromosome length. The assembly of chromosome-scale holocentric g...
https://www.cell.com/cell/fulltext/S0092-8674(22)00797-8
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reposted by
Terezie Mandakova
Mags
7 months ago
Poster is live
#Evol25
add a skeleton here at some point
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We decoded the genome of
#Boechera
falcata, the only Eurasian species in a mostly North American plant group. It helps us understand how it evolved and how it reproduces.
academic.oup.com/g3journal/ad...
@ceitec.eu
@uebscimuni.bsky.social
7 months ago
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Peas in our garden — with a little Mendel inspiration 🌱🧬
7 months ago
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reposted by
Terezie Mandakova
EMPSEB 31
7 months ago
The next talk in Session 7A was given by Petr Janás. He introduced us to how CRISPR-Cas engineering can rewind chromosome evolution in plants!🌿 Thank you for the inspiring talk!
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reposted by
Terezie Mandakova
Ian Henderson
7 months ago
The mutational dynamics of the Arabidopsis centromeres
www.biorxiv.org/content/10.1...
Absolutely stunning new preprint on centromere mutation from @labschneeberger.bsky.social
@plantevolution.bsky.social
@jurriaanton.bsky.social @lisasmith
@plantylisasmith.bsky.social
& colleagues
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The mutational dynamics of the Arabidopsis centromeres
Centromeres are specialized chromosome regions essential for sister chromatid cohesion and spindle attachment during mitosis. Many centromeres comprise highly variable, megabase-scale satellite DNA ar...
https://www.biorxiv.org/content/10.1101/2025.06.02.657473v1
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@ibotcz.bsky.social
smells like peonies. One of the most beautiful places to do research. Maybe only Kew Gardens comes close?
7 months ago
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Visiting
@ibotcz.bsky.social
– grateful for years of collaboration with great colleagues and friends.
7 months ago
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reposted by
Terezie Mandakova
Ian Henderson
7 months ago
A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution
@camplantsci.bsky.social
www.jobs.cam.ac.uk/job/51488/
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Research Assistant / Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant / Research Associate (Fixed Term) in the Department of Plant Sciences at the University of Cambridge.
https://www.jobs.cam.ac.uk/job/51488/
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Proud of my PhD student Petr Janas, who did great and successfully passed the state doctoral exam in Molecular Biology and Genetics. Well done, Petr! 👏🧬
@uebscimuni.bsky.social
@ceitec.eu
7 months ago
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Lady’s slipper orchid (Cypripedium calceolus) in bloom at Strabišov-Oulehla Nature Reserve, CZ.
8 months ago
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Great Boechera project meeting with Duarte Figueiredo from @MPIMP_Potsdam at the @DFG_ICIPS conference in Berlin!
10 months ago
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Excited to be attending the
@icips.bsky.social
conference and grateful for the opportunity to present my talk on the structure and origin of apomixis-associated loci in Boechera.
add a skeleton here at some point
10 months ago
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Paper "Triploid bridges enable gene flow in mixed-ploidy populations of Cardamine amara" published in Molecular Ecology!
doi.org/10.1111/mec....
The study reveals how rare triploids help overcome ploidy barriers and mediate gene flow between diploid and tetraploid populations.
10 months ago
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Adonis vernalis, a sign of spring, blooming in the Větrníky Nature Reserve (CZ) — a golden treasure in the early days of the season.
10 months ago
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Winter hiking in the Beskydy Mts.
11 months ago
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Fantastic review on the evolutionary new allopolyploids!
add a skeleton here at some point
11 months ago
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Californian beauty in full bloom! Triploid apomict
#Boechera
sierraensis showing off in the greenhouse.
11 months ago
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reposted by
Terezie Mandakova
Jana Helsen
12 months ago
Centromere evolution isn't a sudden switch! Our study shows centromere transitions are a step-by-step process driven by a combination of drift and selection. Discover how the kinetochore interface shapes this gradual change in our new preprint 🥳
doi.org/10.1101/2025.01.16.633479
🧵(1/8)
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Closing out 2024 in the stunning Javorníky Mts. Soaking up the snow, the calm, and all the good vibes. Ready for new adventures and an amazing 2025. Let’s make it unforgettable!
about 1 year ago
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reposted by
Terezie Mandakova
Nick Desnoyer
about 1 year ago
In one year, I genetically engineered the boring Arabidopsis into a beautiful ornamental flower 🧬🌹 Here is how and why I gave this model organism a visual upgrade 🧵(1/7)
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Heading to the Academic Senate of Masaryk University @muni_cz - our final meeting of the year! ✍️🎓 Grateful to be part of shaping the future of our university.
#AcademicSenate
about 1 year ago
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reposted by
Terezie Mandakova
Daniel Ibrahim
about 1 year ago
🔺🔺🔺RED TRIANGLE ALERT 🔺🔺🔺 Ever wonder how
#TADs
compare across the tree of life?Look no further & read our Review!!! Find out what genes & 3D chromatin can & can't do in Bacteria! Archeae! Yeast! Plants! Animals! SMCs & RNA-Pol are the only thing they have in common
www.nature.com/articles/s41...
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Evolution and function of chromatin domains across the tree of life - Nature Structural & Molecular Biology
Szalay et al. discuss cross-kingdom similarities and differences in 3D chromatin folding in relation to gene regulation, including in bacteria, archaea, mammals and plants. This comparison reveals cer...
https://www.nature.com/articles/s41594-024-01427-y
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Grateful to have received a 3-year research grant from the Czech Science Foundation
#GACR
to study rDNA evolution! Huge thanks to my incredible co-applicant, Ales Kovarik - writing this proposal together was a true joy. Excited for the journey ahead!
about 1 year ago
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What a day! Morning with rDNA friends at the Institute of Biophysics, Czech Academy of Sciences, and an afternoon with my Boechera team at CEITEC, Masaryk University. Great science all around!
about 1 year ago
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Really enjoyed teaching this semester’s Practical Course in Plant Cytogenetics! 🌿🔬 Such a rewarding experience sharing knowledge and exploring science together.
#PlantCytogenetics
about 1 year ago
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