1) This study from Cornell University tested more than 6000 proteins before and after two exercise tests. It found altered patterns in ME/CFS patients compared to controls, particularly in proteins involved in the immune system, signal transduction, and muscle contraction.

@vladvexler.bsky.social looking and sounding much, much better. I hope he has the capacity to share a health update with us. Covid infections on top of pre-established #ME are leading to extreme exaccerbation of ME symptoms and breathing difficulties in many cases. Vlad's generosity, frankness 1/2

The 2nd thing @binitakane.bsky.social & I discussed was thirst. We barely scratched the surface of this fascinating appetite, explained more in this blog: lc-sc.co.uk/bodily-syste... Including: Blood volume Prostaglandins Acetylcholine Mast cells Dopamine Glutamate & other neurotransmitters 🧵

I just signed the petition to to demand the Government tax the super rich to rebuild our NHS, schools, and other public services. Will you sign too? you.38degrees.org.uk/petitions/ta...

Korean study *just* published (10 Nov 2025) found that wearing kn94 masks (equivalent of ffp2 or n95) is protective against infection by COVID-19. Only 1 healthcare worker infected out of over 180 working for a year with COVID+ patients. Study was done in 2020 and 2021, before vaccines.

🚨 NEXT WEDNESDAY 19 NOVEMBER We’ve been made aware of an upcoming Westminster Hall debate, tabled by @tessamunt.bsky.social, focused on government support for people with ME. If you have the energy - an email to your MP asking them to attend can go a long way 🙏 Template in next post👇

Delighted that I’ve secured a debate in Parliament on ‘Government support for ME’ next Wednesday 19 November. This provides a valuable opportunity for MPs to share views - the first in years. I hope that many MPs will join me. Do encourage yours! #pwME

Q&A on the Photography & Collaboration Arts Collective (PCAC) blog with photographer Jeremy Jeffs @jeremy-jeffs.bsky.social, diagnosed with ME in 1987, discussing his powerful project photographing people living with the illness. www.pcac.ngo/blog/jeremy-...

Tessa Munt MP @tessamunt.bsky.social has managed to secure a debate in Parliament on ‘Government support for ME’ next Wednesday 19 November 2025. This provides a valuable opportunity for MPs to share views. Do encourage your MP to take part. #pwME

Pressure is building. We’re now on the cusp of major tax reform. But the powerful few, who refuse to pay their way are spreading fear, division & lies to stop us. Will you tip the scales in the favour of the many and help us win a fairer economy? taxjustice.uk/afr1-short-c...

Coming to a city or town near you, the Patriotic Millionaires 'tax us, the super-rich' tour bus 🚍 Join us as we travel across the UK, calling for a Budget which taxes wealth, not work. #TaxTheSuperRich

Hello, Working with Survation (independent pollster), PM UK polled UK-based millionaires. They found 80% of millionaires support a two percent tax on wealth over £10 million. Of the millionaires polled who had wealth of £10m plus, 85% of them were in support of it. Continues/2

“Trump & Brexit are not 2 different things. They are the same thing. Same companies. Same data. Same Facebook. Same Russians. Same Cambridge Analytica. Same Robert Mercer. Same Steve Bannon. Same Breitbart. Same Alexander Nix. Same Donald Trump. Same Nigel Farage” @carolecadwalla.bsky.social 👇 #BBC

Systrom: "Many of us in the field..believe that ME/CFS is often, but not always..post-infectious..for not totally clear reasons, there is autoimmunity, which may run amuck on overdrive with associated inflammation...then downstream.those pathways, we think there are some issues with oxygen supply.."

“Rachel Reeves can’t afford not to raise taxes […] But who pays is important because millions are already struggling. The govt pledged not to raise taxes on working people and they don’t have to.” Our very own @jakeatkinson.bsky.social in The @bigissue.com www.bigissue.com/news/politic...

The platforming of this sort of stuff is why I boycott The Hay Festival. Yes, you shouldn't need a diagnosis to get help, but what she says is entirely counterproductive and stigmatising. #OverDiagnosis

The high street: please come don't shop online 🥺 Also the high street: no staff, do your own checkout, remove your own security tag, item you wanted isn't in stock, download an app or you pay more.

Yes $ Health ECONOMICS not CARE. ‘Compared with other psychological treatments, CBT, in particular, has greater treatment effects in terms of reducing the use of medical resources and improving patients’ quality of life and can effectively reduce medical costs.‘ www.tandfonline.com/doi/full/10....

Was lovely to speak with Dr Uy Hoang - who has uploaded over 300,000 photos of the UK's canals and rivers to Google Street View and is ninth in the world by number of uploads - for this piece. www.londonworld.com/news/people/...

Would like to see this study repeated using patients who have ME as defined by the International Consensus Criteria (ICC). I think many of us in the ME-ICC group deal with MCAS and orthostatic intolerance.

Yay! A fresh round of baseless scaremongering. Now, the noisy minority of greedy super-rich are telling us settling up charges will mean no one will invest or start business in the UK. Just like they don't elsewhere with exit taxes like **checks notes** USA, France, Germany, Canada, Australia...

The resignations are being painted as being because the BBC is culturally Marxist and has a leftist bias. Facts don’t seem to matter anymore.

Note that still in post at the BBC is Robbie Gibb, who helped set up GB News, and John McAndrew, formerly director of news and programmes at GB News.

Robbie Gibb who cancelled a BBC investigation into Farage's Leave dot EU campaign shortly before the EU Ref Arron Banks thanked him for it "Robbie Gibb is being quite helpful and says he’s trying to hose it down." - @channel4news.bsky.social in 2019

Once every 20 years or so, the director-general of the BBC is forced to resign for being insufficiently rightwing. Alastair Milne in 1987. Greg Dyke in 2004. Tim Davie in 2025. The great irony is that the BBC was in all cases profoundly biased towards established power. But just not biased enough …

Yes, absolutely there is an impartiality crisis at the BBC. But it's not the one the billionaire media insists it is. novaramedia.com/2025/06/16/b...

As of November 5th, it estimated that U.S.A.I.D.’s dismantling has already caused the deaths of six hundred thousand people, two-thirds of them children. The short documentary “Rovina’s Choice” tells the story of what goes when aid goes. #USAID

The final delivery plan for #MEcfs recommended 3 NHS e-learning modules for HCPs developed by the Department of Health and Social Care with patient groups. These should help shift attitudes. www.e-lfh.org.uk/programmes/m...

Ten years ago in Paris, every country pledged bold action to cut emissions and tackle the climate crisis. Since then, the super rich have burned through twice as much carbon pollution as the bottom 50% of humanity combined. It’s time to #MakeRichPollutersPay 👉 bit.ly/47Lncer#MakeRichPollutersPay

USA Photo of the year

Astonishing video, worth watching in full.

You'd make a great horror writer man. It inspired me a bit if you don't mind.

applying for jobs again

The government has STILL not cleared out the highly partisan decision-makers imposed on the BBC by the Tories. Starmer and co are so amazingly spineless and feeble. www.theguardian.com/politics/202...

Nigel Farage used to believe in reforming the voting system, now he's rowed back because it no longer benefits him. We will keep fighting for a fair votes, not because it benefits us but because it's right for the country.

The headline is a bit misleading. Test not quite ready for public use. I clarify here: open.substack.com/pub/colleens...

🔥 Important: For attention of all students and working class people, and their parents 💯 ➡️ Everyone - Please share 🙏👍 youtube.com/shorts/AZ5RS... #TaxTheRich

@swastrosarah.bsky.social is this ammunition for Justice4ME? The author of the Keep britain working review literally pushing BPS as a way to force disabled people into work.

Three children were killed by lawn darts in the 70’s and they were banned in the US. ChatGPT has caused how many deaths at this point? If corporations are people, why aren’t we holding them criminally liable?

Getting ready for Day 2 at the #ICanCME2025 conference! I'll be delivering a talk about neurodiversity in #pwME and IACCs in general. Hope to see you there!

And coverage for Day 1 of the #ICanCMEConference by the @icancmeresearch.bsky.social. Features a link to my live tweets. simonspichak.beehiiv.com/p/icancme-da...

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1) Interesting interview of Prof. Brian Hughes by David Tuller. In his new book Hughes argues that psychology is not woke but that its methods are essentially conservative because it focuses on an individualistic view and ignores social context.

The world lost half a trillion dollars to a US-backed global gag order that stopped countries from revealing the names of multinational corporations found shifting profit into tax havens #NameTheTaxCheaters #TaxJustice2025 bit.ly/taxjustice25

Perfect analyyas usual 👍 youtu.be/Jk0nUUqG_Ag

@meactionuk.bsky.social @meassociation.org.uk please share to your networks. This is a genuine opportunity to influence national policy - especially on Adult Social Care and spurious Mental Health Act assessments (which are mostly led by Social Worker AMHPs).

The review is open to everyone. Provide your evidence here. Strongly recommend every family persecuted by social workers too lazy to read NICE G206 make their voices heard. www.gov.uk/government/c...

‘If you’re disabled, you’re not ill.’ Sir Charlie Mayfield (author of the Keep Britain Working review) This is who’s shaping UK disability employment policy. Shocking, he doesn’t even understand the basics. I’m disabled because I’m chronically ill with #MECFS.

This has to stop. First Elon, then Farage's wish come true for UK Corporations We don't need trillionaires when half of the world is in poverty or starving. Utter madbness #TaxTheRich #Neoliberalism gone mad. news.sky.com/story/elon-m...

At last a political party that recognises that the correct way to get people working again is to invest in research for treatments and stop them from getting sick in the first place 👍 #pwME #pwLC #BoldPolitics