This is very sad for the US but incredibly smart by Norway

#YorkshireDales #waterfall

Summit of #Ingleborough peak in #YorkshireDales

#Ingleborough Peak in #YorkshireDales

Elections have consequences

I wish things were boring again. Uneventful. Unremarkable. Dull even. Nothing happening that's noteworthy. Interesting times are vastly overrated.

Must read: How reductions in force and a planned reorganization of #FDA could dramatically reduce the agency's ability to perform essential functions -- from my colleague @steveusdin.bsky.social www.biocentury.com/article/655559

Buckle up.

From our 2025 #BioCentury financial markets preview: www.biocentury.com/article/654637

There are 33m companies in the USA. Only 21k employe 500 or more. And they only make up 23% of workers. Trump and Elon are ignoring the more than 32m entrepreneurs that can't afford to build a new factory or pay tariffs or absorb cancelled contracts.

"And like that, the market is gone" #tariffs

The 22nd Amendment prohibits US presidents from serving more than two terms

Very interesting study. What is your DHRPS? www.ahajournals.org/doi/epdf/10....

Up is down, blue is red, night is day, south is north.

Oral Ozempic reduced major adverse cardiovascular events in a large randomized trial of 9,650 participants with T2 diabetes and high-risk @nejm.org #ACC25 www.nejm.org/doi/full/10....

Cuts at #FDA put the agency at risk of missing PDUFA goals - from my colleague @steveusdin.bsky.social : www.biocentury.com/article/655466

A Pentagon-wide advisory that went out one week ago warns against using the Signal, the messaging app, even for unclassified information.

Thanks to global immunisation efforts, an estimated 154 million lives have been saved over the past 50 years 🌎 🤝 That’s equivalent to 6 lives every minute. #CelebrateVaccines

My latest on the #Zealand and #Roche deal for amylin agonist pretrelintide: www.biocentury.com/article/655330

With the #Roche and #Zealand deal for up to $5.3B for #amylin agonist #petrelintide in #obesity, re-upping my story from last week on the promise of amylin in #obesity: www.biocentury.com/article/655255

With the #Roche and #Zealand deal for up to $5.3B for #amylin agonist #petrelintide in #obesity, re-upping my story from last week on the promise of amylin in #obesity: www.biocentury.com/article/655255

Nightmarish stuff in here.

👀

#bluesky Saturday⛱️

@minakimes.bsky.social PARADISE 🤯

Could amylin outshine GLP-1 in obesity? 🔬 Will amylin reshape the obesity treatment landscape? 📊 Sure feels that way. Novo, Lilly, and AZ are already in the game, and AbbVie just dropped $350M on an amylin asset. 📖 Access to the full report here: www.biocentury.com/article/6552...

Holy shit!! Trump just slipped on live TV that he lost the 2020 presidential election. Trump would HATE it if this goes viral:

#GLP1 sales continue to boom thanks to #obesity market expansion #biosky #medsky www.biocentury.com/article/655202

Still waiting for RFK to clearly and unambiguously state that the MMR shot is *safe*, does not cause autism is the best way to protect yourself & your community from measles. In the meantime, my piece from last week (gift link):

Aspirin prevents metastasis by limiting platelet TXA2 suppression of T cell immunity www.nature.com/articles/s41...

Jazz Pharma is adding an oncology product via the takeout of Chimerix for ~$935m, 72% premium. Dordaviprone, under review for a type of brain cancer, has a PDUFA date of Aug. 18; it’s PRV-eligible too. www.globenewswire.com/news-release...

Just an obvious point that anyone with the inside word on when these these total reversals are going to be announced is in a position to make almost limitless amounts of money. Don't forget that given the kind of people who make up this administration.

The $VIX volatility index is up 24% in the past week and 40% the past month

Good morning #biosky! I had a good conversation with Sofinnova's Antoine Papiernik -- two conversations, as it turned out -- about how the firm expects to deploy €1.2 billion in fresh cash, raised in a tough environment. Story here: www.biocentury.com/article/6552...

Harrison, whose plasma contained a rare antibody, rolled up his sleeve 1,173 times from 1954 to 2018. The Australian is credited with helping 2.4 million babies and advancing scientific research.

⚡️ Trump to discuss potential suspension, cancellation of military aid for Ukraine on March 3. An unnamed administration official told NYT that Trump will meet on March 3 with his top national security aides, including Marco Rubio and Pete Hegseth.

KYIV INDEPENDENT: “It’s time to say it plainly. America’s leadership has switched sides in the war. The American people have not, and they should speak up.” kyivindependent.com/editorial-a-...

Francis Collins, the NIH Director for 12 years, led the Human Genome Project and other NIH efforts for 32 years, resigned today. Key words from his resignation letter www.nytimes.com/2025/03/01/u...

Your dignity honors the bravery of the Ukrainian people. Be strong, be brave, be fearless. You are never alone, dear President Zelenskyy. We will continue working with you for a just and lasting peace.

Do You Need a Measles Booster? With outbreaks spreading in the Southwest, it’s a good time to check your vaccination status. www.nytimes.com/2025/02/27/w...

Okay... we feel like we say this every week but *a lot* of stuff happened. Let's break it down, starting with @brbarrett.bsky.social on why the DOGE takeover is worse than you think... (sorry, but you gotta read this one.)

US consumer #inflation expectations highest since 1995. Anyone still think #tariffs don't drive inflation higher?

The Trump administration terminates funding for polio, HIV, malaria and nutrition programs around the world. “People will die,” said Dr. Catherine Kyobutungi of the African Population and Health Research Center, “but we will never know, because even the programs to count the dead are cut.”

The People's Union USA, a grassroots group, is calling on Americans to join a national boycott by not shopping for 24 hours on Friday.

Inside the collapse of NIH: www.msn.com/en-us/politi...

Tesla’s shareholders just lost another $38,640,000,000 today — a total $TSLA loss of $600 billion since December. Tesla’s CEO was not in the office. In literally any other public company ever, this would be the point where the CEO gets fired.

I can't imagine a world in which we would want a Congrssional majority to be deciding which medicines get approved. Science SHOULD be apolitical