Happy to finally show our story of the connection between nucleoid conformation, transcription & predation in our favorite predator Bdellovibrio bacteriovorus. 🧵 1/n

📝New preprint! #MicroSky 🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy. 🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation. www.biorxiv.org/content/10.1...

Cool work by @mkjos.bsky.social Daniel Straume showing that the competence-induced peptidoglycan hydrolase LytF promotes pilus extrusion, thereby enhancing the efficiency of DNA uptake in S, sanguinis. Is this also a major function of the pneumococcal CbpD fratricide? www.biorxiv.org/content/10.1...

OUT NOW: Inducible transposon mutagenesis identifies bacterial fitness determinants during infection in mice #microsky 🧪 www.nature.com/articles/s41...

Check out the new paper by my fantastic Lab neighbour @tunglejic.bsky.social and superstar postdoc @tommclean.bsky.social about long-range gene silencing by the CTPase KorB. Congrats to the whole Team!

Confirmed speakers for the next Great Wall Symposium is coming along! thegreatwall-symposium.org/program/ Abstracts will open next week 15th so start thinking! September 15-17th, Catania, Sicily Its a Microbiological opportunity you cant refuse!

Very interesting study showing that the large bacterial bottlenecks observed during pneumococcal pneumonia are caused by the Blp bacteriocins and that this interspecies killing liberates pneumolysin triggering inflammation for optimal bacterial replication in the lung. www.nature.com/articles/s42...

Really proud of our new paper, my first as last author. We explored the importance of homologous recombination genes in transformation and genotoxic stress tolerance during competence. Give it a read/like! 🙂 journals.asm.org/doi/10.1128/...

Great review by @pinholab.bsky.social and Simon Foster on the current knowledge regarding growth, elongation and division of Staphylococcus aureus www.annualreviews.org/content/jour...

Straight from the cellars of NIPH, we have a paper out on pneumococcal lineage (GPSC) dynamics in response to childhood vaccination. Resuscitating freeze-dried cultures was a substantial effort, but worked surprisingly well. Have a look if interested! genomemedicine.biomedcentral.com/articles/10....

o hello new followers! I'm Renske, and our very fresh lab in Groningen works on the bacterial predator Bdellovibrio bacteriovorus. We're interested in what tools Bdello uses to eat their prey, the knife & fork, tongue and saliva, so to say. I occasionally post pictures of my knitting work too

Great collaboration with @mortenkj.bsky.social to figure out which genes are required for Staphylococcus aureus to live in milk. Important to know due to Staphs ability to cause bovine mastitis and food poisoning. #MicroSky www.biorxiv.org/content/10.1...

Genome-wide CRISPRi screens for high-throughput fitness quantification and identification of determinants for dalbavancin susceptibility in Staphylococcus aureus #mSystemsJ from @mortenkj.bsky.social and @jwveening.bsky.social eening journals.asm.org/doi/10.1128/...